Motif ID: GTF2A1,2.p2

Z-value: 0.921


Transcription factors associated with GTF2A1,2.p2:

Gene SymbolEntrez IDGene Name
GTF2A1 2957 general transcription factor IIA, 1, 19/37kDa
GTF2A2 2958 general transcription factor IIA, 2, 12kDa

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
GTF2A2chr15_-_599495360.676.9e-02Click!
GTF2A1chr14_-_81687265,
chr14_-_81687574		0.314.5e-01Click!


Activity profile for motif GTF2A1,2.p2.

activity profile for motif GTF2A1,2.p2


Sorted Z-values histogram for motif GTF2A1,2.p2

Sorted Z-values for motif GTF2A1,2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of GTF2A1,2.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr1_+_203274646 0.742 NM_006763
 BTG2
BTG family, member 2
chr17_+_17206626 0.350 NM_020201
 NT5M
5',3'-nucleotidase, mitochondrial
chr11_+_5653484 0.324 NM_130390
 TRIM34
tripartite motif containing 34
chr19_+_56153417 0.318 NM_016202
NM_001163423
 ZNF580

zinc finger protein 580

chr19_+_49468656 0.279 FTL
ferritin, light polypeptide
chr6_-_42713783 0.274 TBCC
tubulin folding cofactor C
chr12_-_7245048 0.265 C1R
complement component 1, r subcomponent
chr19_+_49468587 0.259 FTL
ferritin, light polypeptide
chrX_-_106960268 0.258 NM_004089
 TSC22D3
TSC22 domain family, member 3
chr8_+_70378858 0.258 NM_001128204
NM_015170
 SULF1

sulfatase 1

chr19_+_49468557 0.257 NM_000146
 FTL
ferritin, light polypeptide
chr10_-_103543156 0.252 NM_006993
 NPM3
nucleophosmin/nucleoplasmin 3
chr10_-_103543148 0.248 NPM3
nucleophosmin/nucleoplasmin 3
chr2_+_30369800 0.244 YPEL5
yippee-like 5 (Drosophila)
chr2_+_30369749 0.241 NM_001127399
NM_001127400
NM_001127401
NM_016061
 YPEL5



yippee-like 5 (Drosophila)



chr12_-_7245006 0.234 NM_001733
 C1R
complement component 1, r subcomponent
chr16_-_4562979 0.232 C16orf5
chromosome 16 open reading frame 5
chr2_+_95537177 0.230 NM_144705
 TEKT4
tektin 4
chr10_+_101542460 0.229 NM_000392
 ABCC2
ATP-binding cassette, sub-family C (CFTR/MRP), member 2
chr17_-_39183453 0.228 NM_031957
 KRTAP1-5
keratin associated protein 1-5

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 7 of 7 entries
enrichment   p-value GO term description
10.42 2.14e-02 GO:0042989 sequestering of actin monomers
3.63 1.45e-02 GO:0031333 negative regulation of protein complex assembly
3.13 1.98e-02 GO:0051494 negative regulation of cytoskeleton organization
1.89 2.14e-02 GO:0030029 actin filament-based process
1.48 3.02e-02 GO:0006351 transcription, DNA-dependent
1.45 2.88e-02 GO:0032774 RNA biosynthetic process
1.09 1.74e-04 GO:0009987 cellular process

Gene overrepresentation in compartment category:

Showing 1 to 5 of 5 entries
enrichment   p-value GO term description
1.36 1.79e-05 GO:0005829 cytosol
1.18 2.46e-02 GO:0032991 macromolecular complex
1.15 3.16e-03 GO:0005634 nucleus
1.08 1.88e-05 GO:0005622 intracellular
1.08 1.46e-04 GO:0044424 intracellular part

Gene overrepresentation in function category:

Showing 1 to 4 of 4 entries
enrichment   p-value GO term description
1.41 1.92e-02 GO:0001071 nucleic acid binding transcription factor activity
1.41 1.92e-02 GO:0003700 sequence-specific DNA binding transcription factor activity
1.18 1.61e-08 GO:0005515 protein binding
1.09 1.07e-06 GO:0005488 binding