Motif ID: FOXN1.p2

Z-value: 0.495


Transcription factors associated with FOXN1.p2:

Gene SymbolEntrez IDGene Name
FOXN1 8456 forkhead box N1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
FOXN1chr17_+_268509580.413.2e-01Click!


Activity profile for motif FOXN1.p2.

activity profile for motif FOXN1.p2


Sorted Z-values histogram for motif FOXN1.p2

Sorted Z-values for motif FOXN1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of FOXN1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chrX_-_106960028 0.436 TSC22D3
TSC22 domain family, member 3
chr19_+_14544216 0.332 PKN1
protein kinase N1
chr2_+_28113598 0.323 BRE
brain and reproductive organ-expressed (TNFRSF1A modulator)
chrX_-_106959597 0.303 NM_001015881
TSC22D3
TSC22 domain family, member 3
chr7_-_50860665 0.296 GRB10
growth factor receptor-bound protein 10
chr19_+_14544100 0.288 NM_002741
PKN1
protein kinase N1
chr2_+_28113612 0.280 BRE
brain and reproductive organ-expressed (TNFRSF1A modulator)
chr2_+_28113481 0.275 NM_199193
NM_199194
NM_004899
NM_199191
NM_199192
BRE




brain and reproductive organ-expressed (TNFRSF1A modulator)




chr10_+_31607419 0.256 ZEB1
zinc finger E-box binding homeobox 1
chr1_+_78444922 0.227 DNAJB4
DnaJ (Hsp40) homolog, subfamily B, member 4
chr2_+_28113655 0.214 BRE
brain and reproductive organ-expressed (TNFRSF1A modulator)
chrX_-_153775427 0.213 G6PD
glucose-6-phosphate dehydrogenase
chr5_+_179247903 0.213 SQSTM1
sequestosome 1
chr5_+_179248089 0.200 SQSTM1
sequestosome 1
chr17_-_43045612 0.196 NM_006688
C1QL1
complement component 1, q subcomponent-like 1
chr5_+_179247911 0.196 SQSTM1
sequestosome 1
chr2_-_28113211 0.193 NM_022128
RBKS
ribokinase
chr5_+_172261220 0.192 NM_001031711
ERGIC1
endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1
chr10_+_72163860 0.186 NM_004096
EIF4EBP2
eukaryotic translation initiation factor 4E binding protein 2
chr8_+_38243958 0.182 NM_001199659
NM_144652
LETM2

leucine zipper-EF-hand containing transmembrane protein 2


Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 30 entries
enrichment   p-value GO term description
2.37 1.12e-02 GO:0000375 RNA splicing, via transesterification reactions
2.28 4.75e-02 GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
2.28 4.75e-02 GO:0000398 nuclear mRNA splicing, via spliceosome
1.84 4.76e-03 GO:0016071 mRNA metabolic process
1.77 2.79e-02 GO:0044265 cellular macromolecule catabolic process
1.62 2.63e-02 GO:0046907 intracellular transport
1.61 3.23e-04 GO:0044248 cellular catabolic process
1.54 4.93e-05 GO:0006996 organelle organization
1.52 6.31e-05 GO:0016070 RNA metabolic process
1.50 8.33e-09 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.50 2.23e-03 GO:0009056 catabolic process
1.50 3.51e-02 GO:0010604 positive regulation of macromolecule metabolic process
1.49 1.76e-02 GO:0051641 cellular localization
1.48 1.48e-02 GO:0033036 macromolecule localization
1.46 3.54e-05 GO:0090304 nucleic acid metabolic process
1.40 1.98e-06 GO:0034641 cellular nitrogen compound metabolic process
1.40 1.46e-02 GO:0010467 gene expression
1.39 1.65e-04 GO:0071842 cellular component organization at cellular level
1.38 1.60e-04 GO:0071841 cellular component organization or biogenesis at cellular level
1.37 1.64e-05 GO:0006807 nitrogen compound metabolic process

Gene overrepresentation in compartment category:

Showing 1 to 20 of 27 entries
enrichment   p-value GO term description
2.16 1.24e-04 GO:0005815 microtubule organizing center
1.84 2.54e-05 GO:0015630 microtubule cytoskeleton
1.81 1.84e-03 GO:0030529 ribonucleoprotein complex
1.79 8.90e-03 GO:0044427 chromosomal part
1.69 1.59e-02 GO:0005694 chromosome
1.60 6.77e-06 GO:0005654 nucleoplasm
1.57 1.04e-07 GO:0031981 nuclear lumen
1.51 4.77e-08 GO:0070013 intracellular organelle lumen
1.49 1.03e-07 GO:0031974 membrane-enclosed lumen
1.49 1.79e-07 GO:0043233 organelle lumen
1.46 3.54e-06 GO:0044428 nuclear part
1.37 2.99e-07 GO:0032991 macromolecular complex
1.36 3.40e-14 GO:0005634 nucleus
1.36 2.75e-03 GO:0005829 cytosol
1.35 1.71e-04 GO:0043228 non-membrane-bounded organelle
1.35 1.71e-04 GO:0043232 intracellular non-membrane-bounded organelle
1.30 1.34e-03 GO:0043234 protein complex
1.28 2.59e-08 GO:0044446 intracellular organelle part
1.27 7.57e-08 GO:0044422 organelle part
1.23 9.33e-13 GO:0043227 membrane-bounded organelle

Gene overrepresentation in function category:

Showing 1 to 4 of 4 entries
enrichment   p-value GO term description
1.97 4.47e-02 GO:0016881 acid-amino acid ligase activity
1.72 4.79e-02 GO:0016874 ligase activity
1.24 1.39e-09 GO:0005515 protein binding
1.11 3.85e-06 GO:0005488 binding