Motif ID: GATA6.p2

Z-value: 0.720


Transcription factors associated with GATA6.p2:

Gene SymbolEntrez IDGene Name
GATA6 2627 GATA binding protein 6

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
GATA6chr18_+_197494030.801.8e-02Click!


Activity profile for motif GATA6.p2.

activity profile for motif GATA6.p2


Sorted Z-values histogram for motif GATA6.p2

Sorted Z-values for motif GATA6.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of GATA6.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr11_-_115088628 0.990 CADM1
cell adhesion molecule 1
chr20_+_58251715 0.857 NM_001199506
PHACTR3
phosphatase and actin regulator 3
chr10_-_129691202 0.749 NM_152311
CLRN3
clarin 3
chr8_+_124194751 0.713 NM_032899
NM_207006
FAM83A

family with sequence similarity 83, member A

chr19_-_51523272 0.695 NM_002776
NM_001077500
KLK10

kallikrein-related peptidase 10

chr8_+_124194873 0.582 FAM83A
family with sequence similarity 83, member A
chr4_-_15939949 0.538 FGFBP1
fibroblast growth factor binding protein 1
chr12_+_107974633 0.537 NM_001017523
BTBD11
BTB (POZ) domain containing 11
chr3_+_148583042 0.515 NM_001870
CPA3
carboxypeptidase A3 (mast cell)
chr18_+_19749403 0.488 NM_005257
GATA6
GATA binding protein 6
chr5_+_145316120 0.451 NM_152550
SH3RF2
SH3 domain containing ring finger 2
chr1_-_209825673 0.435 NM_001127641
LAMB3
laminin, beta 3
chr6_+_31674639 0.433 NM_001003693
LY6G6F
lymphocyte antigen 6 complex, locus G6F
chr11_-_58343308 0.388 NM_004811
LPXN
leupaxin
chr6_-_2840683 0.388 SERPINB1
serpin peptidase inhibitor, clade B (ovalbumin), member 1
chr1_-_24469571 0.362 NM_021258
IL22RA1
interleukin 22 receptor, alpha 1
chr5_+_131409484 0.336 NM_000758
CSF2
colony stimulating factor 2 (granulocyte-macrophage)
chr11_-_124310980 0.330 NM_012378
OR8B8
olfactory receptor, family 8, subfamily B, member 8
chr6_-_11779279 0.323 NM_001143948
NM_032744
C6orf105

chromosome 6 open reading frame 105

chr6_-_13408368 0.320 NM_001242630
GFOD1
glucose-fructose oxidoreductase domain containing 1
chr3_+_189507448 0.318 NM_001114980
NM_001114981
NM_001114982
TP63


tumor protein p63


chr2_+_102927961 0.314 NM_016232
IL18R1
IL1RL1
interleukin 18 receptor 1
interleukin 1 receptor-like 1
chrX_-_78623006 0.298 NM_001171581
NM_004867
ITM2A

integral membrane protein 2A

chr10_+_118187381 0.295 NM_001011709
PNLIPRP3
pancreatic lipase-related protein 3
chr8_+_32579350 0.284 NM_001159996
NRG1
neuregulin 1
chr3_-_189840225 0.280 NM_001134418
LEPREL1
leprecan-like 1
chr6_+_12290528 0.279 NM_001168319
NM_001955
EDN1

endothelin 1

chr7_-_142659412 0.275 NM_000420
KEL
Kell blood group, metallo-endopeptidase
chr7_-_142659397 0.274 KEL
Kell blood group, metallo-endopeptidase
chr10_-_116418056 0.271 NM_002313
ABLIM1
actin binding LIM protein 1
chr18_-_28742744 0.270 NM_004948
NM_024421
DSC1

desmocollin 1

chr1_-_42384326 0.257 HIVEP3
human immunodeficiency virus type I enhancer binding protein 3
chr10_+_24755459 0.250 KIAA1217
KIAA1217
chr1_-_209825797 0.249 NM_000228
LAMB3
laminin, beta 3
chr8_-_38008332 0.246 NM_000349
STAR
steroidogenic acute regulatory protein
chr11_-_57148602 0.244 NM_006093
PRG3
proteoglycan 3
chr17_-_39280377 0.243 NM_031854
KRTAP4-12
keratin associated protein 4-12
chr1_+_154293568 0.242 NM_080429
AQP10
aquaporin 10
chr7_+_86273219 0.237 NM_000840
GRM3
glutamate receptor, metabotropic 3
chr5_+_166711842 0.221 NM_001122679
ODZ2
odz, odd Oz/ten-m homolog 2 (Drosophila)
chr4_+_15376174 0.216 NM_001135171
C1QTNF7
C1q and tumor necrosis factor related protein 7
chr11_-_116708334 0.215 NM_000039
APOA1
apolipoprotein A-I
chr14_-_94849552 0.215 SERPINA1
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
chrX_+_44703248 0.214 NM_022076
DUSP21
dual specificity phosphatase 21
chr3_+_130569368 0.214 NM_001199180
NM_001199181
NM_001199182
ATP2C1


ATPase, Ca++ transporting, type 2C, member 1


chr1_+_202172863 0.211 NM_021636
LGR6
leucine-rich repeat containing G protein-coupled receptor 6
chr1_-_226187027 0.209 C1orf55
chromosome 1 open reading frame 55
chr10_-_116444374 0.207 NM_001003407
NM_001003408
ABLIM1

actin binding LIM protein 1

chr10_-_14816895 0.207 NM_031453
FAM107B
family with sequence similarity 107, member B
chr3_-_194188967 0.206 NM_024524
ATP13A3
ATPase type 13A3
chr1_-_226187019 0.204 C1orf55
chromosome 1 open reading frame 55
chr8_-_20040612 0.201 NM_001135691
NM_001142324
NM_001142325
NM_003053
SLC18A1



solute carrier family 18 (vesicular monoamine), member 1



chr5_+_68800003 0.198 NM_001205255
OCLN
occludin
chr19_+_39687600 0.198 NM_001001414
NCCRP1
non-specific cytotoxic cell receptor protein 1 homolog (zebrafish)
chr18_-_44561967 0.197 NM_016427
TCEB3B
transcription elongation factor B polypeptide 3B (elongin A2)
chr9_+_35673852 0.195 NM_001216
CA9
carbonic anhydrase IX
chrX_-_31526414 0.193 NM_004014
DMD
dystrophin
chr1_-_226186987 0.188 C1orf55
chromosome 1 open reading frame 55
chr11_+_34642587 0.188 NM_001206615
NM_012153
EHF

ets homologous factor

chr11_-_59612925 0.188 NM_005142
GIF
gastric intrinsic factor (vitamin B synthesis)
chr17_+_38171613 0.184 NM_000759
NM_001178147
NM_172219
NM_172220
CSF3



colony stimulating factor 3 (granulocyte)



chr2_+_207804277 0.183 NM_173077
CPO
carboxypeptidase O
chr1_-_226187055 0.183 NM_152608
C1orf55
chromosome 1 open reading frame 55
chr5_-_150948504 0.182 NM_001447
FAT2
FAT tumor suppressor homolog 2 (Drosophila)
chr12_-_120765555 0.176 NM_000928
PLA2G1B
phospholipase A2, group IB (pancreas)
chr1_+_15272414 0.171 NM_001017999
KAZN
kazrin, periplakin interacting protein
chr19_-_13213973 0.170 NM_005583
LYL1
lymphoblastic leukemia derived sequence 1
chr6_+_132859426 0.169 NM_175057
TAAR9
trace amine associated receptor 9 (gene/pseudogene)
chr1_+_32043745 0.169 NM_001204415
TINAGL1
tubulointerstitial nephritis antigen-like 1
chr12_+_113344811 0.166 OAS1
2'-5'-oligoadenylate synthetase 1, 40/46kDa
chr2_-_165551178 0.165 COBLL1
COBL-like 1
chr10_-_123353330 0.163 NM_001144913
NM_001144914
FGFR2

fibroblast growth factor receptor 2

chr2_-_40739570 0.163 NM_001112802
SLC8A1
solute carrier family 8 (sodium/calcium exchanger), member 1
chr6_+_29274402 0.155 NM_030946
OR14J1
olfactory receptor, family 14, subfamily J, member 1
chr19_+_7741934 0.155 NM_174918
C19orf59
chromosome 19 open reading frame 59
chr21_+_39628869 0.155 NM_170736
KCNJ15
potassium inwardly-rectifying channel, subfamily J, member 15
chr2_-_69098502 0.154 NM_014482
BMP10
bone morphogenetic protein 10
chrX_+_119495939 0.152 NM_001142447
NM_012069
ATP1B4

ATPase, Na+/K+ transporting, beta 4 polypeptide

chr16_+_71560022 0.151 NM_005769
NM_001166395
CHST4

carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4

chr10_-_123353771 0.148 NM_001144916
FGFR2
fibroblast growth factor receptor 2
chr1_+_87595526 0.148 LOC339524
uncharacterized LOC339524
chr17_-_17480325 0.146 PEMT
phosphatidylethanolamine N-methyltransferase
chr12_+_113344738 0.146 NM_001032409
NM_002534
NM_016816
OAS1


2'-5'-oligoadenylate synthetase 1, 40/46kDa


chr11_-_19082227 0.146 NM_054030
MRGPRX2
MAS-related GPR, member X2
chr4_-_40517913 0.142 NM_019027
RBM47
RNA binding motif protein 47
chr21_+_43823970 0.142 NM_001001895
NM_001243467
NM_018961
UBASH3A


ubiquitin associated and SH3 domain containing A


chr2_+_113885145 0.141 IL1RN
interleukin 1 receptor antagonist
chr14_+_21525980 0.138 NM_138331
RNASE8
ribonuclease, RNase A family, 8
chr4_-_123377471 0.137 NM_000586
IL2
interleukin 2
chr6_-_49604524 0.135 NM_000324
RHAG
Rh-associated glycoprotein
chr2_+_90077732 0.135


chr10_+_118350470 0.131 NM_006229
PNLIPRP1
pancreatic lipase-related protein 1
chr12_-_15091441 0.131 NM_152321
ERP27
endoplasmic reticulum protein 27
chr11_-_47374221 0.128 NM_000256
MYBPC3
myosin binding protein C, cardiac
chr10_-_116444112 0.128 ABLIM1
actin binding LIM protein 1
chrX_+_78003205 0.124 NM_005296
LPAR4
lysophosphatidic acid receptor 4
chrX_-_24690740 0.122 NM_001163264
PCYT1B
phosphate cytidylyltransferase 1, choline, beta
chr3_-_119379269 0.121 NM_022135
POPDC2
popeye domain containing 2
chr16_-_71318761 0.121 FTSJD1
FtsJ methyltransferase domain containing 1
chr19_-_13213513 0.121 LYL1
lymphoblastic leukemia derived sequence 1
chr12_+_45686465 0.119 NM_001142678
ANO6
anoctamin 6
chr7_+_150690838 0.118 NM_001160109
NM_001160110
NM_001160111
NOS3


nitric oxide synthase 3 (endothelial cell)


chr1_-_156399183 0.117 NM_006365
C1orf61
chromosome 1 open reading frame 61
chr1_-_116383692 0.117 NM_005599
NHLH2
nescient helix loop helix 2
chr11_+_34642651 0.117 EHF
ets homologous factor
chr19_+_14138959 0.115 NM_080864
RLN3
relaxin 3
chr22_-_37584254 0.115 NM_031910
NM_182486
C1QTNF6

C1q and tumor necrosis factor related protein 6

chr19_-_35992798 0.115 NM_001035516
DMKN
dermokine
chr5_+_179220985 0.114 NM_145867
LTC4S
leukotriene C4 synthase
chr1_-_26393984 0.113 NM_032588
TRIM63
tripartite motif containing 63
chr7_-_44180911 0.112 NM_021223
MYL7
myosin, light chain 7, regulatory
chr5_-_33984688 0.111 NM_001012509
NM_016180
SLC45A2

solute carrier family 45, member 2

chr5_-_16742336 0.111 MYO10
myosin X
chr11_+_121461070 0.111 SORL1
sortilin-related receptor, L(DLR class) A repeats containing
chr11_-_57195052 0.110 NM_017611
SLC43A3
solute carrier family 43, member 3
chr22_-_43089856 0.110 A4GALT
alpha 1,4-galactosyltransferase
chr1_+_81771844 0.110 LPHN2
latrophilin 2
chr19_-_12997956 0.110 NM_006563
KLF1
Kruppel-like factor 1 (erythroid)
chr11_+_10477480 0.108 NM_001025390
AMPD3
adenosine monophosphate deaminase 3
chr12_+_13043955 0.108 NM_003979
GPRC5A
G protein-coupled receptor, family C, group 5, member A
chr17_-_47841468 0.108 FAM117A
family with sequence similarity 117, member A
chr8_-_124749573 0.107 NM_001003954
NM_004306
ANXA13

annexin A13

chr19_-_48547180 0.106 NM_019855
CABP5
calcium binding protein 5
chr16_+_56817367 0.104 NM_001242796
NUP93
nucleoporin 93kDa
chr9_-_117692874 0.103 NM_001244
NM_001252290
TNFSF8

tumor necrosis factor (ligand) superfamily, member 8

chr2_+_158958381 0.103 NM_173355
UPP2
uridine phosphorylase 2
chr8_-_15095791 0.103 NM_139167
SGCZ
sarcoglycan, zeta
chr1_-_116311330 0.102 CASQ2
calsequestrin 2 (cardiac muscle)
chr16_+_617010 0.102 NM_176677
NHLRC4
PIGQ
NHL repeat containing 4
phosphatidylinositol glycan anchor biosynthesis, class Q
chr15_-_34610928 0.101 NM_005135
SLC12A6
solute carrier family 12 (potassium/chloride transporters), member 6
chr9_+_125281418 0.101 NM_001004452
OR1J4
olfactory receptor, family 1, subfamily J, member 4
chr10_+_75673346 0.100 PLAU
plasminogen activator, urokinase
chr20_+_31669317 0.100 NM_182519
BPIFB4
BPI fold containing family B, member 4
chr11_+_92085261 0.100 NM_001008781
FAT3
FAT tumor suppressor homolog 3 (Drosophila)
chr1_-_116311398 0.099 NM_001232
CASQ2
calsequestrin 2 (cardiac muscle)
chr2_+_106432922 0.099 NCK2
NCK adaptor protein 2
chr5_+_34687663 0.099 NM_001145523
RAI14
retinoic acid induced 14
chr3_-_112564789 0.098 NM_001008784
NM_001199215
CD200R1L

CD200 receptor 1-like

chr16_+_56899118 0.097 NM_000339
NM_001126107
NM_001126108
SLC12A3


solute carrier family 12 (sodium/chloride transporters), member 3


chr5_-_24645084 0.096 NM_006727
CDH10
cadherin 10, type 2 (T2-cadherin)
chr19_+_50691437 0.096 MYH14
myosin, heavy chain 14, non-muscle
chr10_-_45474210 0.096 NM_007021
C10orf10
chromosome 10 open reading frame 10
chr8_-_95449131 0.096 NM_001205263
RAD54B
RAD54 homolog B (S. cerevisiae)
chr18_-_64271215 0.095 NM_021153
CDH19
cadherin 19, type 2
chr15_-_52030162 0.095 NM_153374
LYSMD2
LysM, putative peptidoglycan-binding, domain containing 2
chr1_+_46640748 0.094 NM_005727
TSPAN1
tetraspanin 1
chr1_-_114429996 0.094 BCL2L15
BCL2-like 15
chr11_-_16430425 0.093 NM_001145811
SOX6
SRY (sex determining region Y)-box 6
chr7_-_83824216 0.093 NM_006080
SEMA3A
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr7_-_37024664 0.092 NM_001039459
ELMO1
engulfment and cell motility 1
chr13_+_32313678 0.092 NM_001166058
NM_130806
RXFP2

relaxin/insulin-like family peptide receptor 2

chr20_-_14318200 0.092 NM_013281
NM_198391
FLRT3

fibronectin leucine rich transmembrane protein 3

chr2_+_113885137 0.092 NM_173842
IL1RN
interleukin 1 receptor antagonist
chr1_-_114430168 0.091 NM_001010922
BCL2L15
BCL2-like 15
chr6_+_130339715 0.089 NM_001007102
NM_032438
L3MBTL3

l(3)mbt-like 3 (Drosophila)

chr6_-_33168448 0.088 RXRB
retinoid X receptor, beta
chr11_+_131240370 0.087 NM_001048209
NTM
neurotrimin
chr4_-_103265818 0.087 SLC39A8
solute carrier family 39 (zinc transporter), member 8
chr14_-_35344852 0.087 NM_013448
NM_182648
BAZ1A

bromodomain adjacent to zinc finger domain, 1A

chr3_+_127641901 0.087 NM_207335
KBTBD12
kelch repeat and BTB (POZ) domain containing 12
chr13_-_46756295 0.086 LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr21_+_37536838 0.086 NM_005128
DOPEY2
dopey family member 2
chr1_-_116383323 0.086 NM_001111061
NHLH2
nescient helix loop helix 2
chrX_+_107288199 0.085 NM_001170553
NM_182607
VSIG1

V-set and immunoglobulin domain containing 1

chr14_-_69445978 0.085 ACTN1
actinin, alpha 1
chr15_-_43513024 0.085 EPB42
erythrocyte membrane protein band 4.2
chr1_+_199996729 0.085 NM_003822
NM_205860
NR5A2

nuclear receptor subfamily 5, group A, member 2

chr3_-_79817058 0.084 NM_002941
ROBO1
roundabout, axon guidance receptor, homolog 1 (Drosophila)
chr2_+_231578262 0.084 NM_001130849
NM_001130850
CAB39

calcium binding protein 39

chr1_+_15256295 0.084 NM_001018001
KAZN
kazrin, periplakin interacting protein
chr6_-_31088195 0.083 NM_001264
CDSN
corneodesmosin
chr6_-_46047978 0.083 NM_001114086
CLIC5
chloride intracellular channel 5
chr19_+_40146533 0.083 NM_001190441
LGALS16
lectin, galactoside-binding, soluble, 16
chr7_+_127233688 0.083 NM_020369
FSCN3
fascin homolog 3, actin-bundling protein, testicular (Strongylocentrotus purpuratus)
chr18_-_40857245 0.081 NM_020783
SYT4
synaptotagmin IV
chr4_-_122148620 0.081 NM_001244764
TNIP3
TNFAIP3 interacting protein 3
chr7_+_143701021 0.080 NM_001005281
OR6B1
olfactory receptor, family 6, subfamily B, member 1
chr20_-_4990913 0.080 NM_203327
SLC23A2
solute carrier family 23 (nucleobase transporters), member 2
chr17_+_74381186 0.080 NM_001142602
SPHK1
sphingosine kinase 1
chr15_+_48009510 0.079 SEMA6D
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
chrX_+_17653412 0.079 NM_001136024
NHS
Nance-Horan syndrome (congenital cataracts and dental anomalies)
chr1_-_205912546 0.078 NM_052934
NM_134325
SLC26A9

solute carrier family 26, member 9

chr5_-_176935877 0.078 DOK3
docking protein 3
chr17_-_29624249 0.078 NM_002544
OMG
oligodendrocyte myelin glycoprotein
chr20_+_58630965 0.078 NM_173644
C20orf197
chromosome 20 open reading frame 197
chrX_-_55057408 0.077 NM_000032
NM_001037967
NM_001037968
ALAS2


aminolevulinate, delta-, synthase 2


chr1_-_112046742 0.077 NM_000677
NM_020683
ADORA3

adenosine A3 receptor

chr4_-_72649734 0.077 NM_000583
GC
group-specific component (vitamin D binding protein)
chr19_-_13213669 0.076 LYL1
lymphoblastic leukemia derived sequence 1
chr20_+_62795773 0.076 MYT1
myelin transcription factor 1
chr7_-_20256942 0.075 NM_182762
MACC1
metastasis associated in colon cancer 1
chr21_-_39870303 0.075 NM_001136155
NM_182918
ERG

v-ets erythroblastosis virus E26 oncogene homolog (avian)

chr16_+_4475804 0.075 NM_001135110
NM_005147
DNAJA3

DnaJ (Hsp40) homolog, subfamily A, member 3

chr13_-_46756291 0.075 LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr2_+_169757749 0.074 NM_001081686
NM_021176
G6PC2

glucose-6-phosphatase, catalytic, 2

chr20_+_43935490 0.074 NM_014276
RBPJL
recombination signal binding protein for immunoglobulin kappa J region-like
chr2_-_74570533 0.074 NM_133478
SLC4A5
solute carrier family 4, sodium bicarbonate cotransporter, member 5
chr11_+_128563772 0.074 NM_001167681
NM_002017
FLI1

Friend leukemia virus integration 1

chrX_-_119445306 0.074 NM_001104544
NM_001104545
NM_017938
FAM70A


family with sequence similarity 70, member A


chr15_+_49715374 0.074 NM_002009
FGF7
fibroblast growth factor 7

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.30 6.58e-05 GO:0050896 response to stimulus
1.60 8.27e-05 GO:0065008 regulation of biological quality
1.93 3.25e-04 GO:0006629 lipid metabolic process
1.31 6.13e-04 GO:0032501 multicellular organismal process
1.54 8.44e-04 GO:0042221 response to chemical stimulus
2.95 1.61e-03 GO:0008202 steroid metabolic process
2.07 3.58e-02 GO:0001775 cell activation
2.77 4.60e-02 GO:0003013 circulatory system process
2.77 4.60e-02 GO:0008015 blood circulation

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.98 1.05e-14 GO:0005576 extracellular region
2.08 7.41e-08 GO:0044421 extracellular region part
2.07 1.35e-05 GO:0005615 extracellular space
1.35 1.07e-04 GO:0071944 cell periphery
1.35 2.07e-04 GO:0005886 plasma membrane
1.63 1.39e-02 GO:0000267 cell fraction
1.41 1.90e-02 GO:0044459 plasma membrane part

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.87 8.43e-05 GO:0005102 receptor binding
3.51 1.88e-02 GO:0005179 hormone activity
2.81 3.40e-02 GO:0008083 growth factor activity