Motif ID: GCUGGUG

Z-value: 0.932


Mature miRNA associated with seed GCUGGUG:

NamemiRBase Accession
hsa-miR-138 MIMAT0000430



Activity profile for motif GCUGGUG.

activity profile for motif GCUGGUG


Sorted Z-values histogram for motif GCUGGUG

Sorted Z-values for motif GCUGGUG



Network of associatons between targets according to the STRING database.



First level regulatory network of GCUGGUG

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr4_-_2263706 0.621 NM_006454
 MXD4
MAX dimerization protein 4
chr10_-_21463019 0.599 NM_001173484
NM_213569
 NEBL

nebulette

chr10_-_21186530 0.486 NM_006393
 NEBL
nebulette
chr9_-_95896498 0.481 NM_004148
 NINJ1
ninjurin 1
chr6_+_136172802 0.445 NM_018945
 PDE7B
phosphodiesterase 7B
chr10_+_72163860 0.409 NM_004096
 EIF4EBP2
eukaryotic translation initiation factor 4E binding protein 2
chr14_+_52327021 0.392 NM_001243773
NM_001243774
NM_053064
 GNG2


guanine nucleotide binding protein (G protein), gamma 2


chr5_-_158526698 0.382 NM_024007
 EBF1
early B-cell factor 1
chr4_+_52917440 0.378 NM_145263
 SPATA18
spermatogenesis associated 18 homolog (rat)
chr5_+_154238196 0.376 NM_004779
 CNOT8
CCR4-NOT transcription complex, subunit 8
chr9_-_131534186 0.361 NM_006336
 ZER1
zer-1 homolog (C. elegans)
chr11_+_58939539 0.360 NM_015177
 DTX4
deltex homolog 4 (Drosophila)
chr20_+_33292117 0.358 NM_021202
 TP53INP2
tumor protein p53 inducible nuclear protein 2
chr12_-_92539614 0.341 NM_001731
 BTG1
B-cell translocation gene 1, anti-proliferative
chr4_-_78740508 0.332 NM_144571
 CNOT6L
CCR4-NOT transcription complex, subunit 6-like
chr9_-_131940538 0.331 NM_203434
 IER5L
immediate early response 5-like
chr20_+_36531498 0.327 NM_080607
 VSTM2L
V-set and transmembrane domain containing 2 like
chr2_+_113033146 0.323 NM_198581
 ZC3H6
zinc finger CCCH-type containing 6
chrX_-_101397370 0.323 NM_001006938
 TCEAL6
transcription elongation factor A (SII)-like 6
chr17_+_17942584 0.319 NM_024052
 C17orf39
chromosome 17 open reading frame 39

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 23 entries
enrichment   p-value GO term description
2.18 2.24e-02 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
2.14 2.43e-02 GO:0010558 negative regulation of macromolecule biosynthetic process
2.13 4.98e-02 GO:0045893 positive regulation of transcription, DNA-dependent
2.11 2.52e-02 GO:0031327 negative regulation of cellular biosynthetic process
2.07 3.97e-02 GO:0009890 negative regulation of biosynthetic process
1.96 9.00e-03 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.93 3.25e-02 GO:0010605 negative regulation of macromolecule metabolic process
1.59 1.11e-03 GO:0010468 regulation of gene expression
1.57 2.48e-02 GO:0048523 negative regulation of cellular process
1.56 9.37e-03 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.55 4.01e-02 GO:0006355 regulation of transcription, DNA-dependent
1.54 1.41e-04 GO:0060255 regulation of macromolecule metabolic process
1.53 1.62e-02 GO:0010556 regulation of macromolecule biosynthetic process
1.51 2.36e-04 GO:0031323 regulation of cellular metabolic process
1.51 1.42e-02 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.50 5.59e-04 GO:0080090 regulation of primary metabolic process
1.50 1.81e-02 GO:0051171 regulation of nitrogen compound metabolic process
1.50 2.40e-02 GO:0031326 regulation of cellular biosynthetic process
1.48 3.84e-02 GO:0009889 regulation of biosynthetic process
1.47 3.71e-04 GO:0019222 regulation of metabolic process

Gene overrepresentation in compartment category:

Showing 1 to 8 of 8 entries
enrichment   p-value GO term description
6.30 2.67e-02 GO:0000118 histone deacetylase complex
1.37 3.09e-05 GO:0005634 nucleus
1.18 2.04e-06 GO:0005622 intracellular
1.18 6.37e-06 GO:0044424 intracellular part
1.18 4.12e-03 GO:0043229 intracellular organelle
1.17 4.95e-03 GO:0043226 organelle
1.17 3.94e-02 GO:0043231 intracellular membrane-bounded organelle
1.17 4.32e-02 GO:0043227 membrane-bounded organelle

Gene overrepresentation in function category:

Showing 1 to 6 of 6 entries
enrichment   p-value GO term description
4.12 2.84e-04 GO:0003714 transcription corepressor activity
2.28 5.90e-05 GO:0019899 enzyme binding
1.89 4.04e-03 GO:0001071 nucleic acid binding transcription factor activity
1.89 4.04e-03 GO:0003700 sequence-specific DNA binding transcription factor activity
1.31 3.96e-06 GO:0005515 protein binding
1.16 7.35e-05 GO:0005488 binding