Motif ID: HMX1.p2

Z-value: 1.794


Transcription factors associated with HMX1.p2:

Gene SymbolEntrez IDGene Name
HMX1 3166 H6 family homeobox 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
HMX1chr4_-_88734530.413.1e-01Click!


Activity profile for motif HMX1.p2.

activity profile for motif HMX1.p2


Sorted Z-values histogram for motif HMX1.p2

Sorted Z-values for motif HMX1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of HMX1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr14_-_105634708 4.149 JAG2
jagged 2
chr8_+_95653272 3.164 ESRP1
epithelial splicing regulatory protein 1
chr1_-_27286875 2.846 NM_152365
 C1orf172
chromosome 1 open reading frame 172
chr8_-_75233461 2.649 NM_020647
 JPH1
junctophilin 1
chr1_+_156030965 2.238 NM_020387
 RAB25
RAB25, member RAS oncogene family
chr11_+_69924407 2.193 NM_018043
 ANO1
anoctamin 1, calcium activated chloride channel
chr19_+_35607218 2.176 FXYD3
FXYD domain containing ion transport regulator 3
chr14_-_105635114 1.998 NM_002226
NM_145159
 JAG2

jagged 2

chr3_-_111314181 1.863 NM_024508
 ZBED2
zinc finger, BED-type containing 2
chr19_-_10697907 1.848 NM_005498
 AP1M2
adaptor-related protein complex 1, mu 2 subunit
chr19_+_38755097 1.848 NM_001166103
NM_021102
 SPINT2

serine peptidase inhibitor, Kunitz type, 2

chr19_+_38755238 1.825 SPINT2
serine peptidase inhibitor, Kunitz type, 2
chr8_+_31497267 1.774 NM_013962
 NRG1
neuregulin 1
chr6_-_136871956 1.758 NM_001198616
NM_001198617
NM_003980
 MAP7


microtubule-associated protein 7


chr19_+_38755422 1.754 SPINT2
serine peptidase inhibitor, Kunitz type, 2
chr12_+_4382882 1.730 NM_001759
 CCND2
cyclin D2
chr9_-_136024522 1.692 NM_001042368
 RALGDS
ral guanine nucleotide dissociation stimulator
chr7_+_145813828 1.661 CNTNAP2
contactin associated protein-like 2
chr17_-_7166263 1.504 NM_001185023
NM_001307
 CLDN7

claudin 7

chr9_-_23821477 1.475 NM_001171197
 ELAVL2
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 21 entries
enrichment   p-value GO term description
8.08 4.68e-02 GO:0060678 dichotomous subdivision of terminal units involved in ureteric bud branching
3.59 1.14e-02 GO:0060560 developmental growth involved in morphogenesis
2.84 5.97e-03 GO:0051216 cartilage development
2.04 3.20e-02 GO:0048011 nerve growth factor receptor signaling pathway
1.81 1.58e-02 GO:0007264 small GTPase mediated signal transduction
1.71 3.91e-02 GO:0051094 positive regulation of developmental process
1.48 1.19e-02 GO:0043067 regulation of programmed cell death
1.48 1.25e-02 GO:0042981 regulation of apoptosis
1.47 4.29e-03 GO:0050790 regulation of catalytic activity
1.47 1.65e-02 GO:0010941 regulation of cell death
1.40 7.88e-03 GO:0065009 regulation of molecular function
1.39 3.72e-02 GO:0035556 intracellular signal transduction
1.38 3.20e-02 GO:0009966 regulation of signal transduction
1.35 3.78e-02 GO:0023051 regulation of signaling
1.34 1.62e-02 GO:0048513 organ development
1.29 2.18e-02 GO:0048522 positive regulation of cellular process
1.28 7.13e-03 GO:0048518 positive regulation of biological process
1.23 3.23e-02 GO:0007165 signal transduction
1.22 2.12e-02 GO:0023052 signaling
1.13 2.94e-02 GO:0065007 biological regulation

Gene overrepresentation in compartment category:

Showing 1 to 3 of 3 entries
enrichment   p-value GO term description
1.37 4.02e-05 GO:0005829 cytosol
1.27 1.93e-02 GO:0044459 plasma membrane part
1.10 3.67e-02 GO:0005737 cytoplasm

Gene overrepresentation in function category:

Showing 1 to 5 of 5 entries
enrichment   p-value GO term description
5.65 4.54e-04 GO:0004864 protein phosphatase inhibitor activity
5.17 4.71e-04 GO:0019212 phosphatase inhibitor activity
1.82 3.53e-02 GO:0004857 enzyme inhibitor activity
1.18 1.45e-06 GO:0005515 protein binding
1.08 1.67e-03 GO:0005488 binding