Motif ID: NANOG.p2

Z-value: 1.139


Transcription factors associated with NANOG.p2:

Gene SymbolEntrez IDGene Name
NANOG 79923 Nanog homeobox

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
NANOGchr12_+_79420250.676.8e-02Click!


Activity profile for motif NANOG.p2.

activity profile for motif NANOG.p2


Sorted Z-values histogram for motif NANOG.p2

Sorted Z-values for motif NANOG.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NANOG.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr4_+_77356252 2.136 NM_020859
 SHROOM3
shroom family member 3
chr10_-_105845556 1.400 COL17A1
collagen, type XVII, alpha 1
chr10_-_105845619 1.380 NM_000494
 COL17A1
collagen, type XVII, alpha 1
chr10_+_118187381 1.202 NM_001011709
 PNLIPRP3
pancreatic lipase-related protein 3
chr6_-_136847078 1.154 NM_001198608
NM_001198609
NM_001198611
 MAP7


microtubule-associated protein 7


chr9_+_12693385 1.108 NM_000550
 TYRP1
tyrosinase-related protein 1
chr1_-_116383692 0.964 NM_005599
 NHLH2
nescient helix loop helix 2
chr17_-_56494889 0.832 RNF43
ring finger protein 43
chr9_-_5304579 0.831 NM_005059
NM_134441
 RLN2

relaxin 2

chr9_-_124984018 0.800 NM_001242335
 LHX6
LIM homeobox 6
chr7_-_25268057 0.771 NM_022150
 NPVF
neuropeptide VF precursor
chr12_-_52828105 0.736 NM_004693
 KRT75
keratin 75
chr6_-_31107110 0.722 NM_014069
 PSORS1C2
psoriasis susceptibility 1 candidate 2
chr18_+_29027731 0.719 NM_001944
 DSG3
desmoglein 3
chr2_-_69098502 0.713 NM_014482
 BMP10
bone morphogenetic protein 10
chr9_-_124989755 0.706 NM_001242334
 LHX6
LIM homeobox 6
chr3_-_71778268 0.660 NM_001134650
 EIF4E3
eukaryotic translation initiation factor 4E family member 3
chr8_+_32504250 0.660 NM_013959
 NRG1
neuregulin 1
chr17_-_56494930 0.653 NM_017763
 RNF43
ring finger protein 43
chr3_-_151034514 0.624 NM_023915
 GPR87
G protein-coupled receptor 87

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 32 entries
enrichment   p-value GO term description
4.99 4.77e-02 GO:0045834 positive regulation of lipid metabolic process
3.26 1.88e-02 GO:0010552 positive regulation of gene-specific transcription from RNA polymerase II promoter
3.23 2.33e-03 GO:0008544 epidermis development
3.19 5.11e-03 GO:0007517 muscle organ development
3.02 4.52e-03 GO:0007601 visual perception
3.02 4.52e-03 GO:0050953 sensory perception of light stimulus
2.53 1.95e-04 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
2.49 7.69e-03 GO:0010551 regulation of gene-specific transcription from RNA polymerase II promoter
2.29 2.77e-04 GO:0045893 positive regulation of transcription, DNA-dependent
2.25 1.82e-04 GO:0010628 positive regulation of gene expression
2.18 8.43e-04 GO:0051254 positive regulation of RNA metabolic process
2.14 4.64e-05 GO:0009891 positive regulation of biosynthetic process
2.14 6.16e-05 GO:0031328 positive regulation of cellular biosynthetic process
2.08 1.44e-03 GO:0010557 positive regulation of macromolecule biosynthetic process
2.06 1.11e-03 GO:0051173 positive regulation of nitrogen compound metabolic process
2.05 7.45e-03 GO:0045595 regulation of cell differentiation
2.04 2.41e-03 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.94 2.21e-03 GO:0050793 regulation of developmental process
1.94 4.17e-03 GO:0009888 tissue development
1.90 2.07e-03 GO:0006357 regulation of transcription from RNA polymerase II promoter

Gene overrepresentation in compartment category:

Showing 1 to 3 of 3 entries
enrichment   p-value GO term description
4.43 1.66e-03 GO:0045095 keratin filament
2.81 3.13e-02 GO:0005882 intermediate filament
1.49 4.66e-03 GO:0005576 extracellular region

Gene overrepresentation in function category:

Showing 1 to 2 of 2 entries
enrichment   p-value GO term description
1.80 2.46e-03 GO:0001071 nucleic acid binding transcription factor activity
1.80 2.46e-03 GO:0003700 sequence-specific DNA binding transcription factor activity