Motif ID: MZF1.p2

Z-value: 1.911


Transcription factors associated with MZF1.p2:

Gene SymbolEntrez IDGene Name
MZF1 7593 myeloid zinc finger 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
MZF1chr19_-_59084735,
chr19_-_59084630		0.753.2e-02Click!


Activity profile for motif MZF1.p2.

activity profile for motif MZF1.p2


Sorted Z-values histogram for motif MZF1.p2

Sorted Z-values for motif MZF1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of MZF1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr1_-_57045129 3.141 PPAP2B
phosphatidic acid phosphatase type 2B
chr1_-_57045235 2.800 NM_003713
 PPAP2B
phosphatidic acid phosphatase type 2B
chr21_+_47401644 2.785 NM_001848
 COL6A1
collagen, type VI, alpha 1
chr4_+_145567147 2.604 NM_022475
 HHIP
hedgehog interacting protein
chrX_+_152760346 2.540 NM_001711
 BGN
biglycan
chr1_-_72748147 2.510 NM_173808
 NEGR1
neuronal growth regulator 1
chr1_-_72748491 2.418


chr1_-_57045214 2.310 PPAP2B
phosphatidic acid phosphatase type 2B
chr5_+_92920592 2.238 NR2F1
NR2F2
nuclear receptor subfamily 2, group F, member 1
nuclear receptor subfamily 2, group F, member 2
chr5_+_92918924 2.201 NM_005654
 NR2F1
nuclear receptor subfamily 2, group F, member 1
chr5_+_82767492 2.143 NM_001126336
NM_001164097
NM_001164098
NM_004385
 VCAN



versican



chr7_-_150973819 1.956 NM_001003802
 SMARCD3
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
chr1_-_57044980 1.913 PPAP2B
phosphatidic acid phosphatase type 2B
chr10_+_31608097 1.863 NM_001174093
NM_001174095
NM_001174096
NM_030751
 ZEB1



zinc finger E-box binding homeobox 1



chr8_+_22457098 1.821 NM_001013842
NM_001198827
NM_173686
 C8orf58


chromosome 8 open reading frame 58


chr10_-_79397394 1.717 KCNMA1
potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chrX_+_152760452 1.645 BGN
biglycan
chr1_+_164528586 1.598 NM_001204961
NM_001204963
NM_002585
 PBX1


pre-B-cell leukemia homeobox 1


chr10_-_79397290 1.579 KCNMA1
potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr10_-_79397204 1.553 KCNMA1
potassium large conductance calcium-activated channel, subfamily M, alpha member 1

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 187 entries
enrichment   p-value GO term description
2.24 4.77e-02 GO:0060688 regulation of morphogenesis of a branching structure
1.79 2.87e-02 GO:0010563 negative regulation of phosphorus metabolic process
1.79 2.87e-02 GO:0045936 negative regulation of phosphate metabolic process
1.75 1.85e-02 GO:0030100 regulation of endocytosis
1.70 1.47e-02 GO:0003007 heart morphogenesis
1.63 3.30e-02 GO:0072001 renal system development
1.60 2.43e-02 GO:0010959 regulation of metal ion transport
1.56 2.43e-02 GO:0001655 urogenital system development
1.54 1.65e-04 GO:0051129 negative regulation of cellular component organization
1.54 3.39e-02 GO:0034330 cell junction organization
1.53 2.36e-11 GO:0000904 cell morphogenesis involved in differentiation
1.51 1.76e-05 GO:0051130 positive regulation of cellular component organization
1.51 1.08e-04 GO:0001568 blood vessel development
1.50 2.51e-08 GO:0048667 cell morphogenesis involved in neuron differentiation
1.50 8.29e-03 GO:0044087 regulation of cellular component biogenesis
1.49 1.19e-07 GO:0007409 axonogenesis
1.49 2.43e-03 GO:0006897 endocytosis
1.49 2.43e-03 GO:0010324 membrane invagination
1.49 4.78e-03 GO:0048514 blood vessel morphogenesis
1.48 4.73e-08 GO:0048812 neuron projection morphogenesis

Gene overrepresentation in compartment category:

Showing 1 to 20 of 66 entries
enrichment   p-value GO term description
2.16 1.75e-02 GO:0005720 nuclear heterochromatin
2.10 5.09e-04 GO:0000792 heterochromatin
1.92 1.79e-02 GO:0030672 synaptic vesicle membrane
1.87 2.53e-06 GO:0005925 focal adhesion
1.84 3.93e-06 GO:0005924 cell-substrate adherens junction
1.82 3.42e-06 GO:0030055 cell-substrate junction
1.78 3.98e-04 GO:0008021 synaptic vesicle
1.78 8.51e-04 GO:0000790 nuclear chromatin
1.73 4.76e-02 GO:0030426 growth cone
1.72 4.30e-02 GO:0030427 site of polarized growth
1.68 7.18e-06 GO:0005912 adherens junction
1.65 2.51e-02 GO:0030665 clathrin coated vesicle membrane
1.63 1.90e-05 GO:0070161 anchoring junction
1.63 2.38e-05 GO:0030136 clathrin-coated vesicle
1.62 1.29e-06 GO:0030135 coated vesicle
1.61 4.54e-03 GO:0030662 coated vesicle membrane
1.60 5.24e-05 GO:0044454 nuclear chromosome part
1.56 2.70e-02 GO:0044420 extracellular matrix part
1.55 5.48e-06 GO:0016323 basolateral plasma membrane
1.53 5.44e-05 GO:0000228 nuclear chromosome

Gene overrepresentation in function category:

Showing 1 to 20 of 20 entries
enrichment   p-value GO term description
1.69 1.66e-05 GO:0003714 transcription corepressor activity
1.57 8.84e-05 GO:0003682 chromatin binding
1.45 1.15e-02 GO:0000975 regulatory region DNA binding
1.45 1.15e-02 GO:0001067 regulatory region nucleic acid binding
1.45 1.15e-02 GO:0044212 transcription regulatory region DNA binding
1.45 1.86e-02 GO:0010843 promoter binding
1.44 2.69e-04 GO:0008134 transcription factor binding
1.42 2.31e-06 GO:0019904 protein domain specific binding
1.42 3.03e-03 GO:0032403 protein complex binding
1.40 1.01e-09 GO:0043565 sequence-specific DNA binding
1.39 2.28e-04 GO:0000988 protein binding transcription factor activity
1.39 2.28e-04 GO:0000989 transcription factor binding transcription factor activity
1.39 3.21e-04 GO:0003712 transcription cofactor activity
1.32 5.41e-04 GO:0008092 cytoskeletal protein binding
1.31 5.79e-06 GO:0019899 enzyme binding
1.28 9.96e-07 GO:0030528 transcription regulator activity
1.28 1.72e-06 GO:0001071 nucleic acid binding transcription factor activity
1.28 1.72e-06 GO:0003700 sequence-specific DNA binding transcription factor activity
1.18 3.98e-36 GO:0005515 protein binding
1.08 7.96e-21 GO:0005488 binding