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Motif ID: NANOG.p2

Z-value: 1.139

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr4_+_77356252	2.136	NM_020859	SHROOM3	shroom family member 3
chr10_-_105845556	1.400		COL17A1	collagen, type XVII, alpha 1
chr10_-_105845619	1.380	NM_000494	COL17A1	collagen, type XVII, alpha 1
chr10_+_118187381	1.202	NM_001011709	PNLIPRP3	pancreatic lipase-related protein 3
chr6_-_136847078	1.154	NM_001198608 NM_001198609 NM_001198611	MAP7	microtubule-associated protein 7
chr9_+_12693385	1.108	NM_000550	TYRP1	tyrosinase-related protein 1
chr1_-_116383692	0.964	NM_005599	NHLH2	nescient helix loop helix 2
chr17_-_56494889	0.832		RNF43	ring finger protein 43
chr9_-_5304579	0.831	NM_005059 NM_134441	RLN2	relaxin 2
chr9_-_124984018	0.800	NM_001242335	LHX6	LIM homeobox 6
chr7_-_25268057	0.771	NM_022150	NPVF	neuropeptide VF precursor
chr12_-_52828105	0.736	NM_004693	KRT75	keratin 75
chr6_-_31107110	0.722	NM_014069	PSORS1C2	psoriasis susceptibility 1 candidate 2
chr18_+_29027731	0.719	NM_001944	DSG3	desmoglein 3
chr2_-_69098502	0.713	NM_014482	BMP10	bone morphogenetic protein 10
chr9_-_124989755	0.706	NM_001242334	LHX6	LIM homeobox 6
chr3_-_71778268	0.660	NM_001134650	EIF4E3	eukaryotic translation initiation factor 4E family member 3
chr8_+_32504250	0.660	NM_013959	NRG1	neuregulin 1
chr17_-_56494930	0.653	NM_017763	RNF43	ring finger protein 43
chr3_-_151034514	0.624	NM_023915	GPR87	G protein-coupled receptor 87
chr2_-_165424993	0.617		GRB14	growth factor receptor-bound protein 14
chr11_-_120008801	0.615		TRIM29	tripartite motif containing 29
chr11_-_85430117	0.613	NM_206929	SYTL2	synaptotagmin-like 2
chr3_+_159557649	0.591	NM_001197109	SCHIP1	schwannomin interacting protein 1
chr18_+_55888838	0.567		NEDD4L	neural precursor cell expressed, developmentally down-regulated 4-like
chr10_+_82173574	0.563	NM_001243778 NM_001243782	C10orf58	chromosome 10 open reading frame 58
chr12_-_52914080	0.560	NM_000424	KRT5	keratin 5
chr18_+_55888799	0.557		NEDD4L	neural precursor cell expressed, developmentally down-regulated 4-like
chr6_-_136847609	0.542		MAP7	microtubule-associated protein 7
chr9_-_5339745	0.540	NM_006911	RLN1	relaxin 1
chr8_-_40755328	0.530	NM_001135731 NM_024645	ZMAT4	zinc finger, matrin-type 4
chr5_-_35938736	0.530	NM_001042625 NM_144647	CAPSL	calcyphosine-like
chr12_+_47610244	0.527		FAM113B	family with sequence similarity 113, member B
chr17_-_38938785	0.510	NM_181537	KRT27	keratin 27
chr2_-_113594325	0.499	NM_000576	IL1B	interleukin 1, beta
chr14_-_81864726	0.497	NM_033104	STON2	stonin 2
chr3_+_111717585	0.496	NM_001008272 NM_013259	TAGLN3	transgelin 3
chr7_+_129015483	0.491	NM_001130722	AHCYL2	adenosylhomocysteinase-like 2
chr19_-_51522953	0.485	NM_145888	KLK10	kallikrein-related peptidase 10
chr1_-_23886284	0.472	NM_002167	ID3	inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
chr11_-_120008738	0.471		TRIM29	tripartite motif containing 29
chr1_+_160370363	0.458	NM_020335	VANGL2	vang-like 2 (van gogh, Drosophila)
chr1_-_42384326	0.455		HIVEP3	human immunodeficiency virus type I enhancer binding protein 3
chr12_-_16760935	0.447	NM_001001395 NM_001243609	LMO3	LIM domain only 3 (rhombotin-like 2)
chr20_+_2276612	0.422	NM_003245	TGM3	transglutaminase 3 (E polypeptide, protein-glutamine-gamma-glutamyltransferase)
chr7_-_41742666	0.418	NM_002192	INHBA	inhibin, beta A
chr1_+_35246789	0.382	NM_024009	GJB3	gap junction protein, beta 3, 31kDa
chr17_-_9694613	0.380	NM_001105571 NM_001220493	DHRS7C	dehydrogenase/reductase (SDR family) member 7C
chr10_-_123356158	0.379	NM_001144915	FGFR2	fibroblast growth factor receptor 2
chr3_+_159557745	0.378		SCHIP1	schwannomin interacting protein 1
chr11_-_85430382	0.369	NM_001162952 NM_206930	SYTL2	synaptotagmin-like 2
chr10_-_116444374	0.346	NM_001003407 NM_001003408	ABLIM1	actin binding LIM protein 1
chr11_-_58980321	0.342	NM_001039396	MPEG1	macrophage expressed 1
chr18_+_20735788	0.337	NM_138375	CABLES1	Cdk5 and Abl enzyme substrate 1
chr5_+_147258273	0.335	NM_054023	SCGB3A2	secretoglobin, family 3A, member 2
chr17_-_39165343	0.333	NM_031958	KRTAP3-1	keratin associated protein 3-1
chr18_+_55888750	0.325	NM_001144966	NEDD4L	neural precursor cell expressed, developmentally down-regulated 4-like
chrX_-_117107700	0.325	NM_033495 NM_001168300	KLHL13	kelch-like 13 (Drosophila)
chr12_-_15114495	0.321	NM_001175	ARHGDIB	Rho GDP dissociation inhibitor (GDI) beta
chr18_-_53089722	0.317	NM_001243233	TCF4	transcription factor 4
chr19_-_33360641	0.314	NM_001126335 NM_001243036 NM_014270	SLC7A9	solute carrier family 7 (glycoprotein-associated amino acid transporter light chain, bo,+ system), member 9
chrX_+_41306686	0.314	NM_022567	NYX	nyctalopin
chr1_-_94586678	0.311	NM_000350	ABCA4	ATP-binding cassette, sub-family A (ABC1), member 4
chr14_+_76837689	0.310	NM_004452	ESRRB	estrogen-related receptor beta
chr12_-_24103842	0.308		SOX5	SRY (sex determining region Y)-box 5
chr1_+_209878135	0.304	NM_005525	HSD11B1	hydroxysteroid (11-beta) dehydrogenase 1
chr12_+_47610051	0.302	NM_138371	FAM113B	family with sequence similarity 113, member B
chrX_-_48828250	0.299	NM_004979	KCND1	potassium voltage-gated channel, Shal-related subfamily, member 1
chr7_-_121944485	0.298	NM_001024613 NM_001160264	FEZF1	FEZ family zinc finger 1
chr1_+_84864214	0.296	NM_021233	DNASE2B	deoxyribonuclease II beta
chr10_+_24755459	0.295		KIAA1217	KIAA1217
chr12_-_57328044	0.292	NM_148897	SDR9C7	short chain dehydrogenase/reductase family 9C, member 7
chr10_+_49609641	0.289	NM_002750 NM_139046 NM_139047 NM_139049	MAPK8	mitogen-activated protein kinase 8
chr10_-_123353771	0.289	NM_001144916	FGFR2	fibroblast growth factor receptor 2
chr17_-_41739261	0.286	NM_001040002	MEOX1	mesenchyme homeobox 1
chr6_-_55740387	0.286		BMP5	bone morphogenetic protein 5
chr11_+_10476665	0.282	NM_001025389	AMPD3	adenosine monophosphate deaminase 3
chr7_-_37025696	0.280		ELMO1	engulfment and cell motility 1
chr4_-_159956332	0.274	NM_152543	C4orf45	chromosome 4 open reading frame 45
chr3_-_124842442	0.273		SLC12A8	solute carrier family 12 (potassium/chloride transporters), member 8
chr21_-_39956823	0.273	NM_001243429	ERG	v-ets erythroblastosis virus E26 oncogene homolog (avian)
chr7_+_94297448	0.269		PEG10	paternally expressed 10
chr6_+_90276556	0.267	NM_001242814	ANKRD6	ankyrin repeat domain 6
chr10_-_21435487	0.263	NM_001010896 NM_001177483	C10orf113	chromosome 10 open reading frame 113
chr12_-_110252600	0.258	NM_001177431 NM_001177428 NM_001177433 NM_147204	TRPV4	transient receptor potential cation channel, subfamily V, member 4
chr1_+_167298382	0.258		POU2F1	POU class 2 homeobox 1
chr11_-_120008848	0.254	NM_012101	TRIM29	tripartite motif containing 29
chr1_+_156119734	0.252	NM_001193301	SEMA4A	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
chr11_-_115088628	0.252		CADM1	cell adhesion molecule 1
chr12_-_89745997	0.249		DUSP6	dual specificity phosphatase 6
chr19_-_51523272	0.249	NM_002776 NM_001077500	KLK10	kallikrein-related peptidase 10
chr1_+_15256295	0.245	NM_001018001	KAZN	kazrin, periplakin interacting protein
chr1_+_151739130	0.244	NM_016178	OAZ3	ornithine decarboxylase antizyme 3
chr17_+_54230835	0.244	NM_153228	ANKFN1	ankyrin-repeat and fibronectin type III domain containing 1
chr3_-_120400957	0.241		HGD	homogentisate 1,2-dioxygenase
chr11_-_104916041	0.240	NM_001017534 NM_052889	CARD16	caspase recruitment domain family, member 16
chr8_-_27101240	0.239		STMN4	stathmin-like 4
chr3_-_74570262	0.236	NM_020872	CNTN3	contactin 3 (plasmacytoma associated)
chrX_+_41548225	0.234	NM_001097579 NM_005300	GPR34	G protein-coupled receptor 34
chr5_-_112630301	0.234		MCC	mutated in colorectal cancers
chr14_+_23305816	0.234		MMP14	matrix metallopeptidase 14 (membrane-inserted)
chr3_-_11623829	0.234	NM_001128220	VGLL4	vestigial like 4 (Drosophila)
chr5_+_52776479	0.234		FST	follistatin
chr16_+_57406398	0.234	NM_002996	CX3CL1	chemokine (C-X3-C motif) ligand 1
chr11_+_58390145	0.232	NM_000614	CNTF	ciliary neurotrophic factor
chr3_-_121379757	0.229	NM_005335	HCLS1	hematopoietic cell-specific Lyn substrate 1
chr5_+_36608430	0.228	NM_001166695	SLC1A3	solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr18_+_21572736	0.228	NM_153211	TTC39C	tetratricopeptide repeat domain 39C
chr8_+_26150731	0.226	NM_001177591	PPP2R2A	protein phosphatase 2, regulatory subunit B, alpha
chr19_-_51456159	0.225	NM_001077491 NM_001077492 NM_012427	KLK5	kallikrein-related peptidase 5
chr3_-_27764197	0.224		EOMES	eomesodermin
chrX_-_133792497	0.220	NM_021796	PLAC1	placenta-specific 1
chr4_-_123542165	0.219	NM_001207006 NM_021803	IL21	interleukin 21
chr7_+_114066554	0.218	NM_001172767 NM_148899	FOXP2	forkhead box P2
chr6_+_50786438	0.215	NM_003221	TFAP2B	transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
chr12_-_24103953	0.215		SOX5	SRY (sex determining region Y)-box 5
chr16_+_56815703	0.214	NM_001242795	NUP93	nucleoporin 93kDa
chr9_-_117156684	0.213	NM_030767	AKNA	AT-hook transcription factor
chr18_-_28742744	0.212	NM_004948 NM_024421	DSC1	desmocollin 1
chr12_-_89746244	0.211	NM_001946 NM_022652	DUSP6	dual specificity phosphatase 6
chr19_+_7968701	0.210		MAP2K7	mitogen-activated protein kinase kinase 7
chr21_+_43710190	0.207		ABCG1	ATP-binding cassette, sub-family G (WHITE), member 1
chr17_-_1248346	0.204		PAFAH1B1	platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
chr9_+_130026755	0.203	NM_032293	GARNL3	GTPase activating Rap/RanGAP domain-like 3
chr3_-_138478184	0.203	NM_006219	PIK3CB	phosphoinositide-3-kinase, catalytic, beta polypeptide
chr5_-_112630557	0.201	NM_002387	MCC	mutated in colorectal cancers
chr3_-_121379701	0.201		HCLS1	hematopoietic cell-specific Lyn substrate 1
chr4_+_78432905	0.199	NM_006419	CXCL13	chemokine (C-X-C motif) ligand 13
chr21_-_27945267	0.199	NM_052954	CYYR1	cysteine/tyrosine-rich 1
chr12_+_41831484	0.197	NM_013377	PDZRN4	PDZ domain containing ring finger 4
chr13_+_109281569	0.197	NM_001198950	MYO16	myosin XVI
chr1_+_16090993	0.189	NM_001024215	FBLIM1	filamin binding LIM protein 1
chr6_-_111927059	0.188		TRAF3IP2	TRAF3 interacting protein 2
chr1_+_6105980	0.188	NM_001199862	KCNAB2	potassium voltage-gated channel, shaker-related subfamily, beta member 2
chr20_+_43030005	0.188		HNF4A	hepatocyte nuclear factor 4, alpha
chr10_+_98740987	0.188	NM_015652	C10orf12	chromosome 10 open reading frame 12
chr17_-_39296702	0.187	NM_030976	KRTAP4-6	keratin associated protein 4-6
chr1_+_74701070	0.187	NM_015978	TNNI3K	TNNI3 interacting kinase
chr3_+_152880036	0.186		RAP2B	RAP2B, member of RAS oncogene family
chr12_+_81110689	0.185	NM_005593	MYF5	myogenic factor 5
chr18_+_61575203	0.182		SERPINB10	serpin peptidase inhibitor, clade B (ovalbumin), member 10
chr8_+_95653399	0.182		ESRP1	epithelial splicing regulatory protein 1
chr1_-_178840079	0.182	NM_004673	ANGPTL1	angiopoietin-like 1
chr6_-_55740358	0.178	NM_021073	BMP5	bone morphogenetic protein 5
chr5_+_170736287	0.178	NM_021025	TLX3	T-cell leukemia homeobox 3
chr2_+_234959345	0.177	NM_006944	SPP2	secreted phosphoprotein 2, 24kDa
chr6_+_129204285	0.174	NM_000426 NM_001079823	LAMA2	laminin, alpha 2
chr1_-_93399531	0.174
chr3_-_12941547	0.174		IQSEC1	IQ motif and Sec7 domain 1
chr3_-_57234279	0.173	NM_003865	HESX1	HESX homeobox 1
chr19_+_45409003	0.173	NM_000041	APOE	apolipoprotein E
chr1_-_154842725	0.172	NM_001204087 NM_002249	KCNN3	potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3
chr12_-_89746238	0.172		DUSP6	dual specificity phosphatase 6
chr5_-_148758787	0.171	NM_014443	IL17B	interleukin 17B
chr11_-_16424391	0.171	NM_001145819 NM_017508	SOX6	SRY (sex determining region Y)-box 6
chr7_+_18535351	0.170	NM_001204145 NM_001204146 NM_014707 NM_178423	HDAC9	histone deacetylase 9
chr14_+_23305792	0.170	NM_004995	MMP14	matrix metallopeptidase 14 (membrane-inserted)
chr9_-_117111278	0.169		AKNA	AT-hook transcription factor
chr6_+_143929316	0.168	NM_001100166 NM_014721	PHACTR2	phosphatase and actin regulator 2
chr12_-_52604488	0.166	NM_001242696	LOC283403	uncharacterized LOC283403
chr12_-_13103317	0.166	NM_018654	GPRC5D	G protein-coupled receptor, family C, group 5, member D
chr1_+_244216506	0.165	NM_006352	ZNF238	zinc finger protein 238
chr12_+_105153258	0.165		CHST11	carbohydrate (chondroitin 4) sulfotransferase 11
chr5_-_150467220	0.164	NM_001252390	TNIP1	TNFAIP3 interacting protein 1
chr12_-_16759733	0.162	NM_001243610	LMO3	LIM domain only 3 (rhombotin-like 2)
chr11_+_101983170	0.162	NM_001195045	YAP1	Yes-associated protein 1
chr3_-_108672547	0.162	NM_005459	GUCA1C	guanylate cyclase activator 1C
chr10_-_116444112	0.160		ABLIM1	actin binding LIM protein 1
chr3_-_143567163	0.159	NM_173653	SLC9A9	solute carrier family 9 (sodium/hydrogen exchanger), member 9
chr3_+_42190825	0.158		TRAK1	trafficking protein, kinesin binding 1
chr12_-_6486522	0.158	NM_001159575	SCNN1A	sodium channel, nonvoltage-gated 1 alpha
chr5_-_96478502	0.155	NM_153234	LIX1	Lix1 homolog (chicken)
chr6_-_13408368	0.155	NM_001242630	GFOD1	glucose-fructose oxidoreductase domain containing 1
chr4_-_153303663	0.155	NM_001013415	FBXW7	F-box and WD repeat domain containing 7
chr12_-_102874340	0.154		IGF1	insulin-like growth factor 1 (somatomedin C)
chr8_+_32579350	0.153	NM_001159996	NRG1	neuregulin 1
chr6_+_135502521	0.153		MYB	v-myb myeloblastosis viral oncogene homolog (avian)
chr8_-_42234562	0.152	NM_014420	DKK4	dickkopf homolog 4 (Xenopus laevis)
chr10_+_11206928	0.149	NM_001025076 NM_001083591	CELF2	CUGBP, Elav-like family member 2
chrX_-_33357725	0.148	NM_000109	DMD	dystrophin
chr7_-_129592711	0.147	NM_001202498	UBE2H	ubiquitin-conjugating enzyme E2H
chr11_-_83393436	0.146	NM_001142702	DLG2	discs, large homolog 2 (Drosophila)
chr9_+_136501484	0.146	NM_000787	DBH	dopamine beta-hydroxylase (dopamine beta-monooxygenase)
chr12_-_53730003	0.146	NM_001173467	SP7	Sp7 transcription factor
chr16_+_87984948	0.145	NM_001173539 NM_001173540 NM_001173541 NM_017869 NM_079837	BANP	BTG3 associated nuclear protein
chr2_-_180427314	0.144	NM_001113398	ZNF385B	zinc finger protein 385B
chr3_+_152880024	0.144	NM_002886	RAP2B	RAP2B, member of RAS oncogene family
chr10_-_72142344	0.143	NM_018205 NM_018239	LRRC20	leucine rich repeat containing 20
chr19_+_48325098	0.143	NM_000554	CRX	cone-rod homeobox
chr14_-_105259937	0.142	NM_005163	AKT1	v-akt murine thymoma viral oncogene homolog 1
chr1_+_43148048	0.139	NM_004559	YBX1	Y box binding protein 1
chr1_-_205391180	0.139	NM_001001552 NM_001199050 NM_001199051 NM_001199052	LEMD1	LEM domain containing 1
chr18_+_76740274	0.138	NM_171999	SALL3	sal-like 3 (Drosophila)
chr8_-_7287651	0.138	NM_018661	DEFB103B	defensin, beta 103B
chr21_-_31538970	0.138	NM_012131	CLDN17	claudin 17
chr13_+_32313678	0.137	NM_001166058 NM_130806	RXFP2	relaxin/insulin-like family peptide receptor 2
chr8_-_20040612	0.136	NM_001135691 NM_001142324 NM_001142325 NM_003053	SLC18A1	solute carrier family 18 (vesicular monoamine), member 1
chr2_+_102608305	0.136	NM_004633	IL1R2	interleukin 1 receptor, type II
chrX_+_105412297	0.136	NM_001171020 NM_152423	MUM1L1	melanoma associated antigen (mutated) 1-like 1
chr19_+_1026271	0.136	NM_004368 NM_201277	CNN2	calponin 2

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.60	8.92e-10	GO:0032502	developmental process
1.62	3.42e-09	GO:0007275	multicellular organismal development
1.46	4.97e-09	GO:0032501	multicellular organismal process
1.69	1.31e-08	GO:0048731	system development
1.63	3.97e-08	GO:0048856	anatomical structure development
1.85	1.19e-07	GO:0048513	organ development
2.14	4.64e-05	GO:0009891	positive regulation of biosynthetic process
2.14	6.16e-05	GO:0031328	positive regulation of cellular biosynthetic process
2.25	1.82e-04	GO:0010628	positive regulation of gene expression
2.53	1.95e-04	GO:0045944	positive regulation of transcription from RNA polymerase II promoter
2.29	2.77e-04	GO:0045893	positive regulation of transcription, DNA-dependent
2.18	8.43e-04	GO:0051254	positive regulation of RNA metabolic process
2.06	1.11e-03	GO:0051173	positive regulation of nitrogen compound metabolic process
2.08	1.44e-03	GO:0010557	positive regulation of macromolecule biosynthetic process
1.90	2.07e-03	GO:0006357	regulation of transcription from RNA polymerase II promoter
1.94	2.21e-03	GO:0050793	regulation of developmental process
1.78	2.29e-03	GO:0009893	positive regulation of metabolic process
3.23	2.33e-03	GO:0008544	epidermis development
2.04	2.41e-03	GO:0045935	positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.57	3.21e-03	GO:0030154	cell differentiation
1.94	4.17e-03	GO:0009888	tissue development
3.02	4.52e-03	GO:0007601	visual perception
3.02	4.52e-03	GO:0050953	sensory perception of light stimulus
3.19	5.11e-03	GO:0007517	muscle organ development
1.54	6.36e-03	GO:0048869	cellular developmental process
2.05	7.45e-03	GO:0045595	regulation of cell differentiation
2.49	7.69e-03	GO:0010551	regulation of gene-specific transcription from RNA polymerase II promoter
1.64	1.43e-02	GO:0007399	nervous system development
1.72	1.77e-02	GO:0031325	positive regulation of cellular metabolic process
3.26	1.88e-02	GO:0010552	positive regulation of gene-specific transcription from RNA polymerase II promoter
1.72	2.62e-02	GO:0010604	positive regulation of macromolecule metabolic process
4.99	4.77e-02	GO:0045834	positive regulation of lipid metabolic process

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
4.43	1.66e-03	GO:0045095	keratin filament
1.49	4.66e-03	GO:0005576	extracellular region
2.81	3.13e-02	GO:0005882	intermediate filament

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.80	2.46e-03	GO:0001071	nucleic acid binding transcription factor activity
1.80	2.46e-03	GO:0003700	sequence-specific DNA binding transcription factor activity