Motif ID: MAFB.p2

Z-value: 2.228


Transcription factors associated with MAFB.p2:

Gene SymbolEntrez IDGene Name
MAFB 9935 v-maf musculoaponeurotic fibrosarcoma oncogene homolog B (avian)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
MAFBchr20_-_39317875-0.294.8e-01Click!


Activity profile for motif MAFB.p2.

activity profile for motif MAFB.p2


Sorted Z-values histogram for motif MAFB.p2

Sorted Z-values for motif MAFB.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of MAFB.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr14_-_60337350 5.734 NM_021136
 RTN1
reticulon 1
chr5_+_92920592 4.031 NR2F1
NR2F2
nuclear receptor subfamily 2, group F, member 1
nuclear receptor subfamily 2, group F, member 2
chr15_-_48937068 3.898 FBN1
fibrillin 1
chr3_+_110790460 2.657 NM_001243286
NM_015480
 PVRL3

poliovirus receptor-related 3

chr6_+_72596699 2.625 RIMS1
regulating synaptic membrane exocytosis 1
chr1_-_57045214 2.614 PPAP2B
phosphatidic acid phosphatase type 2B
chr13_+_102104941 2.362 NM_004791
 ITGBL1
integrin, beta-like 1 (with EGF-like repeat domains)
chr4_+_15004297 2.285 NM_001177381
NM_001177382
NM_001177383
NM_001177384
NM_182485
NM_182646
 CPEB2





cytoplasmic polyadenylation element binding protein 2





chr8_+_37654757 2.210 GPR124
G protein-coupled receptor 124
chr7_-_137531585 2.191 NM_004717
 DGKI
diacylglycerol kinase, iota
chr8_+_37654406 2.158 GPR124
G protein-coupled receptor 124
chr1_-_57044980 2.143 PPAP2B
phosphatidic acid phosphatase type 2B
chr12_+_90102639 2.115 LOC338758
uncharacterized LOC338758
chr1_-_57045235 2.111 NM_003713
 PPAP2B
phosphatidic acid phosphatase type 2B
chr10_-_79397394 2.038 KCNMA1
potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr11_-_35547144 2.006 NM_001001991
NM_015430
 PAMR1

peptidase domain containing associated with muscle regeneration 1

chr5_+_95067511 1.979


chr10_-_79397204 1.935 KCNMA1
potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr18_-_25756946 1.918 CDH2
cadherin 2, type 1, N-cadherin (neuronal)
chr2_-_225907312 1.885 NM_014689
 DOCK10
dedicator of cytokinesis 10

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 103 entries
enrichment   p-value GO term description
1.80 1.32e-02 GO:0008286 insulin receptor signaling pathway
1.70 3.72e-02 GO:0031400 negative regulation of protein modification process
1.60 6.12e-06 GO:0007409 axonogenesis
1.58 5.50e-07 GO:0000904 cell morphogenesis involved in differentiation
1.58 5.60e-04 GO:0007411 axon guidance
1.57 1.57e-06 GO:0031175 neuron projection development
1.57 1.20e-05 GO:0048667 cell morphogenesis involved in neuron differentiation
1.56 2.28e-05 GO:0048812 neuron projection morphogenesis
1.54 9.24e-03 GO:0032870 cellular response to hormone stimulus
1.53 1.56e-06 GO:0048666 neuron development
1.50 7.79e-05 GO:0048858 cell projection morphogenesis
1.49 5.43e-09 GO:0048699 generation of neurons
1.49 1.49e-04 GO:0032990 cell part morphogenesis
1.49 4.74e-04 GO:0072358 cardiovascular system development
1.49 4.74e-04 GO:0072359 circulatory system development
1.49 2.80e-02 GO:0071495 cellular response to endogenous stimulus
1.48 2.82e-09 GO:0022008 neurogenesis
1.46 5.12e-06 GO:0030182 neuron differentiation
1.46 7.00e-05 GO:0000902 cell morphogenesis
1.45 4.21e-05 GO:0030030 cell projection organization

Gene overrepresentation in compartment category:

Showing 1 to 20 of 36 entries
enrichment   p-value GO term description
2.09 9.35e-03 GO:0030426 growth cone
2.03 1.96e-02 GO:0030427 site of polarized growth
1.91 7.71e-03 GO:0016585 chromatin remodeling complex
1.80 3.12e-02 GO:0019717 synaptosome
1.71 4.20e-02 GO:0016607 nuclear speck
1.62 1.18e-02 GO:0031252 cell leading edge
1.53 2.91e-02 GO:0016604 nuclear body
1.50 1.92e-04 GO:0043005 neuron projection
1.46 2.20e-02 GO:0015629 actin cytoskeleton
1.43 1.59e-03 GO:0005768 endosome
1.43 2.61e-02 GO:0005815 microtubule organizing center
1.38 4.45e-02 GO:0045202 synapse
1.36 6.66e-03 GO:0005694 chromosome
1.33 2.97e-03 GO:0044451 nucleoplasm part
1.31 9.24e-04 GO:0042995 cell projection
1.26 3.66e-03 GO:0044430 cytoskeletal part
1.25 1.90e-04 GO:0005856 cytoskeleton
1.24 1.04e-09 GO:0043234 protein complex
1.23 1.42e-05 GO:0005829 cytosol
1.23 5.81e-03 GO:0005654 nucleoplasm

Gene overrepresentation in function category:

Showing 1 to 16 of 16 entries
enrichment   p-value GO term description
2.86 3.09e-03 GO:0005158 insulin receptor binding
1.55 3.87e-03 GO:0032403 protein complex binding
1.54 1.09e-03 GO:0016564 transcription repressor activity
1.45 7.35e-05 GO:0008092 cytoskeletal protein binding
1.44 1.85e-03 GO:0019904 protein domain specific binding
1.40 1.48e-05 GO:0019899 enzyme binding
1.34 2.38e-05 GO:0030528 transcription regulator activity
1.34 5.35e-03 GO:0043565 sequence-specific DNA binding
1.27 1.18e-02 GO:0001071 nucleic acid binding transcription factor activity
1.27 1.18e-02 GO:0003700 sequence-specific DNA binding transcription factor activity
1.21 6.37e-29 GO:0005515 protein binding
1.20 9.81e-05 GO:0000166 nucleotide binding
1.12 2.34e-02 GO:0043167 ion binding
1.12 2.48e-02 GO:0046872 metal ion binding
1.11 3.95e-23 GO:0005488 binding
1.11 3.34e-02 GO:0043169 cation binding