Motif ID: NFE2L1.p2

Z-value: 0.830


Transcription factors associated with NFE2L1.p2:

Gene SymbolEntrez IDGene Name
NFE2L1 4779 nuclear factor (erythroid-derived 2)-like 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
NFE2L1chr17_+_461257250.911.6e-03Click!


Activity profile for motif NFE2L1.p2.

activity profile for motif NFE2L1.p2


Sorted Z-values histogram for motif NFE2L1.p2

Sorted Z-values for motif NFE2L1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NFE2L1.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr12_-_123187842 1.196 NM_177551
 HCAR2
hydroxycarboxylic acid receptor 2
chr12_-_123201319 1.026 NM_006018
 HCAR3
hydroxycarboxylic acid receptor 3
chr2_-_161056573 0.888 NM_000888
 ITGB6
integrin, beta 6
chr2_-_161056762 0.693 ITGB6
integrin, beta 6
chr9_+_127420690 0.675 MIR181A2HG
MIR181A2 host gene (non-protein coding)
chr5_+_148206155 0.623 NM_000024
 ADRB2
adrenergic, beta-2-, receptor, surface
chr20_+_62795773 0.582 MYT1
myelin transcription factor 1
chr12_+_41831484 0.582 NM_013377
 PDZRN4
PDZ domain containing ring finger 4
chr1_+_156254069 0.578 NM_032323
 TMEM79
transmembrane protein 79
chr12_-_52886971 0.571 NM_005554
 KRT6A
keratin 6A
chr11_-_5323174 0.536 NM_033179
 OR51B4
olfactory receptor, family 51, subfamily B, member 4
chr5_+_36608430 0.520 NM_001166695
 SLC1A3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr6_+_7541837 0.507 DSP
desmoplakin
chr12_-_67072881 0.500 NM_001178074
NM_021150
 GRIP1

glutamate receptor interacting protein 1

chr5_-_150948504 0.496 NM_001447
 FAT2
FAT tumor suppressor homolog 2 (Drosophila)
chr6_+_7541863 0.488 NM_001008844
NM_004415
 DSP

desmoplakin

chr5_+_147582338 0.481 NM_001195290
NM_205841
 SPINK6

serine peptidase inhibitor, Kazal type 6

chr20_-_23030141 0.481 NM_000361
 THBD
thrombomodulin
chr7_+_116660291 0.480 ST7
suppression of tumorigenicity 7
chr6_+_7541892 0.474 DSP
desmoplakin

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 24 entries
enrichment   p-value GO term description
1.95 2.99e-02 GO:0046034 ATP metabolic process
1.69 2.98e-03 GO:0016337 cell-cell adhesion
1.51 3.22e-02 GO:0071702 organic substance transport
1.45 1.54e-02 GO:0009887 organ morphogenesis
1.44 9.53e-04 GO:0007267 cell-cell signaling
1.42 3.53e-04 GO:0009611 response to wounding
1.40 5.50e-03 GO:0055085 transmembrane transport
1.39 6.23e-04 GO:0007154 cell communication
1.29 5.09e-03 GO:0009653 anatomical structure morphogenesis
1.27 1.50e-03 GO:0048513 organ development
1.24 6.83e-04 GO:0006950 response to stress
1.24 4.18e-03 GO:0065008 regulation of biological quality
1.21 3.23e-04 GO:0048856 anatomical structure development
1.21 7.88e-04 GO:0048731 system development
1.20 2.53e-03 GO:0051234 establishment of localization
1.19 8.99e-04 GO:0051179 localization
1.19 8.83e-03 GO:0006810 transport
1.18 1.34e-03 GO:0032502 developmental process
1.18 3.58e-03 GO:0007275 multicellular organismal development
1.17 5.82e-03 GO:0023052 signaling

Gene overrepresentation in compartment category:

Showing 1 to 20 of 24 entries
enrichment   p-value GO term description
1.81 3.02e-03 GO:0030424 axon
1.57 6.63e-04 GO:0043005 neuron projection
1.48 3.05e-04 GO:0030054 cell junction
1.42 1.17e-03 GO:0005789 endoplasmic reticulum membrane
1.42 1.19e-03 GO:0042175 nuclear membrane-endoplasmic reticulum network
1.41 1.39e-04 GO:0005626 insoluble fraction
1.41 7.10e-04 GO:0044432 endoplasmic reticulum part
1.40 5.47e-04 GO:0005624 membrane fraction
1.37 7.47e-05 GO:0005783 endoplasmic reticulum
1.36 1.61e-05 GO:0005887 integral to plasma membrane
1.36 9.42e-05 GO:0000267 cell fraction
1.36 2.49e-03 GO:0042995 cell projection
1.35 2.79e-05 GO:0031226 intrinsic to plasma membrane
1.34 5.65e-10 GO:0044459 plasma membrane part
1.27 4.50e-02 GO:0044430 cytoskeletal part
1.23 2.38e-02 GO:0005856 cytoskeleton
1.22 1.07e-13 GO:0016021 integral to membrane
1.22 1.91e-13 GO:0031224 intrinsic to membrane
1.19 1.43e-12 GO:0044425 membrane part
1.19 9.54e-04 GO:0043234 protein complex

Gene overrepresentation in function category:

Showing 1 to 20 of 21 entries
enrichment   p-value GO term description
3.04 1.11e-02 GO:0015296 anion:cation symporter activity
2.65 3.50e-02 GO:0003823 antigen binding
2.24 1.96e-02 GO:0005200 structural constituent of cytoskeleton
2.09 1.37e-02 GO:0015081 sodium ion transmembrane transporter activity
2.06 4.82e-02 GO:0015294 solute:cation symporter activity
1.98 1.80e-03 GO:0004386 helicase activity
1.97 1.07e-03 GO:0046873 metal ion transmembrane transporter activity
1.82 1.25e-03 GO:0005125 cytokine activity
1.82 1.27e-02 GO:0008083 growth factor activity
1.81 3.41e-02 GO:0008509 anion transmembrane transporter activity
1.62 1.10e-03 GO:0016887 ATPase activity
1.62 1.01e-02 GO:0042623 ATPase activity, coupled
1.58 3.56e-03 GO:0022804 active transmembrane transporter activity
1.58 4.25e-02 GO:0032403 protein complex binding
1.41 1.46e-04 GO:0022891 substrate-specific transmembrane transporter activity
1.40 1.68e-03 GO:0015075 ion transmembrane transporter activity
1.37 8.47e-04 GO:0022857 transmembrane transporter activity
1.33 4.98e-02 GO:0017111 nucleoside-triphosphatase activity
1.32 8.26e-03 GO:0022892 substrate-specific transporter activity
1.26 4.55e-02 GO:0005215 transporter activity