Motif ID: MAFB.p2

Z-value: 2.228


Transcription factors associated with MAFB.p2:

Gene SymbolEntrez IDGene Name
MAFB 9935 v-maf musculoaponeurotic fibrosarcoma oncogene homolog B (avian)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
MAFBchr20_-_39317875-0.294.8e-01Click!


Activity profile for motif MAFB.p2.

activity profile for motif MAFB.p2


Sorted Z-values histogram for motif MAFB.p2

Sorted Z-values for motif MAFB.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of MAFB.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr14_-_60337350 5.734 NM_021136
RTN1
reticulon 1
chr5_+_92920592 4.031 NR2F1
NR2F2
nuclear receptor subfamily 2, group F, member 1
nuclear receptor subfamily 2, group F, member 2
chr15_-_48937068 3.898 FBN1
fibrillin 1
chr3_+_110790460 2.657 NM_001243286
NM_015480
PVRL3

poliovirus receptor-related 3

chr6_+_72596699 2.625 RIMS1
regulating synaptic membrane exocytosis 1
chr1_-_57045214 2.614 PPAP2B
phosphatidic acid phosphatase type 2B
chr13_+_102104941 2.362 NM_004791
ITGBL1
integrin, beta-like 1 (with EGF-like repeat domains)
chr4_+_15004297 2.285 NM_001177381
NM_001177382
NM_001177383
NM_001177384
NM_182485
NM_182646
CPEB2





cytoplasmic polyadenylation element binding protein 2





chr8_+_37654757 2.210 GPR124
G protein-coupled receptor 124
chr7_-_137531585 2.191 NM_004717
DGKI
diacylglycerol kinase, iota
chr8_+_37654406 2.158 GPR124
G protein-coupled receptor 124
chr1_-_57044980 2.143 PPAP2B
phosphatidic acid phosphatase type 2B
chr12_+_90102639 2.115 LOC338758
uncharacterized LOC338758
chr1_-_57045235 2.111 NM_003713
PPAP2B
phosphatidic acid phosphatase type 2B
chr10_-_79397394 2.038 KCNMA1
potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr11_-_35547144 2.006 NM_001001991
NM_015430
PAMR1

peptidase domain containing associated with muscle regeneration 1

chr5_+_95067511 1.979


chr10_-_79397204 1.935 KCNMA1
potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr18_-_25756946 1.918 CDH2
cadherin 2, type 1, N-cadherin (neuronal)
chr2_-_225907312 1.885 NM_014689
DOCK10
dedicator of cytokinesis 10
chr8_+_37654395 1.808 NM_032777
GPR124
G protein-coupled receptor 124
chrX_+_153672490 1.795 FAM50A
family with sequence similarity 50, member A
chr6_+_124125068 1.794 NM_001040214
NM_153355
NKAIN2

Na+/K+ transporting ATPase interacting 2

chr2_+_217498205 1.790 IGFBP2
insulin-like growth factor binding protein 2, 36kDa
chr12_+_56075418 1.763 METTL7B
methyltransferase like 7B
chr10_-_79397470 1.717 KCNMA1
potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr7_+_8008416 1.677 NM_138426
GLCCI1
glucocorticoid induced transcript 1
chr14_-_60097531 1.668 NM_206852
RTN1
reticulon 1
chr19_+_2476122 1.640 NM_015675
GADD45B
growth arrest and DNA-damage-inducible, beta
chr16_+_2039945 1.635 NM_004209
SYNGR3
synaptogyrin 3
chr10_+_31610063 1.633 NM_001128128
NM_001174094
ZEB1

zinc finger E-box binding homeobox 1

chr10_+_31608097 1.584 NM_001174093
NM_001174095
NM_001174096
NM_030751
ZEB1



zinc finger E-box binding homeobox 1



chr3_-_187463227 1.568 BCL6
B-cell CLL/lymphoma 6
chr3_-_187463474 1.558 NM_001706
BCL6
B-cell CLL/lymphoma 6
chr2_-_68547018 1.519 NM_001111101
NM_015463
CNRIP1

cannabinoid receptor interacting protein 1

chr8_-_108510094 1.510 NM_001146
NM_001199859
ANGPT1

angiopoietin 1

chr19_+_36359346 1.510 NM_001024807
NM_005166
APLP1

amyloid beta (A4) precursor-like protein 1

chr6_+_72596405 1.498 RIMS1
regulating synaptic membrane exocytosis 1
chr16_-_73092533 1.482 NM_001164766
ZFHX3
zinc finger homeobox 3
chr2_+_109745996 1.429 NM_001099289
SH3RF3
SH3 domain containing ring finger 3
chr5_+_119800004 1.407 NM_016644
PRR16
proline rich 16
chr6_+_72596648 1.386 NM_014989
RIMS1
regulating synaptic membrane exocytosis 1
chr16_+_1584161 1.377 NM_024600
TMEM204
transmembrane protein 204
chr5_-_14871555 1.331 NM_054027
ANKH
ankylosis, progressive homolog (mouse)
chr5_+_119799898 1.327 PRR16
proline rich 16
chr16_+_29823408 1.292 NM_145239
PRRT2
proline-rich transmembrane protein 2
chrX_-_154114431 1.288 NM_019863
F8
coagulation factor VIII, procoagulant component
chr13_-_44361032 1.281 NM_001242863
NM_017993
ENOX1

ecto-NOX disulfide-thiol exchanger 1

chr7_+_7222142 1.269 NM_020156
C1GALT1
core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1
chr1_-_72748491 1.226


chr20_-_34025955 1.224 NM_000557
GDF5
growth differentiation factor 5
chr12_-_40499604 1.224 NM_052885
SLC2A13
solute carrier family 2 (facilitated glucose transporter), member 13
chr2_+_191745546 1.221 NM_014905
GLS
glutaminase
chr1_-_241520467 1.201 NM_002924
RGS7
regulator of G-protein signaling 7
chr6_-_85473898 1.197 NM_001080508
TBX18
T-box 18
chr17_-_28619183 1.167 NM_000386
BLMH
bleomycin hydrolase
chrX_+_153672449 1.161 NM_004699
FAM50A
family with sequence similarity 50, member A
chr5_+_139060295 1.155 CXXC5
CXXC finger protein 5
chr12_-_91576579 1.148 DCN
decorin
chr3_-_45267068 1.141 TMEM158
transmembrane protein 158 (gene/pseudogene)
chr19_+_14551080 1.130 NM_213560
PKN1
protein kinase N1
chr2_+_23608297 1.128 NM_052920
KLHL29
kelch-like 29 (Drosophila)
chr11_+_113930430 1.127 NM_006006
ZBTB16
zinc finger and BTB domain containing 16
chr1_+_183605207 1.111 NM_015149
RGL1
ral guanine nucleotide dissociation stimulator-like 1
chr12_-_91576805 1.102 NM_001920
DCN
decorin
chr14_-_60097314 1.094 RTN1
reticulon 1
chr14_+_100259445 1.092 NM_001008707
NM_004434
EML1

echinoderm microtubule associated protein like 1

chr10_-_79397290 1.089 KCNMA1
potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr10_+_60272868 1.056 NM_001080512
BICC1
bicaudal C homolog 1 (Drosophila)
chr5_+_40680021 1.045 NM_000958
PTGER4
prostaglandin E receptor 4 (subtype EP4)
chr20_-_34330093 1.040 RBM39
RNA binding motif protein 39
chr14_-_60097223 1.037 RTN1
reticulon 1
chr7_+_100199881 1.036 NM_002593
PCOLCE
procollagen C-endopeptidase enhancer
chr4_-_57522469 1.014 NM_001145459
NM_139211
HOPX

HOP homeobox

chr8_-_92053043 1.009 NM_018710
TMEM55A
transmembrane protein 55A
chr4_-_89618928 1.004 NM_153757
NAP1L5
nucleosome assembly protein 1-like 5
chr16_+_69600110 1.001 NFAT5
nuclear factor of activated T-cells 5, tonicity-responsive
chr15_+_63335086 1.000 TPM1
tropomyosin 1 (alpha)
chr1_-_241520384 0.987 RGS7
regulator of G-protein signaling 7
chr8_-_60031545 0.971 NM_014729
TOX
thymocyte selection-associated high mobility group box
chr18_-_25757351 0.967 NM_001792
CDH2
cadherin 2, type 1, N-cadherin (neuronal)
chr11_-_70672644 0.954 SHANK2
SH3 and multiple ankyrin repeat domains 2
chrX_-_118827060 0.948 SEPT6
septin 6
chr10_-_79397546 0.929 NM_001014797
NM_001161352
NM_001161353
NM_002247
KCNMA1



potassium large conductance calcium-activated channel, subfamily M, alpha member 1



chr2_+_189839078 0.924 NM_000090
COL3A1
collagen, type III, alpha 1
chr20_-_48099178 0.922 NM_004975
KCNB1
potassium voltage-gated channel, Shab-related subfamily, member 1
chr5_-_146833150 0.920 NM_001387
DPYSL3
dihydropyrimidinase-like 3
chr2_+_217498082 0.919 NM_000597
IGFBP2
insulin-like growth factor binding protein 2, 36kDa
chr20_+_33146500 0.898 NM_032514
MAP1LC3A
microtubule-associated protein 1 light chain 3 alpha
chr5_-_36151953 0.891 NM_001007527
LMBRD2
LMBR1 domain containing 2
chr5_+_137774897 0.876 REEP2
receptor accessory protein 2
chr2_+_191745791 0.873 GLS
glutaminase
chr5_+_176237435 0.873 NM_133369
UNC5A
unc-5 homolog A (C. elegans)
chr4_+_15005364 0.870 CPEB2
cytoplasmic polyadenylation element binding protein 2
chr1_+_163038564 0.869 NM_005613
RGS4
regulator of G-protein signaling 4
chr1_-_24194760 0.865 NM_000147
FUCA1
fucosidase, alpha-L- 1, tissue
chrX_+_51486479 0.850 NM_018094
GSPT2
G1 to S phase transition 2
chr20_-_35374530 0.846 NM_022477
NM_032013
NDRG3

NDRG family member 3

chr17_-_8702438 0.845 NM_152599
MFSD6L
major facilitator superfamily domain containing 6-like
chr2_+_189839113 0.841 COL3A1
collagen, type III, alpha 1
chr3_-_129325175 0.839 NM_015103
PLXND1
plexin D1
chr1_-_43232728 0.834 NM_001146289
NM_001243246
NM_022356
LEPRE1


leucine proline-enriched proteoglycan (leprecan) 1


chr6_-_139695349 0.832 NM_001168389
NM_001168388
CITED2

Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2

chr13_+_32605436 0.818 NM_023037
FRY
furry homolog (Drosophila)
chr17_-_28618836 0.812 BLMH
bleomycin hydrolase
chr17_+_61851512 0.811


chr5_-_146889618 0.811 NM_001197294
DPYSL3
dihydropyrimidinase-like 3
chr22_-_21905372 0.811 NM_001128635
RIMBP3B
RIMS binding protein 3B
chr1_+_64239566 0.807 NM_001083592
NM_005012
ROR1

receptor tyrosine kinase-like orphan receptor 1

chr16_+_29823557 0.806 PRRT2
proline-rich transmembrane protein 2
chr14_-_23821423 0.802 NM_020372
SLC22A17
solute carrier family 22, member 17
chr2_-_202316227 0.801 NM_015049
TRAK2
trafficking protein, kinesin binding 2
chr3_+_49027770 0.800 P4HTM
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
chr19_-_47922468 0.797 MEIS3
Meis homeobox 3
chr7_-_27183225 0.797 NM_019102
HOXA5
homeobox A5
chr10_-_32635842 0.783 EPC1
enhancer of polycomb homolog 1 (Drosophila)
chr1_-_43232656 0.780 LEPRE1
leucine proline-enriched proteoglycan (leprecan) 1
chr9_-_110251754 0.778 KLF4
Kruppel-like factor 4 (gut)
chr12_-_6665220 0.770 NM_001039670
NM_001193457
NM_080730
IFFO1


intermediate filament family orphan 1


chr15_+_43809805 0.758 NM_002373
MAP1A
microtubule-associated protein 1A
chr2_+_189839132 0.742 COL3A1
collagen, type III, alpha 1
chr8_+_104383785 0.735 NM_138455
CTHRC1
collagen triple helix repeat containing 1
chr10_+_89419352 0.735 NM_001015880
NM_004670
PAPSS2

3'-phosphoadenosine 5'-phosphosulfate synthase 2

chr15_+_63334753 0.732 NM_000366
NM_001018004
NM_001018005
NM_001018006
NM_001018007
NM_001018020
TPM1





tropomyosin 1 (alpha)





chr1_+_51434231 0.731 NM_001262
CDKN2C
cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
chr19_-_18392436 0.716 JUND
jun D proto-oncogene
chr22_-_29075708 0.712 NM_001145418
TTC28
tetratricopeptide repeat domain 28
chr7_+_94024201 0.709 COL1A2
collagen, type I, alpha 2
chr8_+_27183047 0.708 PTK2B
PTK2B protein tyrosine kinase 2 beta
chr2_+_191745568 0.708 GLS
glutaminase
chr5_+_178450775 0.706 NM_001136116
ZNF879
zinc finger protein 879
chr19_-_40791224 0.705 AKT2
v-akt murine thymoma viral oncogene homolog 2
chrX_+_66766350 0.701 AR
androgen receptor
chr11_-_67188614 0.700 PPP1CA
protein phosphatase 1, catalytic subunit, alpha isozyme
chr2_+_24299751 0.699 LOC375190
UPF0638 protein B
chr6_-_111804413 0.699 NM_002912
REV3L
REV3-like, catalytic subunit of DNA polymerase zeta (yeast)
chr5_+_137774632 0.698 NM_016606
REEP2
receptor accessory protein 2
chr5_-_137368682 0.696 FAM13B
family with sequence similarity 13, member B
chr1_+_178063302 0.696 RASAL2
RAS protein activator like 2
chr8_+_104383701 0.693 CTHRC1
collagen triple helix repeat containing 1
chr20_+_34742656 0.692 NM_012156
EPB41L1
erythrocyte membrane protein band 4.1-like 1
chr16_+_2802634 0.692 SRRM2
serine/arginine repetitive matrix 2
chr3_+_32280211 0.689 CMTM8
CKLF-like MARVEL transmembrane domain containing 8
chr5_-_159546389 0.684 NM_001130864
NM_052927
PWWP2A

PWWP domain containing 2A

chr4_+_174292100 0.684 SAP30
Sin3A-associated protein, 30kDa
chr5_+_139060058 0.683 CXXC5
CXXC finger protein 5
chr1_-_182360400 0.680 NM_001033056
GLUL
glutamate-ammonia ligase
chr19_-_31840118 0.679 NM_020856
TSHZ3
teashirt zinc finger homeobox 3
chr1_-_57045129 0.675 PPAP2B
phosphatidic acid phosphatase type 2B
chr13_+_49549953 0.675 NM_001079673
FNDC3A
fibronectin type III domain containing 3A
chr3_+_20081853 0.670 KAT2B
K(lysine) acetyltransferase 2B
chr11_+_113931228 0.669 NM_001018011
ZBTB16
zinc finger and BTB domain containing 16
chr12_-_29936685 0.669 NM_001193451
TMTC1
transmembrane and tetratricopeptide repeat containing 1
chr2_-_227663454 0.668 NM_005544
IRS1
insulin receptor substrate 1
chr2_-_45236521 0.667 NM_016932
SIX2
SIX homeobox 2
chr4_-_138453564 0.662 PCDH18
protocadherin 18
chr3_+_32280154 0.661 NM_178868
CMTM8
CKLF-like MARVEL transmembrane domain containing 8
chr4_-_138453628 0.655 NM_019035
PCDH18
protocadherin 18
chr15_+_96873845 0.654 NM_021005
NR2F2
nuclear receptor subfamily 2, group F, member 2
chr4_-_18023358 0.654 NM_001166139
NM_153686
LCORL

ligand dependent nuclear receptor corepressor-like

chr17_-_48264039 0.653 COL1A1
collagen, type I, alpha 1
chr8_+_27183062 0.651 NM_173175
PTK2B
PTK2B protein tyrosine kinase 2 beta
chr6_-_111804106 0.650 REV3L
REV3-like, catalytic subunit of DNA polymerase zeta (yeast)
chr14_+_53019865 0.648 NM_001099652
GPR137C
G protein-coupled receptor 137C
chr2_+_202316391 0.648 NM_001206864
NM_018571
STRADB

STE20-related kinase adaptor beta

chr12_-_63328663 0.647 NM_020700
PPM1H
protein phosphatase, Mg2+/Mn2+ dependent, 1H
chr21_-_34100210 0.646 SYNJ1
synaptojanin 1
chr4_+_174292027 0.646 NM_003864
SAP30
Sin3A-associated protein, 30kDa
chr20_+_35089817 0.642 NM_001042486
DLGAP4
discs, large (Drosophila) homolog-associated protein 4
chr5_+_139060186 0.641 CXXC5
CXXC finger protein 5
chr6_-_132272311 0.635 NM_001901
CTGF
connective tissue growth factor
chr15_-_55880508 0.632 PYGO1
pygopus homolog 1 (Drosophila)
chr3_+_105085740 0.628 ALCAM
activated leukocyte cell adhesion molecule
chr1_+_178063237 0.627 RASAL2
RAS protein activator like 2
chr5_+_140602914 0.626 NM_018934
PCDHB14
protocadherin beta 14
chr5_+_75699003 0.625 NM_006633
IQGAP2
IQ motif containing GTPase activating protein 2
chr17_+_39240412 0.625 NM_033061
KRTAP4-7
keratin associated protein 4-7
chr15_-_78369825 0.622 NM_015079
NM_144572
TBC1D2B

TBC1 domain family, member 2B

chr14_+_50087400 0.618 NM_002408
MGAT2
mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
chr1_-_31845818 0.617 NM_004102
FABP3
fatty acid binding protein 3, muscle and heart (mammary-derived growth inhibitor)
chr4_+_153457407 0.616 DKFZP434I0714
uncharacterized protein DKFZP434I0714
chr4_-_2263706 0.612 NM_006454
MXD4
MAX dimerization protein 4
chr2_+_74741565 0.610 NM_016170
TLX2
T-cell leukemia homeobox 2
chr14_+_38678594 0.610 SSTR1
somatostatin receptor 1
chrX_-_154688260 0.609 NM_001007523
NM_001007524
NM_012151
F8A2
F8A3
F8A1
coagulation factor VIII-associated 2
coagulation factor VIII-associated 3
coagulation factor VIII-associated 1
chr4_+_126237566 0.607 NM_024582
FAT4
FAT tumor suppressor homolog 4 (Drosophila)
chr8_+_27182995 0.604 NM_173176
PTK2B
PTK2B protein tyrosine kinase 2 beta
chrX_-_118827322 0.604 NM_015129
NM_145799
NM_145800
NM_145802
SEPT6



septin 6



chr5_-_137368778 0.603 NM_001101800
NM_001101801
NM_016603
FAM13B


family with sequence similarity 13, member B


chr1_-_92351613 0.602 NM_001195683
NM_003243
TGFBR3

transforming growth factor, beta receptor III

chr8_-_57123827 0.598 PLAG1
pleiomorphic adenoma gene 1
chrX_+_16964730 0.597 NM_001080975
NM_004726
REPS2

RALBP1 associated Eps domain containing 2

chr5_-_137089434 0.591 HNRNPA0
heterogeneous nuclear ribonucleoprotein A0
chr14_+_29236882 0.590 FOXG1
forkhead box G1
chr9_-_120177326 0.590 ASTN2
astrotactin 2
chr13_+_98086315 0.589 NM_021033
RAP2A
RAP2A, member of RAS oncogene family
chr2_-_198175494 0.589 NM_001195144
NM_153697
ANKRD44

ankyrin repeat domain 44

chr1_-_92351476 0.588 TGFBR3
transforming growth factor, beta receptor III
chr14_-_61115906 0.588 NM_005982
SIX1
SIX homeobox 1
chr15_-_90294359 0.587 NM_018670
MESP1
mesoderm posterior 1 homolog (mouse)

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.10 2.30e-14 GO:0009987 cellular process
1.31 1.20e-10 GO:0048523 negative regulation of cellular process
1.28 1.35e-09 GO:0048519 negative regulation of biological process
1.48 2.82e-09 GO:0022008 neurogenesis
1.36 4.89e-09 GO:0007399 nervous system development
1.49 5.43e-09 GO:0048699 generation of neurons
1.43 3.59e-07 GO:0048468 cell development
1.58 5.50e-07 GO:0000904 cell morphogenesis involved in differentiation
1.35 1.16e-06 GO:0051641 cellular localization
1.12 1.22e-06 GO:0050794 regulation of cellular process
1.28 1.43e-06 GO:0006464 protein modification process
1.53 1.56e-06 GO:0048666 neuron development
1.57 1.57e-06 GO:0031175 neuron projection development
1.17 1.62e-06 GO:0044260 cellular macromolecule metabolic process
1.23 2.51e-06 GO:0044267 cellular protein metabolic process
1.19 4.00e-06 GO:0016043 cellular component organization
1.46 5.12e-06 GO:0030182 neuron differentiation
1.25 5.18e-06 GO:0048869 cellular developmental process
1.26 5.74e-06 GO:0030154 cell differentiation
1.60 6.12e-06 GO:0007409 axonogenesis
1.11 6.31e-06 GO:0050789 regulation of biological process
1.39 7.77e-06 GO:0010605 negative regulation of macromolecule metabolic process
1.26 9.84e-06 GO:0043412 macromolecule modification
1.57 1.20e-05 GO:0048667 cell morphogenesis involved in neuron differentiation
1.12 1.25e-05 GO:0044237 cellular metabolic process
1.56 2.28e-05 GO:0048812 neuron projection morphogenesis
1.38 2.72e-05 GO:0031324 negative regulation of cellular metabolic process
1.18 3.52e-05 GO:0071840 cellular component organization or biogenesis
1.18 3.69e-05 GO:0080090 regulation of primary metabolic process
1.36 3.75e-05 GO:0009892 negative regulation of metabolic process
1.45 4.21e-05 GO:0030030 cell projection organization
1.17 4.49e-05 GO:0032502 developmental process
1.10 4.64e-05 GO:0065007 biological regulation
1.46 7.00e-05 GO:0000902 cell morphogenesis
1.17 7.19e-05 GO:0031323 regulation of cellular metabolic process
1.50 7.79e-05 GO:0048858 cell projection morphogenesis
1.17 1.01e-04 GO:0007275 multicellular organismal development
1.19 1.09e-04 GO:0048731 system development
1.44 1.13e-04 GO:0032989 cellular component morphogenesis
1.39 1.47e-04 GO:0046907 intracellular transport
1.49 1.49e-04 GO:0032990 cell part morphogenesis
1.18 1.65e-04 GO:0048856 anatomical structure development
1.38 2.00e-04 GO:0051128 regulation of cellular component organization
1.27 2.30e-04 GO:0009653 anatomical structure morphogenesis
1.32 2.60e-04 GO:0051649 establishment of localization in cell
1.20 2.70e-04 GO:0071842 cellular component organization at cellular level
1.35 3.10e-04 GO:0050793 regulation of developmental process
1.17 3.14e-04 GO:0060255 regulation of macromolecule metabolic process
1.49 4.74e-04 GO:0072358 cardiovascular system development
1.49 4.74e-04 GO:0072359 circulatory system development
1.32 5.26e-04 GO:0008104 protein localization
1.58 5.60e-04 GO:0007411 axon guidance
1.13 7.75e-04 GO:0043170 macromolecule metabolic process
1.15 9.39e-04 GO:0023052 signaling
1.44 1.06e-03 GO:0051253 negative regulation of RNA metabolic process
1.36 1.36e-03 GO:0031399 regulation of protein modification process
1.39 1.42e-03 GO:0045595 regulation of cell differentiation
1.24 1.50e-03 GO:0023051 regulation of signaling
1.34 1.65e-03 GO:0045184 establishment of protein localization
1.36 2.38e-03 GO:2000026 regulation of multicellular organismal development
1.36 2.43e-03 GO:0016192 vesicle-mediated transport
1.18 2.87e-03 GO:0071841 cellular component organization or biogenesis at cellular level
1.19 3.12e-03 GO:0048522 positive regulation of cellular process
1.14 5.15e-03 GO:0019222 regulation of metabolic process
1.39 5.81e-03 GO:0010629 negative regulation of gene expression
1.41 5.83e-03 GO:0045892 negative regulation of transcription, DNA-dependent
1.29 5.90e-03 GO:0032268 regulation of cellular protein metabolic process
1.16 6.06e-03 GO:0019538 protein metabolic process
1.39 6.16e-03 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.32 6.67e-03 GO:0015031 protein transport
1.28 7.76e-03 GO:0051246 regulation of protein metabolic process
1.54 9.24e-03 GO:0032870 cellular response to hormone stimulus
1.37 9.63e-03 GO:0007167 enzyme linked receptor protein signaling pathway
1.09 9.67e-03 GO:0008152 metabolic process
1.25 1.13e-02 GO:0051239 regulation of multicellular organismal process
1.41 1.24e-02 GO:0070727 cellular macromolecule localization
1.31 1.27e-02 GO:0006351 transcription, DNA-dependent
1.80 1.32e-02 GO:0008286 insulin receptor signaling pathway
1.24 1.32e-02 GO:0035556 intracellular signal transduction
1.35 1.33e-02 GO:0009890 negative regulation of biosynthetic process
1.41 1.37e-02 GO:0034613 cellular protein localization
1.37 1.45e-02 GO:0051172 negative regulation of nitrogen compound metabolic process
1.37 1.48e-02 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
1.35 1.73e-02 GO:0031327 negative regulation of cellular biosynthetic process
1.09 1.88e-02 GO:0044238 primary metabolic process
1.35 2.12e-02 GO:0010558 negative regulation of macromolecule biosynthetic process
1.16 2.13e-02 GO:0051171 regulation of nitrogen compound metabolic process
1.26 2.14e-02 GO:0010604 positive regulation of macromolecule metabolic process
1.28 2.30e-02 GO:0006793 phosphorus metabolic process
1.28 2.30e-02 GO:0006796 phosphate metabolic process
1.34 2.56e-02 GO:0009719 response to endogenous stimulus
1.28 2.65e-02 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.39 2.79e-02 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
1.34 2.79e-02 GO:0019220 regulation of phosphate metabolic process
1.34 2.79e-02 GO:0051174 regulation of phosphorus metabolic process
1.49 2.80e-02 GO:0071495 cellular response to endogenous stimulus
1.14 2.92e-02 GO:0051179 localization
1.24 2.95e-02 GO:0033036 macromolecule localization
1.23 3.29e-02 GO:0009966 regulation of signal transduction
1.70 3.72e-02 GO:0031400 negative regulation of protein modification process
1.35 3.78e-02 GO:0009725 response to hormone stimulus
1.25 3.83e-02 GO:0044248 cellular catabolic process
1.16 4.82e-02 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.11 2.18e-22 GO:0005622 intracellular
1.11 5.38e-21 GO:0044424 intracellular part
1.12 4.81e-15 GO:0043229 intracellular organelle
1.11 5.75e-15 GO:0043226 organelle
1.17 2.54e-11 GO:0005634 nucleus
1.12 2.97e-11 GO:0005737 cytoplasm
1.11 6.27e-11 GO:0043227 membrane-bounded organelle
1.11 8.20e-11 GO:0043231 intracellular membrane-bounded organelle
1.24 1.04e-09 GO:0043234 protein complex
1.20 3.56e-08 GO:0032991 macromolecular complex
1.23 1.42e-05 GO:0005829 cytosol
1.12 4.36e-05 GO:0044422 organelle part
1.19 5.28e-05 GO:0043228 non-membrane-bounded organelle
1.19 5.28e-05 GO:0043232 intracellular non-membrane-bounded organelle
1.12 7.57e-05 GO:0044446 intracellular organelle part
1.25 1.90e-04 GO:0005856 cytoskeleton
1.50 1.92e-04 GO:0043005 neuron projection
1.10 3.62e-04 GO:0044444 cytoplasmic part
1.20 3.83e-04 GO:0044428 nuclear part
1.31 9.24e-04 GO:0042995 cell projection
1.21 1.09e-03 GO:0031981 nuclear lumen
1.43 1.59e-03 GO:0005768 endosome
1.33 2.97e-03 GO:0044451 nucleoplasm part
1.26 3.66e-03 GO:0044430 cytoskeletal part
1.23 5.81e-03 GO:0005654 nucleoplasm
1.36 6.66e-03 GO:0005694 chromosome
1.91 7.71e-03 GO:0016585 chromatin remodeling complex
2.09 9.35e-03 GO:0030426 growth cone
1.62 1.18e-02 GO:0031252 cell leading edge
2.03 1.96e-02 GO:0030427 site of polarized growth
1.46 2.20e-02 GO:0015629 actin cytoskeleton
1.43 2.61e-02 GO:0005815 microtubule organizing center
1.53 2.91e-02 GO:0016604 nuclear body
1.80 3.12e-02 GO:0019717 synaptosome
1.71 4.20e-02 GO:0016607 nuclear speck
1.38 4.45e-02 GO:0045202 synapse

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.21 6.37e-29 GO:0005515 protein binding
1.11 3.95e-23 GO:0005488 binding
1.40 1.48e-05 GO:0019899 enzyme binding
1.34 2.38e-05 GO:0030528 transcription regulator activity
1.45 7.35e-05 GO:0008092 cytoskeletal protein binding
1.20 9.81e-05 GO:0000166 nucleotide binding
1.54 1.09e-03 GO:0016564 transcription repressor activity
1.44 1.85e-03 GO:0019904 protein domain specific binding
2.86 3.09e-03 GO:0005158 insulin receptor binding
1.55 3.87e-03 GO:0032403 protein complex binding
1.34 5.35e-03 GO:0043565 sequence-specific DNA binding
1.27 1.18e-02 GO:0001071 nucleic acid binding transcription factor activity
1.27 1.18e-02 GO:0003700 sequence-specific DNA binding transcription factor activity
1.12 2.34e-02 GO:0043167 ion binding
1.12 2.48e-02 GO:0046872 metal ion binding
1.11 3.34e-02 GO:0043169 cation binding