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Motif ID: NFE2L1.p2

Z-value: 0.830

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr12_-_123187842	1.196	NM_177551	HCAR2	hydroxycarboxylic acid receptor 2
chr12_-_123201319	1.026	NM_006018	HCAR3	hydroxycarboxylic acid receptor 3
chr2_-_161056573	0.888	NM_000888	ITGB6	integrin, beta 6
chr2_-_161056762	0.693		ITGB6	integrin, beta 6
chr9_+_127420690	0.675		MIR181A2HG	MIR181A2 host gene (non-protein coding)
chr5_+_148206155	0.623	NM_000024	ADRB2	adrenergic, beta-2-, receptor, surface
chr20_+_62795773	0.582		MYT1	myelin transcription factor 1
chr12_+_41831484	0.582	NM_013377	PDZRN4	PDZ domain containing ring finger 4
chr1_+_156254069	0.578	NM_032323	TMEM79	transmembrane protein 79
chr12_-_52886971	0.571	NM_005554	KRT6A	keratin 6A
chr11_-_5323174	0.536	NM_033179	OR51B4	olfactory receptor, family 51, subfamily B, member 4
chr5_+_36608430	0.520	NM_001166695	SLC1A3	solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr6_+_7541837	0.507		DSP	desmoplakin
chr12_-_67072881	0.500	NM_001178074 NM_021150	GRIP1	glutamate receptor interacting protein 1
chr5_-_150948504	0.496	NM_001447	FAT2	FAT tumor suppressor homolog 2 (Drosophila)
chr6_+_7541863	0.488	NM_001008844 NM_004415	DSP	desmoplakin
chr5_+_147582338	0.481	NM_001195290 NM_205841	SPINK6	serine peptidase inhibitor, Kazal type 6
chr20_-_23030141	0.481	NM_000361	THBD	thrombomodulin
chr7_+_116660291	0.480		ST7	suppression of tumorigenicity 7
chr6_+_7541892	0.474		DSP	desmoplakin
chr6_+_55039070	0.466	NM_001526	HCRTR2	hypocretin (orexin) receptor 2
chr11_-_124190092	0.465	NM_001002918	OR8D2	olfactory receptor, family 8, subfamily D, member 2
chr2_-_165477818	0.460		GRB14	growth factor receptor-bound protein 14
chr11_-_108464344	0.452	NM_015065	EXPH5	exophilin 5
chr12_-_105322056	0.448	NM_032148	SLC41A2	solute carrier family 41, member 2
chr12_+_104850762	0.441		CHST11	carbohydrate (chondroitin 4) sulfotransferase 11
chr12_+_104850784	0.438		CHST11	carbohydrate (chondroitin 4) sulfotransferase 11
chrX_+_105969875	0.438	NM_194463	RNF128	ring finger protein 128
chr2_-_165477986	0.425		GRB14	growth factor receptor-bound protein 14
chr12_+_104850986	0.424		CHST11	carbohydrate (chondroitin 4) sulfotransferase 11
chr11_+_6897855	0.418	NM_207186	OR10A4	olfactory receptor, family 10, subfamily A, member 4
chr17_+_34431219	0.416	NM_002984	CCL4	chemokine (C-C motif) ligand 4
chr8_+_95653399	0.409		ESRP1	epithelial splicing regulatory protein 1
chr16_+_69139466	0.394	NM_001199280	HAS3	hyaluronan synthase 3
chr5_+_166711842	0.390	NM_001122679	ODZ2	odz, odd Oz/ten-m homolog 2 (Drosophila)
chr12_-_46633551	0.388		SLC38A1	solute carrier family 38, member 1
chr2_-_165551178	0.380		COBLL1	COBL-like 1
chr8_+_95653340	0.378	NM_001034915 NM_001122825 NM_001122826 NM_001122827 NM_017697	ESRP1	epithelial splicing regulatory protein 1
chr19_-_36019194	0.372	NM_001166034 NM_001166035 NM_198538	SBSN	suprabasin
chr11_+_124120422	0.363	NM_001002905	OR8G1	olfactory receptor, family 8, subfamily G, member 1
chr12_+_78225068	0.362	NM_014903	NAV3	neuron navigator 3
chr8_+_32579350	0.355	NM_001159996	NRG1	neuregulin 1
chr4_-_123542165	0.353	NM_001207006 NM_021803	IL21	interleukin 21
chr7_+_116660263	0.353		ST7	suppression of tumorigenicity 7
chr9_+_27524311	0.350	NM_020124	IFNK	interferon, kappa
chr7_-_141646716	0.346	NM_013252	CLEC5A	C-type lectin domain family 5, member A
chr4_+_74606222	0.342	NM_000584	IL8	interleukin 8
chr17_-_38911524	0.337	NM_181534	KRT25	keratin 25
chr7_+_143701021	0.334	NM_001005281	OR6B1	olfactory receptor, family 6, subfamily B, member 1
chr1_-_242687997	0.333	NM_152666	PLD5	phospholipase D family, member 5
chr17_-_3301703	0.328	NM_003553	OR1E1	olfactory receptor, family 1, subfamily E, member 1
chr3_-_56809594	0.322	NM_001128616	ARHGEF3	Rho guanine nucleotide exchange factor (GEF) 3
chr17_+_72832064	0.313		TMEM104	transmembrane protein 104
chr8_+_95653272	0.312		ESRP1	epithelial splicing regulatory protein 1
chr5_-_16509106	0.308	NM_019000	FAM134B	family with sequence similarity 134, member B
chr18_+_47088400	0.303	NM_006033	LIPG	lipase, endothelial
chr8_-_145018904	0.302	NM_201381	PLEC	plectin
chr18_+_61554938	0.301	NM_001143818 NM_002575	SERPINB2	serpin peptidase inhibitor, clade B (ovalbumin), member 2
chr17_-_36981552	0.300	NM_017748	CWC25	CWC25 spliceosome-associated protein homolog (S. cerevisiae)
chr1_+_179965756	0.299		CEP350	centrosomal protein 350kDa
chr2_+_75061234	0.297		HK2	hexokinase 2
chr3_+_31574431	0.295		STT3B	STT3, subunit of the oligosaccharyltransferase complex, homolog B (S. cerevisiae)
chr16_-_71318761	0.294		FTSJD1	FtsJ methyltransferase domain containing 1
chr21_-_36421630	0.292		RUNX1	runt-related transcription factor 1
chr4_-_139163222	0.288	NM_014331	SLC7A11	solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
chr1_+_44064509	0.287		PTPRF	protein tyrosine phosphatase, receptor type, F
chr1_+_32050510	0.286		TINAGL1	tubulointerstitial nephritis antigen-like 1
chr2_+_68961912	0.283	NM_001007231 NM_001166277	ARHGAP25	Rho GTPase activating protein 25
chr10_+_82173574	0.280	NM_001243778 NM_001243782	C10orf58	chromosome 10 open reading frame 58
chr16_+_57662301	0.279	NM_001145771 NM_001145772 NM_001145773 NM_201524 NM_201525	GPR56	G protein-coupled receptor 56
chr4_-_128887092	0.273	NM_152778	MFSD8	major facilitator superfamily domain containing 8
chr13_+_113656076	0.271		MCF2L	MCF.2 cell line derived transforming sequence-like
chr12_-_58160823	0.271	NM_000785	CYP27B1	cytochrome P450, family 27, subfamily B, polypeptide 1
chr2_+_191301020	0.268		MFSD6	major facilitator superfamily domain containing 6
chr10_+_75673346	0.268		PLAU	plasminogen activator, urokinase
chr21_-_36421586	0.268	NM_001754	RUNX1	runt-related transcription factor 1
chr2_+_162272892	0.265		TBR1	T-box, brain, 1
chr12_-_18890917	0.264	NM_033123	PLCZ1	phospholipase C, zeta 1
chr1_-_217250230	0.263	NM_001243507 NM_001243509	ESRRG	estrogen-related receptor gamma
chr10_+_5566923	0.260	NM_005185	CALML3	calmodulin-like 3
chr17_-_29648631	0.260	NM_001003927 NM_014210	EVI2A	ecotropic viral integration site 2A
chr13_-_20805371	0.260	NM_006783	GJB6	gap junction protein, beta 6, 30kDa
chr5_+_145317297	0.255		SH3RF2	SH3 domain containing ring finger 2
chr2_-_142889269	0.255	NM_018557	LRP1B	low density lipoprotein receptor-related protein 1B
chr5_-_54281345	0.254	NM_001135604 NM_007036	ESM1	endothelial cell-specific molecule 1
chr12_+_101188373	0.251	NM_178826	ANO4	anoctamin 4
chr9_-_132515290	0.249	NM_004878	PTGES	prostaglandin E synthase
chr14_+_23842017	0.246	NM_172314 NM_022789	IL25	interleukin 25
chr1_-_200377262	0.246		ZNF281	zinc finger protein 281
chr3_+_1134619	0.246	NM_014461	CNTN6	contactin 6
chr14_-_35344852	0.244	NM_013448 NM_182648	BAZ1A	bromodomain adjacent to zinc finger domain, 1A
chr11_+_34642587	0.244	NM_001206615 NM_012153	EHF	ets homologous factor
chr2_-_46384	0.240	NM_001077710	FAM110C	family with sequence similarity 110, member C
chr17_-_39216343	0.238	NM_001165252	LOC730755	keratin associated protein 2-4-like
chr10_-_65028825	0.237	NM_004241	JMJD1C	jumonji domain containing 1C
chrX_-_49965657	0.237	NM_003886	AKAP4	A kinase (PRKA) anchor protein 4
chr18_+_29027731	0.236	NM_001944	DSG3	desmoglein 3
chr1_+_40420781	0.234	NM_001136493 NM_032793	MFSD2A	major facilitator superfamily domain containing 2A
chr12_+_69139958	0.233		SLC35E3	solute carrier family 35, member E3
chr2_+_148602569	0.232	NM_001616	ACVR2A	activin A receptor, type IIA
chr2_+_69001932	0.232	NM_001166276 NM_014882	ARHGAP25	Rho GTPase activating protein 25
chr2_-_38525527	0.231		ATL2	atlastin GTPase 2
chr21_-_36421578	0.231		RUNX1	runt-related transcription factor 1
chr6_-_11779279	0.225	NM_001143948 NM_032744	C6orf105	chromosome 6 open reading frame 105
chr4_+_85504056	0.225	NM_001263	CDS1	CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1
chr12_+_18891040	0.222	NM_033328	CAPZA3	capping protein (actin filament) muscle Z-line, alpha 3
chr1_-_217262946	0.215	NM_001243506 NM_206594 NM_206595	ESRRG	estrogen-related receptor gamma
chr1_-_209824641	0.215	NM_001017402	LAMB3	laminin, beta 3
chr3_-_48601200	0.214	NM_033199	UCN2	urocortin 2
chrX_+_138612894	0.213	NM_000133	F9	coagulation factor IX
chr12_+_12224401	0.213	NM_030766 NM_138722	BCL2L14	BCL2-like 14 (apoptosis facilitator)
chr1_+_86889768	0.213	NM_006536	CLCA2	chloride channel accessory 2
chr16_+_24802421	0.211		TNRC6A	trinucleotide repeat containing 6A
chr6_+_44195008	0.210		SLC29A1	solute carrier family 29 (nucleoside transporters), member 1
chr4_-_164534656	0.209	NM_017923	MARCH1	membrane-associated ring finger (C3HC4) 1
chr7_-_102920665	0.208		DPY19L2P2	dpy-19-like 2 pseudogene 2 (C. elegans)
chr12_+_107712151	0.207	NM_001018072	BTBD11	BTB (POZ) domain containing 11
chr17_-_46608271	0.206	NM_002144	HOXB1	homeobox B1
chr12_-_10962673	0.205	NM_023917	TAS2R9	taste receptor, type 2, member 9
chr7_+_26242007	0.205
chrM_+_9217	0.202
chr3_+_121774208	0.202	NM_001206924 NM_001206925 NM_175862	CD86	CD86 molecule
chr16_+_82660390	0.201	NM_001220488 NM_001220489 NM_001220490 NM_001220491 NM_001220492 NM_001257	CDH13	cadherin 13, H-cadherin (heart)
chr15_+_89739234	0.201		ABHD2	abhydrolase domain containing 2
chr14_+_64682671	0.200	NM_182910	SYNE2	spectrin repeat containing, nuclear envelope 2
chr12_-_71148063	0.199		PTPRR	protein tyrosine phosphatase, receptor type, R
chr11_+_117947726	0.196	NM_001083947 NM_001173551 NM_001173552 NM_019894	TMPRSS4	transmembrane protease, serine 4
chr8_+_99129488	0.196	NM_001145860 NM_001145861	POP1	processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae)
chr11_-_124310980	0.195	NM_012378	OR8B8	olfactory receptor, family 8, subfamily B, member 8
chr4_+_30722445	0.195		PCDH7	protocadherin 7
chr12_-_14849427	0.195	NM_004963	GUCY2C	guanylate cyclase 2C (heat stable enterotoxin receptor)
chr12_-_90049818	0.194	NM_001001323 NM_001682	ATP2B1	ATPase, Ca++ transporting, plasma membrane 1
chr15_+_92397563	0.193		SLCO3A1	solute carrier organic anion transporter family, member 3A1
chr9_-_34048869	0.193		UBAP2	ubiquitin associated protein 2
chr22_+_29449877	0.192		ZNRF3	zinc and ring finger 3
chr4_+_74735107	0.191	NM_001511	CXCL1	chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
chr22_+_42229105	0.190	NM_004599	SREBF2	sterol regulatory element binding transcription factor 2
chrM_+_9182	0.190
chr17_-_49124128	0.189	NM_001251971	SPAG9	sperm associated antigen 9
chr1_+_40420802	0.189		MFSD2A	major facilitator superfamily domain containing 2A
chr7_+_73245192	0.189	NM_001305	CLDN4	claudin 4
chr6_+_143382030	0.189		AIG1	androgen-induced 1
chr1_-_154840460	0.188
chr2_+_204801453	0.188	NM_012092	ICOS	inducible T-cell co-stimulator
chr7_-_83824216	0.188	NM_006080	SEMA3A	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chrM_+_8857	0.188
chr16_-_87903028	0.187	NM_003486	SLC7A5	solute carrier family 7 (amino acid transporter light chain, L system), member 5
chr1_+_27101217	0.187		ARID1A	AT rich interactive domain 1A (SWI-like)
chr16_+_28986024	0.186	NM_001142448 NM_001142449 NM_001142450 NM_001142451 NM_032038	SPIN1 SPNS1	spindlin 1 spinster homolog 1 (Drosophila)
chrX_-_100662905	0.186	NM_000169	GLA	galactosidase, alpha
chr7_+_123249076	0.186	NM_080928	ASB15	ankyrin repeat and SOCS box containing 15
chr4_-_80994309	0.185	NM_001145794 NM_058172	ANTXR2	anthrax toxin receptor 2
chr10_+_90424145	0.184	NM_001198828 NM_001198829 NM_001198830 NM_004190	LIPF	lipase, gastric
chr5_+_52284903	0.184	NM_002203	ITGA2	integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
chr15_-_72612497	0.182	NM_052840	CELF6	CUGBP, Elav-like family member 6
chr7_+_128312345	0.181	NM_001012454 NM_001128926	FAM71F2	family with sequence similarity 71, member F2
chr17_-_3337134	0.181	NM_003554	OR1E2	olfactory receptor, family 1, subfamily E, member 2
chr14_-_95599794	0.179	NM_001195573	DICER1	dicer 1, ribonuclease type III
chr19_-_19774501	0.179	NM_020410	ATP13A1	ATPase type 13A1
chr16_-_58328879	0.178	NM_001080492	PRSS54	protease, serine, 54
chr11_+_117947785	0.177		TMPRSS4	transmembrane protease, serine 4
chr12_+_81101407	0.177	NM_002469	MYF6	myogenic factor 6 (herculin)
chr11_-_11643542	0.177	NM_198516	GALNTL4	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 4
chr17_-_47785527	0.176		SLC35B1	solute carrier family 35, member B1
chrX_-_110654373	0.176	NM_000555	DCX	doublecortin
chr15_+_34394273	0.175	NM_152595	PGBD4	piggyBac transposable element derived 4
chr9_-_34048887	0.175	NM_018449	UBAP2	ubiquitin associated protein 2
chr5_-_77805930	0.175		LHFPL2	lipoma HMGIC fusion partner-like 2
chr21_+_34922923	0.174		SON	SON DNA binding protein
chr2_+_169757749	0.173	NM_001081686 NM_021176	G6PC2	glucose-6-phosphatase, catalytic, 2
chr20_+_9458460	0.172		PLCB4	phospholipase C, beta 4
chr7_-_6474584	0.171		DAGLB	diacylglycerol lipase, beta
chr6_+_160327972	0.171	NM_002377	MAS1	MAS1 oncogene
chr17_+_57784961	0.171		VMP1	vacuole membrane protein 1
chr15_+_40509628	0.170	NM_001128628 NM_001128629	PAK6	p21 protein (Cdc42/Rac)-activated kinase 6
chr12_-_95611023	0.170	NM_018351	FGD6	FYVE, RhoGEF and PH domain containing 6
chr7_+_107221203	0.169	NM_001008405	BCAP29	B-cell receptor-associated protein 29
chr17_+_57785011	0.169		VMP1	vacuole membrane protein 1
chr19_-_19774472	0.169		ATP13A1	ATPase type 13A1
chrX_-_33357725	0.168	NM_000109	DMD	dystrophin
chr4_-_41750936	0.168	NM_003924	PHOX2B	paired-like homeobox 2b
chrM_+_5245	0.168
chr8_+_23386362	0.168	NM_016612	SLC25A37	solute carrier family 25, member 37
chrX_+_17393537	0.168	NM_198270	NHS	Nance-Horan syndrome (congenital cataracts and dental anomalies)
chr4_-_74964996	0.167	NM_002089	CXCL2	chemokine (C-X-C motif) ligand 2
chr1_-_205819244	0.167	NM_152491	PM20D1	peptidase M20 domain containing 1
chrX_-_100662788	0.166		GLA	galactosidase, alpha
chr16_+_2563977	0.166		ATP6V0C	ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c
chr17_+_57785025	0.165		VMP1	vacuole membrane protein 1
chr1_-_155210887	0.164		GBA	glucosidase, beta, acid
chr16_+_2563993	0.164		ATP6V0C	ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c
chr11_-_16424391	0.164	NM_001145819 NM_017508	SOX6	SRY (sex determining region Y)-box 6
chr3_+_184097860	0.164	NM_003741	CHRD	chordin
chr16_+_2563914	0.162		ATP6V0C	ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c
chr20_-_14318200	0.161	NM_013281 NM_198391	FLRT3	fibronectin leucine rich transmembrane protein 3
chr7_-_41742666	0.159	NM_002192	INHBA	inhibin, beta A
chr3_-_54961961	0.159	NM_020678	LRTM1	leucine-rich repeats and transmembrane domains 1
chr19_+_7968774	0.159		MAP2K7	mitogen-activated protein kinase kinase 7
chr2_-_31352489	0.158	NM_001253827	GALNT14	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 14 (GalNAc-T14)
chr11_-_1016736	0.157		MUC6	mucin 6, oligomeric mucus/gel-forming

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.09	6.82e-08	GO:0009987	cellular process
1.21	3.23e-04	GO:0048856	anatomical structure development
1.42	3.53e-04	GO:0009611	response to wounding
1.13	4.35e-04	GO:0050896	response to stimulus
1.39	6.23e-04	GO:0007154	cell communication
1.24	6.83e-04	GO:0006950	response to stress
1.21	7.88e-04	GO:0048731	system development
1.19	8.99e-04	GO:0051179	localization
1.44	9.53e-04	GO:0007267	cell-cell signaling
1.18	1.34e-03	GO:0032502	developmental process
1.27	1.50e-03	GO:0048513	organ development
1.10	2.19e-03	GO:0065007	biological regulation
1.20	2.53e-03	GO:0051234	establishment of localization
1.69	2.98e-03	GO:0016337	cell-cell adhesion
1.18	3.58e-03	GO:0007275	multicellular organismal development
1.24	4.18e-03	GO:0065008	regulation of biological quality
1.13	4.65e-03	GO:0032501	multicellular organismal process
1.29	5.09e-03	GO:0009653	anatomical structure morphogenesis
1.40	5.50e-03	GO:0055085	transmembrane transport
1.17	5.82e-03	GO:0023052	signaling
1.19	8.83e-03	GO:0006810	transport
1.45	1.54e-02	GO:0009887	organ morphogenesis
1.95	2.99e-02	GO:0046034	ATP metabolic process
1.51	3.22e-02	GO:0071702	organic substance transport

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.22	1.07e-13	GO:0016021	integral to membrane
1.22	1.91e-13	GO:0031224	intrinsic to membrane
1.19	1.43e-12	GO:0044425	membrane part
1.34	5.65e-10	GO:0044459	plasma membrane part
1.14	2.24e-09	GO:0016020	membrane
1.36	1.61e-05	GO:0005887	integral to plasma membrane
1.18	1.73e-05	GO:0071944	cell periphery
1.35	2.79e-05	GO:0031226	intrinsic to plasma membrane
1.17	2.87e-05	GO:0005886	plasma membrane
1.37	7.47e-05	GO:0005783	endoplasmic reticulum
1.36	9.42e-05	GO:0000267	cell fraction
1.41	1.39e-04	GO:0005626	insoluble fraction
1.48	3.05e-04	GO:0030054	cell junction
1.40	5.47e-04	GO:0005624	membrane fraction
1.57	6.63e-04	GO:0043005	neuron projection
1.41	7.10e-04	GO:0044432	endoplasmic reticulum part
1.19	9.54e-04	GO:0043234	protein complex
1.42	1.17e-03	GO:0005789	endoplasmic reticulum membrane
1.42	1.19e-03	GO:0042175	nuclear membrane-endoplasmic reticulum network
1.36	2.49e-03	GO:0042995	cell projection
1.81	3.02e-03	GO:0030424	axon
1.23	2.38e-02	GO:0005856	cytoskeleton
1.10	3.80e-02	GO:0044422	organelle part
1.27	4.50e-02	GO:0044430	cytoskeletal part

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.41	1.46e-04	GO:0022891	substrate-specific transmembrane transporter activity
1.37	8.47e-04	GO:0022857	transmembrane transporter activity
1.97	1.07e-03	GO:0046873	metal ion transmembrane transporter activity
1.62	1.10e-03	GO:0016887	ATPase activity
1.82	1.25e-03	GO:0005125	cytokine activity
1.10	1.43e-03	GO:0005515	protein binding
1.40	1.68e-03	GO:0015075	ion transmembrane transporter activity
1.98	1.80e-03	GO:0004386	helicase activity
1.58	3.56e-03	GO:0022804	active transmembrane transporter activity
1.32	8.26e-03	GO:0022892	substrate-specific transporter activity
1.62	1.01e-02	GO:0042623	ATPase activity, coupled
3.04	1.11e-02	GO:0015296	anion:cation symporter activity
1.82	1.27e-02	GO:0008083	growth factor activity
2.09	1.37e-02	GO:0015081	sodium ion transmembrane transporter activity
2.24	1.96e-02	GO:0005200	structural constituent of cytoskeleton
1.81	3.41e-02	GO:0008509	anion transmembrane transporter activity
2.65	3.50e-02	GO:0003823	antigen binding
1.58	4.25e-02	GO:0032403	protein complex binding
1.26	4.55e-02	GO:0005215	transporter activity
2.06	4.82e-02	GO:0015294	solute:cation symporter activity
1.33	4.98e-02	GO:0017111	nucleoside-triphosphatase activity