Motif ID: HNF1A.p2

Z-value: 1.042


Transcription factors associated with HNF1A.p2:

Gene SymbolEntrez IDGene Name
HNF1A 6927 HNF1 homeobox A

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
HNF1Achr12_+_1214162940.531.8e-01Click!


Activity profile for motif HNF1A.p2.

activity profile for motif HNF1A.p2


Sorted Z-values histogram for motif HNF1A.p2

Sorted Z-values for motif HNF1A.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of HNF1A.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_+_74347461 0.968 NM_001133
AFM
afamin
chr14_-_94854910 0.913 SERPINA1
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
chr6_-_24383519 0.824 NM_001195610
DCDC2
doublecortin domain containing 2
chr6_-_29012951 0.747 NM_030903
OR2W1
olfactory receptor, family 2, subfamily W, member 1
chr14_-_94855120 0.659 NM_000295
SERPINA1
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
chr17_+_73553883 0.634 LLGL2
lethal giant larvae homolog 2 (Drosophila)
chr14_-_92333856 0.530 NM_001128596
TC2N
tandem C2 domains, nuclear
chr8_-_17555158 0.530 NM_020749
MTUS1
microtubule associated tumor suppressor 1
chr19_+_15052298 0.523 NM_012377
OR7C2
olfactory receptor, family 7, subfamily C, member 2
chr8_+_21911062 0.474 NM_001114137
EPB49
erythrocyte membrane protein band 4.9 (dematin)
chr19_-_36303724 0.473 PRODH2
proline dehydrogenase (oxidase) 2
chr22_+_45098046 0.419 NM_181333
PRR5
proline rich 5 (renal)
chr6_-_116381765 0.417 NM_002031
FRK
fyn-related kinase
chr4_-_110723127 0.406 CFI
complement factor I
chr4_-_155511838 0.402 NM_000508
NM_021871
FGA

fibrinogen alpha chain

chr16_-_66952729 0.391 NM_001204744
NM_001204745
NM_001204746
NM_004062
CDH16



cadherin 16, KSP-cadherin



chr19_-_36303766 0.383 PRODH2
proline dehydrogenase (oxidase) 2
chrX_-_15683153 0.376 NM_020665
TMEM27
transmembrane protein 27
chr17_+_1646129 0.368 NM_000934
NM_001165921
SERPINF2

serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2

chr4_-_186733372 0.357 NM_003603
NM_001145670
SORBS2

sorbin and SH3 domain containing 2

chr22_+_32439250 0.346 SLC5A1
solute carrier family 5 (sodium/glucose cotransporter), member 1
chr4_-_110723334 0.336 NM_000204
CFI
complement factor I
chr20_+_42984338 0.323 NM_001030003
NM_001030004
NM_175914
HNF4A


hepatocyte nuclear factor 4, alpha


chrX_-_33146543 0.316 NM_004010
NM_004009
DMD

dystrophin

chr22_+_45098091 0.311 NM_181334
PRR5-ARHGAP8
PRR5
PRR5-ARHGAP8 readthrough
proline rich 5 (renal)
chr16_-_48269087 0.294 NM_032583
NM_145186
ABCC11

ATP-binding cassette, sub-family C (CFTR/MRP), member 11

chr3_-_161089747 0.285 NM_001040100
SPTSSB
serine palmitoyltransferase, small subunit B
chr14_+_95027760 0.254 NM_006215
SERPINA4
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4
chr2_-_216003068 0.251 NM_173076
ABCA12
ATP-binding cassette, sub-family A (ABC1), member 12
chr13_+_97874704 0.244 MBNL2
muscleblind-like 2 (Drosophila)
chr4_-_69434215 0.239 NM_001077
UGT2B15
UGT2B17
UDP glucuronosyltransferase 2 family, polypeptide B15
UDP glucuronosyltransferase 2 family, polypeptide B17
chr20_+_43030005 0.236 HNF4A
hepatocyte nuclear factor 4, alpha
chr8_-_124749573 0.235 NM_001003954
NM_004306
ANXA13

annexin A13

chr1_+_81771844 0.232 LPHN2
latrophilin 2
chr10_+_85933553 0.230 NM_207373
C10orf99
chromosome 10 open reading frame 99
chr16_+_21245015 0.227 NM_145865
ANKS4B
ankyrin repeat and sterile alpha motif domain containing 4B
chr18_+_29027731 0.226 NM_001944
DSG3
desmoglein 3
chr4_-_72649734 0.222 NM_000583
GC
group-specific component (vitamin D binding protein)
chr10_+_5136613 0.218 AKR1C3
aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)
chrX_+_135251454 0.218 NM_001159704
FHL1
four and a half LIM domains 1
chr10_+_5136556 0.216 NM_003739
AKR1C3
aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)
chr14_+_65171243 0.214 PLEKHG3
pleckstrin homology domain containing, family G (with RhoGef domain) member 3
chr10_+_5136589 0.213 AKR1C3
aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)
chr19_-_33360641 0.208 NM_001126335
NM_001243036
NM_014270
SLC7A9


solute carrier family 7 (glycoprotein-associated amino acid transporter light chain, bo,+ system), member 9


chr17_+_1646290 0.196 NM_001165920
SERPINF2
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2
chr16_-_20364029 0.195 NM_001008389
NM_003361
UMOD

uromodulin

chr6_+_121756744 0.190 NM_000165
GJA1
gap junction protein, alpha 1, 43kDa
chrX_+_107288199 0.189 NM_001170553
NM_182607
VSIG1

V-set and immunoglobulin domain containing 1

chr12_-_22487566 0.188 NM_003034
ST8SIA1
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1
chr20_+_9288446 0.180 NM_000933
PLCB4
phospholipase C, beta 4
chr16_-_3085541 0.176 NM_001103175
CCDC64B
coiled-coil domain containing 64B
chr5_-_135290521 0.175 NM_002302
LECT2
leukocyte cell-derived chemotaxin 2
chr2_+_27719702 0.174 NM_001486
GCKR
glucokinase (hexokinase 4) regulator
chr2_-_228244005 0.174 NM_024795
TM4SF20
transmembrane 4 L six family member 20
chr11_+_121461070 0.173 SORL1
sortilin-related receptor, L(DLR class) A repeats containing
chr22_+_32439018 0.170 NM_000343
SLC5A1
solute carrier family 5 (sodium/glucose cotransporter), member 1
chr1_+_119911395 0.170 NM_001005783
NM_016527
HAO2

hydroxyacid oxidase 2 (long chain)

chr12_+_9980076 0.170 NM_016523
KLRF1
killer cell lectin-like receptor subfamily F, member 1
chr4_+_74301932 0.165 NM_001134
AFP
alpha-fetoprotein
chr15_+_58430394 0.165 NM_020980
AQP9
aquaporin 9
chr2_+_234668914 0.164 NM_000463
UGT1A1
UDP glucuronosyltransferase 1 family, polypeptide A1
chr12_+_25205488 0.162 LRMP
lymphoid-restricted membrane protein
chr6_-_33548017 0.158 NM_001188
BAK1
BCL2-antagonist/killer 1
chr8_+_76320106 0.156 HNF4G
hepatocyte nuclear factor 4, gamma
chr6_-_25874439 0.156 NM_001098486
NM_006632
SLC17A3

solute carrier family 17 (sodium phosphate), member 3

chr7_+_139528951 0.155 NM_001061
NM_001166253
NM_030984
TBXAS1


thromboxane A synthase 1 (platelet)


chr2_+_182850550 0.155 NM_001080545
PPP1R1C
protein phosphatase 1, regulatory (inhibitor) subunit 1C
chr12_+_20963637 0.150 NM_019844
SLCO1B3
solute carrier organic anion transporter family, member 1B3
chr6_-_30899926 0.147 NM_205854
SFTA2
surfactant associated 2
chr14_+_39703119 0.138 NM_054024
MIA2
melanoma inhibitory activity 2
chr7_+_129015483 0.138 NM_001130722
AHCYL2
adenosylhomocysteinase-like 2
chr15_+_40509628 0.138 NM_001128628
NM_001128629
PAK6

p21 protein (Cdc42/Rac)-activated kinase 6

chr20_-_44538654 0.138 PLTP
phospholipid transfer protein
chr6_+_161123224 0.133 NM_000301
NM_001168338
PLG

plasminogen

chr6_-_51952368 0.132 NM_138694
NM_170724
PKHD1

polycystic kidney and hepatic disease 1 (autosomal recessive)

chr2_+_234526290 0.132 NM_019076
UGT1A8
UDP glucuronosyltransferase 1 family, polypeptide A8
chr19_-_36304200 0.132 NM_021232
PRODH2
proline dehydrogenase (oxidase) 2
chr12_-_18243052 0.126 NM_024730
RERGL
RERG/RAS-like
chr17_+_67498391 0.126 MAP2K6
mitogen-activated protein kinase kinase 6
chr6_-_33547833 0.125 BAK1
BCL2-antagonist/killer 1
chr4_+_74269971 0.125 NM_000477
ALB
albumin
chr4_+_3443691 0.121 NM_001528
HGFAC
HGF activator
chr1_+_159557615 0.120 NM_001639
APCS
amyloid P component, serum
chr12_-_22089627 0.120 NM_005691
NM_020297
ABCC9

ATP-binding cassette, sub-family C (CFTR/MRP), member 9

chr1_-_103496768 0.116 COL11A1
collagen, type XI, alpha 1
chr3_-_141719188 0.112 NM_001178140
TFDP2
transcription factor Dp-2 (E2F dimerization partner 2)
chr20_-_7921068 0.111 NM_017545
HAO1
hydroxyacid oxidase (glycolate oxidase) 1
chr8_-_87242508 0.111 NM_138817
SLC7A13
solute carrier family 7 (anionic amino acid transporter), member 13
chr11_+_46740769 0.110 F2
coagulation factor II (thrombin)
chr11_+_46740736 0.110 NM_000506
F2
coagulation factor II (thrombin)
chr6_-_32497925 0.109 NM_002125
HLA-DRB5
major histocompatibility complex, class II, DR beta 5
chr16_+_81272293 0.108 NM_017429
BCMO1
beta-carotene 15,15'-monooxygenase 1
chr2_+_234601511 0.106 NM_001072
UGT1A6
UDP glucuronosyltransferase 1 family, polypeptide A6
chr1_+_84768333 0.105 NM_001134664
SAMD13
sterile alpha motif domain containing 13
chr7_+_73275488 0.104 NM_182504
WBSCR28
Williams-Beuren syndrome chromosome region 28
chr11_-_117695408 0.104 NM_001680
FXYD2
FXYD domain containing ion transport regulator 2
chr9_-_94712079 0.103 NM_004560
ROR2
receptor tyrosine kinase-like orphan receptor 2
chr4_+_3443659 0.103 HGFAC
HGF activator
chr7_-_104567089 0.102 LOC723809
uncharacterized LOC723809
chr17_+_35732927 0.100 NM_173625
C17orf78
chromosome 17 open reading frame 78
chr12_-_123834984 0.100 NM_001167856
NM_018183
SBNO1

strawberry notch homolog 1 (Drosophila)

chr11_-_64825992 0.100 NM_005468
NAALADL1
N-acetylated alpha-linked acidic dipeptidase-like 1
chr17_-_38938785 0.099 NM_181537
KRT27
keratin 27
chr16_-_55909208 0.099 NM_001143685
NM_145024
CES5A

carboxylesterase 5A

chr1_-_67266930 0.098 NM_005478
INSL5
insulin-like 5
chr10_+_111765725 0.098 NM_019903
ADD3
adducin 3 (gamma)
chr16_+_89696775 0.097 DPEP1
dipeptidase 1 (renal)
chr19_-_42133427 0.096 NM_001817
CEACAM4
carcinoembryonic antigen-related cell adhesion molecule 4
chr13_-_101185944 0.096 NM_033110
A2LD1
AIG2-like domain 1
chr2_+_102608305 0.095 NM_004633
IL1R2
interleukin 1 receptor, type II
chr6_+_167536240 0.094 NM_031409
CCR6
chemokine (C-C motif) receptor 6
chr9_+_93589704 0.093 NM_001174167
SYK
spleen tyrosine kinase
chr9_-_21305311 0.093 NM_002169
IFNA5
interferon, alpha 5
chr2_+_234637772 0.091 NM_019093
UGT1A3
UDP glucuronosyltransferase 1 family, polypeptide A3
chr6_+_126070738 0.090 HEY2
hairy/enhancer-of-split related with YRPW motif 2
chr10_+_135340865 0.090 NM_000773
CYP2E1
cytochrome P450, family 2, subfamily E, polypeptide 1
chr2_+_102615456 0.088 NM_173343
IL1R2
interleukin 1 receptor, type II
chr17_-_64225496 0.088 NM_000042
APOH
apolipoprotein H (beta-2-glycoprotein I)
chr2_+_167744996 0.088 NM_001079810
NM_001199143
NM_152381
XIRP2


xin actin-binding repeat containing 2


chr12_-_102874373 0.087 NM_000618
NM_001111283
NM_001111285
IGF1


insulin-like growth factor 1 (somatomedin C)


chr14_-_94759360 0.087 NM_016186
SERPINA10
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10
chr9_-_71155729 0.087 NM_153237
C9orf71
chromosome 9 open reading frame 71
chr9_+_130860816 0.086 NM_052901
NM_001006643
SLC25A25

solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25

chr19_-_39443326 0.085 NM_148169
FBXO17
F-box protein 17
chr4_-_122854192 0.085 NM_003305
TRPC3
transient receptor potential cation channel, subfamily C, member 3
chr4_+_57036360 0.084 NM_020722
KIAA1211
KIAA1211
chr19_-_11639929 0.083 NM_001142464
NM_001142465
NM_016581
ECSIT


ECSIT homolog (Drosophila)


chr19_-_43098980 0.082 NM_001816
CEACAM8
carcinoembryonic antigen-related cell adhesion molecule 8
chr3_-_196911001 0.081 NM_001204387
NM_001204388
DLG1

discs, large homolog 1 (Drosophila)

chr5_+_140247767 0.080 NM_018902
NM_031861
PCDHA11

protocadherin alpha 11

chr20_-_22564893 0.080 FOXA2
forkhead box A2
chr14_-_94759594 0.077 NM_001100607
SERPINA10
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10
chr19_+_45417576 0.077 APOC1
apolipoprotein C-I
chr12_-_102874321 0.076 IGF1
insulin-like growth factor 1 (somatomedin C)
chr3_+_160394946 0.075 NM_025047
ARL14
ADP-ribosylation factor-like 14
chr21_-_36231794 0.073 RUNX1
runt-related transcription factor 1
chr2_+_234627423 0.073 NM_007120
UGT1A4
UDP glucuronosyltransferase 1 family, polypeptide A4
chr3_-_57234279 0.073 NM_003865
HESX1
HESX homeobox 1
chr17_+_73642645 0.072 NM_001162997
C17orf110
chromosome 17 open reading frame 110
chr6_-_33754712 0.071 NM_001143944
LEMD2
LEM domain containing 2
chr4_-_100273831 0.071 NM_000669
ADH1C
alcohol dehydrogenase 1C (class I), gamma polypeptide
chr7_-_37025696 0.069 ELMO1
engulfment and cell motility 1
chr4_+_169013687 0.067 NM_007193
ANXA10
annexin A10
chr2_+_234580504 0.066 NM_021027
UGT1A9
UDP glucuronosyltransferase 1 family, polypeptide A9
chr11_+_71900958 0.066 NM_000802
FOLR1
folate receptor 1 (adult)
chr17_+_41052813 0.065 NM_000151
G6PC
glucose-6-phosphatase, catalytic subunit
chr4_-_100212085 0.065 NM_000667
ADH1A
alcohol dehydrogenase 1A (class I), alpha polypeptide
chr15_+_58724174 0.065 NM_000236
LIPC
lipase, hepatic
chr17_+_77020229 0.065 NM_030968
NM_198594
C1QTNF1

C1q and tumor necrosis factor related protein 1

chr10_+_695887 0.064 C10orf108
chromosome 10 open reading frame 108
chr14_-_94759556 0.064 SERPINA10
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10
chr4_-_40516567 0.062 RBM47
RNA binding motif protein 47
chr17_-_202557 0.061 RPH3AL
rabphilin 3A-like (without C2 domains)
chr6_+_29274402 0.060 NM_030946
OR14J1
olfactory receptor, family 14, subfamily J, member 1
chr9_+_130860769 0.060 SLC25A25
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25
chr5_-_139726173 0.059 NM_001945
HBEGF
heparin-binding EGF-like growth factor
chr14_-_20801427 0.058 NM_021178
NM_182849
CCNB1IP1

cyclin B1 interacting protein 1, E3 ubiquitin protein ligase

chr11_-_5706186 0.058 NM_033034
NM_033092
NM_033093
TRIM5


tripartite motif containing 5


chr3_+_183948216 0.058 NM_138345
VWA5B2
von Willebrand factor A domain containing 5B2
chr19_-_48389571 0.057 NM_003167
SULT2A1
sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1
chr5_+_40841296 0.057 NM_032587
CARD6
caspase recruitment domain family, member 6
chr3_-_164796275 0.056 NM_001041
SI
sucrase-isomaltase (alpha-glucosidase)
chrX_+_1401570 0.056 NM_001161530
NM_172247
CSF2RA

colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)

chr6_-_29455678 0.056 NM_052967
MAS1L
MAS1 oncogene-like
chr3_-_126327397 0.056 NM_001039783
TXNRD3NB
thioredoxin reductase 3 neighbor
chr6_+_158733691 0.055 NM_001007466
NM_020245
TULP4

tubby like protein 4

chrY_+_1351570 0.055 NM_001161530
NM_172247
CSF2RA

colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)

chr4_+_86699858 0.054 ARHGAP24
Rho GTPase activating protein 24
chr7_-_83270746 0.054 NM_001178129
SEMA3E
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E
chr6_-_32557431 0.054 NM_001243965
NM_002124
HLA-DRB1

HLA-DRB4
HLA-DRB5
major histocompatibility complex, class II, DR beta 1

major histocompatibility complex, class II, DR beta 4
major histocompatibility complex, class II, DR beta 5
chr13_-_70682458 0.053 NM_020866
KLHL1
kelch-like 1 (Drosophila)
chr7_+_114066554 0.052 NM_001172767
NM_148899
FOXP2

forkhead box P2

chr16_-_57836380 0.051 NM_001130100
NM_005550
KIFC3

kinesin family member C3

chrX_+_115301957 0.051 NM_000686
AGTR2
angiotensin II receptor, type 2
chr6_-_52628272 0.051 NM_000846
GSTA2
glutathione S-transferase alpha 2
chr1_-_114430168 0.050 NM_001010922
BCL2L15
BCL2-like 15
chr2_+_234621637 0.050 NM_019078
UGT1A5
UDP glucuronosyltransferase 1 family, polypeptide A5
chr7_+_130126035 0.050 NM_177524
MEST
mesoderm specific transcript homolog (mouse)
chr7_-_156801980 0.048 NM_001165255
MNX1
motor neuron and pancreas homeobox 1
chr17_-_202617 0.048 NM_001190411
NM_001190412
NM_001190413
NM_006987
RPH3AL



rabphilin 3A-like (without C2 domains)



chr9_-_21385258 0.047 NM_000605
IFNA2
interferon, alpha 2
chr12_-_102874299 0.047 IGF1
insulin-like growth factor 1 (somatomedin C)
chr13_+_43355685 0.046 NM_182508
C13orf30
chromosome 13 open reading frame 30
chr12_-_24102563 0.046 NM_006940
SOX5
SRY (sex determining region Y)-box 5
chr15_+_59903980 0.045 NM_004751
GCNT3
glucosaminyl (N-acetyl) transferase 3, mucin type
chr7_-_107880492 0.045 NM_001037132
NRCAM
neuronal cell adhesion molecule
chr14_+_96846021 0.045 NM_016472
C14orf129
chromosome 14 open reading frame 129
chr9_-_28719302 0.044 NM_152570
LINGO2
leucine rich repeat and Ig domain containing 2
chr12_-_68553322 0.043 NM_000619
IFNG
interferon, gamma
chr16_-_72206023 0.043 NM_031293
PMFBP1
polyamine modulated factor 1 binding protein 1
chr11_+_71900601 0.043 NM_016724
NM_016725
FOLR1

folate receptor 1 (adult)

chr11_-_104827421 0.043 NM_033306
CASP4
caspase 4, apoptosis-related cysteine peptidase
chr16_+_57728711 0.041 NM_032269
CCDC135
coiled-coil domain containing 135
chr5_+_176513819 0.040 NM_002011
NM_213647
FGFR4

fibroblast growth factor receptor 4

chr6_+_132859426 0.040 NM_175057
TAAR9
trace amine associated receptor 9 (gene/pseudogene)
chr9_-_215892 0.040 NM_152569
C9orf66
chromosome 9 open reading frame 66
chrX_+_70435048 0.040 NM_001097642
GJB1
gap junction protein, beta 1, 32kDa
chr4_-_153273683 0.040 NM_018315
FBXW7
F-box and WD repeat domain containing 7
chr1_+_109255555 0.040 NM_001144937
FNDC7
fibronectin type III domain containing 7
chr16_-_57836370 0.040 KIFC3
kinesin family member C3

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
8.80 3.00e-11 GO:0006805 xenobiotic metabolic process
8.80 3.00e-11 GO:0071466 cellular response to xenobiotic stimulus
8.74 3.50e-11 GO:0009410 response to xenobiotic stimulus
5.60 7.99e-08 GO:0008202 steroid metabolic process
2.87 6.49e-05 GO:0006082 organic acid metabolic process
3.40 2.30e-04 GO:0071702 organic substance transport
1.86 2.51e-04 GO:0042221 response to chemical stimulus
30.97 2.59e-04 GO:0009812 flavonoid metabolic process
3.79 4.42e-04 GO:0032787 monocarboxylic acid metabolic process
25.34 9.22e-04 GO:0009698 phenylpropanoid metabolic process
2.67 1.23e-03 GO:0019752 carboxylic acid metabolic process
2.67 1.23e-03 GO:0043436 oxoacid metabolic process
37.16 1.80e-03 GO:0034391 regulation of smooth muscle cell apoptosis
2.61 1.94e-03 GO:0042180 cellular ketone metabolic process
2.33 2.36e-03 GO:0006629 lipid metabolic process
55.74 6.97e-03 GO:0034392 negative regulation of smooth muscle cell apoptosis
17.42 8.10e-03 GO:0015721 bile acid and bile salt transport
24.77 1.45e-02 GO:0051918 negative regulation of fibrinolysis
2.18 2.72e-02 GO:0070887 cellular response to chemical stimulus
1.34 3.19e-02 GO:0050896 response to stimulus
4.58 3.59e-02 GO:0006820 anion transport
20.27 3.69e-02 GO:0010660 regulation of muscle cell apoptosis
4.45 4.72e-02 GO:0031016 pancreas development

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
2.47 2.99e-04 GO:0005615 extracellular space
4.65 3.89e-04 GO:0016324 apical plasma membrane
1.78 4.00e-04 GO:0044459 plasma membrane part
2.19 8.37e-04 GO:0044421 extracellular region part
1.73 3.37e-03 GO:0005576 extracellular region
8.30 3.59e-03 GO:0031093 platelet alpha granule lumen
8.13 4.14e-03 GO:0034774 secretory granule lumen
3.70 5.35e-03 GO:0045177 apical part of cell
7.81 5.45e-03 GO:0060205 cytoplasmic membrane-bounded vesicle lumen
7.51 7.08e-03 GO:0031983 vesicle lumen
6.85 1.30e-02 GO:0031091 platelet alpha granule
3.34 1.65e-02 GO:0005792 microsome
1.34 1.65e-02 GO:0031224 intrinsic to membrane
4.39 1.84e-02 GO:0031225 anchored to membrane
3.23 2.36e-02 GO:0042598 vesicular fraction
7.43 2.72e-02 GO:0005903 brush border
9.61 2.85e-02 GO:0031526 brush border membrane
23.89 3.63e-02 GO:0005577 fibrinogen complex
1.29 3.69e-02 GO:0044425 membrane part
2.20 3.73e-02 GO:0005789 endoplasmic reticulum membrane

Gene overrepresentation in function category:

enrichment   p-value GO term description
17.92 2.46e-07 GO:0015020 glucuronosyltransferase activity
5.20 2.52e-03 GO:0008194 UDP-glycosyltransferase activity
20.27 8.64e-03 GO:0001972 retinoic acid binding
6.97 1.72e-02 GO:0033293 monocarboxylic acid binding
3.89 1.84e-02 GO:0016758 transferase activity, transferring hexosyl groups
2.75 3.10e-02 GO:0030246 carbohydrate binding
7.60 3.58e-02 GO:0043498 cell surface binding
3.20 3.83e-02 GO:0016757 transferase activity, transferring glycosyl groups
7.43 4.07e-02 GO:0015103 inorganic anion transmembrane transporter activity