Motif ID: IKZF1.p2

Z-value: 1.485


Transcription factors associated with IKZF1.p2:

Gene SymbolEntrez IDGene Name
IKZF1 10320 IKAROS family zinc finger 1 (Ikaros)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
IKZF1chr7_+_503482550.811.5e-02Click!


Activity profile for motif IKZF1.p2.

activity profile for motif IKZF1.p2


Sorted Z-values histogram for motif IKZF1.p2

Sorted Z-values for motif IKZF1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of IKZF1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr15_+_41136178 2.766 NM_003710
NM_181642
 SPINT1

serine peptidase inhibitor, Kunitz type 1

chr12_-_58160823 2.420 NM_000785
 CYP27B1
cytochrome P450, family 27, subfamily B, polypeptide 1
chr19_-_51456159 2.144 NM_001077491
NM_001077492
NM_012427
 KLK5


kallikrein-related peptidase 5


chr2_+_47596286 2.041 NM_002354
 EPCAM
epithelial cell adhesion molecule
chr19_-_10697907 1.945 NM_005498
 AP1M2
adaptor-related protein complex 1, mu 2 subunit
chr1_+_26856259 1.859 RPS6KA1
ribosomal protein S6 kinase, 90kDa, polypeptide 1
chr1_+_26856252 1.623 RPS6KA1
ribosomal protein S6 kinase, 90kDa, polypeptide 1
chr1_-_209979388 1.604 NM_001206696
NM_006147
 IRF6

interferon regulatory factor 6

chr19_+_38755097 1.563 NM_001166103
NM_021102
 SPINT2

serine peptidase inhibitor, Kunitz type, 2

chr19_+_38755422 1.540 SPINT2
serine peptidase inhibitor, Kunitz type, 2
chr2_-_113594325 1.513 NM_000576
 IL1B
interleukin 1, beta
chr1_+_26856240 1.468 NM_002953
 RPS6KA1
ribosomal protein S6 kinase, 90kDa, polypeptide 1
chr11_+_62649160 1.452 SLC3A2
solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2
chr19_+_54371170 1.389 MYADM
myeloid-associated differentiation marker
chr1_+_183155173 1.375 NM_005562
NM_018891
 LAMC2

laminin, gamma 2

chr11_+_18287807 1.344 NM_000331
NM_001178006
NM_199161
 SAA1


serum amyloid A1


chr16_-_68269948 1.323 NM_024939
 ESRP2
epithelial splicing regulatory protein 2
chr20_+_44637539 1.309 NM_004994
 MMP9
matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
chr17_-_7493389 1.303 NM_006942
 SOX15
SRY (sex determining region Y)-box 15
chr11_-_18270167 1.279 NM_001199744
NM_001127380
NM_030754
 SAA2-SAA4
SAA2

SAA2-SAA4 readthrough
serum amyloid A2


Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 5 of 5 entries
enrichment   p-value GO term description
1.20 1.38e-02 GO:0023052 signaling
1.18 3.46e-02 GO:0051716 cellular response to stimulus
1.12 1.51e-09 GO:0009987 cellular process
1.12 3.53e-03 GO:0065007 biological regulation
1.12 3.81e-02 GO:0050794 regulation of cellular process

Gene overrepresentation in compartment category:

Showing 1 to 7 of 7 entries
enrichment   p-value GO term description
1.56 1.55e-02 GO:0005730 nucleolus
1.28 1.90e-03 GO:0044459 plasma membrane part
1.28 1.60e-02 GO:0031981 nuclear lumen
1.26 4.78e-03 GO:0070013 intracellular organelle lumen
1.26 5.17e-03 GO:0031974 membrane-enclosed lumen
1.25 6.64e-03 GO:0043233 organelle lumen
1.25 1.94e-02 GO:0044428 nuclear part

Gene overrepresentation in function category:

Showing 1 to 2 of 2 entries
enrichment   p-value GO term description
3.75 4.88e-02 GO:0030551 cyclic nucleotide binding
1.11 2.11e-02 GO:0005515 protein binding