Motif ID: GUAACAG

Z-value: 0.380


Mature miRNA associated with seed GUAACAG:

NamemiRBase Accession
hsa-miR-194 MIMAT0000460



Activity profile for motif GUAACAG.

activity profile for motif GUAACAG


Sorted Z-values histogram for motif GUAACAG

Sorted Z-values for motif GUAACAG



Network of associatons between targets according to the STRING database.



First level regulatory network of GUAACAG

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr16_+_22825806 0.446 NM_006043
HS3ST2
heparan sulfate (glucosamine) 3-O-sulfotransferase 2
chr8_+_102504661 0.389 NM_024915
GRHL2
grainyhead-like 2 (Drosophila)
chr5_-_139726173 0.367 NM_001945
HBEGF
heparin-binding EGF-like growth factor
chr1_+_82266081 0.346 NM_012302
LPHN2
latrophilin 2
chr11_+_69924407 0.265 NM_018043
ANO1
anoctamin 1, calcium activated chloride channel
chr4_+_1795004 0.233 NM_000142
NM_001163213
NM_022965
FGFR3


fibroblast growth factor receptor 3


chr16_-_87903028 0.232 NM_003486
SLC7A5
solute carrier family 7 (amino acid transporter light chain, L system), member 5
chr9_-_124984018 0.222 NM_001242335
LHX6
LIM homeobox 6
chr9_-_33447527 0.209 NM_004925
AQP3
aquaporin 3 (Gill blood group)
chr9_-_124990706 0.190 NM_001242333
LHX6
LIM homeobox 6
chr4_+_95679075 0.180 NM_001203
BMPR1B
bone morphogenetic protein receptor, type IB
chr12_+_72666462 0.178 NM_013381
TRHDE
thyrotropin-releasing hormone degrading enzyme
chr9_-_124990949 0.171 NM_014368
NM_199160
LHX6

LIM homeobox 6

chr7_+_145813452 0.154 NM_014141
CNTNAP2
contactin associated protein-like 2
chr7_-_139876718 0.144 NM_030647
JHDM1D
jumonji C domain containing histone demethylase 1 homolog D (S. cerevisiae)
chr11_-_115375065 0.136 NM_001098517
NM_014333
CADM1

cell adhesion molecule 1

chr12_-_123594974 0.126 NM_020845
PITPNM2
phosphatidylinositol transfer protein, membrane-associated 2
chr14_-_38064440 0.125 NM_004496
FOXA1
forkhead box A1
chr9_-_124989755 0.125 NM_001242334
LHX6
LIM homeobox 6
chr3_+_36421944 0.123 NM_003149
STAC
SH3 and cysteine rich domain

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 23 entries
enrichment   p-value GO term description
4.87 4.91e-02 GO:0048511 rhythmic process
2.76 1.44e-04 GO:0006357 regulation of transcription from RNA polymerase II promoter
2.75 3.48e-02 GO:0045893 positive regulation of transcription, DNA-dependent
2.63 1.94e-02 GO:0010557 positive regulation of macromolecule biosynthetic process
2.43 4.61e-02 GO:0031328 positive regulation of cellular biosynthetic process
2.09 2.51e-02 GO:0009966 regulation of signal transduction
2.07 7.70e-03 GO:0023051 regulation of signaling
1.96 1.05e-02 GO:0048513 organ development
1.92 2.04e-02 GO:0048583 regulation of response to stimulus
1.87 3.45e-03 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.84 1.90e-02 GO:0006355 regulation of transcription, DNA-dependent
1.82 7.65e-03 GO:0010556 regulation of macromolecule biosynthetic process
1.75 4.24e-02 GO:0048522 positive regulation of cellular process
1.72 3.14e-02 GO:0031326 regulation of cellular biosynthetic process
1.70 4.32e-02 GO:0009889 regulation of biosynthetic process
1.64 1.94e-02 GO:0060255 regulation of macromolecule metabolic process
1.58 2.93e-02 GO:0023052 signaling
1.58 4.71e-02 GO:0031323 regulation of cellular metabolic process
1.56 4.63e-02 GO:0032502 developmental process
1.42 1.11e-03 GO:0050794 regulation of cellular process

Gene overrepresentation in compartment category:

Showing 1 to 7 of 7 entries
enrichment   p-value GO term description
1.47 7.60e-04 GO:0005634 nucleus
1.29 2.47e-03 GO:0043231 intracellular membrane-bounded organelle
1.29 2.65e-03 GO:0043227 membrane-bounded organelle
1.26 1.57e-03 GO:0043229 intracellular organelle
1.26 1.79e-03 GO:0043226 organelle
1.21 1.38e-03 GO:0005622 intracellular
1.20 4.19e-03 GO:0044424 intracellular part

Gene overrepresentation in function category:

Showing 1 to 7 of 7 entries
enrichment   p-value GO term description
22.60 5.36e-03 GO:0032452 histone demethylase activity
16.32 2.18e-02 GO:0032451 demethylase activity
3.88 8.49e-03 GO:0003702 RNA polymerase II transcription factor activity
2.30 6.71e-03 GO:0001071 nucleic acid binding transcription factor activity
2.30 6.71e-03 GO:0003700 sequence-specific DNA binding transcription factor activity
2.24 1.05e-02 GO:0030528 transcription regulator activity
1.72 1.63e-02 GO:0003677 DNA binding