Motif ID: MYFfamily.p2

Z-value: 1.936


Transcription factors associated with MYFfamily.p2:

Gene SymbolEntrez IDGene Name
MYF5 4617 myogenic factor 5
MYF6 4618 myogenic factor 6 (herculin)
MYOD1 4654 myogenic differentiation 1
MYOG 4656 myogenin (myogenic factor 4)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
MYF5chr12_+_81110689-0.373.7e-01Click!
MYF6chr12_+_811014070.373.7e-01Click!
MYOGchr1_-_203055088,
chr1_-_203055376		-0.294.9e-01Click!
MYOD1chr11_+_177411090.137.5e-01Click!


Activity profile for motif MYFfamily.p2.

activity profile for motif MYFfamily.p2


Sorted Z-values histogram for motif MYFfamily.p2

Sorted Z-values for motif MYFfamily.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of MYFfamily.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr1_-_231114596 2.088 TTC13
tetratricopeptide repeat domain 13
chr1_-_231114617 1.988 NM_001122835
NM_024525
 TTC13

tetratricopeptide repeat domain 13

chr14_-_105634708 1.723 JAG2
jagged 2
chr12_-_71003622 1.708 NM_001206971
NM_001206972
NM_002837
 PTPRB


protein tyrosine phosphatase, receptor type, B


chr13_-_36050758 1.677 NM_005584
 MAB21L1
mab-21-like 1 (C. elegans)
chr17_-_39306053 1.598 NM_033188
 KRTAP4-5
keratin associated protein 4-5
chr17_-_39324423 1.522 NM_033187
 KRTAP4-3
keratin associated protein 4-3
chr1_-_231114580 1.518 TTC13
tetratricopeptide repeat domain 13
chr1_+_109792640 1.506 NM_001408
 CELSR2
cadherin, EGF LAG seven-pass G-type receptor 2 (flamingo homolog, Drosophila)
chr8_-_23712297 1.464 NM_003155
 STC1
stanniocalcin 1
chr20_-_23066828 1.446 NM_012072
 CD93
CD93 molecule
chr13_-_72440143 1.430 DACH1
dachshund homolog 1 (Drosophila)
chr1_-_58716207 1.329 NM_021080
 DAB1
disabled homolog 1 (Drosophila)
chr1_-_53793743 1.327 NM_001018054
NM_004631
NM_017522
NM_033300
 LRP8



low density lipoprotein receptor-related protein 8, apolipoprotein e receptor



chr14_-_105635114 1.263 NM_002226
NM_145159
 JAG2

jagged 2

chr19_-_44174271 1.243 PLAUR
plasminogen activator, urokinase receptor
chr20_+_13202417 1.202 NM_080826
 ISM1
isthmin 1 homolog (zebrafish)
chr12_-_112036257 1.198 ATXN2
ataxin 2
chr3_-_10547221 1.146 ATP2B2
ATPase, Ca++ transporting, plasma membrane 2
chr11_-_1629614 1.143 NM_001012708
 KRTAP5-3
keratin associated protein 5-3

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 59 entries
enrichment   p-value GO term description
3.04 3.40e-02 GO:0030514 negative regulation of BMP signaling pathway
2.63 4.98e-02 GO:0030509 BMP signaling pathway
2.58 2.62e-02 GO:0030510 regulation of BMP signaling pathway
2.52 7.16e-03 GO:0090101 negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway
2.15 7.83e-05 GO:0007156 homophilic cell adhesion
2.05 1.38e-02 GO:0007178 transmembrane receptor protein serine/threonine kinase signaling pathway
2.03 4.61e-04 GO:0034330 cell junction organization
1.97 2.59e-02 GO:0090092 regulation of transmembrane receptor protein serine/threonine kinase signaling pathway
1.95 1.14e-02 GO:0034329 cell junction assembly
1.81 3.04e-03 GO:0009101 glycoprotein biosynthetic process
1.80 1.64e-05 GO:0016337 cell-cell adhesion
1.78 4.48e-02 GO:0006486 protein glycosylation
1.78 4.48e-02 GO:0043413 macromolecule glycosylation
1.77 4.42e-02 GO:0030900 forebrain development
1.72 5.64e-04 GO:0051270 regulation of cellular component movement
1.71 4.51e-03 GO:0009100 glycoprotein metabolic process
1.70 1.26e-02 GO:0030168 platelet activation
1.69 2.04e-03 GO:0040012 regulation of locomotion
1.69 7.38e-03 GO:0030334 regulation of cell migration
1.67 1.22e-02 GO:2000145 regulation of cell motility

Gene overrepresentation in compartment category:

Showing 1 to 20 of 27 entries
enrichment   p-value GO term description
2.21 9.33e-03 GO:0005604 basement membrane
2.01 8.02e-03 GO:0005788 endoplasmic reticulum lumen
1.62 2.98e-11 GO:0044432 endoplasmic reticulum part
1.62 6.67e-05 GO:0009986 cell surface
1.61 5.32e-16 GO:0005783 endoplasmic reticulum
1.60 1.34e-04 GO:0031012 extracellular matrix
1.60 1.08e-03 GO:0005578 proteinaceous extracellular matrix
1.54 3.64e-07 GO:0005789 endoplasmic reticulum membrane
1.53 4.56e-07 GO:0042175 nuclear membrane-endoplasmic reticulum network
1.47 9.48e-07 GO:0005626 insoluble fraction
1.47 1.24e-06 GO:0005624 membrane fraction
1.45 6.81e-08 GO:0044421 extracellular region part
1.43 3.18e-09 GO:0031226 intrinsic to plasma membrane
1.43 3.60e-05 GO:0005615 extracellular space
1.41 4.19e-08 GO:0005887 integral to plasma membrane
1.39 9.32e-03 GO:0044431 Golgi apparatus part
1.37 5.21e-12 GO:0005576 extracellular region
1.36 2.70e-05 GO:0000267 cell fraction
1.35 1.14e-07 GO:0012505 endomembrane system
1.34 3.52e-11 GO:0044459 plasma membrane part

Gene overrepresentation in function category:

Showing 1 to 10 of 10 entries
enrichment   p-value GO term description
3.12 4.70e-02 GO:0005520 insulin-like growth factor binding
2.37 2.61e-06 GO:0019838 growth factor binding
2.25 1.99e-03 GO:0019199 transmembrane receptor protein kinase activity
1.81 2.89e-02 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
1.80 4.35e-03 GO:0016758 transferase activity, transferring hexosyl groups
1.80 8.20e-03 GO:0008083 growth factor activity
1.49 1.73e-05 GO:0005509 calcium ion binding
1.34 1.18e-03 GO:0005102 receptor binding
1.34 1.97e-02 GO:0015075 ion transmembrane transporter activity
1.31 2.52e-02 GO:0022891 substrate-specific transmembrane transporter activity