Motif ID: HNF4A_NR2F1,2.p2

Z-value: 2.793


Transcription factors associated with HNF4A_NR2F1,2.p2:

Gene SymbolEntrez IDGene Name
HNF4A 3172 hepatocyte nuclear factor 4, alpha
NR2F1 7025 nuclear receptor subfamily 2, group F, member 1
NR2F2 7026 nuclear receptor subfamily 2, group F, member 2

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
NR2F2chr15_+_96876568-0.977.0e-05Click!
NR2F1chr5_+_92918924-0.902.6e-03Click!
HNF4Achr20_+_430300050.866.6e-03Click!


Activity profile for motif HNF4A_NR2F1,2.p2.

activity profile for motif HNF4A_NR2F1,2.p2


Sorted Z-values histogram for motif HNF4A_NR2F1,2.p2

Sorted Z-values for motif HNF4A_NR2F1,2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of HNF4A_NR2F1,2.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr15_+_43885251 7.766 NM_020990
 CKMT1B
CKMT1A
creatine kinase, mitochondrial 1B
creatine kinase, mitochondrial 1A
chr2_+_95940220 3.772 PROM2
prominin 2
chr15_+_43985083 3.719 NM_001015001
 CKMT1A
creatine kinase, mitochondrial 1A
chr2_+_95940195 3.597 NM_001165977
NM_001165978
NM_144707
 PROM2


prominin 2


chr19_+_751108 3.379 NM_173481
 C19orf21
chromosome 19 open reading frame 21
chr4_-_53617781 3.121 NM_001242690
NM_024534
 ERVMER34-1

endogenous retrovirus group MER34, member 1

chr1_+_44064509 2.944 PTPRF
protein tyrosine phosphatase, receptor type, F
chr2_-_238499317 2.883 RAB17
RAB17, member RAS oncogene family
chr6_+_125475334 2.845 NM_001003395
 TPD52L1
tumor protein D52-like 1
chr12_-_54779482 2.707 ZNF385A
zinc finger protein 385A
chr2_-_238499713 2.616 NM_022449
 RAB17
RAB17, member RAS oncogene family
chr14_-_94855120 2.573 NM_000295
 SERPINA1
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
chr4_-_10023094 2.533 NM_020041
 SLC2A9
solute carrier family 2 (facilitated glucose transporter), member 9
chr6_+_150464156 2.464 NM_030949
 PPP1R14C
protein phosphatase 1, regulatory (inhibitor) subunit 14C
chr3_-_189840225 2.388 NM_001134418
 LEPREL1
leprecan-like 1
chr14_-_92333856 2.388 NM_001128596
 TC2N
tandem C2 domains, nuclear
chr1_+_156030965 2.284 NM_020387
 RAB25
RAB25, member RAS oncogene family
chr8_+_21916858 2.267 EPB49
erythrocyte membrane protein band 4.9 (dematin)
chr19_-_6720585 2.189 NM_000064
 C3
complement component 3
chr16_+_3115312 2.154 NM_001012631
NM_001012633
NM_001012718
NM_004221
 IL32



interleukin 32




Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 3 of 3 entries
enrichment   p-value GO term description
1.28 1.12e-02 GO:0044281 small molecule metabolic process
1.25 1.78e-02 GO:0065008 regulation of biological quality
1.09 1.08e-05 GO:0009987 cellular process

Gene overrepresentation in compartment category:

Showing 1 to 18 of 18 entries
enrichment   p-value GO term description
3.81 3.64e-02 GO:0030057 desmosome
1.65 4.03e-02 GO:0005759 mitochondrial matrix
1.53 7.60e-03 GO:0005740 mitochondrial envelope
1.51 2.18e-04 GO:0044429 mitochondrial part
1.51 1.97e-02 GO:0031966 mitochondrial membrane
1.45 5.06e-04 GO:0005624 membrane fraction
1.44 5.41e-04 GO:0005626 insoluble fraction
1.43 5.29e-03 GO:0031967 organelle envelope
1.42 8.29e-03 GO:0031975 envelope
1.41 6.89e-05 GO:0000267 cell fraction
1.29 1.69e-02 GO:0031226 intrinsic to plasma membrane
1.29 2.05e-02 GO:0005887 integral to plasma membrane
1.28 2.94e-02 GO:0005739 mitochondrion
1.23 4.63e-03 GO:0044459 plasma membrane part
1.22 2.17e-02 GO:0031090 organelle membrane
1.14 2.43e-04 GO:0044444 cytoplasmic part
1.10 5.29e-04 GO:0005737 cytoplasm
1.09 4.60e-02 GO:0016020 membrane

Gene overrepresentation in function category:

Showing 1 to 1 of 1 entries
enrichment   p-value GO term description
3.62 2.38e-02 GO:0070330 aromatase activity