Motif ID: MYFfamily.p2

Z-value: 1.936


Transcription factors associated with MYFfamily.p2:

Gene SymbolEntrez IDGene Name
MYF5 4617 myogenic factor 5
MYF6 4618 myogenic factor 6 (herculin)
MYOD1 4654 myogenic differentiation 1
MYOG 4656 myogenin (myogenic factor 4)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
MYF5chr12_+_81110689-0.373.7e-01Click!
MYF6chr12_+_811014070.373.7e-01Click!
MYOGchr1_-_203055088,
chr1_-_203055376
-0.294.9e-01Click!
MYOD1chr11_+_177411090.137.5e-01Click!


Activity profile for motif MYFfamily.p2.

activity profile for motif MYFfamily.p2


Sorted Z-values histogram for motif MYFfamily.p2

Sorted Z-values for motif MYFfamily.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of MYFfamily.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_-_231114596 2.088 TTC13
tetratricopeptide repeat domain 13
chr1_-_231114617 1.988 NM_001122835
NM_024525
TTC13

tetratricopeptide repeat domain 13

chr14_-_105634708 1.723 JAG2
jagged 2
chr12_-_71003622 1.708 NM_001206971
NM_001206972
NM_002837
PTPRB


protein tyrosine phosphatase, receptor type, B


chr13_-_36050758 1.677 NM_005584
MAB21L1
mab-21-like 1 (C. elegans)
chr17_-_39306053 1.598 NM_033188
KRTAP4-5
keratin associated protein 4-5
chr17_-_39324423 1.522 NM_033187
KRTAP4-3
keratin associated protein 4-3
chr1_-_231114580 1.518 TTC13
tetratricopeptide repeat domain 13
chr1_+_109792640 1.506 NM_001408
CELSR2
cadherin, EGF LAG seven-pass G-type receptor 2 (flamingo homolog, Drosophila)
chr8_-_23712297 1.464 NM_003155
STC1
stanniocalcin 1
chr20_-_23066828 1.446 NM_012072
CD93
CD93 molecule
chr13_-_72440143 1.430 DACH1
dachshund homolog 1 (Drosophila)
chr1_-_58716207 1.329 NM_021080
DAB1
disabled homolog 1 (Drosophila)
chr1_-_53793743 1.327 NM_001018054
NM_004631
NM_017522
NM_033300
LRP8



low density lipoprotein receptor-related protein 8, apolipoprotein e receptor



chr14_-_105635114 1.263 NM_002226
NM_145159
JAG2

jagged 2

chr19_-_44174271 1.243 PLAUR
plasminogen activator, urokinase receptor
chr20_+_13202417 1.202 NM_080826
ISM1
isthmin 1 homolog (zebrafish)
chr12_-_112036257 1.198 ATXN2
ataxin 2
chr3_-_10547221 1.146 ATP2B2
ATPase, Ca++ transporting, plasma membrane 2
chr11_-_1629614 1.143 NM_001012708
KRTAP5-3
keratin associated protein 5-3
chr9_+_114393543 1.130 NM_001015882
NM_004125
DNAJC25
DNAJC25-GNG10
DnaJ (Hsp40) homolog, subfamily C , member 25
DNAJC25-GNG10 readthrough
chr2_-_47797469 1.061 NM_022055
KCNK12
potassium channel, subfamily K, member 12
chr19_-_43969723 1.047 NM_014400
LYPD3
LY6/PLAUR domain containing 3
chr15_-_74726258 1.006 NM_001146029
NM_003612
SEMA7A

semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group)

chr5_+_140346053 0.960 PCDHAC2
protocadherin alpha subfamily C, 2
chr6_+_99282597 0.958 POU3F2
POU class 3 homeobox 2
chr15_-_74726000 0.923 NM_001146030
SEMA7A
semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group)
chr15_+_90744506 0.903 NM_198925
SEMA4B
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B
chr3_+_140770412 0.897 SPSB4
splA/ryanodine receptor domain and SOCS box containing 4
chr1_+_233749749 0.895 NM_002245
KCNK1
potassium channel, subfamily K, member 1
chr4_+_154387450 0.865 NM_001131007
NM_015196
KIAA0922

KIAA0922

chr4_-_6202251 0.860 NM_001099433
NM_144720
JAKMIP1

janus kinase and microtubule interacting protein 1

chr20_+_3451727 0.858 ATRN
attractin
chr19_-_44174497 0.852 NM_001005376
NM_001005377
NM_002659
PLAUR


plasminogen activator, urokinase receptor


chr2_+_206547352 0.842 NRP2
neuropilin 2
chr1_+_231114794 0.838 NM_022786
ARV1
ARV1 homolog (S. cerevisiae)
chr17_-_39538635 0.834 NM_021013
KRT34
keratin 34
chr3_-_167813058 0.828 GOLIM4
golgi integral membrane protein 4
chr5_+_52284903 0.827 NM_002203
ITGA2
integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
chr6_+_7727010 0.807 NM_001718
BMP6
bone morphogenetic protein 6
chr4_-_84256012 0.794 NM_001098540
HPSE
heparanase
chr2_-_230579198 0.793 NM_139072
DNER
delta/notch-like EGF repeat containing
chr3_-_169381417 0.792 NM_001205194
NM_004991
MECOM

MDS1 and EVI1 complex locus

chr16_-_74640997 0.769 GLG1
golgi glycoprotein 1
chrX_-_30327479 0.767 NM_000475
NR0B1
nuclear receptor subfamily 0, group B, member 1
chr22_+_29279573 0.766 NM_001206998
ZNRF3
zinc and ring finger 3
chr1_-_6662681 0.756 KLHL21
kelch-like 21 (Drosophila)
chr11_+_92702788 0.743 NM_005959
MTNR1B
melatonin receptor 1B
chr2_-_39187477 0.741 LOC375196
uncharacterized LOC375196
chr16_-_74640915 0.732 GLG1
golgi glycoprotein 1
chr8_-_22550708 0.729 NM_004430
EGR3
early growth response 3
chr10_-_133109983 0.728 NM_174937
TCERG1L
transcription elongation regulator 1-like
chr5_-_139422805 0.717 NM_001184935
NM_004883
NM_013981
NM_013982
NM_013983
NRG2




neuregulin 2




chr1_+_233749917 0.705 KCNK1
potassium channel, subfamily K, member 1
chr13_-_26625164 0.704 NM_001007538
SHISA2
shisa homolog 2 (Xenopus laevis)
chr3_+_110790460 0.703 NM_001243286
NM_015480
PVRL3

poliovirus receptor-related 3

chr1_-_12677347 0.700 NM_004753
DHRS3
dehydrogenase/reductase (SDR family) member 3
chr4_-_74964996 0.700 NM_002089
CXCL2
chemokine (C-X-C motif) ligand 2
chr1_-_177133818 0.699 ASTN1
astrotactin 1
chr1_+_151483861 0.692 NM_020770
CGN
cingulin
chr22_+_21738039 0.690 NM_001128635
RIMBP3B
RIMS binding protein 3B
chr1_-_54519050 0.679 NM_004872
TMEM59
transmembrane protein 59
chr6_-_108395939 0.678 NM_014028
OSTM1
osteopetrosis associated transmembrane protein 1
chr1_+_90286595 0.669 LRRC8D
leucine rich repeat containing 8 family, member D
chr6_-_111804106 0.668 REV3L
REV3-like, catalytic subunit of DNA polymerase zeta (yeast)
chr5_+_140346289 0.663 NM_031883
PCDHAC2
protocadherin alpha subfamily C, 2
chr12_-_85306579 0.657 NM_001146335
NM_018057
NM_182767
SLC6A15


solute carrier family 6 (neutral amino acid transporter), member 15


chr12_-_85306569 0.654 SLC6A15
solute carrier family 6 (neutral amino acid transporter), member 15
chr4_-_103265818 0.653 SLC39A8
solute carrier family 39 (zinc transporter), member 8
chr19_+_54371170 0.649 MYADM
myeloid-associated differentiation marker
chr6_+_31638727 0.645 NM_021221
LY6G5B
lymphocyte antigen 6 complex, locus G5B
chr18_-_22931970 0.644 ZNF521
zinc finger protein 521
chr1_-_6662898 0.631 NM_014851
KLHL21
kelch-like 21 (Drosophila)
chr12_-_76424474 0.629 PHLDA1
pleckstrin homology-like domain, family A, member 1
chr5_-_16617085 0.628 NM_001034850
FAM134B
family with sequence similarity 134, member B
chr11_+_71249070 0.624 NM_021046
KRTAP5-8
keratin associated protein 5-8
chr3_-_4508955 0.613 NM_001164674
NM_001164675
NM_182760
SUMF1


sulfatase modifying factor 1


chr1_-_177133950 0.607 NM_004319
NM_207108
ASTN1

astrotactin 1

chr3_+_126707380 0.605 NM_032242
PLXNA1
plexin A1
chr6_+_45390284 0.605 RUNX2
runt-related transcription factor 2
chr12_+_101188373 0.601 NM_178826
ANO4
anoctamin 4
chr4_-_84255999 0.601 HPSE
heparanase
chr9_-_128003634 0.598 NM_005347
HSPA5
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
chr1_-_59042827 0.596 TACSTD2
tumor-associated calcium signal transducer 2
chr17_-_39216343 0.593 NM_001165252
LOC730755
keratin associated protein 2-4-like
chr12_+_53491417 0.586 NM_002178
IGFBP6
insulin-like growth factor binding protein 6
chr18_+_21269528 0.584 NM_001127717
NM_198129
LAMA3

laminin, alpha 3

chr6_-_143832770 0.579 NM_032020
FUCA2
fucosidase, alpha-L- 2, plasma
chr16_+_5121809 0.577 NM_019109
ALG1
asparagine-linked glycosylation 1, beta-1,4-mannosyltransferase homolog (S. cerevisiae)
chr3_+_9773395 0.577 BRPF1
bromodomain and PHD finger containing, 1
chr1_-_53793583 0.571 LRP8
low density lipoprotein receptor-related protein 8, apolipoprotein e receptor
chr5_-_178772328 0.569 ADAMTS2
ADAM metallopeptidase with thrombospondin type 1 motif, 2
chr4_-_129208964 0.568 PGRMC2
progesterone receptor membrane component 2
chr6_+_45390376 0.567 RUNX2
runt-related transcription factor 2
chr9_-_117568292 0.564 NM_005118
TNFSF15
tumor necrosis factor (ligand) superfamily, member 15
chr12_+_53491448 0.561 IGFBP6
insulin-like growth factor binding protein 6
chr21_-_28217272 0.558 ADAMTS1
ADAM metallopeptidase with thrombospondin type 1 motif, 1
chr3_-_196756572 0.557 MFI2
antigen p97 (melanoma associated) identified by monoclonal antibodies 133.2 and 96.5
chr22_-_21905372 0.557 NM_001128635
RIMBP3B
RIMS binding protein 3B
chrY_-_21154560 0.557 NM_013230
CD24
CD24P4
CD24 molecule
CD24 molecule pseudogene 4
chr17_-_39507055 0.553 NM_004138
KRT33A
keratin 33A
chr17_+_7533452 0.551 NM_001040
NM_001146279
NM_001146280
NM_001146281
SHBG



sex hormone-binding globulin



chr3_-_49941300 0.549 NM_001244937
NM_002447
MST1R

macrophage stimulating 1 receptor (c-met-related tyrosine kinase)

chr7_+_20370324 0.546 ITGB8
integrin, beta 8
chr5_+_140254930 0.545 NM_018903
NM_031864
PCDHA12

protocadherin alpha 12

chrX_-_46618596 0.544 SLC9A7
solute carrier family 9 (sodium/hydrogen exchanger), member 7
chr2_+_105471745 0.544 NM_006236
POU3F3
POU class 3 homeobox 3
chr6_+_73331992 0.543 KCNQ5
potassium voltage-gated channel, KQT-like subfamily, member 5
chr5_+_52776263 0.543 NM_006350
NM_013409
FST

follistatin

chr7_+_97736118 0.540 NM_014916
LMTK2
lemur tyrosine kinase 2
chr3_+_9773439 0.539 BRPF1
bromodomain and PHD finger containing, 1
chr7_-_100860615 0.537 PLOD3
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3
chr1_+_224804175 0.537 NM_152495
CNIH3
cornichon homolog 3 (Drosophila)
chr9_-_128003348 0.536 HSPA5
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
chr4_+_75310852 0.535 NM_001657
AREG
amphiregulin
chr3_-_4508939 0.529 SUMF1
sulfatase modifying factor 1
chr6_+_1611544 0.528 FOXC1
forkhead box C1
chr3_-_189838907 0.528 NM_018192
LEPREL1
leprecan-like 1
chr2_-_11810254 0.526 NM_012344
NTSR2
neurotensin receptor 2
chr1_+_183155361 0.525 LAMC2
laminin, gamma 2
chr2_+_220408352 0.524 TMEM198
transmembrane protein 198
chr4_-_129208928 0.524 PGRMC2
progesterone receptor membrane component 2
chr3_-_190040192 0.523 NM_021101
CLDN1
claudin 1
chr12_-_112037024 0.522 ATXN2
ataxin 2
chr22_+_33197678 0.520 TIMP3
TIMP metallopeptidase inhibitor 3
chr16_-_17564737 0.520 NM_022166
XYLT1
xylosyltransferase I
chr4_+_74735107 0.520 NM_001511
CXCL1
chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
chr10_-_73848263 0.519 SPOCK2
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
chr3_+_9773427 0.519 NM_001003694
NM_004634
BRPF1

bromodomain and PHD finger containing, 1

chr21_+_46117086 0.518 NM_198699
KRTAP10-12
keratin associated protein 10-12
chr7_-_124405029 0.517 GPR37
G protein-coupled receptor 37 (endothelin receptor type B-like)
chr14_-_52535737 0.516 NID2
nidogen 2 (osteonidogen)
chr1_+_218519576 0.516 TGFB2
transforming growth factor, beta 2
chr12_-_14720553 0.516 PLBD1
phospholipase B domain containing 1
chr12_+_124196941 0.514 ATP6V0A2
ATPase, H+ transporting, lysosomal V0 subunit a2
chr20_+_3451615 0.512 NM_001207047
NM_139321
NM_139322
ATRN


attractin


chr16_-_88923233 0.511 GALNS
galactosamine (N-acetyl)-6-sulfate sulfatase
chr10_-_103578172 0.511 MGEA5
meningioma expressed antigen 5 (hyaluronidase)
chr17_-_7165788 0.511 CLDN7
claudin 7
chr20_+_44520203 0.510 CTSA
cathepsin A
chr11_-_102668822 0.510 MMP1
matrix metallopeptidase 1 (interstitial collagenase)
chr3_-_196756682 0.506 NM_033316
NM_005929
MFI2

antigen p97 (melanoma associated) identified by monoclonal antibodies 133.2 and 96.5

chr4_-_57976516 0.504 IGFBP7
insulin-like growth factor binding protein 7
chr3_-_4508928 0.504 SUMF1
sulfatase modifying factor 1
chr11_-_102668892 0.504 NM_001145938
NM_002421
MMP1

matrix metallopeptidase 1 (interstitial collagenase)

chr6_-_41122025 0.503 NM_178174
TREML1
triggering receptor expressed on myeloid cells-like 1
chr7_+_55086922 0.503 EGFR
epidermal growth factor receptor
chr20_+_44520021 0.502 CTSA
cathepsin A
chr5_-_178772430 0.501 NM_014244
NM_021599
ADAMTS2

ADAM metallopeptidase with thrombospondin type 1 motif, 2

chr2_-_61765345 0.501 XPO1
exportin 1 (CRM1 homolog, yeast)
chr1_+_179051218 0.500 TOR3A
torsin family 3, member A
chr3_-_79068542 0.495 NM_001145845
NM_133631
ROBO1

roundabout, axon guidance receptor, homolog 1 (Drosophila)

chr12_+_107974633 0.491 NM_001017523
BTBD11
BTB (POZ) domain containing 11
chr10_-_90967048 0.490 NM_003956
CH25H
cholesterol 25-hydroxylase
chr1_+_209848659 0.489 NM_015714
G0S2
G0/G1switch 2
chr1_+_231114839 0.487


chr11_-_2156721 0.486 IGF2
insulin-like growth factor 2 (somatomedin A)
chr10_-_15413054 0.486 NM_001010924
FAM171A1
family with sequence similarity 171, member A1
chr4_+_15704572 0.485 NM_004334
BST1
bone marrow stromal cell antigen 1
chr16_+_57653649 0.483 GPR56
G protein-coupled receptor 56
chr2_+_173292344 0.482 ITGA6
integrin, alpha 6
chr17_+_635656 0.479 NM_024792
FAM57A
family with sequence similarity 57, member A
chr11_-_9113092 0.478 NM_001170690
NM_020974
SCUBE2

signal peptide, CUB domain, EGF-like 2

chr7_+_116660263 0.477 ST7
suppression of tumorigenicity 7
chr16_+_2802708 0.476 SRRM2
serine/arginine repetitive matrix 2
chr1_+_53925071 0.472 NM_033067
DMRTB1
DMRT-like family B with proline-rich C-terminal, 1
chr5_+_99871023 0.471 NM_198507
FAM174A
family with sequence similarity 174, member A
chr12_-_106641675 0.470 NM_006825
CKAP4
cytoskeleton-associated protein 4
chr12_-_54813002 0.467 ITGA5
integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
chr2_+_97426571 0.467 NM_020184
CNNM4
cyclin M4
chr12_+_83080621 0.466 TMTC2
transmembrane and tetratricopeptide repeat containing 2
chr17_-_27621076 0.465 NUFIP2
nuclear fragile X mental retardation protein interacting protein 2
chr22_+_22712091 0.465 IGLV1-44
IGL@
immunoglobulin lambda variable 1-44
immunoglobulin lambda locus
chr16_-_2246464 0.463 NM_020764
CASKIN1
CASK interacting protein 1
chr20_+_2673193 0.463 NM_001110514
EBF4
early B-cell factor 4
chr7_-_100860841 0.462 PLOD3
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3
chr3_+_9773494 0.462 BRPF1
bromodomain and PHD finger containing, 1
chr10_+_64133915 0.461 NM_014951
NM_199450
NM_199451
ZNF365


zinc finger protein 365


chr2_+_206547131 0.459 NM_003872
NM_018534
NM_201264
NM_201266
NM_201267
NM_201279
NRP2





neuropilin 2





chr4_-_57976550 0.459 NM_001253835
NM_001553
IGFBP7

insulin-like growth factor binding protein 7

chr20_+_44519924 0.459 CTSA
cathepsin A
chr2_-_48132656 0.458 NM_001190274
FBXO11
F-box protein 11
chr17_+_20108298 0.458 SPECC1
sperm antigen with calponin homology and coiled-coil domains 1
chr18_-_25756946 0.456 CDH2
cadherin 2, type 1, N-cadherin (neuronal)
chr2_+_62423260 0.452 NM_006577
B3GNT2
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
chr9_+_132816197 0.452 GPR107
G protein-coupled receptor 107
chr14_-_60632019 0.447 DHRS7
dehydrogenase/reductase (SDR family) member 7
chrX_+_128872924 0.444 NM_003399
XPNPEP2
X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound
chrX_-_38079980 0.444 NM_001170750
NM_001170751
NM_001170752
NM_006307
SRPX



sushi-repeat containing protein, X-linked



chr4_-_84256304 0.443 NM_001166498
NM_006665
HPSE

heparanase

chr14_+_102430897 0.442 DYNC1H1
dynein, cytoplasmic 1, heavy chain 1
chr7_+_99955625 0.442 NM_178238
PILRB
paired immunoglobin-like type 2 receptor beta
chr2_+_115199898 0.441 NM_020868
DPP10
dipeptidyl-peptidase 10 (non-functional)
chr1_+_90286469 0.438 NM_001134479
LRRC8D
leucine rich repeat containing 8 family, member D
chr2_+_185463235 0.435 ZNF804A
zinc finger protein 804A
chr7_+_90893735 0.434 NM_003505
FZD1
frizzled family receptor 1
chr14_-_61747956 0.432 TMEM30B
transmembrane protein 30B
chr6_-_31088195 0.432 NM_001264
CDSN
corneodesmosin
chr5_-_147162056 0.432 JAKMIP2
janus kinase and microtubule interacting protein 2
chr1_+_23037329 0.430 NM_004442
NM_017449
EPHB2

EPH receptor B2


Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.28 7.22e-12 GO:0007275 multicellular organismal development
1.26 2.15e-11 GO:0032502 developmental process
1.64 2.47e-10 GO:0007155 cell adhesion
1.64 2.47e-10 GO:0022610 biological adhesion
1.25 5.96e-10 GO:0023052 signaling
1.27 1.69e-09 GO:0048856 anatomical structure development
1.29 2.50e-09 GO:0048731 system development
1.36 2.03e-08 GO:0007166 cell surface receptor linked signaling pathway
1.39 6.01e-08 GO:0007399 nervous system development
1.30 6.70e-07 GO:0065008 regulation of biological quality
1.58 9.14e-07 GO:0007167 enzyme linked receptor protein signaling pathway
1.23 1.00e-06 GO:0007165 signal transduction
1.17 2.38e-06 GO:0032501 multicellular organismal process
1.80 1.64e-05 GO:0016337 cell-cell adhesion
1.42 1.91e-05 GO:0007154 cell communication
1.33 5.40e-05 GO:0009653 anatomical structure morphogenesis
1.28 7.67e-05 GO:0048513 organ development
2.15 7.83e-05 GO:0007156 homophilic cell adhesion
1.56 2.62e-04 GO:0007417 central nervous system development
1.55 3.84e-04 GO:0001775 cell activation
2.03 4.61e-04 GO:0034330 cell junction organization
1.72 5.64e-04 GO:0051270 regulation of cellular component movement
1.24 6.23e-04 GO:0042221 response to chemical stimulus
1.54 8.86e-04 GO:0019226 transmission of nerve impulse
1.54 8.86e-04 GO:0035637 multicellular organismal signaling
1.39 1.84e-03 GO:0048699 generation of neurons
1.69 2.04e-03 GO:0040012 regulation of locomotion
1.60 2.87e-03 GO:0007420 brain development
1.51 3.00e-03 GO:0000904 cell morphogenesis involved in differentiation
1.81 3.04e-03 GO:0009101 glycoprotein biosynthetic process
1.41 3.09e-03 GO:0007267 cell-cell signaling
1.24 3.78e-03 GO:0030154 cell differentiation
1.06 4.16e-03 GO:0009987 cellular process
1.71 4.51e-03 GO:0009100 glycoprotein metabolic process
1.36 5.38e-03 GO:0048468 cell development
1.49 5.56e-03 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
2.52 7.16e-03 GO:0090101 negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway
1.69 7.38e-03 GO:0030334 regulation of cell migration
1.34 8.60e-03 GO:0032879 regulation of localization
1.41 9.96e-03 GO:0030182 neuron differentiation
1.35 1.01e-02 GO:0022008 neurogenesis
1.95 1.14e-02 GO:0034329 cell junction assembly
1.67 1.22e-02 GO:2000145 regulation of cell motility
1.70 1.26e-02 GO:0030168 platelet activation
1.22 1.29e-02 GO:0048869 cellular developmental process
1.36 1.37e-02 GO:0009888 tissue development
2.05 1.38e-02 GO:0007178 transmembrane receptor protein serine/threonine kinase signaling pathway
1.28 1.73e-02 GO:0051239 regulation of multicellular organismal process
1.97 2.59e-02 GO:0090092 regulation of transmembrane receptor protein serine/threonine kinase signaling pathway
2.58 2.62e-02 GO:0030510 regulation of BMP signaling pathway
1.49 2.64e-02 GO:0007268 synaptic transmission
1.31 3.17e-02 GO:0010646 regulation of cell communication
3.04 3.40e-02 GO:0030514 negative regulation of BMP signaling pathway
1.48 3.56e-02 GO:0048812 neuron projection morphogenesis
1.41 3.70e-02 GO:0000902 cell morphogenesis
1.77 4.42e-02 GO:0030900 forebrain development
1.78 4.48e-02 GO:0006486 protein glycosylation
1.78 4.48e-02 GO:0043413 macromolecule glycosylation
2.63 4.98e-02 GO:0030509 BMP signaling pathway

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.25 9.01e-25 GO:0044425 membrane part
1.28 2.20e-24 GO:0031224 intrinsic to membrane
1.27 1.22e-22 GO:0016021 integral to membrane
1.19 2.91e-18 GO:0016020 membrane
1.61 5.32e-16 GO:0005783 endoplasmic reticulum
1.37 5.21e-12 GO:0005576 extracellular region
1.62 2.98e-11 GO:0044432 endoplasmic reticulum part
1.34 3.52e-11 GO:0044459 plasma membrane part
1.43 3.18e-09 GO:0031226 intrinsic to plasma membrane
1.41 4.19e-08 GO:0005887 integral to plasma membrane
1.45 6.81e-08 GO:0044421 extracellular region part
1.35 1.14e-07 GO:0012505 endomembrane system
1.54 3.64e-07 GO:0005789 endoplasmic reticulum membrane
1.53 4.56e-07 GO:0042175 nuclear membrane-endoplasmic reticulum network
1.18 8.97e-07 GO:0071944 cell periphery
1.47 9.48e-07 GO:0005626 insoluble fraction
1.47 1.24e-06 GO:0005624 membrane fraction
1.18 1.65e-06 GO:0005886 plasma membrane
1.36 2.70e-05 GO:0000267 cell fraction
1.43 3.60e-05 GO:0005615 extracellular space
1.62 6.67e-05 GO:0009986 cell surface
1.60 1.34e-04 GO:0031012 extracellular matrix
1.60 1.08e-03 GO:0005578 proteinaceous extracellular matrix
1.31 6.08e-03 GO:0005794 Golgi apparatus
2.01 8.02e-03 GO:0005788 endoplasmic reticulum lumen
1.39 9.32e-03 GO:0044431 Golgi apparatus part
2.21 9.33e-03 GO:0005604 basement membrane

Gene overrepresentation in function category:

enrichment   p-value GO term description
2.37 2.61e-06 GO:0019838 growth factor binding
1.49 1.73e-05 GO:0005509 calcium ion binding
1.34 1.18e-03 GO:0005102 receptor binding
2.25 1.99e-03 GO:0019199 transmembrane receptor protein kinase activity
1.80 4.35e-03 GO:0016758 transferase activity, transferring hexosyl groups
1.80 8.20e-03 GO:0008083 growth factor activity
1.34 1.97e-02 GO:0015075 ion transmembrane transporter activity
1.31 2.52e-02 GO:0022891 substrate-specific transmembrane transporter activity
1.81 2.89e-02 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
3.12 4.70e-02 GO:0005520 insulin-like growth factor binding