Motif ID: GGCAAGA

Z-value: 0.307


Mature miRNA associated with seed GGCAAGA:

NamemiRBase Accession
hsa-miR-31 MIMAT0000089



Activity profile for motif GGCAAGA.

activity profile for motif GGCAAGA


Sorted Z-values histogram for motif GGCAAGA

Sorted Z-values for motif GGCAAGA



Network of associatons between targets according to the STRING database.



First level regulatory network of GGCAAGA

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_+_163038564 0.099 NM_005613
RGS4
regulator of G-protein signaling 4
chr1_+_163041694 0.099 NM_001113380
RGS4
regulator of G-protein signaling 4
chr1_+_163038395 0.097 NM_001102445
RGS4
regulator of G-protein signaling 4
chr1_+_163038934 0.096 NM_001113381
RGS4
regulator of G-protein signaling 4
chr5_+_71403040 0.088 NM_005909
MAP1B
microtubule-associated protein 1B
chr2_-_200329810 0.081 NM_001172517
SATB2
SATB homeobox 2
chr2_-_167232464 0.081 NM_002977
SCN9A
sodium channel, voltage-gated, type IX, alpha subunit
chr2_-_200322699 0.079 NM_001172509
SATB2
SATB homeobox 2
chr2_-_200335988 0.078 NM_015265
SATB2
SATB homeobox 2
chr10_-_100027943 0.061 NM_032211
LOXL4
lysyl oxidase-like 4
chr11_+_15136483 0.060 NM_001042536
INSC
inscuteable homolog (Drosophila)
chr11_+_15133969 0.059 NM_001031853
INSC
inscuteable homolog (Drosophila)
chr5_-_9546157 0.047 NM_003966
SEMA5A
sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
chr9_+_120466453 0.045 NM_138554
TLR4
toll-like receptor 4
chr5_+_149340287 0.039 NM_000112
SLC26A2
solute carrier family 26 (sulfate transporter), member 2
chrX_+_73641084 0.036 NM_006517
SLC16A2
solute carrier family 16, member 2 (monocarboxylic acid transporter 8)
chr12_-_49182718 0.035 NM_020983
ADCY6
adenylate cyclase 6
chr7_-_50800018 0.034 NM_001001549
NM_005311
GRB10

growth factor receptor-bound protein 10

chr5_+_172068188 0.033 NM_001142651
NEURL1B
neuralized homolog 1B (Drosophila)
chr7_-_50772997 0.033 NM_001001550
GRB10
growth factor receptor-bound protein 10
chr1_-_92351613 0.033 NM_001195683
NM_003243
TGFBR3

transforming growth factor, beta receptor III

chr7_-_131241321 0.032 NM_001018111
NM_005397
PODXL

podocalyxin-like

chr5_+_156693051 0.030 NM_001037333
NM_001037332
CYFIP2

cytoplasmic FMR1 interacting protein 2

chr13_-_33780142 0.030 NM_001243474
NM_052851
STARD13

StAR-related lipid transfer (START) domain containing 13

chr7_-_50861114 0.029 NM_001001555
GRB10
growth factor receptor-bound protein 10
chr13_-_33760215 0.029 NM_001243466
NM_178007
STARD13

StAR-related lipid transfer (START) domain containing 13

chr13_-_33859835 0.029 NM_178006
STARD13
StAR-related lipid transfer (START) domain containing 13
chr5_+_156696351 0.029 NM_014376
CYFIP2
cytoplasmic FMR1 interacting protein 2
chr20_+_33462765 0.029 NM_001242393
ACSS2
acyl-CoA synthetase short-chain family member 2
chr1_+_145507556 0.027 NM_005105
RBM8A
RNA binding motif protein 8A
chr15_-_52821004 0.027 NM_000259
NM_001142495
MYO5A

myosin VA (heavy chain 12, myoxin)

chr1_-_92371558 0.027 NM_001195684
TGFBR3
transforming growth factor, beta receptor III
chr20_+_33464327 0.026 NM_001076552
NM_018677
ACSS2

acyl-CoA synthetase short-chain family member 2

chr12_-_69326946 0.026 NM_001005502
NM_198320
CPM

carboxypeptidase M

chr5_-_59783885 0.026 NM_001165899
PDE4D
phosphodiesterase 4D, cAMP-specific
chr2_-_175499275 0.025 NM_003387
WIPF1
WAS/WASL interacting protein family, member 1
chr2_-_175547471 0.025 NM_001077269
WIPF1
WAS/WASL interacting protein family, member 1
chr11_+_122526339 0.025 NM_032873
UBASH3B
ubiquitin associated and SH3 domain containing B
chr12_-_69357019 0.025 NM_001874
CPM
carboxypeptidase M
chr5_-_146833150 0.024 NM_001387
DPYSL3
dihydropyrimidinase-like 3
chrX_-_65259839 0.024 NM_001100431
NM_001184830
NM_001184831
NM_007268
VSIG4



V-set and immunoglobulin domain containing 4



chr5_-_64777703 0.024 NM_197941
ADAMTS6
ADAM metallopeptidase with thrombospondin type 1 motif, 6
chr12_-_52585686 0.024 NM_001081492
NM_182507
KRT80

keratin 80

chr5_-_59064437 0.024 NM_001197218
PDE4D
phosphodiesterase 4D, cAMP-specific
chr12_-_49177876 0.023 NM_015270
ADCY6
adenylate cyclase 6
chr10_+_82297657 0.023 NM_207372
SH2D4B
SH2 domain containing 4B
chr10_-_14372807 0.023 NM_018027
FRMD4A
FERM domain containing 4A
chr8_+_77593506 0.022 NM_024721
ZFHX4
zinc finger homeobox 4
chr12_-_42538432 0.022 NM_001099650
NM_173601
GXYLT1

glucoside xylosyltransferase 1

chr14_+_76071804 0.022 NM_001195283
FLVCR2
feline leukemia virus subgroup C cellular receptor family, member 2
chr20_-_8000370 0.022 NM_021156
TMX4
thioredoxin-related transmembrane protein 4
chr22_+_40573879 0.022 NM_001162501
NM_015088
TNRC6B

trinucleotide repeat containing 6B

chr10_+_82300574 0.022 NM_001145719
SH2D4B
SH2 domain containing 4B
chr2_+_102770401 0.021 NM_000877
IL1R1
interleukin 1 receptor, type I
chr3_-_195808958 0.021 NM_003234
TFRC
transferrin receptor (p90, CD71)
chr3_-_98620452 0.021 NM_080927
DCBLD2
discoidin, CUB and LCCL domain containing 2
chr22_+_31090792 0.021 NM_030758
OSBP2
oxysterol binding protein 2
chr12_+_56367696 0.021 NM_001252036
NM_001252037
NM_002868
RAB5B


RAB5B, member RAS oncogene family


chr7_-_139477437 0.021 NM_001113239
NM_022740
HIPK2

homeodomain interacting protein kinase 2

chr19_-_3606801 0.021 NM_001060
NM_201636
TBXA2R

thromboxane A2 receptor

chr5_-_146889618 0.021 NM_001197294
DPYSL3
dihydropyrimidinase-like 3
chr2_-_99552677 0.021 NM_207362
C2orf55
chromosome 2 open reading frame 55
chr10_+_1102741 0.020 NM_014023
WDR37
WD repeat domain 37
chr6_-_30710219 0.020 NM_005803
FLOT1
flotillin 1
chr3_-_195808997 0.020 NM_001128148
TFRC
transferrin receptor (p90, CD71)
chr2_+_204571197 0.020 NM_001243077
NM_001243078
NM_006139
CD28


CD28 molecule


chr5_-_58571916 0.020 NM_001197220
PDE4D
phosphodiesterase 4D, cAMP-specific
chr1_+_199996729 0.020 NM_003822
NM_205860
NR5A2

nuclear receptor subfamily 5, group A, member 2

chr14_+_76044939 0.020 NM_017791
FLVCR2
feline leukemia virus subgroup C cellular receptor family, member 2
chr10_+_124768401 0.020 NM_001609
ACADSB
acyl-CoA dehydrogenase, short/branched chain
chr22_+_40440664 0.019 NM_001024843
TNRC6B
trinucleotide repeat containing 6B
chr3_+_187943192 0.019 NM_001167671
LPP
LIM domain containing preferred translocation partner in lipoma
chr5_-_151066492 0.019 NM_003118
SPARC
secreted protein, acidic, cysteine-rich (osteonectin)
chr10_-_62703822 0.019 NM_001242359
NM_014836
RHOBTB1

Rho-related BTB domain containing 1

chr20_+_56964162 0.019 NM_001195677
NM_004738
VAPB

VAMP (vesicle-associated membrane protein)-associated protein B and C

chr8_+_38585703 0.019 NM_001146216
TACC1
transforming, acidic coiled-coil containing protein 1
chr5_-_59189620 0.019 NM_001104631
PDE4D
phosphodiesterase 4D, cAMP-specific
chr15_+_52043738 0.019 NM_001142885
NM_014548
TMOD2

tropomodulin 2 (neuronal)

chr8_-_95907423 0.019 NM_057749
CCNE2
cyclin E2
chr1_-_214724974 0.018 NM_005401
PTPN14
protein tyrosine phosphatase, non-receptor type 14
chr15_-_99789585 0.018 NM_001040655
NM_001040656
NM_001040657
NM_001040658
NM_001040659
NM_001040660
NM_022905
TTC23






tetratricopeptide repeat domain 23






chr11_-_35441099 0.018 NM_004171
SLC1A2
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr10_-_129924467 0.018 NM_001145966
NM_002417
MKI67

antigen identified by monoclonal antibody Ki-67

chr21_-_45079327 0.017 NM_007031
HSF2BP
heat shock transcription factor 2 binding protein
chrX_-_103087106 0.017 NM_016370
RAB9B
RAB9B, member RAS oncogene family
chr2_+_27309610 0.017 NM_000221
NM_006488
KHK

ketohexokinase (fructokinase)

chr1_+_78354199 0.017 NM_001172309
NM_144573
NEXN

nexilin (F actin binding protein)

chr18_-_57364643 0.017 NM_133459
CCBE1
collagen and calcium binding EGF domains 1
chr14_+_75229995 0.017 NM_019589
YLPM1
YLP motif containing 1
chr8_+_70405027 0.017 NM_001128205
NM_001128206
SULF1

sulfatase 1

chr5_-_58652671 0.017 NM_001197219
PDE4D
phosphodiesterase 4D, cAMP-specific
chr5_+_60628085 0.017 NM_020928
ZSWIM6
zinc finger, SWIM-type containing 6
chr5_-_180230047 0.017 NM_002406
MGAT1
mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
chr4_+_184020343 0.016 NM_024949
WWC2
WW and C2 domain containing 2
chr5_-_58334936 0.016 NM_001197221
NM_001197222
PDE4D

phosphodiesterase 4D, cAMP-specific

chr1_+_27022521 0.016 NM_006015
NM_139135
ARID1A

AT rich interactive domain 1A (SWI-like)

chrX_-_151143096 0.016 NM_004961
GABRE
gamma-aminobutyric acid (GABA) A receptor, epsilon
chr16_+_70613797 0.016 NM_001172771
NM_152456
IL34

interleukin 34

chr1_-_154842725 0.016 NM_001204087
NM_002249
KCNN3

potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3

chr3_-_57199402 0.016 NM_017563
IL17RD
interleukin 17 receptor D
chr8_+_38644721 0.016 NM_001122824
NM_006283
TACC1

transforming, acidic coiled-coil containing protein 1

chr20_-_39928708 0.016 NM_015035
ZHX3
zinc fingers and homeoboxes 3
chr5_+_140767402 0.016 NM_003736
NM_032098
PCDHGB4

protocadherin gamma subfamily B, 4

chr5_-_58882274 0.016 NM_006203
PDE4D
phosphodiesterase 4D, cAMP-specific
chr4_-_76928601 0.016 NM_002416
CXCL9
chemokine (C-X-C motif) ligand 9
chr5_+_140792507 0.015 NM_018913
NM_032090
PCDHGA10

protocadherin gamma subfamily A, 10

chr7_-_100286869 0.015 NM_022574
GIGYF1
GRB10 interacting GYF protein 1
chr1_+_151170978 0.015 NM_001135636
NM_001135637
NM_001135638
NM_003557
PIP5K1A



phosphatidylinositol-4-phosphate 5-kinase, type I, alpha



chr3_+_187930720 0.015 NM_005578
LPP
LIM domain containing preferred translocation partner in lipoma
chr9_+_125133228 0.015 NM_000962
NM_080591
PTGS1

prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)

chr14_+_90863302 0.015 NM_006888
CALM1
calmodulin 1 (phosphorylase kinase, delta)
chr11_-_35441501 0.015 NM_001195728
NM_001252652
SLC1A2

solute carrier family 1 (glial high affinity glutamate transporter), member 2

chr5_+_139927182 0.015 NM_003732
EIF4EBP3
eukaryotic translation initiation factor 4E binding protein 3
chr16_+_4902076 0.014 NM_016936
UBN1
ubinuclein 1
chr2_-_218808705 0.014 NM_022648
TNS1
tensin 1
chr15_-_58358120 0.014 NM_001206897
NM_003888
NM_170696
ALDH1A2


aldehyde dehydrogenase 1 family, member A2


chr5_+_140743755 0.014 NM_018918
NM_032054
PCDHGA5

protocadherin gamma subfamily A, 5

chr5_-_180230889 0.014 NM_001114619
NM_001114620
MGAT1

mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase

chr3_+_191046873 0.014 NM_174908
NM_178335
CCDC50

coiled-coil domain containing 50

chr11_-_17191287 0.014 NM_002645
PIK3C2A
phosphoinositide-3-kinase, class 2, alpha polypeptide
chr8_+_70378858 0.014 NM_001128204
NM_015170
SULF1

sulfatase 1

chr16_+_69220940 0.013 NM_006750
SNTB2
syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2)
chr8_+_143808593 0.013 NM_016647
C8orf55
chromosome 8 open reading frame 55
chr16_+_70657894 0.013 NM_001172772
IL34
interleukin 34
chr1_+_203444882 0.013 NM_002725
NM_201348
PRELP

proline/arginine-rich end leucine-rich repeat protein

chr3_+_132757170 0.013 NM_001136469
NM_023943
TMEM108

transmembrane protein 108

chr16_+_4897911 0.013 NM_001079514
UBN1
ubinuclein 1
chr5_+_140753480 0.013 NM_018919
NM_032086
PCDHGA6

protocadherin gamma subfamily A, 6

chr3_+_5021096 0.013 NM_003670
BHLHE40
basic helix-loop-helix family, member e40
chr3_-_133614421 0.013 NM_016577
RAB6B
RAB6B, member RAS oncogene family
chr20_+_30697291 0.013 NM_014742
TM9SF4
transmembrane 9 superfamily protein member 4
chr20_+_43595119 0.013 NM_006282
STK4
serine/threonine kinase 4
chr1_-_23857711 0.013 NM_004091
E2F2
E2F transcription factor 2
chr15_+_63481713 0.013 NM_016530
RAB8B
RAB8B, member RAS oncogene family
chr6_+_131456825 0.013 NM_016377
AKAP7
A kinase (PRKA) anchor protein 7
chrX_-_53310748 0.012 NM_001243197
NM_015075
IQSEC2

IQ motif and Sec7 domain 2

chr5_-_90679115 0.012 NM_020801
ARRDC3
arrestin domain containing 3
chr14_+_95047730 0.012 NM_000624
SERPINA5
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
chr4_+_140222668 0.012 NM_057175
NAA15
N(alpha)-acetyltransferase 15, NatA auxiliary subunit
chr8_+_22457098 0.012 NM_001013842
NM_001198827
NM_173686
C8orf58


chromosome 8 open reading frame 58


chr6_+_158438079 0.012 NM_001178088
SYNJ2
synaptojanin 2
chr10_+_18689512 0.012 NM_201570
CACNB2
calcium channel, voltage-dependent, beta 2 subunit
chr19_-_8070468 0.012 NM_001419
ELAVL1
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)
chr1_-_47695442 0.012 NM_003189
TAL1
T-cell acute lymphocytic leukemia 1
chr2_-_100939194 0.012 NM_198461
LONRF2
LON peptidase N-terminal domain and ring finger 2
chr1_-_151804225 0.012 NM_005060
RORC
RAR-related orphan receptor C
chr14_-_21852424 0.012 NM_007192
SUPT16H
suppressor of Ty 16 homolog (S. cerevisiae)
chr12_-_54653317 0.012 NM_001127322
CBX5
chromobox homolog 5
chr17_-_46035109 0.012 NM_024320
PRR15L
proline rich 15-like
chr15_-_56209305 0.011 NM_198400
NEDD4
neural precursor cell expressed, developmentally down-regulated 4
chr17_+_44668034 0.011 NM_006178
NSF
N-ethylmaleimide-sensitive factor
chr10_+_101088794 0.011 NM_020348
CNNM1
cyclin M1
chr3_-_56502364 0.011 NM_015576
ERC2
ELKS/RAB6-interacting/CAST family member 2
chr16_+_30406711 0.011 NM_152652
ZNF48
zinc finger protein 48
chr5_-_180236816 0.011 NM_001114618
MGAT1
mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
chr9_-_72374855 0.011 NM_001099666
PTAR1
protein prenyltransferase alpha subunit repeat containing 1
chr1_-_208417635 0.011 NM_025179
PLXNA2
plexin A2
chr22_+_45704821 0.011 NM_001104595
FAM118A
family with sequence similarity 118, member A
chr19_-_11308184 0.011 NM_001136191
KANK2
KN motif and ankyrin repeat domains 2
chr7_+_100797685 0.011 NM_001283
AP1S1
adaptor-related protein complex 1, sigma 1 subunit
chr12_-_54653369 0.011 NM_001127321
CBX5
chromobox homolog 5
chr2_+_121554866 0.011 NM_005270
GLI2
GLI family zinc finger 2
chr6_-_168720389 0.011 NM_214462
DACT2
dapper, antagonist of beta-catenin, homolog 2 (Xenopus laevis)
chrX_-_53350521 0.011 NM_001111125
IQSEC2
IQ motif and Sec7 domain 2
chr5_-_58295758 0.011 NM_001197223
PDE4D
phosphodiesterase 4D, cAMP-specific
chr5_-_114880536 0.011 NM_020177
FEM1C
fem-1 homolog c (C. elegans)
chr9_-_20622476 0.011 NM_004529
MLLT3
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
chr8_+_27183062 0.011 NM_173175
PTK2B
PTK2B protein tyrosine kinase 2 beta
chr11_-_118661898 0.011 NM_004397
DDX6
DEAD (Asp-Glu-Ala-Asp) box polypeptide 6
chr2_-_44586854 0.011 NM_001042385
NM_001042386
PREPL

prolyl endopeptidase-like

chr16_+_58283819 0.011 NM_001142302
NM_014157
CCDC113

coiled-coil domain containing 113

chr3_+_187871473 0.011 NM_001167672
LPP
LIM domain containing preferred translocation partner in lipoma
chr10_+_18629613 0.010 NM_201590
CACNB2
calcium channel, voltage-dependent, beta 2 subunit
chr5_-_180237114 0.010 NM_001114617
MGAT1
mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
chr6_+_158402887 0.010 NM_003898
SYNJ2
synaptojanin 2
chr15_-_58306185 0.010 NM_170697
ALDH1A2
aldehyde dehydrogenase 1 family, member A2
chr16_+_70557688 0.010 NM_012426
SF3B3
splicing factor 3b, subunit 3, 130kDa
chr16_-_4897265 0.010 NM_032569
GLYR1
glyoxylate reductase 1 homolog (Arabidopsis)
chr16_+_30389632 0.010 NM_001214906
NM_001214907
ZNF48

zinc finger protein 48

chr19_-_11305186 0.010 NM_015493
KANK2
KN motif and ankyrin repeat domains 2
chr2_-_158485393 0.010 NM_001111032
NM_001111033
NM_145259
ACVR1C


activin A receptor, type IC


chr1_-_154832187 0.010 NM_170782
KCNN3
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3
chr16_+_89724175 0.010 NM_153025
C16orf55
chromosome 16 open reading frame 55
chr5_+_140729723 0.010 NM_018922
NM_032095
PCDHGB1

protocadherin gamma subfamily B, 1

chr2_+_27805892 0.010 NM_032434
ZNF512
zinc finger protein 512
chr1_+_154975041 0.010 NM_001252405
NM_015872
ZBTB7B

zinc finger and BTB domain containing 7B

chr10_-_94333847 0.010 NM_004969
IDE
insulin-degrading enzyme
chr8_+_27182995 0.010 NM_173176
PTK2B
PTK2B protein tyrosine kinase 2 beta
chr17_+_64960754 0.010 NM_014405
CACNG4
calcium channel, voltage-dependent, gamma subunit 4
chr5_+_140810126 0.010 NM_003735
NM_032094
PCDHGA12

protocadherin gamma subfamily A, 12

chr6_-_116575170 0.010 NM_021648
TSPYL4
TSPY-like 4
chr4_+_87856152 0.010 NM_001166693
AFF1
AF4/FMR2 family, member 1
chr8_-_18666295 0.010 NM_206909
PSD3
pleckstrin and Sec7 domain containing 3
chr3_+_195943382 0.010 NM_152672
OSTalpha
organic solute transporter alpha
chr10_+_128593994 0.010 NM_001380
DOCK1
dedicator of cytokinesis 1
chr5_+_140777603 0.010 NM_018925
NM_032099
PCDHGB5

protocadherin gamma subfamily B, 5

chr11_-_110167191 0.009 NM_002906
RDX
radixin
chr12_-_54813010 0.009 NM_002205
ITGA5
integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
chr19_+_15218141 0.009 NM_033025
SYDE1
synapse defective 1, Rho GTPase, homolog 1 (C. elegans)
chr5_+_140739589 0.009 NM_018923
NM_032096
PCDHGB2

protocadherin gamma subfamily B, 2


Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
4.24 8.57e-04 GO:0007156 homophilic cell adhesion
1.99 9.98e-03 GO:0015031 protein transport
1.96 1.60e-02 GO:0045184 establishment of protein localization
1.80 4.61e-02 GO:0008104 protein localization

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.07 3.47e-02 GO:0044464 cell part
1.07 3.52e-02 GO:0005623 cell
2.92 3.72e-02 GO:0031252 cell leading edge

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.12 3.61e-02 GO:0005488 binding