Motif ID: LMO2.p2

Z-value: 0.596


Transcription factors associated with LMO2.p2:

Gene SymbolEntrez IDGene Name
LMO2 4005 LIM domain only 2 (rhombotin-like 1)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
LMO2chr11_-_33913835,
chr11_-_33891361,
chr11_-_33891485,
chr11_-_33891258,
chr11_-_33890931
0.009.9e-01Click!


Activity profile for motif LMO2.p2.

activity profile for motif LMO2.p2


Sorted Z-values histogram for motif LMO2.p2

Sorted Z-values for motif LMO2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of LMO2.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr17_-_39341126 0.737 NM_033060
KRTAP4-1
keratin associated protein 4-1
chr11_-_694842 0.714 DEAF1
deformed epidermal autoregulatory factor 1 (Drosophila)
chr17_-_39280377 0.649 NM_031854
KRTAP4-12
keratin associated protein 4-12
chr9_-_97401588 0.585 FBP1
fructose-1,6-bisphosphatase 1
chr17_+_39382878 0.556 NM_031961
KRTAP9-2
keratin associated protein 9-2
chrX_-_107018889 0.488 TSC22D3
TSC22 domain family, member 3
chr9_-_97401746 0.473 FBP1
fructose-1,6-bisphosphatase 1
chr9_-_97401833 0.448 NM_000507
FBP1
fructose-1,6-bisphosphatase 1
chr17_+_39240412 0.425 NM_033061
KRTAP4-7
keratin associated protein 4-7
chr10_-_103347882 0.411 POLL
polymerase (DNA directed), lambda
chr1_-_85930610 0.403 DDAH1
dimethylarginine dimethylaminohydrolase 1
chr17_-_39316982 0.398 NM_032524
KRTAP4-4
keratin associated protein 4-4
chr22_-_29977325 0.384 NM_003634
NIPSNAP1
nipsnap homolog 1 (C. elegans)
chr12_-_95942570 0.375 NM_001042403
USP44
ubiquitin specific peptidase 44
chr15_+_74218962 0.360 LOXL1
lysyl oxidase-like 1
chr10_-_103347978 0.358 NM_001174084
NM_001174085
NM_013274
POLL


polymerase (DNA directed), lambda


chr11_-_63933493 0.355 NM_014067
MACROD1
MACRO domain containing 1
chr8_+_17433941 0.352 NM_006207
PDGFRL
platelet-derived growth factor receptor-like
chr3_+_49059046 0.351 NM_199069
NM_199070
NDUFAF3

NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 3

chr1_-_153321021 0.334 NM_020393
PGLYRP4
peptidoglycan recognition protein 4
chrX_-_107019001 0.312 NM_198057
TSC22D3
TSC22 domain family, member 3
chr3_+_49059490 0.310 NDUFAF3
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 3
chr10_+_92980322 0.306 NM_032373
PCGF5
polycomb group ring finger 5
chr11_-_63933204 0.305 MACROD1
MACRO domain containing 1
chr3_+_184056304 0.297 FAM131A
family with sequence similarity 131, member A
chr15_+_74218794 0.290 LOXL1
lysyl oxidase-like 1
chr19_+_14544216 0.290 PKN1
protein kinase N1
chr17_-_19648771 0.283 NM_001135168
ALDH3A1
aldehyde dehydrogenase 3 family, member A1
chr15_-_44487237 0.282 NM_032892
FRMD5
FERM domain containing 5
chrX_+_16964730 0.279 NM_001080975
NM_004726
REPS2

RALBP1 associated Eps domain containing 2

chr19_-_18391440 0.278


chr19_-_57183122 0.276 NM_001005850
ZNF835
zinc finger protein 835
chr5_+_148520985 0.274 NM_014945
ABLIM3
actin binding LIM protein family, member 3
chr6_+_35995583 0.271 MAPK14
mitogen-activated protein kinase 14
chr1_-_85930733 0.267 NM_012137
DDAH1
dimethylarginine dimethylaminohydrolase 1
chr3_-_182833859 0.256 MCCC1
methylcrotonoyl-CoA carboxylase 1 (alpha)
chr19_+_47104389 0.249 CALM3
calmodulin 3 (phosphorylase kinase, delta)
chr19_+_47104559 0.246 CALM3
calmodulin 3 (phosphorylase kinase, delta)
chr11_-_695010 0.246 DEAF1
deformed epidermal autoregulatory factor 1 (Drosophila)
chr7_-_44365019 0.238 NM_001220
NM_172078
NM_172079
NM_172080
NM_172081
NM_172082
NM_172083
NM_172084
CAMK2B







calcium/calmodulin-dependent protein kinase II beta







chr17_-_4890664 0.237 NM_001171167
NM_001171168
CAMTA2

calmodulin binding transcription activator 2

chr1_-_1850704 0.235 NM_178545
TMEM52
transmembrane protein 52
chr22_+_32870932 0.233 FBXO7
F-box protein 7
chr19_+_47104490 0.229 NM_005184
CALM3
calmodulin 3 (phosphorylase kinase, delta)
chr17_+_75315590 0.228 NM_006640
SEPT9
septin 9
chr15_-_44487468 0.228 FRMD5
FERM domain containing 5
chr10_+_103348040 0.228 NM_015448
DPCD
deleted in primary ciliary dyskinesia homolog (mouse)
chr12_-_30848744 0.228 IPO8
importin 8
chr2_-_220436010 0.226 OBSL1
obscurin-like 1
chr11_-_34535302 0.225 NM_001243080
NM_001422
ELF5

E74-like factor 5 (ets domain transcription factor)

chr2_-_224702200 0.224 AP1S3
adaptor-related protein complex 1, sigma 3 subunit
chr5_+_139027868 0.224 CXXC5
CXXC finger protein 5
chr15_+_74218786 0.222 NM_005576
LOXL1
lysyl oxidase-like 1
chr6_+_35995513 0.220 MAPK14
mitogen-activated protein kinase 14
chr9_+_133320093 0.219 NM_000050
NM_054012
ASS1

argininosuccinate synthase 1

chr11_-_22851266 0.218 NM_148893
SVIP
small VCP/p97-interacting protein
chr14_-_99947113 0.218 SETD3
SET domain containing 3
chr21_-_38639593 0.217 DSCR3
Down syndrome critical region gene 3
chrX_-_118827155 0.217 SEPT6
septin 6
chr5_+_126626455 0.213 NM_032446
MEGF10
multiple EGF-like-domains 10
chr7_-_766875 0.213 NM_001164760
PRKAR1B
protein kinase, cAMP-dependent, regulatory, type I, beta
chr16_-_1876792 0.212 HAGH
hydroxyacylglutathione hydrolase
chr15_+_41245635 0.210 NM_001142776
NM_024111
CHAC1

ChaC, cation transport regulator homolog 1 (E. coli)

chr22_+_32870829 0.209 FBXO7
F-box protein 7
chr14_-_99947080 0.206 SETD3
SET domain containing 3
chr11_+_64001974 0.206 NM_001243733
NM_003377
VEGFB

vascular endothelial growth factor B

chr17_-_73266276 0.206 NM_001242500
NM_001242501
MIF4GD

MIF4G domain containing

chr2_-_27294491 0.206 NM_001134693
OST4
oligosaccharyltransferase 4 homolog (S. cerevisiae)
chr16_+_1584161 0.204 NM_024600
TMEM204
transmembrane protein 204
chrX_-_118827116 0.202 SEPT6
septin 6
chr5_+_156693051 0.202 NM_001037333
NM_001037332
CYFIP2

cytoplasmic FMR1 interacting protein 2

chr22_-_29977075 0.202 NM_001202502
NIPSNAP1
nipsnap homolog 1 (C. elegans)
chr22_+_32870997 0.201 FBXO7
F-box protein 7
chr1_-_151804225 0.201 NM_005060
RORC
RAR-related orphan receptor C
chr22_+_32870731 0.200 FBXO7
F-box protein 7
chr16_+_2880172 0.196 NM_145252
ZG16B
zymogen granule protein 16 homolog B (rat)
chr10_+_31608097 0.196 NM_001174093
NM_001174095
NM_001174096
NM_030751
ZEB1



zinc finger E-box binding homeobox 1



chr1_+_120254418 0.195 NM_006623
PHGDH
phosphoglycerate dehydrogenase
chr6_-_35696359 0.194 NM_001145775
FKBP5
FK506 binding protein 5
chr19_-_47734215 0.192 NM_014417
BBC3
BCL2 binding component 3
chr19_+_12863406 0.191 NM_017682
BEST2
bestrophin 2
chr8_+_104383785 0.190 NM_138455
CTHRC1
collagen triple helix repeat containing 1
chrX_-_118827060 0.190 SEPT6
septin 6
chr2_-_193059249 0.185 TMEFF2
transmembrane protein with EGF-like and two follistatin-like domains 2
chr8_+_104383701 0.183 CTHRC1
collagen triple helix repeat containing 1
chr7_+_12726910 0.182 NM_001195396
NM_005738
ARL4A

ADP-ribosylation factor-like 4A

chr2_-_219925237 0.181 NM_002181
IHH
Indian hedgehog
chr15_+_89182038 0.181 NM_002201
ISG20
interferon stimulated exonuclease gene 20kDa
chr4_+_41258941 0.180 UCHL1
ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
chr14_+_105781180 0.180 PACS2
phosphofurin acidic cluster sorting protein 2
chr8_-_141467810 0.178 TRAPPC9
trafficking protein particle complex 9
chr3_-_178789597 0.178 NM_022470
NM_152240
ZMAT3

zinc finger, matrin-type 3

chr16_+_691827 0.177 NM_138418
FAM195A
family with sequence similarity 195, member A
chr17_+_39405938 0.176 NM_033191
KRTAP9-4
keratin associated protein 9-4
chr7_-_122526410 0.176 CADPS2
Ca++-dependent secretion activator 2
chr1_-_33168356 0.176 NM_001161708
NM_030786
SYNC

syncoilin, intermediate filament protein

chr17_-_66596934 0.176 NM_001243746
NM_017565
FAM20A

family with sequence similarity 20, member A

chr6_+_35995453 0.175 NM_001315
NM_139012
NM_139013
NM_139014
MAPK14



mitogen-activated protein kinase 14



chr3_-_178789535 0.175 ZMAT3
zinc finger, matrin-type 3
chr17_+_40440481 0.175 STAT5A
signal transducer and activator of transcription 5A
chr17_+_29298042 0.175 RNF135
ring finger protein 135
chr21_+_45553485 0.173 NM_004649
NM_198155
C21orf33

chromosome 21 open reading frame 33

chr5_+_139027907 0.172 CXXC5
CXXC finger protein 5
chr5_-_132112887 0.171 NM_001098811
NM_001098812
NM_015146
SEPT8


septin 8


chr4_-_41216455 0.169 NM_001166050
NM_004307
NM_173075
APBB2


amyloid beta (A4) precursor protein-binding, family B, member 2


chr2_+_210288668 0.167 NM_001039538
MAP2
microtubule-associated protein 2
chr14_+_105780903 0.167 PACS2
phosphofurin acidic cluster sorting protein 2
chr10_+_94833231 0.167 NM_057157
CYP26A1
cytochrome P450, family 26, subfamily A, polypeptide 1
chr6_-_46459010 0.166 NM_001251974
RCAN2
regulator of calcineurin 2
chrX_-_118827322 0.166 NM_015129
NM_145799
NM_145800
NM_145802
SEPT6



septin 6



chr1_+_89990396 0.165 NM_001134476
LRRC8B
leucine rich repeat containing 8 family, member B
chr17_-_21156577 0.165 NM_152914
C17orf103
chromosome 17 open reading frame 103
chr17_-_79514664 0.164 C17orf70
chromosome 17 open reading frame 70
chr11_+_47279467 0.163 NM_001130101
NM_005693
NR1H3

nuclear receptor subfamily 1, group H, member 3

chr1_+_153631193 0.161 SNAPIN
SNAP-associated protein
chr17_-_66596736 0.160 FAM20A
family with sequence similarity 20, member A
chrX_-_13956445 0.160


chr2_+_14772839 0.159 FAM84A
family with sequence similarity 84, member A
chr4_+_41258895 0.159 NM_004181
UCHL1
ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
chr1_+_65720091 0.158 LOC645195
DNAJC6
uncharacterized LOC645195
DnaJ (Hsp40) homolog, subfamily C, member 6
chr4_+_41258909 0.158 UCHL1
ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
chr6_+_80340971 0.158 NM_031469
SH3BGRL2
SH3 domain binding glutamic acid-rich protein like 2
chr5_+_169532900 0.157 NM_012188
NM_144769
FOXI1

forkhead box I1

chr17_+_39394269 0.156 NM_031963
KRTAP9-8
keratin associated protein 9-8
chr1_-_182354649 0.156 GLUL
glutamate-ammonia ligase
chr5_+_95067511 0.155


chr19_+_13205956 0.155 NFIX
nuclear factor I/X (CCAAT-binding transcription factor)
chr17_-_28619183 0.153 NM_000386
BLMH
bleomycin hydrolase
chr12_+_56075329 0.152 NM_152637
METTL7B
methyltransferase like 7B
chr10_+_92980507 0.151 PCGF5
polycomb group ring finger 5
chr10_-_31607919 0.151 ZEB1-AS1
ZEB1 antisense RNA 1 (non-protein coding)
chr20_+_62688438 0.151 NM_198723
TCEA2
transcription elongation factor A (SII), 2
chr5_+_76248679 0.150 NM_001882
CRHBP
corticotropin releasing hormone binding protein
chr22_-_50893728 0.150 SBF1
SET binding factor 1
chr1_-_182361311 0.150 NM_001033044
NM_002065
GLUL

glutamate-ammonia ligase

chr7_+_130794854 0.150 NM_001145354
MKLN1
muskelin 1, intracellular mediator containing kelch motifs
chr17_-_4890920 0.150 NM_001171166
NM_015099
CAMTA2

calmodulin binding transcription activator 2

chr11_+_12132063 0.149 NM_014632
MICAL2
microtubule associated monoxygenase, calponin and LIM domain containing 2
chr14_+_105190533 0.149 NM_152328
ADSSL1
adenylosuccinate synthase like 1
chr21_-_38639625 0.149 NM_006052
DSCR3
Down syndrome critical region gene 3
chr1_+_6685209 0.149 NM_001195752
NM_138350
THAP3

THAP domain containing, apoptosis associated protein 3

chr10_+_31607419 0.148 ZEB1
zinc finger E-box binding homeobox 1
chr1_-_24741586 0.147 NM_001199012
C1orf201
chromosome 1 open reading frame 201
chr5_-_133747592 0.147 NM_080656
CDKN2AIPNL
CDKN2A interacting protein N-terminal like
chr8_+_72756218 0.146 LOC100132891
uncharacterized LOC100132891
chr1_+_6094342 0.145 NM_001199860
KCNAB2
potassium voltage-gated channel, shaker-related subfamily, beta member 2
chr8_+_72756335 0.144


chr11_-_86383355 0.144 NM_006680
ME3
malic enzyme 3, NADP(+)-dependent, mitochondrial
chr12_+_56367832 0.144 RAB5B
RAB5B, member RAS oncogene family
chr17_-_73267261 0.143 NM_001242498
NM_020679
MIF4GD

MIF4G domain containing

chr8_-_143867931 0.143 NM_003695
LY6D
lymphocyte antigen 6 complex, locus D
chrX_-_15872905 0.142


chr11_+_64879294 0.141 NM_003273
TM7SF2
transmembrane 7 superfamily member 2
chrX_-_153775427 0.141 G6PD
glucose-6-phosphate dehydrogenase
chr3_-_133614296 0.140 RAB6B
RAB6B, member RAS oncogene family
chr11_+_308106 0.140 NM_006435
IFITM2
interferon induced transmembrane protein 2 (1-8D)
chr17_-_76921453 0.139 NM_003255
TIMP2
TIMP metallopeptidase inhibitor 2
chr12_+_7342956 0.139 NM_000319
PEX5
peroxisomal biogenesis factor 5
chr1_+_65991390 0.139 LEPR
leptin receptor
chr5_+_130599745 0.138 CDC42SE2
CDC42 small effector 2
chr17_-_39222126 0.138 NM_033184
KRTAP2-4
keratin associated protein 2-4
chr15_-_48470319 0.137 MYEF2
myelin expression factor 2
chr11_-_86383164 0.137 NM_001014811
ME3
malic enzyme 3, NADP(+)-dependent, mitochondrial
chr1_+_145438437 0.137 NM_006472
TXNIP
thioredoxin interacting protein
chr4_+_3443691 0.136 NM_001528
HGFAC
HGF activator
chr12_+_56075418 0.136 METTL7B
methyltransferase like 7B
chr17_-_39165343 0.136 NM_031958
KRTAP3-1
keratin associated protein 3-1
chr16_+_691901 0.135 FAM195A
family with sequence similarity 195, member A
chr19_+_8478181 0.135 NM_001005415
NM_001005416
NM_016496
MARCH2


membrane-associated ring finger (C3HC4) 2


chr14_+_24605393 0.135 PSME1
proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)
chr17_-_6947241 0.133 NM_153357
SLC16A11
solute carrier family 16, member 11 (monocarboxylic acid transporter 11)
chr4_+_129732427 0.133 PHF17
PHD finger protein 17
chr16_-_1876528 0.132 HAGH
hydroxyacylglutathione hydrolase
chr2_-_31361364 0.132


chr17_-_73267072 0.131 MIF4GD
MIF4G domain containing
chr10_+_94608224 0.131 NM_019053
EXOC6
exocyst complex component 6
chr14_+_105941061 0.131 NM_001312
CRIP2
cysteine-rich protein 2
chr18_-_34408845 0.131 TPGS2
tubulin polyglutamylase complex subunit 2
chr17_-_46035109 0.131 NM_024320
PRR15L
proline rich 15-like
chr3_+_52719935 0.130 NM_014366
NM_206825
NM_206826
GNL3


guanine nucleotide binding protein-like 3 (nucleolar)


chr19_+_56159400 0.130 CCDC106
coiled-coil domain containing 106
chr16_-_1821709 0.130 NM_002513
NME3
non-metastatic cells 3, protein expressed in
chr2_-_224702300 0.129 NM_001039569
AP1S3
adaptor-related protein complex 1, sigma 3 subunit
chr10_+_112257624 0.128 NM_004419
DUSP5
dual specificity phosphatase 5
chr9_-_35689902 0.128 NM_003289
NM_213674
TPM2

tropomyosin 2 (beta)

chr9_-_21559696 0.128 MIR31HG
MIR31 host gene (non-protein coding)
chr2_+_27274490 0.127 NM_001035507
NM_021831
AGBL5

ATP/GTP binding protein-like 5

chr8_+_356807 0.127 NM_012173
NM_183420
NM_183421
FBXO25


F-box protein 25


chr12_-_76953526 0.127 OSBPL8
oxysterol binding protein-like 8
chr9_-_35689799 0.127 TPM2
tropomyosin 2 (beta)
chr15_+_74218811 0.127 LOXL1
lysyl oxidase-like 1
chr1_-_153518265 0.127 NM_002961
NM_019554
S100A4

S100 calcium binding protein A4

chr5_+_139028483 0.127 CXXC5
CXXC finger protein 5
chr1_-_182360889 0.127 GLUL
glutamate-ammonia ligase
chr12_+_122459791 0.126 NM_001024808
NM_020993
BCL7A

B-cell CLL/lymphoma 7A

chr17_+_5972425 0.126 WSCD1
WSC domain containing 1
chr18_-_34408699 0.126 TPGS2
tubulin polyglutamylase complex subunit 2
chrX_+_152908819 0.126 DUSP9
dual specificity phosphatase 9
chr4_+_3443659 0.126 HGFAC
HGF activator
chr12_-_63328663 0.126 NM_020700
PPM1H
protein phosphatase, Mg2+/Mn2+ dependent, 1H

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.15 1.99e-07 GO:0050794 regulation of cellular process
1.13 2.60e-06 GO:0050789 regulation of biological process
1.12 2.70e-05 GO:0065007 biological regulation
1.07 1.39e-04 GO:0009987 cellular process
1.18 3.40e-04 GO:0051716 cellular response to stimulus
1.33 1.17e-03 GO:0035556 intracellular signal transduction
1.24 1.50e-03 GO:0048519 negative regulation of biological process
1.18 1.76e-03 GO:0023052 signaling
1.37 2.30e-03 GO:0032268 regulation of cellular protein metabolic process
1.28 2.97e-03 GO:0023051 regulation of signaling
1.18 3.21e-03 GO:0007165 signal transduction
1.24 3.81e-03 GO:0048523 negative regulation of cellular process
1.68 6.89e-03 GO:0031329 regulation of cellular catabolic process
1.33 1.25e-02 GO:0051246 regulation of protein metabolic process
1.28 1.99e-02 GO:0009966 regulation of signal transduction
1.17 3.81e-02 GO:0048856 anatomical structure development
1.37 4.92e-02 GO:0031399 regulation of protein modification process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.11 1.07e-16 GO:0005622 intracellular
1.12 1.94e-16 GO:0044424 intracellular part
1.16 4.57e-14 GO:0005737 cytoplasm
1.34 2.51e-09 GO:0005829 cytosol
1.09 6.29e-05 GO:0043229 intracellular organelle
1.08 7.26e-05 GO:0043226 organelle
1.13 1.93e-04 GO:0044444 cytoplasmic part
1.12 3.78e-03 GO:0005634 nucleus
1.55 6.51e-03 GO:0048471 perinuclear region of cytoplasm
1.07 3.71e-02 GO:0043231 intracellular membrane-bounded organelle
1.07 4.03e-02 GO:0043227 membrane-bounded organelle

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.16 2.98e-10 GO:0005515 protein binding
1.57 3.00e-05 GO:0008092 cytoskeletal protein binding
1.06 6.45e-04 GO:0005488 binding
1.79 2.00e-02 GO:0000287 magnesium ion binding