Motif ID: GFI1.p2

Z-value: 1.232


Transcription factors associated with GFI1.p2:

Gene SymbolEntrez IDGene Name
GFI1 2672 growth factor independent 1 transcription repressor

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
GFI1chr1_-_92951593-0.724.5e-02Click!


Activity profile for motif GFI1.p2.

activity profile for motif GFI1.p2


Sorted Z-values histogram for motif GFI1.p2

Sorted Z-values for motif GFI1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of GFI1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr6_-_167040700 1.392 NM_021135
 RPS6KA2
ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr6_-_167040659 1.372 RPS6KA2
ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr14_-_92414004 1.233 NM_006329
 FBLN5
fibulin 5
chr6_-_167040506 1.147 RPS6KA2
ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr10_-_93392744 0.953 PPP1R3C
protein phosphatase 1, regulatory subunit 3C
chr10_-_93392857 0.944 NM_005398
 PPP1R3C
protein phosphatase 1, regulatory subunit 3C
chr14_-_61115906 0.931 NM_005982
 SIX1
SIX homeobox 1
chr14_-_60097223 0.867 RTN1
reticulon 1
chr2_-_190044330 0.857 NM_000393
 COL5A2
collagen, type V, alpha 2
chr5_-_172755418 0.849 STC2
stanniocalcin 2
chr14_-_60097314 0.847 RTN1
reticulon 1
chr5_-_172755195 0.813 STC2
stanniocalcin 2
chr17_-_1619473 0.785 MIR22HG
MIR22 host gene (non-protein coding)
chr5_-_19988293 0.777 NM_001167667
NM_004934
 CDH18

cadherin 18, type 2

chrX_+_16964730 0.762 NM_001080975
NM_004726
 REPS2

RALBP1 associated Eps domain containing 2

chr13_-_67804432 0.750 NM_020403
NM_203487
 PCDH9

protocadherin 9

chr2_-_45236521 0.726 NM_016932
 SIX2
SIX homeobox 2
chr11_-_96076328 0.715 NM_032427
 MAML2
mastermind-like 2 (Drosophila)
chr1_-_92351476 0.713 TGFBR3
transforming growth factor, beta receptor III
chr3_+_45927995 0.709 NM_006641
NM_031200
 CCR9

chemokine (C-C motif) receptor 9


Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 60 entries
enrichment   p-value GO term description
2.57 2.18e-03 GO:0065004 protein-DNA complex assembly
2.55 4.91e-02 GO:0045637 regulation of myeloid cell differentiation
2.52 2.44e-03 GO:0071824 protein-DNA complex subunit organization
2.22 2.18e-02 GO:0006333 chromatin assembly or disassembly
2.14 4.34e-06 GO:0000087 M phase of mitotic cell cycle
2.07 1.92e-08 GO:0000279 M phase
2.07 5.31e-05 GO:0000280 nuclear division
2.07 5.31e-05 GO:0007067 mitosis
2.03 7.90e-05 GO:0048285 organelle fission
2.01 1.07e-02 GO:0000075 cell cycle checkpoint
1.97 1.34e-02 GO:0071156 regulation of cell cycle arrest
1.92 2.18e-10 GO:0022403 cell cycle phase
1.91 1.70e-03 GO:0051325 interphase
1.88 9.34e-08 GO:0000278 mitotic cell cycle
1.88 4.53e-03 GO:0051329 interphase of mitotic cell cycle
1.86 1.87e-14 GO:0007049 cell cycle
1.86 9.49e-04 GO:0051301 cell division
1.84 1.40e-03 GO:0034622 cellular macromolecular complex assembly
1.83 3.58e-10 GO:0022402 cell cycle process
1.78 3.52e-06 GO:0051276 chromosome organization

Gene overrepresentation in compartment category:

Showing 1 to 20 of 31 entries
enrichment   p-value GO term description
3.03 5.32e-04 GO:0000922 spindle pole
2.25 1.59e-04 GO:0044454 nuclear chromosome part
2.14 2.24e-05 GO:0000785 chromatin
2.08 1.77e-03 GO:0005819 spindle
2.04 7.10e-04 GO:0000228 nuclear chromosome
2.01 4.50e-09 GO:0044427 chromosomal part
1.98 1.92e-10 GO:0005694 chromosome
1.59 2.20e-04 GO:0015630 microtubule cytoskeleton
1.47 2.77e-06 GO:0005654 nucleoplasm
1.41 1.00e-06 GO:0031981 nuclear lumen
1.39 1.96e-07 GO:0005829 cytosol
1.38 2.34e-07 GO:0044428 nuclear part
1.36 1.17e-23 GO:0005634 nucleus
1.34 1.25e-07 GO:0043228 non-membrane-bounded organelle
1.34 1.25e-07 GO:0043232 intracellular non-membrane-bounded organelle
1.32 1.23e-05 GO:0031974 membrane-enclosed lumen
1.32 3.15e-05 GO:0070013 intracellular organelle lumen
1.32 3.41e-05 GO:0043233 organelle lumen
1.32 6.38e-03 GO:0005856 cytoskeleton
1.24 1.07e-03 GO:0043234 protein complex

Gene overrepresentation in function category:

Showing 1 to 15 of 15 entries
enrichment   p-value GO term description
2.58 2.26e-02 GO:0042393 histone binding
1.98 6.43e-03 GO:0019901 protein kinase binding
1.80 3.68e-02 GO:0019900 kinase binding
1.62 3.84e-02 GO:0003712 transcription cofactor activity
1.62 4.18e-02 GO:0000988 protein binding transcription factor activity
1.62 4.18e-02 GO:0000989 transcription factor binding transcription factor activity
1.57 1.74e-04 GO:0019899 enzyme binding
1.34 4.96e-06 GO:0003677 DNA binding
1.27 9.82e-03 GO:0008270 zinc ion binding
1.25 6.39e-05 GO:0003676 nucleic acid binding
1.22 3.33e-13 GO:0005515 protein binding
1.18 6.57e-03 GO:0043169 cation binding
1.18 6.65e-03 GO:0043167 ion binding
1.18 6.95e-03 GO:0046872 metal ion binding
1.13 2.45e-15 GO:0005488 binding