Motif ID: HSF1,2.p2

Z-value: 1.296


Transcription factors associated with HSF1,2.p2:

Gene SymbolEntrez IDGene Name
HSF1 3297 heat shock transcription factor 1
HSF2 3298 heat shock transcription factor 2

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
HSF1chr8_+_1455152850.353.9e-01Click!
HSF2chr6_+_122720750-0.245.7e-01Click!


Activity profile for motif HSF1,2.p2.

activity profile for motif HSF1,2.p2


Sorted Z-values histogram for motif HSF1,2.p2

Sorted Z-values for motif HSF1,2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of HSF1,2.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr1_-_242612757 2.086 NM_001195811
NM_001195812
 PLD5

phospholipase D family, member 5

chr17_-_56494889 1.386 RNF43
ring finger protein 43
chr17_-_56494930 1.227 NM_017763
 RNF43
ring finger protein 43
chr10_-_116444112 1.198 ABLIM1
actin binding LIM protein 1
chr2_-_113542970 1.182 NM_000575
 IL1A
interleukin 1, alpha
chr10_-_116444374 1.081 NM_001003407
NM_001003408
 ABLIM1

actin binding LIM protein 1

chr19_-_49567123 0.907 NM_006179
 NTF4
neurotrophin 4
chr12_+_105153258 0.874 CHST11
carbohydrate (chondroitin 4) sulfotransferase 11
chr5_+_36608430 0.859 NM_001166695
 SLC1A3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr3_-_57113292 0.805 NM_001128615
 ARHGEF3
Rho guanine nucleotide exchange factor (GEF) 3
chr12_-_123201319 0.787 NM_006018
 HCAR3
hydroxycarboxylic acid receptor 3
chr7_-_83824216 0.763 NM_006080
 SEMA3A
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr19_+_35607218 0.752 FXYD3
FXYD domain containing ion transport regulator 3
chr12_-_123187842 0.743 NM_177551
 HCAR2
hydroxycarboxylic acid receptor 2
chr12_-_52914080 0.732 NM_000424
 KRT5
keratin 5
chr8_+_86376130 0.719 NM_000067
 CA2
carbonic anhydrase II
chr18_+_21452981 0.719 NM_000227
NM_001127718
 LAMA3

laminin, alpha 3

chr2_+_162272892 0.704 TBR1
T-box, brain, 1
chr18_-_47376156 0.699 MYO5B
myosin VB
chr8_-_125580745 0.696 MTSS1
metastasis suppressor 1

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 36 entries
enrichment   p-value GO term description
8.48 2.84e-03 GO:0060678 dichotomous subdivision of terminal units involved in ureteric bud branching
7.93 1.87e-04 GO:0060600 dichotomous subdivision of an epithelial terminal unit
7.54 1.16e-02 GO:0048880 sensory system development
7.54 1.16e-02 GO:0048892 lateral line nerve development
7.54 1.16e-02 GO:0048895 lateral line nerve glial cell differentiation
7.54 1.16e-02 GO:0048925 lateral line system development
7.54 1.16e-02 GO:0048937 lateral line nerve glial cell development
7.54 1.16e-02 GO:0050935 iridophore differentiation
6.46 1.36e-02 GO:0090184 positive regulation of kidney development
5.82 1.16e-02 GO:0030513 positive regulation of BMP signaling pathway
5.82 1.16e-02 GO:0048484 enteric nervous system development
4.27 4.90e-02 GO:0001755 neural crest cell migration
1.78 3.07e-02 GO:0051240 positive regulation of multicellular organismal process
1.76 1.98e-03 GO:0048870 cell motility
1.76 1.98e-03 GO:0051674 localization of cell
1.74 3.60e-04 GO:0006928 cellular component movement
1.74 1.35e-02 GO:0016477 cell migration
1.66 4.72e-02 GO:0051094 positive regulation of developmental process
1.65 1.21e-05 GO:0040011 locomotion
1.64 1.49e-04 GO:2000026 regulation of multicellular organismal development

Gene overrepresentation in compartment category:

Showing 1 to 10 of 10 entries
enrichment   p-value GO term description
1.65 2.52e-02 GO:0009986 cell surface
1.41 1.03e-03 GO:0005887 integral to plasma membrane
1.38 3.18e-03 GO:0031226 intrinsic to plasma membrane
1.29 1.44e-03 GO:0044459 plasma membrane part
1.18 7.60e-03 GO:0071944 cell periphery
1.18 9.51e-03 GO:0005886 plasma membrane
1.17 6.07e-04 GO:0031224 intrinsic to membrane
1.17 6.81e-04 GO:0016021 integral to membrane
1.13 3.45e-04 GO:0016020 membrane
1.13 5.89e-03 GO:0044425 membrane part

Gene overrepresentation in function category:

Showing 1 to 4 of 4 entries
enrichment   p-value GO term description
4.62 1.24e-02 GO:0015026 coreceptor activity
2.32 1.86e-02 GO:0051082 unfolded protein binding
2.02 1.10e-02 GO:0005244 voltage-gated ion channel activity
2.02 1.10e-02 GO:0022832 voltage-gated channel activity