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Motif ID: HSF1,2.p2

Z-value: 1.296

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr1_-_242612757	2.086	NM_001195811 NM_001195812	PLD5	phospholipase D family, member 5
chr17_-_56494889	1.386		RNF43	ring finger protein 43
chr17_-_56494930	1.227	NM_017763	RNF43	ring finger protein 43
chr10_-_116444112	1.198		ABLIM1	actin binding LIM protein 1
chr2_-_113542970	1.182	NM_000575	IL1A	interleukin 1, alpha
chr10_-_116444374	1.081	NM_001003407 NM_001003408	ABLIM1	actin binding LIM protein 1
chr19_-_49567123	0.907	NM_006179	NTF4	neurotrophin 4
chr12_+_105153258	0.874		CHST11	carbohydrate (chondroitin 4) sulfotransferase 11
chr5_+_36608430	0.859	NM_001166695	SLC1A3	solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr3_-_57113292	0.805	NM_001128615	ARHGEF3	Rho guanine nucleotide exchange factor (GEF) 3
chr12_-_123201319	0.787	NM_006018	HCAR3	hydroxycarboxylic acid receptor 3
chr7_-_83824216	0.763	NM_006080	SEMA3A	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr19_+_35607218	0.752		FXYD3	FXYD domain containing ion transport regulator 3
chr12_-_123187842	0.743	NM_177551	HCAR2	hydroxycarboxylic acid receptor 2
chr12_-_52914080	0.732	NM_000424	KRT5	keratin 5
chr8_+_86376130	0.719	NM_000067	CA2	carbonic anhydrase II
chr18_+_21452981	0.719	NM_000227 NM_001127718	LAMA3	laminin, alpha 3
chr2_+_162272892	0.704		TBR1	T-box, brain, 1
chr18_-_47376156	0.699		MYO5B	myosin VB
chr8_-_125580745	0.696		MTSS1	metastasis suppressor 1
chr1_-_207205996	0.688	NM_001083924 NM_023938	C1orf116	chromosome 1 open reading frame 116
chr4_+_41258895	0.656	NM_004181	UCHL1	ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
chr4_+_77356252	0.654	NM_020859	SHROOM3	shroom family member 3
chr12_-_8815266	0.647		MFAP5	microfibrillar associated protein 5
chr3_+_127641901	0.645	NM_207335	KBTBD12	kelch repeat and BTB (POZ) domain containing 12
chr19_+_35606731	0.645	NM_001136007 NM_001136008 NM_001136009 NM_001136010 NM_001136011 NM_001136012 NM_005971 NM_021910	FXYD3	FXYD domain containing ion transport regulator 3
chr17_-_27401793	0.641		TIAF1	TGFB1-induced anti-apoptotic factor 1
chr2_-_113594325	0.631	NM_000576	IL1B	interleukin 1, beta
chr19_-_42947050	0.620	NM_198477	CXCL17	chemokine (C-X-C motif) ligand 17
chr8_-_15095791	0.616	NM_139167	SGCZ	sarcoglycan, zeta
chr4_+_41258909	0.616		UCHL1	ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
chr11_+_12308446	0.609	NM_032867	MICALCL	MICAL C-terminal like
chr8_-_142238672	0.603	NM_001080431	SLC45A4	solute carrier family 45, member 4
chr2_+_102979096	0.591	NM_003855	IL18R1	interleukin 18 receptor 1
chr3_+_122044010	0.574	NM_005213	CSTA	cystatin A (stefin A)
chr1_+_233749749	0.566	NM_002245	KCNK1	potassium channel, subfamily K, member 1
chrX_-_31526414	0.566	NM_004014	DMD	dystrophin
chrX_-_33229428	0.553	NM_004006	DMD	dystrophin
chr4_+_41258941	0.552		UCHL1	ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
chr11_+_1855673	0.547	NM_138567	SYT8	synaptotagmin VIII
chr8_+_32579350	0.544	NM_001159996	NRG1	neuregulin 1
chr11_+_34654010	0.542	NM_001206616	EHF	ets homologous factor
chr4_-_122302112	0.532	NM_198179	QRFPR	pyroglutamylated RFamide peptide receptor
chr2_+_207804277	0.529	NM_173077	CPO	carboxypeptidase O
chr5_+_68800003	0.511	NM_001205255	OCLN	occludin
chr16_+_3115638	0.486	NM_001012634	IL32	interleukin 32
chr19_-_51456159	0.483	NM_001077491 NM_001077492 NM_012427	KLK5	kallikrein-related peptidase 5
chr6_+_106534188	0.473	NM_001198	PRDM1	PR domain containing 1, with ZNF domain
chr11_+_121322848	0.472	NM_003105	SORL1	sortilin-related receptor, L(DLR class) A repeats containing
chr10_-_14816895	0.465	NM_031453	FAM107B	family with sequence similarity 107, member B
chr8_-_110620220	0.463		SYBU	syntabulin (syntaxin-interacting)
chr5_+_140254930	0.455	NM_018903 NM_031864	PCDHA12	protocadherin alpha 12
chr16_+_3115312	0.452	NM_001012631 NM_001012633 NM_001012718 NM_004221	IL32	interleukin 32
chr6_+_47666288	0.446	NM_153838	GPR115	G protein-coupled receptor 115
chr8_-_22550057	0.445	NM_001199881	EGR3	early growth response 3
chr16_+_3115641	0.443	NM_001012632 NM_001012636	IL32	interleukin 32
chr16_+_3115611	0.442	NM_001012635	IL32	interleukin 32
chr20_+_9198036	0.431	NM_182797	PLCB4	phospholipase C, beta 4
chr6_+_14117486	0.422	NM_001251901	CD83	CD83 molecule
chr11_-_104905849	0.420		CASP1	caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase)
chr6_+_29913400	0.417
chr10_+_75673346	0.416		PLAU	plasminogen activator, urokinase
chr16_-_31147062	0.415	NM_002773	PRSS8	protease, serine, 8
chr9_-_97090903	0.403	NM_017561	FAM22F	family with sequence similarity 22, member F
chr6_-_53013581	0.402	NM_003643	GCM1	glial cells missing homolog 1 (Drosophila)
chrX_-_32430370	0.393	NM_004011 NM_004012	DMD	dystrophin
chr17_-_27402626	0.392	NM_004740	TIAF1	TGFB1-induced anti-apoptotic factor 1
chr1_-_184006828	0.392	NM_015101	GLT25D2	glycosyltransferase 25 domain containing 2
chr16_+_3115639	0.391		IL32	interleukin 32
chr5_+_140213968	0.385	NM_018910 NM_031852	PCDHA7	protocadherin alpha 7
chr1_+_233749917	0.380		KCNK1	potassium channel, subfamily K, member 1
chrX_+_107288199	0.373	NM_001170553 NM_182607	VSIG1	V-set and immunoglobulin domain containing 1
chr12_-_14720553	0.373		PLBD1	phospholipase B domain containing 1
chr6_+_13924676	0.370	NM_001165034	RNF182	ring finger protein 182
chr8_-_22550708	0.369	NM_004430	EGR3	early growth response 3
chr11_+_6897855	0.366	NM_207186	OR10A4	olfactory receptor, family 10, subfamily A, member 4
chr5_-_148442606	0.363	NM_024577	SH3TC2	SH3 domain and tetratricopeptide repeats 2
chr1_-_159923961	0.357	NM_001146172 NM_001146173 NM_033438	SLAMF9	SLAM family member 9
chr19_-_6720585	0.356	NM_000064	C3	complement component 3
chr12_+_2904101	0.353	NM_002014	FKBP4	FK506 binding protein 4, 59kDa
chr17_-_74483806	0.351	NM_001005498	RHBDF2	rhomboid 5 homolog 2 (Drosophila)
chr17_-_39661803	0.349	NM_002274 NM_153490	KRT13	keratin 13
chr6_-_39197225	0.349	NM_003740	KCNK5	potassium channel, subfamily K, member 5
chr6_-_105627857	0.348	NM_022361	POPDC3	popeye domain containing 3
chr4_+_76481257	0.345	NM_001206981 NM_178497	C4orf26	chromosome 4 open reading frame 26
chr11_-_118134956	0.341		MPZL2	myelin protein zero-like 2
chr19_+_14142261	0.340	NM_004843	IL27RA	interleukin 27 receptor, alpha
chr19_+_2289996	0.340
chr12_-_7281374	0.340	NM_031491	RBP5	retinol binding protein 5, cellular
chr12_-_14720790	0.340	NM_024829	PLBD1	phospholipase B domain containing 1
chr3_-_129599220	0.335	NM_001017395	TMCC1	transmembrane and coiled-coil domain family 1
chr1_-_12677347	0.334	NM_004753	DHRS3	dehydrogenase/reductase (SDR family) member 3
chrX_-_15683153	0.333	NM_020665	TMEM27	transmembrane protein 27
chr8_-_81083660	0.333	NM_001025253 NM_005079	TPD52	tumor protein D52
chr16_-_31146992	0.328		PRSS8	protease, serine, 8
chr11_-_118134986	0.325		MPZL2	myelin protein zero-like 2
chr19_+_54372659	0.321	NM_001020821 NM_001020818	MYADM	myeloid-associated differentiation marker
chr17_+_56315786	0.320	NM_001160102 NM_006151	LPO	lactoperoxidase
chr6_-_33041266	0.316	NM_033554	HLA-DPA1	major histocompatibility complex, class II, DP alpha 1
chr18_+_55862577	0.316	NM_001144970	NEDD4L	neural precursor cell expressed, developmentally down-regulated 4-like
chr1_+_202183282	0.315	NM_001017404	LGR6	leucine-rich repeat containing G protein-coupled receptor 6
chr17_+_1646129	0.315	NM_000934 NM_001165921	SERPINF2	serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2
chr3_-_123411185	0.315		MYLK	myosin light chain kinase
chr7_+_1127722	0.313	NM_001098201	GPER	G protein-coupled estrogen receptor 1
chr19_-_14629235	0.312
chr5_+_140247767	0.311	NM_018902 NM_031861	PCDHA11	protocadherin alpha 11
chr12_-_52845862	0.310	NM_005555	KRT6B	keratin 6B
chr17_-_39093671	0.308	NM_015515	KRT23	keratin 23 (histone deacetylase inducible)
chr1_+_117452359	0.308	NM_020440	PTGFRN	prostaglandin F2 receptor negative regulator
chr16_-_58328879	0.307	NM_001080492	PRSS54	protease, serine, 54
chr3_+_142375738	0.306	NM_001172312	PLS1	plastin 1
chr7_+_18548899	0.304	NM_001204147 NM_001204148	HDAC9	histone deacetylase 9
chr7_+_129984629	0.302	NM_001127441 NM_001127442 NM_080385	CPA5	carboxypeptidase A5
chr2_-_165424993	0.301		GRB14	growth factor receptor-bound protein 14
chrX_-_153141398	0.297	NM_000425 NM_001143963 NM_024003	L1CAM	L1 cell adhesion molecule
chr3_-_9290592	0.295		SRGAP3	SLIT-ROBO Rho GTPase activating protein 3
chr7_-_134896166	0.295		WDR91	WD repeat domain 91
chrY_-_20935503	0.294	NM_001001877 NM_153716 NM_152584 NM_033108	HSFY2 HSFY1	heat shock transcription factor, Y linked 2 heat shock transcription factor, Y-linked 1
chr20_+_43803539	0.293	NM_002638	PI3	peptidase inhibitor 3, skin-derived
chr19_-_14629227	0.290		DNAJB1	DnaJ (Hsp40) homolog, subfamily B, member 1
chr6_+_27215479	0.290	NM_005865	PRSS16	protease, serine, 16 (thymus)
chr3_+_130612806	0.288	NM_001199179 NM_001001485 NM_001199183 NM_001199184 NM_001199185 NM_014382 NM_001001486 NM_001001487	ATP2C1	ATPase, Ca++ transporting, type 2C, member 1
chr19_-_14629160	0.287	NM_006145	DNAJB1	DnaJ (Hsp40) homolog, subfamily B, member 1
chr11_+_69061599	0.285	NM_138768	MYEOV	myeloma overexpressed (in a subset of t(11;14) positive multiple myelomas)
chr3_-_48471401	0.284	NM_001130082	PLXNB1	plexin B1
chr17_-_27401216	0.282		TIAF1	TGFB1-induced anti-apoptotic factor 1
chr15_+_40509628	0.282	NM_001128628 NM_001128629	PAK6	p21 protein (Cdc42/Rac)-activated kinase 6
chr5_+_147582338	0.273	NM_001195290 NM_205841	SPINK6	serine peptidase inhibitor, Kazal type 6
chr4_+_30722445	0.273		PCDH7	protocadherin 7
chr18_-_28742744	0.273	NM_004948 NM_024421	DSC1	desmocollin 1
chr22_+_32439018	0.272	NM_000343	SLC5A1	solute carrier family 5 (sodium/glucose cotransporter), member 1
chr18_+_61420276	0.272	NM_001040147	SERPINB7	serpin peptidase inhibitor, clade B (ovalbumin), member 7
chr19_+_14142572	0.271		IL27RA	interleukin 27 receptor, alpha
chr2_-_142889269	0.269	NM_018557	LRP1B	low density lipoprotein receptor-related protein 1B
chr6_+_29364331	0.269	NM_013936	OR12D2	olfactory receptor, family 12, subfamily D, member 2
chr17_-_46608271	0.267	NM_002144	HOXB1	homeobox B1
chr6_+_29274402	0.264	NM_030946	OR14J1	olfactory receptor, family 14, subfamily J, member 1
chr8_-_75233461	0.263	NM_020647	JPH1	junctophilin 1
chr15_+_75491232	0.263		C15orf39	chromosome 15 open reading frame 39
chr5_+_147443534	0.262	NM_001127698 NM_001127699 NM_006846	SPINK5	serine peptidase inhibitor, Kazal type 5
chr3_+_136537860	0.261	NM_001097599 NM_001097600 NM_025246	TMEM22	transmembrane protein 22
chr11_-_119599253	0.260	NM_002855 NM_203285 NM_203286	PVRL1	poliovirus receptor-related 1 (herpesvirus entry mediator C)
chr12_+_11802726	0.258	NM_001987	ETV6	ets variant 6
chr22_-_27014037	0.255		CRYBB1	crystallin, beta B1
chr19_+_14142459	0.254		IL27RA	interleukin 27 receptor, alpha
chr2_+_26915390	0.253	NM_002246	KCNK3	potassium channel, subfamily K, member 3
chr6_-_117086812	0.251	NM_001085480	FAM162B	family with sequence similarity 162, member B
chr11_-_114466471	0.251	NM_001077639 NM_017678	FAM55D	family with sequence similarity 55, member D
chr18_+_55711890	0.249		NEDD4L	neural precursor cell expressed, developmentally down-regulated 4-like
chr7_+_26331611	0.248		SNX10	sorting nexin 10
chr7_-_134896257	0.247		WDR91	WD repeat domain 91
chr12_-_85306539	0.246		SLC6A15	solute carrier family 6 (neutral amino acid transporter), member 15
chr11_-_89956531	0.244	NM_001144073 NM_012124	CHORDC1	cysteine and histidine-rich domain (CHORD) containing 1
chrX_-_51239295	0.242		NUDT11	nudix (nucleoside diphosphate linked moiety X)-type motif 11
chr8_+_75736771	0.241	NM_015886	PI15	peptidase inhibitor 15
chrX_-_24690740	0.240	NM_001163264	PCYT1B	phosphate cytidylyltransferase 1, choline, beta
chr7_-_134896251	0.237		WDR91	WD repeat domain 91
chr19_-_33360641	0.237	NM_001126335 NM_001243036 NM_014270	SLC7A9	solute carrier family 7 (glycoprotein-associated amino acid transporter light chain, bo,+ system), member 9
chr11_-_66488712	0.236	NM_006946	SPTBN2	spectrin, beta, non-erythrocytic 2
chr3_-_165555252	0.235	NM_000055	BCHE	butyrylcholinesterase
chr19_+_14142611	0.234		IL27RA	interleukin 27 receptor, alpha
chrX_-_154563735	0.233	NM_001289	CLIC2	chloride intracellular channel 2
chrX_-_8700170	0.231	NM_000216	KAL1	Kallmann syndrome 1 sequence
chr22_-_25758523	0.230	NM_182492	LRP5L	low density lipoprotein receptor-related protein 5-like
chr17_-_27401590	0.229		TIAF1	TGFB1-induced anti-apoptotic factor 1
chr12_+_11802905	0.228		ETV6	ets variant 6
chr11_+_10471867	0.228	NM_001172431	AMPD3	adenosine monophosphate deaminase 3
chr12_-_85306569	0.228		SLC6A15	solute carrier family 6 (neutral amino acid transporter), member 15
chr8_-_80993009	0.227	NM_001025252	TPD52	tumor protein D52
chr10_+_82173574	0.226	NM_001243778 NM_001243782	C10orf58	chromosome 10 open reading frame 58
chr22_-_27013959	0.226	NM_001887	CRYBB1	crystallin, beta B1
chr2_+_113816684	0.225	NM_012275	IL36RN	interleukin 36 receptor antagonist
chr9_-_124990949	0.225	NM_014368 NM_199160	LHX6	LIM homeobox 6
chr2_+_113816214	0.225	NM_173170	IL36RN	interleukin 36 receptor antagonist
chr12_+_119772516	0.224	NM_178499	CCDC60	coiled-coil domain containing 60
chr7_+_26331493	0.224	NM_001199835 NM_013322	SNX10	sorting nexin 10
chr7_-_139763520	0.222	NM_022750	PARP12	poly (ADP-ribose) polymerase family, member 12
chr3_-_165555167	0.222		BCHE	butyrylcholinesterase
chr7_+_39017608	0.221	NM_001166018 NM_007252	POU6F2	POU class 6 homeobox 2
chrX_-_51239426	0.220	NM_018159	NUDT11	nudix (nucleoside diphosphate linked moiety X)-type motif 11
chr7_-_134896268	0.219	NM_014149	WDR91	WD repeat domain 91
chr11_-_5462782	0.219	NM_001005288	OR51I1	olfactory receptor, family 51, subfamily I, member 1
chr10_-_62332666	0.219	NM_001204404	ANK3	ankyrin 3, node of Ranvier (ankyrin G)
chr7_-_75443026	0.218	NM_002991	CCL24	chemokine (C-C motif) ligand 24
chr8_-_144810691	0.216		FAM83H	family with sequence similarity 83, member H
chr14_-_75330535	0.216	NM_001080408 NM_001243007	PROX2	prospero homeobox 2
chr3_-_196756572	0.216		MFI2	antigen p97 (melanoma associated) identified by monoclonal antibodies 133.2 and 96.5
chr3_-_184079266	0.214	NM_001171087 NM_001171088 NM_001171089 NM_004366	CLCN2	chloride channel 2
chr11_-_7847518	0.210	NM_153445	OR5P3	olfactory receptor, family 5, subfamily P, member 3
chr11_+_124933007	0.209	NM_001145290 NM_198277	SLC37A2	solute carrier family 37 (glycerol-3-phosphate transporter), member 2
chr7_-_36406446	0.208	NM_001199707 NM_001199706 NM_015314 NM_001199708	KIAA0895	KIAA0895
chr11_+_117947726	0.206	NM_001083947 NM_001173551 NM_001173552 NM_019894	TMPRSS4	transmembrane protease, serine 4
chr18_-_53068755	0.205		TCF4	transcription factor 4
chr3_+_193853937	0.204		HES1	hairy and enhancer of split 1, (Drosophila)
chr15_+_68924326	0.204	NM_001190457	CORO2B	coronin, actin binding protein, 2B
chr12_-_85306579	0.204	NM_001146335 NM_018057 NM_182767	SLC6A15	solute carrier family 6 (neutral amino acid transporter), member 15
chr22_+_31608284	0.203		LIMK2	LIM domain kinase 2
chr12_-_54779482	0.203		ZNF385A	zinc finger protein 385A
chrX_+_115301957	0.203	NM_000686	AGTR2	angiotensin II receptor, type 2
chr11_-_118135197	0.203	NM_005797 NM_144765	MPZL2	myelin protein zero-like 2

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.65	1.21e-05	GO:0040011	locomotion
1.29	1.30e-05	GO:0007275	multicellular organismal development
1.26	3.18e-05	GO:0032502	developmental process
1.49	5.66e-05	GO:0051239	regulation of multicellular organismal process
1.31	7.92e-05	GO:0048731	system development
1.29	8.03e-05	GO:0048856	anatomical structure development
1.64	1.49e-04	GO:2000026	regulation of multicellular organismal development
7.93	1.87e-04	GO:0060600	dichotomous subdivision of an epithelial terminal unit
1.74	3.60e-04	GO:0006928	cellular component movement
1.09	7.97e-04	GO:0009987	cellular process
1.33	1.53e-03	GO:0048869	cellular developmental process
1.76	1.98e-03	GO:0048870	cell motility
1.76	1.98e-03	GO:0051674	localization of cell
8.48	2.84e-03	GO:0060678	dichotomous subdivision of terminal units involved in ureteric bud branching
1.32	3.30e-03	GO:0030154	cell differentiation
1.17	4.51e-03	GO:0032501	multicellular organismal process
5.82	1.16e-02	GO:0030513	positive regulation of BMP signaling pathway
5.82	1.16e-02	GO:0048484	enteric nervous system development
7.54	1.16e-02	GO:0048880	sensory system development
7.54	1.16e-02	GO:0048892	lateral line nerve development
7.54	1.16e-02	GO:0048895	lateral line nerve glial cell differentiation
7.54	1.16e-02	GO:0048925	lateral line system development
7.54	1.16e-02	GO:0048937	lateral line nerve glial cell development
7.54	1.16e-02	GO:0050935	iridophore differentiation
1.74	1.35e-02	GO:0016477	cell migration
6.46	1.36e-02	GO:0090184	positive regulation of kidney development
1.36	1.45e-02	GO:0009653	anatomical structure morphogenesis
1.48	1.51e-02	GO:0050793	regulation of developmental process
1.31	2.84e-02	GO:0048513	organ development
1.78	3.07e-02	GO:0051240	positive regulation of multicellular organismal process
1.47	3.15e-02	GO:0009888	tissue development
1.62	3.89e-02	GO:0006935	chemotaxis
1.62	3.89e-02	GO:0042330	taxis
1.66	4.72e-02	GO:0051094	positive regulation of developmental process
4.27	4.90e-02	GO:0001755	neural crest cell migration
1.27	4.98e-02	GO:0042221	response to chemical stimulus

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.13	3.45e-04	GO:0016020	membrane
1.17	6.07e-04	GO:0031224	intrinsic to membrane
1.17	6.81e-04	GO:0016021	integral to membrane
1.41	1.03e-03	GO:0005887	integral to plasma membrane
1.29	1.44e-03	GO:0044459	plasma membrane part
1.38	3.18e-03	GO:0031226	intrinsic to plasma membrane
1.13	5.89e-03	GO:0044425	membrane part
1.18	7.60e-03	GO:0071944	cell periphery
1.18	9.51e-03	GO:0005886	plasma membrane
1.65	2.52e-02	GO:0009986	cell surface

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
2.02	1.10e-02	GO:0005244	voltage-gated ion channel activity
2.02	1.10e-02	GO:0022832	voltage-gated channel activity
4.62	1.24e-02	GO:0015026	coreceptor activity
2.32	1.86e-02	GO:0051082	unfolded protein binding