Motif ID: HMGA1,2.p2

Z-value: 0.788


Transcription factors associated with HMGA1,2.p2:

Gene SymbolEntrez IDGene Name
HMGA1 3159 high mobility group AT-hook 1
HMGA2 8091 high mobility group AT-hook 2

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
HMGA2chr12_+_662188790.696.1e-02Click!
HMGA1chr6_+_342065670.137.5e-01Click!


Activity profile for motif HMGA1,2.p2.

activity profile for motif HMGA1,2.p2


Sorted Z-values histogram for motif HMGA1,2.p2

Sorted Z-values for motif HMGA1,2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of HMGA1,2.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr10_+_118187381 1.991 NM_001011709
PNLIPRP3
pancreatic lipase-related protein 3
chr20_+_58251715 1.321 NM_001199506
PHACTR3
phosphatase and actin regulator 3
chr5_+_166711842 1.254 NM_001122679
ODZ2
odz, odd Oz/ten-m homolog 2 (Drosophila)
chr3_+_122044010 1.227 NM_005213
CSTA
cystatin A (stefin A)
chr3_-_151034514 1.159 NM_023915
GPR87
G protein-coupled receptor 87
chr7_+_26400503 1.035 NM_001199837
SNX10
sorting nexin 10
chr4_+_40198526 1.022 NM_004310
RHOH
ras homolog gene family, member H
chr3_-_56809594 0.878 NM_001128616
ARHGEF3
Rho guanine nucleotide exchange factor (GEF) 3
chr5_+_140247767 0.857 NM_018902
NM_031861
PCDHA11

protocadherin alpha 11

chr1_-_207205996 0.792 NM_001083924
NM_023938
C1orf116

chromosome 1 open reading frame 116

chr1_+_156030965 0.752 NM_020387
RAB25
RAB25, member RAS oncogene family
chrX_-_78623006 0.674 NM_001171581
NM_004867
ITM2A

integral membrane protein 2A

chr11_-_108464344 0.665 NM_015065
EXPH5
exophilin 5
chr3_+_142342265 0.628 NM_002670
PLS1
plastin 1
chr18_-_61329113 0.609 NM_006919
SERPINB3
serpin peptidase inhibitor, clade B (ovalbumin), member 3
chr5_+_36608430 0.597 NM_001166695
SLC1A3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr8_-_38008332 0.565 NM_000349
STAR
steroidogenic acute regulatory protein
chrX_-_117119282 0.556 NM_001168299
KLHL13
kelch-like 13 (Drosophila)
chrX_+_105937067 0.551 NM_024539
RNF128
ring finger protein 128
chr1_-_11714396 0.547 FBXO2
F-box protein 2
chr9_-_112213663 0.540 NM_001145369
NM_001145370
PTPN3

protein tyrosine phosphatase, non-receptor type 3

chr1_+_186798031 0.538 NM_024420
PLA2G4A
phospholipase A2, group IVA (cytosolic, calcium-dependent)
chr7_+_18548899 0.528 NM_001204147
NM_001204148
HDAC9

histone deacetylase 9

chr5_+_35856990 0.502 NM_002185
IL7R
interleukin 7 receptor
chrX_-_32173585 0.487 NM_004013
NM_004020
NM_004021
NM_004022
NM_004023
DMD




dystrophin




chr2_-_215896809 0.479 NM_015657
ABCA12
ATP-binding cassette, sub-family A (ABC1), member 12
chr7_-_41742666 0.478 NM_002192
INHBA
inhibin, beta A
chr5_+_140165875 0.466 NM_018900
NM_031410
NM_031411
PCDHA1


protocadherin alpha 1


chr7_-_20256942 0.465 NM_182762
MACC1
metastasis associated in colon cancer 1
chr10_+_48255223 0.447 NM_001040084
NM_001098845
ANXA8L2
ANXA8
ANXA8L1
annexin A8-like 2
annexin A8
annexin A8-like 1
chr4_-_10023094 0.444 NM_020041
SLC2A9
solute carrier family 2 (facilitated glucose transporter), member 9
chr1_+_209602164 0.437 NM_001104548
MIR205HG
MIR205 host gene (non-protein coding)
chr6_-_29012951 0.431 NM_030903
OR2W1
olfactory receptor, family 2, subfamily W, member 1
chr12_-_95945226 0.424 NM_032147
USP44
ubiquitin specific peptidase 44
chr18_+_61554938 0.423 NM_001143818
NM_002575
SERPINB2

serpin peptidase inhibitor, clade B (ovalbumin), member 2

chr2_-_113594325 0.412 NM_000576
IL1B
interleukin 1, beta
chr2_+_207804277 0.404 NM_173077
CPO
carboxypeptidase O
chr1_+_86889768 0.402 NM_006536
CLCA2
chloride channel accessory 2
chr2_+_47596447 0.393 EPCAM
epithelial cell adhesion molecule
chrX_+_105412297 0.391 NM_001171020
NM_152423
MUM1L1

melanoma associated antigen (mutated) 1-like 1

chrX_-_15683153 0.383 NM_020665
TMEM27
transmembrane protein 27
chr1_-_153029987 0.377 NM_005988
SPRR2A
small proline-rich protein 2A
chr5_+_36606667 0.373 SLC1A3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr2_+_113875469 0.372 NM_000577
NM_173841
NM_173843
IL1RN


interleukin 1 receptor antagonist


chr14_+_96722546 0.371 NM_000710
BDKRB1
bradykinin receptor B1
chr10_+_74653338 0.369 NM_152635
OIT3
oncoprotein induced transcript 3
chr10_-_105845619 0.367 NM_000494
COL17A1
collagen, type XVII, alpha 1
chr7_-_140302311 0.367 NM_015689
DENND2A
DENN/MADD domain containing 2A
chr6_+_29364331 0.366 NM_013936
OR12D2
olfactory receptor, family 12, subfamily D, member 2
chr5_-_176836535 0.362 NM_000505
F12
coagulation factor XII (Hageman factor)
chr1_+_236557643 0.360 NM_145861
EDARADD
EDAR-associated death domain
chr15_+_52201590 0.354 TMOD3
tropomodulin 3 (ubiquitous)
chr6_-_136847743 0.350 NM_001198614
NM_001198618
NM_001198619
MAP7


microtubule-associated protein 7


chr11_-_104972147 0.349 NM_001007232
NM_001223
NM_033292
NM_033293
NM_033294
NM_033295
CARD17
CASP1




caspase recruitment domain family, member 17
caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase)




chrX_-_33357725 0.348 NM_000109
DMD
dystrophin
chr5_+_31799030 0.347 NM_178140
PDZD2
PDZ domain containing 2
chr1_-_209825797 0.341 NM_000228
LAMB3
laminin, beta 3
chr20_-_43883183 0.340 NM_003064
SLPI
secretory leukocyte peptidase inhibitor
chr7_-_16921596 0.338 NM_176813
AGR3
anterior gradient 3 homolog (Xenopus laevis)
chr8_+_18248754 0.333 NM_000015
NAT2
N-acetyltransferase 2 (arylamine N-acetyltransferase)
chr10_-_118680978 0.330 KIAA1598
KIAA1598
chr4_-_90759446 0.329 NM_001146055
SNCA
synuclein, alpha (non A4 component of amyloid precursor)
chr8_-_80993009 0.327 NM_001025252
TPD52
tumor protein D52
chr7_+_143412938 0.327 NM_001130026
FAM115C
family with sequence similarity 115, member C
chr3_-_112693711 0.327 NM_138806
NM_138939
NM_138940
NM_170780
CD200R1



CD200 receptor 1



chrX_+_41548225 0.304 NM_001097579
NM_005300
GPR34

G protein-coupled receptor 34

chr15_+_80364902 0.302 NM_001242915
NM_001242916
ZFAND6

zinc finger, AN1-type domain 6

chr19_+_41281281 0.302 NM_006533
MIA
melanoma inhibitory activity
chr12_+_29376596 0.300 NM_018099
FAR2
fatty acyl CoA reductase 2
chr11_+_10476665 0.298 NM_001025389
AMPD3
adenosine monophosphate deaminase 3
chr13_+_97874704 0.296 MBNL2
muscleblind-like 2 (Drosophila)
chr1_+_77333158 0.294 NM_030965
ST6GALNAC5
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5
chr3_+_113616317 0.291 NM_001172105
GRAMD1C
GRAM domain containing 1C
chr10_-_5446781 0.291 NM_001171864
NM_024803
TUBAL3

tubulin, alpha-like 3

chr14_+_21525980 0.289 NM_138331
RNASE8
ribonuclease, RNase A family, 8
chr1_+_84864214 0.289 NM_021233
DNASE2B
deoxyribonuclease II beta
chr10_-_62332666 0.287 NM_001204404
ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr18_+_29027731 0.287 NM_001944
DSG3
desmoglein 3
chr5_+_147258273 0.287 NM_054023
SCGB3A2
secretoglobin, family 3A, member 2
chr11_-_18062304 0.287 NM_004179
TPH1
tryptophan hydroxylase 1
chr11_-_85430117 0.282 NM_206929
SYTL2
synaptotagmin-like 2
chr11_+_67351276 0.281 GSTP1
glutathione S-transferase pi 1
chr2_-_238499317 0.280 RAB17
RAB17, member RAS oncogene family
chr4_-_159956332 0.275 NM_152543
C4orf45
chromosome 4 open reading frame 45
chr12_-_8815370 0.274 NM_003480
MFAP5
microfibrillar associated protein 5
chr1_-_153085963 0.266 NM_001014450
SPRR2A
SPRR2F
small proline-rich protein 2A
small proline-rich protein 2F
chr5_+_36606456 0.265 NM_001166696
NM_004172
SLC1A3

solute carrier family 1 (glial high affinity glutamate transporter), member 3

chr19_+_7030593 0.263 NM_001136507
MBD3L5
methyl-CpG binding domain protein 3-like 5
chr4_+_175839508 0.263 NM_001130703
NM_001130704
NM_001130705
NM_014269
ADAM29



ADAM metallopeptidase domain 29



chr1_+_158223926 0.258 NM_001763
CD1A
CD1a molecule
chr17_-_54893249 0.257 NM_001085430
C17orf67
chromosome 17 open reading frame 67
chr11_-_85425790 0.254 NM_032379
SYTL2
synaptotagmin-like 2
chr1_+_212475147 0.254 NM_001199756
PPP2R5A
protein phosphatase 2, regulatory subunit B', alpha
chr1_+_244216506 0.253 NM_006352
ZNF238
zinc finger protein 238
chr2_+_234590583 0.253 NM_019077
UGT1A7
UDP glucuronosyltransferase 1 family, polypeptide A7
chr5_+_161494647 0.252 NM_000816
NM_198903
NM_198904
GABRG2


gamma-aminobutyric acid (GABA) A receptor, gamma 2


chr1_-_204459445 0.252 NM_002646
PIK3C2B
phosphoinositide-3-kinase, class 2, beta polypeptide
chr19_-_7058644 0.252 NM_001164425
MBD3L3
methyl-CpG binding domain protein 3-like 3
chr1_-_161337663 0.249 NM_001013625
C1orf192
chromosome 1 open reading frame 192
chr7_+_150382783 0.249 NM_015660
GIMAP2
GTPase, IMAP family member 2
chr20_+_31805118 0.246 NM_001042439
NM_178466
BPIFA3

BPI fold containing family A, member 3

chr17_-_48945338 0.246 NM_001243877
TOB1
transducer of ERBB2, 1
chr7_-_16505292 0.246 NM_015464
SOSTDC1
sclerostin domain containing 1
chr5_-_176836488 0.245 F12
coagulation factor XII (Hageman factor)
chrX_-_32430370 0.244 NM_004011
NM_004012
DMD

dystrophin

chr19_+_20959109 0.242


chr6_-_136847609 0.239 MAP7
microtubule-associated protein 7
chr12_+_21168629 0.239 NM_001009562
SLCO1B7
solute carrier organic anion transporter family, member 1B7 (non-functional)
chr19_-_7040183 0.237 NM_001164419
MBD3L4
methyl-CpG binding domain protein 3-like 4
chr5_+_68800003 0.237 NM_001205255
OCLN
occludin
chr1_+_205473683 0.236 NM_002596
NM_212502
NM_212503
CDK18


cyclin-dependent kinase 18


chr11_-_16497917 0.236 NM_033326
SOX6
SRY (sex determining region Y)-box 6
chr18_-_29340698 0.235 NM_001034172
MCART2
mitochondrial carrier triple repeat 2
chr2_+_191002485 0.234 NM_001042521
C2orf88
chromosome 2 open reading frame 88
chr11_-_102651321 0.234 NM_002425
MMP10
matrix metallopeptidase 10 (stromelysin 2)
chr19_-_35981345 0.231 NM_001244847
NM_207392
KRTDAP

keratinocyte differentiation-associated protein

chr3_-_190167597 0.231 NM_207316
TMEM207
transmembrane protein 207
chr1_-_205391180 0.229 NM_001001552
NM_001199050
NM_001199051
NM_001199052
LEMD1



LEM domain containing 1



chr2_-_69180011 0.228 NM_182536
GKN2
gastrokine 2
chr17_-_39675078 0.228 NM_002275
KRT15
keratin 15
chr19_+_6135650 0.226 NM_030924
ACSBG2
acyl-CoA synthetase bubblegum family member 2
chr4_+_100737980 0.226 NM_014395
DAPP1
dual adaptor of phosphotyrosine and 3-phosphoinositides
chr4_-_87281374 0.224 NM_138980
NM_138982
MAPK10

mitogen-activated protein kinase 10

chr1_+_84874033 0.223 NM_058248
DNASE2B
deoxyribonuclease II beta
chr1_+_206730591 0.222 RASSF5
Ras association (RalGDS/AF-6) domain family member 5
chrX_+_138612894 0.222 NM_000133
F9
coagulation factor IX
chr4_+_159131400 0.222 NM_018342
TMEM144
transmembrane protein 144
chr1_+_13911966 0.220 NM_001006624
NM_001006625
PDPN

podoplanin

chr7_+_121513158 0.220 NM_001206838
NM_001206839
NM_002851
PTPRZ1


protein tyrosine phosphatase, receptor-type, Z polypeptide 1


chr4_-_153303663 0.219 NM_001013415
FBXW7
F-box and WD repeat domain containing 7
chr1_-_186417855 0.217 NM_022576
PDC
phosducin
chr19_-_4338750 0.216 NM_001013841
NM_017720
STAP2

signal transducing adaptor family member 2

chr4_+_140587086 0.216 MGST2
microsomal glutathione S-transferase 2
chr4_-_72649734 0.213 NM_000583
GC
group-specific component (vitamin D binding protein)
chr7_-_7758237 0.212 NM_002947
RPA3
replication protein A3, 14kDa
chr3_-_57530067 0.212 NM_178504
NM_198564
DNAH12

dynein, axonemal, heavy chain 12

chr4_-_77328457 0.212 NM_001042784
CCDC158
coiled-coil domain containing 158
chr5_-_35938736 0.212 NM_001042625
NM_144647
CAPSL

calcyphosine-like

chr4_-_110723127 0.210 CFI
complement factor I
chr22_-_45608346 0.210 NM_015264
KIAA0930
KIAA0930
chr1_-_242612757 0.209 NM_001195811
NM_001195812
PLD5

phospholipase D family, member 5

chr21_-_27945267 0.208 NM_052954
CYYR1
cysteine/tyrosine-rich 1
chrX_-_114252132 0.206 NM_000640
IL13RA2
interleukin 13 receptor, alpha 2
chr17_-_39274587 0.206 NM_033059
KRTAP4-11
keratin associated protein 4-11
chr17_-_56494889 0.205 RNF43
ring finger protein 43
chr13_-_20767100 0.204 NM_004004
GJB2
gap junction protein, beta 2, 26kDa
chr13_+_97874540 0.204 NM_144778
NM_207304
MBNL2

muscleblind-like 2 (Drosophila)

chr5_+_140346053 0.204 PCDHAC2
protocadherin alpha subfamily C, 2
chr11_-_67450536 0.204 RPL37
ribosomal protein L37
chr11_-_128894008 0.204 NM_014715
ARHGAP32
Rho GTPase activating protein 32
chr4_-_123377471 0.204 NM_000586
IL2
interleukin 2
chr19_+_41281081 0.202 NM_001202553
MIA
melanoma inhibitory activity
chr17_-_56492938 0.202 RNF43
ring finger protein 43
chr18_+_11689135 0.202 NM_182978
GNAL
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type
chr10_+_5238756 0.200 NM_001818
AKR1C4
aldo-keto reductase family 1, member C4 (chlordecone reductase; 3-alpha hydroxysteroid dehydrogenase, type I; dihydrodiol dehydrogenase 4)
chr13_+_43355685 0.200 NM_182508
C13orf30
chromosome 13 open reading frame 30
chr13_-_20767036 0.199 GJB2
gap junction protein, beta 2, 26kDa
chr14_-_20797532 0.199 NM_182852
NM_182851
CCNB1IP1

cyclin B1 interacting protein 1, E3 ubiquitin protein ligase

chr21_-_33074101 0.199 SCAF4
SR-related CTD-associated factor 4
chr11_-_125648704 0.197 NM_212555
PATE2
prostate and testis expressed 2
chr4_+_71337674 0.197 NM_001145007
MUC7
mucin 7, secreted
chr3_-_197300193 0.197 NM_203315
BDH1
3-hydroxybutyrate dehydrogenase, type 1
chr20_+_9458460 0.196 PLCB4
phospholipase C, beta 4
chr6_+_13924676 0.196 NM_001165034
RNF182
ring finger protein 182
chr2_+_103035148 0.195 NM_003853
IL18RAP
interleukin 18 receptor accessory protein
chr9_+_137004913 0.194 NM_052821
WDR5
WD repeat domain 5
chrX_-_70326637 0.194 NM_001025265
CXorf65
chromosome X open reading frame 65
chr3_-_42843217 0.193


chr11_+_5641173 0.191 NM_001003827
TRIM34
tripartite motif containing 34
chr4_-_88450243 0.191 SPARCL1
SPARC-like 1 (hevin)
chr11_-_85469043 0.191 NM_001162951
NM_001162953
SYTL2

synaptotagmin-like 2

chr13_+_97928414 0.190 MBNL2
muscleblind-like 2 (Drosophila)
chr1_+_152956563 0.189 NM_001199828
NM_005987
SPRR1A

small proline-rich protein 1A

chr1_-_183559669 0.188 NM_000433
NM_001190789
NM_001190794
NCF2


neutrophil cytosolic factor 2


chr5_+_140345746 0.188 NM_018899
PCDHAC2
protocadherin alpha subfamily C, 2
chr18_+_61442611 0.187 NM_003784
SERPINB7
serpin peptidase inhibitor, clade B (ovalbumin), member 7
chr1_+_167599329 0.186 NM_052862
RCSD1
RCSD domain containing 1
chr18_+_616671 0.186 NM_199167
CLUL1
clusterin-like 1 (retinal)
chr4_+_88896868 0.185 SPP1
secreted phosphoprotein 1
chr14_+_39735871 0.184 CTAGE5
CTAGE family, member 5
chr6_-_43595079 0.184 GTPBP2
GTP binding protein 2
chr18_+_55714457 0.184 NM_001144964
NEDD4L
neural precursor cell expressed, developmentally down-regulated 4-like
chr3_+_39371196 0.183 NM_005201
CCR8
chemokine (C-C motif) receptor 8
chr4_+_71337833 0.182 NM_152291
MUC7
mucin 7, secreted
chr5_+_140254930 0.181 NM_018903
NM_031864
PCDHA12

protocadherin alpha 12

chr12_+_48516428 0.181 NM_001166687
NM_001166688
PFKM

phosphofructokinase, muscle

chr1_+_196857143 0.181 NM_001201550
NM_001201551
NM_006684
CFHR4


complement factor H-related 4


chr6_+_132859426 0.180 NM_175057
TAAR9
trace amine associated receptor 9 (gene/pseudogene)
chr3_-_93747453 0.180 NM_001001850
STX19
syntaxin 19
chr18_+_20735788 0.180 NM_138375
CABLES1
Cdk5 and Abl enzyme substrate 1
chr18_-_53089722 0.179 NM_001243233
TCF4
transcription factor 4
chr4_+_88896838 0.178 SPP1
secreted phosphoprotein 1
chr18_+_61575203 0.177 SERPINB10
serpin peptidase inhibitor, clade B (ovalbumin), member 10
chr4_+_69313166 0.175 NM_014058
TMPRSS11E
transmembrane protease, serine 11E
chr1_-_247921707 0.174 NM_012353
OR1C1
olfactory receptor, family 1, subfamily C, member 1
chr5_-_41261539 0.174 NM_001115131
C6
complement component 6
chr4_-_122854192 0.173 NM_003305
TRPC3
transient receptor potential cation channel, subfamily C, member 3
chr18_+_61582744 0.173 NM_005024
SERPINB10
serpin peptidase inhibitor, clade B (ovalbumin), member 10
chr14_+_23305816 0.173 MMP14
matrix metallopeptidase 14 (membrane-inserted)
chr10_+_695887 0.173 C10orf108
chromosome 10 open reading frame 108

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.45 6.26e-05 GO:0002376 immune system process
1.53 1.12e-03 GO:0006955 immune response
1.49 2.80e-03 GO:0006952 defense response
1.71 8.62e-03 GO:0045087 innate immune response
5.09 9.51e-03 GO:0015721 bile acid and bile salt transport
2.68 1.06e-02 GO:0050671 positive regulation of lymphocyte proliferation
2.64 1.38e-02 GO:0032946 positive regulation of mononuclear cell proliferation
2.61 1.80e-02 GO:0070665 positive regulation of leukocyte proliferation
2.99 3.09e-02 GO:0042102 positive regulation of T cell proliferation
2.27 4.24e-02 GO:0070663 regulation of leukocyte proliferation

Nothing significant found in compartment category.

Nothing significant found in function category.