Motif ID: MAZ.p2

Z-value: 1.471


Transcription factors associated with MAZ.p2:

Gene SymbolEntrez IDGene Name
MAZ 4150 MYC-associated zinc finger protein (purine-binding transcription factor)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
MAZchr16_+_29817810-0.294.9e-01Click!


Activity profile for motif MAZ.p2.

activity profile for motif MAZ.p2


Sorted Z-values histogram for motif MAZ.p2

Sorted Z-values for motif MAZ.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of MAZ.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr19_-_291168 3.814 NM_177543
 PPAP2C
phosphatidic acid phosphatase type 2C
chr19_-_291335 3.789 NM_003712
NM_177526
 PPAP2C

phosphatidic acid phosphatase type 2C

chr8_+_95653272 3.062 ESRP1
epithelial splicing regulatory protein 1
chr8_+_95653399 2.574 ESRP1
epithelial splicing regulatory protein 1
chr8_+_95653340 2.141 NM_001034915
NM_001122825
NM_001122826
NM_001122827
NM_017697
 ESRP1




epithelial splicing regulatory protein 1




chr3_-_10547221 1.726 ATP2B2
ATPase, Ca++ transporting, plasma membrane 2
chr6_+_37137882 1.717 NM_001243186
NM_002648
 PIM1

pim-1 oncogene

chr7_+_69064316 1.613 AUTS2
autism susceptibility candidate 2
chr1_-_11714738 1.599 NM_012168
 FBXO2
F-box protein 2
chr18_+_33877630 1.522 NM_025135
 FHOD3
formin homology 2 domain containing 3
chr7_-_98030165 1.456 BAIAP2L1
BAI1-associated protein 2-like 1
chr1_+_955609 1.424 AGRN
agrin
chr1_+_955468 1.403 NM_198576
 AGRN
agrin
chr1_-_160068359 1.380 NM_052868
 IGSF8
immunoglobulin superfamily, member 8
chr17_-_47841517 1.303 NM_030802
 FAM117A
family with sequence similarity 117, member A
chr1_-_175161832 1.287 NM_001162895
NM_014656
NM_001162893
NM_001162894
 KIAA0040



KIAA0040



chr1_+_60280462 1.269 NM_015888
 HOOK1
hook homolog 1 (Drosophila)
chr19_-_15090349 1.251 SLC1A6
solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6
chr3_-_13921617 1.233 NM_004625
 WNT7A
wingless-type MMTV integration site family, member 7A
chr8_+_86376130 1.211 NM_000067
 CA2
carbonic anhydrase II

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 110 entries
enrichment   p-value GO term description
1.72 1.52e-02 GO:0031124 mRNA 3'-end processing
1.42 6.57e-03 GO:0001701 in utero embryonic development
1.41 4.05e-03 GO:0048011 nerve growth factor receptor signaling pathway
1.41 4.58e-02 GO:0016569 covalent chromatin modification
1.40 6.45e-09 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
1.40 6.98e-06 GO:0009792 embryo development ending in birth or egg hatching
1.40 7.28e-06 GO:0043009 chordate embryonic development
1.39 1.03e-08 GO:0045892 negative regulation of transcription, DNA-dependent
1.39 1.53e-07 GO:0048646 anatomical structure formation involved in morphogenesis
1.37 6.17e-08 GO:0051253 negative regulation of RNA metabolic process
1.36 5.02e-09 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
1.36 1.66e-08 GO:0010629 negative regulation of gene expression
1.36 2.71e-08 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.36 7.04e-05 GO:0000122 negative regulation of transcription from RNA polymerase II promoter
1.35 6.31e-09 GO:0010558 negative regulation of macromolecule biosynthetic process
1.35 3.29e-08 GO:0051172 negative regulation of nitrogen compound metabolic process
1.34 1.04e-08 GO:0031327 negative regulation of cellular biosynthetic process
1.34 2.00e-08 GO:0009890 negative regulation of biosynthetic process
1.33 1.63e-07 GO:0007167 enzyme linked receptor protein signaling pathway
1.32 3.70e-02 GO:0060284 regulation of cell development

Gene overrepresentation in compartment category:

Showing 1 to 20 of 26 entries
enrichment   p-value GO term description
1.42 6.85e-03 GO:0070161 anchoring junction
1.30 3.83e-03 GO:0048471 perinuclear region of cytoplasm
1.24 1.57e-03 GO:0030054 cell junction
1.20 1.13e-06 GO:0005654 nucleoplasm
1.20 1.37e-02 GO:0044451 nucleoplasm part
1.18 2.22e-08 GO:0005829 cytosol
1.17 5.32e-08 GO:0070013 intracellular organelle lumen
1.17 6.30e-07 GO:0031981 nuclear lumen
1.16 7.85e-08 GO:0043233 organelle lumen
1.16 1.13e-07 GO:0031974 membrane-enclosed lumen
1.15 4.17e-06 GO:0044428 nuclear part
1.15 2.38e-02 GO:0005783 endoplasmic reticulum
1.14 1.47e-20 GO:0005634 nucleus
1.11 2.60e-22 GO:0005737 cytoplasm
1.10 1.98e-23 GO:0043227 membrane-bounded organelle
1.10 2.21e-23 GO:0043231 intracellular membrane-bounded organelle
1.10 4.24e-10 GO:0044444 cytoplasmic part
1.09 2.61e-35 GO:0005622 intracellular
1.09 1.08e-33 GO:0044424 intracellular part
1.09 2.66e-20 GO:0043229 intracellular organelle

Gene overrepresentation in function category:

Showing 1 to 20 of 33 entries
enrichment   p-value GO term description
1.54 3.17e-02 GO:0005088 Ras guanyl-nucleotide exchange factor activity
1.49 4.95e-03 GO:0004713 protein tyrosine kinase activity
1.33 3.25e-03 GO:0016564 transcription repressor activity
1.32 3.07e-02 GO:0005261 cation channel activity
1.31 3.30e-04 GO:0004674 protein serine/threonine kinase activity
1.30 1.11e-07 GO:0016773 phosphotransferase activity, alcohol group as acceptor
1.30 4.47e-07 GO:0043565 sequence-specific DNA binding
1.30 3.86e-06 GO:0004672 protein kinase activity
1.28 7.15e-10 GO:0001071 nucleic acid binding transcription factor activity
1.28 7.15e-10 GO:0003700 sequence-specific DNA binding transcription factor activity
1.28 3.92e-07 GO:0016301 kinase activity
1.28 3.67e-03 GO:0019904 protein domain specific binding
1.25 7.09e-05 GO:0019899 enzyme binding
1.25 1.48e-02 GO:0060589 nucleoside-triphosphatase regulator activity
1.24 1.27e-06 GO:0030528 transcription regulator activity
1.24 4.32e-02 GO:0030695 GTPase regulator activity
1.23 5.04e-05 GO:0016772 transferase activity, transferring phosphorus-containing groups
1.20 3.64e-02 GO:0046983 protein dimerization activity
1.17 1.14e-04 GO:0032559 adenyl ribonucleotide binding
1.16 1.77e-04 GO:0030554 adenyl nucleotide binding