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• Mean activities

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• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)
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Motif ID: HES1.p2

Z-value: 1.538

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr1_-_201368434	0.872		LAD1	ladinin 1
chr18_+_33877630	0.668	NM_025135	FHOD3	formin homology 2 domain containing 3
chr1_-_94374986	0.626	NM_002061	GCLM	glutamate-cysteine ligase, modifier subunit
chr22_+_45098091	0.620	NM_181334	PRR5-ARHGAP8 PRR5	PRR5-ARHGAP8 readthrough proline rich 5 (renal)
chr21_-_46962281	0.594	NM_001205206 NM_194255	SLC19A1	solute carrier family 19 (folate transporter), member 1
chr10_-_14646237	0.575		FAM107B	family with sequence similarity 107, member B
chr19_+_39833132	0.573		SAMD4B	sterile alpha motif domain containing 4B
chr1_+_234040547	0.568	NM_173508	SLC35F3	solute carrier family 35, member F3
chr2_-_96811138	0.555	NM_004418	DUSP2	dual specificity phosphatase 2
chr1_-_33430285	0.544	NM_001127361 NM_153341	RNF19B	ring finger protein 19B
chr8_+_31497267	0.544	NM_013962	NRG1	neuregulin 1
chr1_-_231175971	0.539	NM_198552	FAM89A	family with sequence similarity 89, member A
chr7_-_44365019	0.532	NM_001220 NM_172078 NM_172079 NM_172080 NM_172081 NM_172082 NM_172083 NM_172084	CAMK2B	calcium/calmodulin-dependent protein kinase II beta
chr16_+_577833	0.526	NM_005632	SOLH	small optic lobes homolog (Drosophila)
chr5_+_149737296	0.498		TCOF1	Treacher Collins-Franceschetti syndrome 1
chr16_+_30194730	0.490	NM_001193333 NM_007074	CORO1A	coronin, actin binding protein, 1A
chr1_-_201368617	0.485	NM_005558	LAD1	ladinin 1
chr2_-_38604380	0.480		ATL2	atlastin GTPase 2
chr16_-_85784628	0.480	NM_206967	C16orf74	chromosome 16 open reading frame 74
chr9_-_126030792	0.477	NM_018387	STRBP	spermatid perinuclear RNA binding protein
chr2_-_38604430	0.477	NM_001135673 NM_022374	ATL2	atlastin GTPase 2
chr17_+_74380676	0.473	NM_001142601 NM_021972 NM_182965	SPHK1	sphingosine kinase 1
chr5_+_612404	0.471	NM_018140	CEP72	centrosomal protein 72kDa
chr19_+_1524072	0.467	NM_001243079	PLK5	polo-like kinase 5
chr5_+_149737201	0.456	NM_000356 NM_001008657 NM_001135243 NM_001135244 NM_001135245 NM_001195141	TCOF1	Treacher Collins-Franceschetti syndrome 1
chr6_-_105627857	0.454	NM_022361	POPDC3	popeye domain containing 3
chr5_+_612454	0.452		CEP72	centrosomal protein 72kDa
chr1_-_94375028	0.448		GCLM	glutamate-cysteine ligase, modifier subunit
chr1_-_201368716	0.444		LAD1	ladinin 1
chr8_+_61591239	0.443	NM_017780	CHD7	chromodomain helicase DNA binding protein 7
chr6_+_43738757	0.441		VEGFA	vascular endothelial growth factor A
chr11_+_124933197	0.433		SLC37A2	solute carrier family 37 (glycerol-3-phosphate transporter), member 2
chr8_+_95653340	0.432	NM_001034915 NM_001122825 NM_001122826 NM_001122827 NM_017697	ESRP1	epithelial splicing regulatory protein 1
chr2_+_106361404	0.428	NM_001004722 NM_003581	NCK2	NCK adaptor protein 2
chr8_-_105601124	0.421		LRP12	low density lipoprotein receptor-related protein 12
chr1_-_94374949	0.418		GCLM	glutamate-cysteine ligase, modifier subunit
chr7_+_26242007	0.418
chr16_-_87903028	0.417	NM_003486	SLC7A5	solute carrier family 7 (amino acid transporter light chain, L system), member 5
chr8_+_95653399	0.414		ESRP1	epithelial splicing regulatory protein 1
chr16_+_22825806	0.412	NM_006043	HS3ST2	heparan sulfate (glucosamine) 3-O-sulfotransferase 2
chr1_-_38273852	0.409	NM_024640	YRDC	yrdC domain containing (E. coli)
chr1_+_15250578	0.409	NM_001018000	KAZN	kazrin, periplakin interacting protein
chr19_+_35739838	0.402		LSR	lipolysis stimulated lipoprotein receptor
chrX_-_9733916	0.396	NM_000273	GPR143	G protein-coupled receptor 143
chr20_+_6748744	0.396	NM_001200	BMP2	bone morphogenetic protein 2
chr9_+_101867401	0.393	NM_001130916 NM_004612	TGFBR1	transforming growth factor, beta receptor 1
chr17_-_76124767	0.392		TMC6	transmembrane channel-like 6
chr7_+_155089614	0.375		INSIG1	insulin induced gene 1
chr14_-_77279242	0.369	NM_015305	ANGEL1	angel homolog 1 (Drosophila)
chr13_-_99229037	0.367		STK24	serine/threonine kinase 24
chr7_-_139876718	0.367	NM_030647	JHDM1D	jumonji C domain containing histone demethylase 1 homolog D (S. cerevisiae)
chr17_-_3599298	0.367		P2RX5	purinergic receptor P2X, ligand-gated ion channel, 5
chr9_+_101867392	0.361		TGFBR1	transforming growth factor, beta receptor 1
chr20_+_58152563	0.357	NM_001199505	PHACTR3	phosphatase and actin regulator 3
chr8_+_28351694	0.356	NM_017412 NM_145866	FZD3	frizzled family receptor 3
chr4_-_4291817	0.353		LYAR	Ly1 antibody reactive homolog (mouse)
chr9_-_139137646	0.352	NM_181701	QSOX2	quiescin Q6 sulfhydryl oxidase 2
chr2_-_62733475	0.352	NM_198276	TMEM17	transmembrane protein 17
chr14_-_53162418	0.350	NM_014584	ERO1L	ERO1-like (S. cerevisiae)
chr19_+_34287662	0.349	NM_001129994 NM_001129995 NM_024076	KCTD15	potassium channel tetramerisation domain containing 15
chr10_-_71905947	0.348		TYSND1	trypsin domain containing 1
chr9_-_126030854	0.348	NM_001171137	STRBP	spermatid perinuclear RNA binding protein
chr1_+_23345985	0.344		KDM1A	lysine (K)-specific demethylase 1A
chr8_+_61591358	0.344		CHD7	chromodomain helicase DNA binding protein 7
chr17_-_3599359	0.343		P2RX5	purinergic receptor P2X, ligand-gated ion channel, 5
chrX_+_105969875	0.342	NM_194463	RNF128	ring finger protein 128
chr2_+_47596286	0.341	NM_002354	EPCAM	epithelial cell adhesion molecule
chr8_-_141645603	0.339	NM_001164623 NM_012154	EIF2C2	eukaryotic translation initiation factor 2C, 2
chr17_+_55162530	0.337	NM_003488	AKAP1	A kinase (PRKA) anchor protein 1
chr1_-_38273846	0.334		YRDC	yrdC domain containing (E. coli)
chr7_-_994259	0.333	NM_006869	ADAP1	ArfGAP with dual PH domains 1
chr4_+_1795004	0.331	NM_000142 NM_001163213 NM_022965	FGFR3	fibroblast growth factor receptor 3
chr2_-_75937707	0.330	NM_001201334	GCFC2	GC-rich sequence DNA-binding factor 2
chr18_+_47088400	0.327	NM_006033	LIPG	lipase, endothelial
chr1_-_53793583	0.326		LRP8	low density lipoprotein receptor-related protein 8, apolipoprotein e receptor
chr4_-_4291889	0.324	NM_017816	LYAR	Ly1 antibody reactive homolog (mouse)
chr17_+_30813928	0.321	NM_003885	CDK5R1	cyclin-dependent kinase 5, regulatory subunit 1 (p35)
chr1_+_23345928	0.318	NM_001009999 NM_015013	KDM1A	lysine (K)-specific demethylase 1A
chr11_+_124933007	0.316	NM_001145290 NM_198277	SLC37A2	solute carrier family 37 (glycerol-3-phosphate transporter), member 2
chr17_+_1633754	0.315		WDR81	WD repeat domain 81
chr3_-_52090090	0.314	NM_001947	DUSP7	dual specificity phosphatase 7
chr18_-_77793914	0.313
chr14_+_105886146	0.312	NM_001203258 NM_004689	MTA1	metastasis associated 1
chr12_+_122459791	0.311	NM_001024808 NM_020993	BCL7A	B-cell CLL/lymphoma 7A
chr5_-_6633149	0.311		NSUN2	NOP2/Sun domain family, member 2
chr17_-_56565700	0.311	NM_001080439	HSF5	heat shock transcription factor family member 5
chr19_+_35739778	0.309		LSR	lipolysis stimulated lipoprotein receptor
chr1_+_165797060	0.308		UCK2	uridine-cytidine kinase 2
chr1_-_53793743	0.306	NM_001018054 NM_004631 NM_017522 NM_033300	LRP8	low density lipoprotein receptor-related protein 8, apolipoprotein e receptor
chr2_-_101925051	0.293	NM_173647	RNF149	ring finger protein 149
chr3_-_57113292	0.293	NM_001128615	ARHGEF3	Rho guanine nucleotide exchange factor (GEF) 3
chr6_+_37137882	0.292	NM_001243186 NM_002648	PIM1	pim-1 oncogene
chr17_+_74380943	0.292		SPHK1	sphingosine kinase 1
chr21_+_45209398	0.291	NM_003683	RRP1	ribosomal RNA processing 1 homolog (S. cerevisiae)
chr2_+_75061234	0.290		HK2	hexokinase 2
chr17_-_8022134	0.290	NM_001165960	ALOXE3	arachidonate lipoxygenase 3
chr17_-_2614926	0.287	NM_015229	KIAA0664	KIAA0664
chr11_+_68079999	0.285	NM_002335	LRP5	low density lipoprotein receptor-related protein 5
chr22_+_32340435	0.285	NM_003405	YWHAH	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide
chr8_+_87526666	0.284		CPNE3	copine III
chr19_-_39340362	0.282		HNRNPL	heterogeneous nuclear ribonucleoprotein L
chr12_+_132413776	0.277	NM_001002019 NM_025215	PUS1	pseudouridylate synthase 1
chr16_+_610393	0.276	NM_145270	C16orf11	chromosome 16 open reading frame 11
chr6_-_105850765	0.275		PREP	prolyl endopeptidase
chr16_-_3030391	0.272		PKMYT1	protein kinase, membrane associated tyrosine/threonine 1
chr3_-_47823419	0.272		SMARCC1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1
chr19_+_35739519	0.272	NM_015925 NM_205834 NM_205835	LSR	lipolysis stimulated lipoprotein receptor
chr14_-_100070442	0.272	NM_001144995	CCDC85C	coiled-coil domain containing 85C
chr8_+_87526646	0.270	NM_003909	CPNE3	copine III
chr17_-_8027396	0.268	NM_001165967 NM_032580	HES7	hairy and enhancer of split 7 (Drosophila)
chr18_-_12377168	0.268		AFG3L2	AFG3 ATPase family gene 3-like 2 (S. cerevisiae)
chr13_-_99229117	0.267		STK24	serine/threonine kinase 24
chr14_-_53162198	0.266		ERO1L	ERO1-like (S. cerevisiae)
chr16_-_3030473	0.265	NM_004203 NM_182687	PKMYT1	protein kinase, membrane associated tyrosine/threonine 1
chr15_-_26108236	0.265	NM_024490	ATP10A	ATPase, class V, type 10A
chr4_+_57774365	0.264		REST	RE1-silencing transcription factor
chr2_+_131674223	0.263	NM_015320 NM_032995	ARHGEF4	Rho guanine nucleotide exchange factor (GEF) 4
chr1_-_175161832	0.262	NM_001162895 NM_014656 NM_001162893 NM_001162894	KIAA0040	KIAA0040
chr7_-_98030165	0.261		BAIAP2L1	BAI1-associated protein 2-like 1
chr8_-_105601234	0.260	NM_001135703 NM_013437	LRP12	low density lipoprotein receptor-related protein 12
chr16_+_22825481	0.259		HS3ST2	heparan sulfate (glucosamine) 3-O-sulfotransferase 2
chr17_+_74381186	0.259	NM_001142602	SPHK1	sphingosine kinase 1
chr14_-_23834417	0.258		EFS	embryonal Fyn-associated substrate
chr19_+_4402658	0.256	NM_005483	CHAF1A	chromatin assembly factor 1, subunit A (p150)
chr1_-_17764811	0.256		RCC2	regulator of chromosome condensation 2
chr17_+_45727303	0.255		KPNB1	karyopherin (importin) beta 1
chr1_-_85462622	0.255	NM_153259	MCOLN2	mucolipin 2
chr17_-_3599487	0.253	NM_001204519 NM_001204520 NM_002561 NM_175080	P2RX5-TAX1BP3 P2RX5	P2RX5-TAX1BP3 readthrough purinergic receptor P2X, ligand-gated ion channel, 5
chr3_-_10547221	0.251		ATP2B2	ATPase, Ca++ transporting, plasma membrane 2
chr21_+_35445808	0.250	NM_032476 NM_006933	MRPS6 SLC5A3	mitochondrial ribosomal protein S6 solute carrier family 5 (sodium/myo-inositol cotransporter), member 3
chr3_+_57994087	0.249	NM_001164317 NM_001164318 NM_001164319 NM_001457	FLNB	filamin B, beta
chr19_+_39833099	0.249	NM_018028	SAMD4B	sterile alpha motif domain containing 4B
chr16_-_4401265	0.249	NM_016069	PAM16	presequence translocase-associated motor 16 homolog (S. cerevisiae)
chr7_+_24612714	0.247	NM_016447	MPP6	membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6)
chr1_+_46713385	0.245		RAD54L	RAD54-like (S. cerevisiae)
chr12_+_8850479	0.244	NM_020734	RIMKLB	ribosomal modification protein rimK-like family member B
chr17_+_45727274	0.243	NM_002265	KPNB1	karyopherin (importin) beta 1
chr1_-_11120081	0.243	NM_003132	SRM	spermidine synthase
chr13_-_20806533	0.242	NM_001110219 NM_001110220 NM_001110221	GJB6	gap junction protein, beta 6, 30kDa
chr2_-_216878314	0.241	NM_018000	MREG	melanoregulin
chr16_-_68269948	0.240	NM_024939	ESRP2	epithelial splicing regulatory protein 2
chrX_-_7066146	0.238	NM_001135565 NM_001178135 NM_001178136 NM_012080	HDHD1	haloacid dehalogenase-like hydrolase domain containing 1
chr6_-_143832770	0.238	NM_032020	FUCA2	fucosidase, alpha-L- 2, plasma
chr1_-_6662681	0.238		KLHL21	kelch-like 21 (Drosophila)
chr13_-_99229226	0.238	NM_001032296	STK24	serine/threonine kinase 24
chr1_+_229761988	0.237		URB2	URB2 ribosome biogenesis 2 homolog (S. cerevisiae)
chr11_+_65029312	0.237	NM_002689	POLA2	polymerase (DNA directed), alpha 2 (70kD subunit)
chr16_-_1968230	0.236	NM_001009606	HS3ST6	heparan sulfate (glucosamine) 3-O-sulfotransferase 6
chr22_+_29876180	0.236	NM_021076	NEFH	neurofilament, heavy polypeptide
chr10_+_134210691	0.234	NM_001098637 NM_138499	PWWP2B	PWWP domain containing 2B
chr7_+_116312412	0.233	NM_000245 NM_001127500	MET	met proto-oncogene (hepatocyte growth factor receptor)
chr14_+_103243832	0.233		TRAF3	TNF receptor-associated factor 3
chr2_-_70781146	0.232	NM_001099691 NM_003236	TGFA	transforming growth factor, alpha
chr14_-_53162370	0.232		ERO1L	ERO1-like (S. cerevisiae)
chr7_-_994008	0.232		ADAP1	ArfGAP with dual PH domains 1
chr17_-_17109601	0.230		PLD6	phospholipase D family, member 6
chr22_+_25960885	0.230		ADRBK2	adrenergic, beta, receptor kinase 2
chr7_-_45151272	0.230		TBRG4	transforming growth factor beta regulator 4
chr8_-_145515014	0.228		BOP1	block of proliferation 1
chr8_-_145515099	0.227	NM_015201	BOP1	block of proliferation 1
chr6_-_105850958	0.227		PREP	prolyl endopeptidase
chr8_-_145515089	0.226		BOP1	block of proliferation 1
chr6_-_105850976	0.226	NM_002726	PREP	prolyl endopeptidase
chr19_-_1863425	0.226		KLF16	Kruppel-like factor 16
chr14_+_103243813	0.225	NM_001199427 NM_003300 NM_145725 NM_145726	TRAF3	TNF receptor-associated factor 3
chr17_+_45726838	0.225		KPNB1	karyopherin (importin) beta 1
chr8_-_125740378	0.225		MTSS1	metastasis suppressor 1
chr9_+_133971862	0.224	NM_001185095 NM_001185096 NM_031426	AIF1L	allograft inflammatory factor 1-like
chr17_+_29718777	0.223		RAB11FIP4	RAB11 family interacting protein 4 (class II)
chr8_-_145515071	0.222		BOP1	block of proliferation 1
chr3_+_184032319	0.222		EIF4G1	eukaryotic translation initiation factor 4 gamma, 1
chr11_+_93862143	0.221		PANX1	pannexin 1
chr19_+_38397841	0.221	NM_015073	SIPA1L3	signal-induced proliferation-associated 1 like 3
chr4_+_1873035	0.221	NM_001042424	WHSC1	Wolf-Hirschhorn syndrome candidate 1
chr1_+_117452359	0.219	NM_020440	PTGFRN	prostaglandin F2 receptor negative regulator
chr17_-_41623246	0.219	NM_001986	ETV4	ets variant 4
chr17_+_29718641	0.219	NM_032932	RAB11FIP4	RAB11 family interacting protein 4 (class II)
chr17_-_8021806	0.215	NM_021628	ALOXE3	arachidonate lipoxygenase 3
chr1_-_229761793	0.215	NM_001025247 NM_014409	TAF5L	TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa
chr19_-_46272102	0.215
chr1_-_220101925	0.214	NM_018713	SLC30A10	solute carrier family 30, member 10
chr11_-_119234628	0.214		USP2	ubiquitin specific peptidase 2
chr17_-_40428311	0.214		STAT5B	signal transducer and activator of transcription 5B
chr1_+_118472364	0.214	NM_006784	WDR3	WD repeat domain 3
chrX_-_153285262	0.213		IRAK1	interleukin-1 receptor-associated kinase 1
chr6_+_43738394	0.213		VEGFA	vascular endothelial growth factor A
chr3_-_189838673	0.212		LEPREL1	leprecan-like 1
chr19_+_1248548	0.212	NM_177401	MIDN	midnolin
chr9_-_23821842	0.212	NM_001171195	ELAVL2	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)
chr9_-_23821808	0.211		ELAVL2	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)
chr5_+_90676131	0.211		LOC100129716	uncharacterized LOC100129716
chr17_-_76124791	0.211	NM_001127198	TMC6	transmembrane channel-like 6
chr6_+_43738177	0.211		VEGFA	vascular endothelial growth factor A
chr5_-_1494872	0.211		LPCAT1	lysophosphatidylcholine acyltransferase 1
chr16_+_30194925	0.210		CORO1A	coronin, actin binding protein, 1A
chr19_+_984316	0.209	NM_024100	WDR18	WD repeat domain 18
chr13_-_77460432	0.208	NM_138444	KCTD12	potassium channel tetramerisation domain containing 12
chr7_-_98030426	0.208	NM_018842	BAIAP2L1	BAI1-associated protein 2-like 1
chrX_+_38420690	0.207	NM_004615	TSPAN7	tetraspanin 7
chr3_+_184032414	0.206		EIF4G1	eukaryotic translation initiation factor 4 gamma, 1

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.42	5.59e-31	GO:0044260	cellular macromolecule metabolic process
1.31	3.86e-29	GO:0044237	cellular metabolic process
1.16	6.77e-27	GO:0009987	cellular process
1.29	5.99e-26	GO:0044238	primary metabolic process
1.34	1.29e-24	GO:0043170	macromolecule metabolic process
1.26	2.55e-24	GO:0008152	metabolic process
1.41	3.34e-15	GO:0006139	nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.50	3.65e-15	GO:0043412	macromolecule modification
1.37	6.72e-15	GO:0034641	cellular nitrogen compound metabolic process
1.36	9.89e-15	GO:0006807	nitrogen compound metabolic process
1.50	2.78e-14	GO:0006464	protein modification process
1.41	8.33e-14	GO:0044267	cellular protein metabolic process
1.41	1.41e-11	GO:0090304	nucleic acid metabolic process
1.37	1.40e-10	GO:0044249	cellular biosynthetic process
1.36	3.19e-10	GO:0009058	biosynthetic process
1.32	4.22e-10	GO:0019538	protein metabolic process
1.41	6.82e-09	GO:0010467	gene expression
1.28	8.29e-09	GO:0071840	cellular component organization or biogenesis
1.42	9.47e-09	GO:0016070	RNA metabolic process
1.43	1.64e-08	GO:0006996	organelle organization
1.32	1.64e-08	GO:0071841	cellular component organization or biogenesis at cellular level
1.70	1.09e-07	GO:0051276	chromosome organization
1.53	1.40e-07	GO:0007049	cell cycle
1.40	1.46e-07	GO:0009059	macromolecule biosynthetic process
1.26	1.70e-07	GO:0016043	cellular component organization
1.40	2.09e-07	GO:0034645	cellular macromolecule biosynthetic process
1.16	2.12e-07	GO:0050794	regulation of cellular process
1.52	2.36e-07	GO:0006793	phosphorus metabolic process
1.52	2.36e-07	GO:0006796	phosphate metabolic process
1.43	3.06e-07	GO:0009966	regulation of signal transduction
1.89	5.64e-07	GO:0016568	chromatin modification
1.26	6.07e-07	GO:0060255	regulation of macromolecule metabolic process
1.15	7.60e-07	GO:0050789	regulation of biological process
1.30	8.58e-07	GO:0071842	cellular component organization at cellular level
1.48	1.59e-06	GO:0051246	regulation of protein metabolic process
1.50	1.78e-06	GO:0032268	regulation of cellular protein metabolic process
1.13	1.91e-06	GO:0065007	biological regulation
1.67	2.58e-06	GO:0000278	mitotic cell cycle
1.50	2.62e-06	GO:0006357	regulation of transcription from RNA polymerase II promoter
1.58	3.70e-06	GO:0006468	protein phosphorylation
1.60	4.36e-06	GO:0019220	regulation of phosphate metabolic process
1.60	4.36e-06	GO:0051174	regulation of phosphorus metabolic process
1.37	4.98e-06	GO:0023051	regulation of signaling
1.59	7.29e-06	GO:0022403	cell cycle phase
1.31	1.19e-05	GO:0048523	negative regulation of cellular process
1.59	1.74e-05	GO:0007167	enzyme linked receptor protein signaling pathway
1.22	1.75e-05	GO:0031323	regulation of cellular metabolic process
1.60	1.83e-05	GO:0001932	regulation of protein phosphorylation
1.58	2.02e-05	GO:0042325	regulation of phosphorylation
1.61	2.21e-05	GO:0045934	negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.60	2.42e-05	GO:2000113	negative regulation of cellular macromolecule biosynthetic process
1.29	2.43e-05	GO:0048519	negative regulation of biological process
1.21	2.44e-05	GO:0019222	regulation of metabolic process
1.60	2.77e-05	GO:0051172	negative regulation of nitrogen compound metabolic process
1.22	2.97e-05	GO:0080090	regulation of primary metabolic process
1.69	3.06e-05	GO:0006325	chromatin organization
1.68	5.30e-05	GO:0045859	regulation of protein kinase activity
1.51	6.10e-05	GO:0031399	regulation of protein modification process
1.50	7.00e-05	GO:0022402	cell cycle process
1.55	7.20e-05	GO:0031327	negative regulation of cellular biosynthetic process
1.66	7.86e-05	GO:0043549	regulation of kinase activity
1.45	1.12e-04	GO:0009892	negative regulation of metabolic process
1.55	1.46e-04	GO:0010558	negative regulation of macromolecule biosynthetic process
1.35	1.51e-04	GO:0007399	nervous system development
1.76	1.59e-04	GO:0051301	cell division
1.53	1.67e-04	GO:0009890	negative regulation of biosynthetic process
1.63	1.67e-04	GO:0051338	regulation of transferase activity
1.48	1.69e-04	GO:0016310	phosphorylation
1.46	1.72e-04	GO:0010605	negative regulation of macromolecule metabolic process
1.31	1.81e-04	GO:0044281	small molecule metabolic process
1.55	1.92e-04	GO:0006396	RNA processing
1.60	2.21e-04	GO:0051253	negative regulation of RNA metabolic process
1.61	2.29e-04	GO:0045892	negative regulation of transcription, DNA-dependent
1.56	3.27e-04	GO:0010629	negative regulation of gene expression
1.60	5.77e-04	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
1.81	7.02e-04	GO:0071900	regulation of protein serine/threonine kinase activity
1.43	8.80e-04	GO:0031324	negative regulation of cellular metabolic process
1.19	1.73e-03	GO:0023052	signaling
1.51	1.96e-03	GO:0051726	regulation of cell cycle
1.75	2.21e-03	GO:0051329	interphase of mitotic cell cycle
1.63	3.38e-03	GO:0009968	negative regulation of signal transduction
1.19	3.41e-03	GO:0007165	signal transduction
1.17	4.28e-03	GO:0051716	cellular response to stimulus
1.72	4.59e-03	GO:0051325	interphase
1.67	5.38e-03	GO:0018193	peptidyl-amino acid modification
1.33	6.87e-03	GO:0051641	cellular localization
2.36	7.28e-03	GO:0018196	peptidyl-asparagine modification
2.36	7.28e-03	GO:0018279	protein N-linked glycosylation via asparagine
1.30	7.74e-03	GO:0009653	anatomical structure morphogenesis
1.64	7.88e-03	GO:0044419	interspecies interaction between organisms
1.40	8.83e-03	GO:0006351	transcription, DNA-dependent
1.96	9.93e-03	GO:0006730	one-carbon metabolic process
1.91	1.03e-02	GO:0016569	covalent chromatin modification
1.32	1.22e-02	GO:0033036	macromolecule localization
2.28	1.22e-02	GO:0006487	protein N-linked glycosylation
1.91	1.39e-02	GO:0016570	histone modification
1.40	1.46e-02	GO:0033554	cellular response to stress
1.80	1.51e-02	GO:0048011	nerve growth factor receptor signaling pathway
1.26	1.58e-02	GO:0048583	regulation of response to stimulus
1.34	1.73e-02	GO:0051649	establishment of localization in cell
1.59	2.03e-02	GO:0006397	mRNA processing
1.41	2.06e-02	GO:0046907	intracellular transport
1.58	2.24e-02	GO:0000122	negative regulation of transcription from RNA polymerase II promoter
1.43	2.87e-02	GO:0030182	neuron differentiation
1.54	2.98e-02	GO:0023057	negative regulation of signaling
1.49	3.07e-02	GO:0016071	mRNA metabolic process
1.54	3.32e-02	GO:0010648	negative regulation of cell communication
2.18	3.39e-02	GO:0043414	macromolecule methylation
1.38	3.43e-02	GO:0048699	generation of neurons
1.34	3.62e-02	GO:0010646	regulation of cell communication
1.85	4.59e-02	GO:0006913	nucleocytoplasmic transport
1.50	4.71e-02	GO:0048585	negative regulation of response to stimulus
1.21	4.72e-02	GO:0048522	positive regulation of cellular process
6.54	4.96e-02	GO:0018026	peptidyl-lysine monomethylation

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.17	1.04e-35	GO:0044424	intracellular part
1.16	6.85e-33	GO:0005622	intracellular
1.22	3.26e-28	GO:0043231	intracellular membrane-bounded organelle
1.22	3.92e-28	GO:0043227	membrane-bounded organelle
1.18	1.08e-24	GO:0043226	organelle
1.18	1.45e-24	GO:0043229	intracellular organelle
1.53	3.24e-21	GO:0044428	nuclear part
1.20	3.68e-21	GO:0005737	cytoplasm
1.27	3.20e-19	GO:0005634	nucleus
1.27	1.41e-18	GO:0044446	intracellular organelle part
1.26	8.43e-18	GO:0044422	organelle part
1.53	2.08e-17	GO:0031981	nuclear lumen
1.45	7.25e-17	GO:0031974	membrane-enclosed lumen
1.45	2.24e-16	GO:0070013	intracellular organelle lumen
1.44	8.77e-16	GO:0043233	organelle lumen
1.22	1.69e-13	GO:0044444	cytoplasmic part
1.54	1.91e-12	GO:0005654	nucleoplasm
1.36	7.11e-09	GO:0005829	cytosol
1.05	6.74e-08	GO:0044464	cell part
1.05	7.15e-08	GO:0005623	cell
1.64	7.47e-06	GO:0005730	nucleolus
1.34	1.25e-05	GO:0012505	endomembrane system
1.27	5.65e-05	GO:0031090	organelle membrane
1.22	2.66e-04	GO:0043228	non-membrane-bounded organelle
1.22	2.66e-04	GO:0043232	intracellular non-membrane-bounded organelle
1.18	5.24e-04	GO:0032991	macromolecular complex
1.44	1.10e-03	GO:0044451	nucleoplasm part
1.46	6.46e-03	GO:0005694	chromosome
1.18	7.37e-03	GO:0043234	protein complex
1.44	8.39e-03	GO:0044431	Golgi apparatus part
1.48	1.06e-02	GO:0000139	Golgi membrane
2.16	1.20e-02	GO:0016585	chromatin remodeling complex
2.68	2.18e-02	GO:0017053	transcriptional repressor complex
1.31	3.14e-02	GO:0005794	Golgi apparatus
1.78	3.17e-02	GO:0070161	anchoring junction
2.13	3.97e-02	GO:0046930	pore complex

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.22	6.77e-20	GO:0005515	protein binding
1.12	9.14e-20	GO:0005488	binding
1.46	1.29e-17	GO:0000166	nucleotide binding
1.50	2.53e-14	GO:0016740	transferase activity
1.22	1.25e-11	GO:0003824	catalytic activity
1.47	2.83e-11	GO:0030554	adenyl nucleotide binding
1.47	3.75e-11	GO:0032559	adenyl ribonucleotide binding
1.40	2.00e-10	GO:0017076	purine nucleotide binding
1.41	2.22e-10	GO:0032553	ribonucleotide binding
1.41	2.22e-10	GO:0032555	purine ribonucleotide binding
1.46	2.99e-10	GO:0005524	ATP binding
1.39	1.33e-09	GO:0035639	purine ribonucleoside triphosphate binding
1.64	3.31e-07	GO:0004672	protein kinase activity
1.56	9.20e-07	GO:0019899	enzyme binding
1.50	1.25e-06	GO:0016772	transferase activity, transferring phosphorus-containing groups
1.51	3.72e-06	GO:0003723	RNA binding
1.54	4.55e-06	GO:0016773	phosphotransferase activity, alcohol group as acceptor
1.49	3.30e-05	GO:0016301	kinase activity
1.21	5.45e-05	GO:0003676	nucleic acid binding
1.66	6.27e-05	GO:0004674	protein serine/threonine kinase activity
1.58	8.28e-04	GO:0016874	ligase activity
1.96	9.50e-04	GO:0016741	transferase activity, transferring one-carbon groups
2.30	1.83e-03	GO:0008757	S-adenosylmethionine-dependent methyltransferase activity
1.94	2.13e-03	GO:0000287	magnesium ion binding
1.94	2.13e-03	GO:0008168	methyltransferase activity
2.62	3.43e-03	GO:0008276	protein methyltransferase activity
1.55	4.09e-03	GO:0019904	protein domain specific binding
1.34	7.92e-03	GO:0030528	transcription regulator activity
1.64	8.20e-03	GO:0016564	transcription repressor activity
1.79	1.63e-02	GO:0003682	chromatin binding
1.62	1.82e-02	GO:0008134	transcription factor binding
2.85	2.42e-02	GO:0016278	lysine N-methyltransferase activity
2.85	2.42e-02	GO:0016279	protein-lysine N-methyltransferase activity