Motif ID: NFY{A,B,C}.p2

Z-value: 3.664


Transcription factors associated with NFY{A,B,C}.p2:

Gene SymbolEntrez IDGene Name
NFYA 4800 nuclear transcription factor Y, alpha
NFYB 4801 nuclear transcription factor Y, beta
NFYC 4802 nuclear transcription factor Y, gamma

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
NFYCchr1_+_412045090.865.5e-03Click!
NFYAchr6_+_410406870.865.9e-03Click!
NFYBchr12_-_1045318750.512.0e-01Click!


Activity profile for motif NFY{A,B,C}.p2.

activity profile for motif NFY{A,B,C}.p2


Sorted Z-values histogram for motif NFY{A,B,C}.p2

Sorted Z-values for motif NFY{A,B,C}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NFY{A,B,C}.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_-_2263706 5.412 NM_006454
MXD4
MAX dimerization protein 4
chr4_-_2263808 5.210 MXD4
MAX dimerization protein 4
chr6_-_167040700 5.128 NM_021135
RPS6KA2
ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr6_-_167040506 4.815 RPS6KA2
ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr6_-_167040659 4.759 RPS6KA2
ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr1_+_145438437 3.590 NM_006472
TXNIP
thioredoxin interacting protein
chr1_+_221052845 3.249 HLX
H2.0-like homeobox
chr1_+_221052735 3.213 NM_021958
HLX
H2.0-like homeobox
chr1_-_46598250 3.078 NM_003629
NM_001114172
PIK3R3

phosphoinositide-3-kinase, regulatory subunit 3 (gamma)

chr14_-_74551073 3.014 ALDH6A1
aldehyde dehydrogenase 6 family, member A1
chr1_-_182360889 2.942 GLUL
glutamate-ammonia ligase
chr14_-_52535765 2.831 NID2
nidogen 2 (osteonidogen)
chr1_-_150602047 2.806 ENSA
endosulfine alpha
chr7_+_94024201 2.768 COL1A2
collagen, type I, alpha 2
chr14_-_74551159 2.673 NM_005589
ALDH6A1
aldehyde dehydrogenase 6 family, member A1
chr14_-_52535711 2.623 NID2
nidogen 2 (osteonidogen)
chr1_+_163038934 2.568 NM_001113381
RGS4
regulator of G-protein signaling 4
chr12_-_6665220 2.530 NM_001039670
NM_001193457
NM_080730
IFFO1


intermediate filament family orphan 1


chr17_+_6347733 2.454 NM_001195228
NM_019013
FAM64A

family with sequence similarity 64, member A

chr8_+_97506020 2.437 SDC2
syndecan 2
chr1_-_150602089 2.389 NM_004436
NM_207042
NM_207043
NM_207044
NM_207168
ENSA




endosulfine alpha




chr14_-_61115906 2.375 NM_005982
SIX1
SIX homeobox 1
chr3_+_8543508 2.373 NM_014583
LMCD1
LIM and cysteine-rich domains 1
chr14_-_52535737 2.356 NID2
nidogen 2 (osteonidogen)
chr3_-_185826748 2.330 NM_004454
ETV5
ets variant 5
chr8_+_97506071 2.324 SDC2
syndecan 2
chr14_-_52535945 2.290 NM_007361
NID2
nidogen 2 (osteonidogen)
chr8_+_97506141 2.265 SDC2
syndecan 2
chr7_+_94023872 2.208 NM_000089
COL1A2
collagen, type I, alpha 2
chr10_-_93392857 2.171 NM_005398
PPP1R3C
protein phosphatase 1, regulatory subunit 3C
chr1_+_221053000 2.116 HLX
H2.0-like homeobox
chr5_-_19988293 2.066 NM_001167667
NM_004934
CDH18

cadherin 18, type 2

chr1_-_150602020 2.043 ENSA
endosulfine alpha
chr11_-_63381907 2.036 NM_007069
PLA2G16
phospholipase A2, group XVI
chr1_-_150601554 2.019 NM_207045
NM_207046
NM_207047
ENSA


endosulfine alpha


chr5_-_172755418 2.013 STC2
stanniocalcin 2
chr8_+_97505895 1.999 SDC2
syndecan 2
chr8_+_97505876 1.989 NM_002998
SDC2
syndecan 2
chr5_+_40680042 1.979 PTGER4
prostaglandin E receptor 4 (subtype EP4)
chr12_+_108909049 1.970 NM_007076
FICD
FIC domain containing
chrX_+_16964730 1.970 NM_001080975
NM_004726
REPS2

RALBP1 associated Eps domain containing 2

chr5_-_172755195 1.941 STC2
stanniocalcin 2
chr10_-_28591844 1.907 MPP7
membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7)
chr1_-_150601911 1.906 ENSA
endosulfine alpha
chr11_-_63381840 1.861 PLA2G16
phospholipase A2, group XVI
chr5_-_92916924 1.783 FLJ42709
uncharacterized LOC441094
chr1_+_89990396 1.779 NM_001134476
LRRC8B
leucine rich repeat containing 8 family, member B
chr10_-_93392744 1.754 PPP1R3C
protein phosphatase 1, regulatory subunit 3C
chr20_-_30311693 1.750 BCL2L1
BCL2-like 1
chr16_-_1876528 1.724 HAGH
hydroxyacylglutathione hydrolase
chr17_-_48278874 1.715 COL1A1
collagen, type I, alpha 1
chr1_+_213123853 1.710 NM_001136474
NM_001136475
NM_024749
VASH2


vasohibin 2


chr2_-_73460326 1.704 NM_032319
PRADC1
protease-associated domain containing 1
chr9_+_34329503 1.695 NM_001161
NM_001244390
NM_147172
NM_147173
NUDT2



nudix (nucleoside diphosphate linked moiety X)-type motif 2



chr5_-_149535420 1.666 NM_002609
PDGFRB
platelet-derived growth factor receptor, beta polypeptide
chr2_-_239148626 1.658 NM_001142853
NM_018645
HES6

hairy and enhancer of split 6 (Drosophila)

chr5_-_149535138 1.656 PDGFRB
platelet-derived growth factor receptor, beta polypeptide
chr2_-_239148545 1.641 HES6
hairy and enhancer of split 6 (Drosophila)
chr12_+_51818669 1.596 SLC4A8
solute carrier family 4, sodium bicarbonate cotransporter, member 8
chr7_+_149571029 1.573 ATP6V0E2
ATPase, H+ transporting V0 subunit e2
chrX_-_62975005 1.570 NM_001173480
NM_015185
ARHGEF9

Cdc42 guanine nucleotide exchange factor (GEF) 9

chr1_-_182361311 1.568 NM_001033044
NM_002065
GLUL

glutamate-ammonia ligase

chr3_+_8543539 1.548 LMCD1
LIM and cysteine-rich domains 1
chr6_+_52529157 1.527 LOC730101
uncharacterized LOC730101
chr5_-_149535309 1.523 PDGFRB
platelet-derived growth factor receptor, beta polypeptide
chr16_-_1877140 1.480 NM_001040427
NM_005326
HAGH

hydroxyacylglutathione hydrolase

chr5_+_151151483 1.476 G3BP1
GTPase activating protein (SH3 domain) binding protein 1
chr15_+_41625152 1.464 NUSAP1
nucleolar and spindle associated protein 1
chr5_+_40680021 1.460 NM_000958
PTGER4
prostaglandin E receptor 4 (subtype EP4)
chr13_-_33859835 1.455 NM_178006
STARD13
StAR-related lipid transfer (START) domain containing 13
chr14_+_54863672 1.453 NM_001130851
NM_005192
CDKN3

cyclin-dependent kinase inhibitor 3

chr17_+_48172508 1.446 NM_001199900
NM_002611
NM_001199899
PDK2


pyruvate dehydrogenase kinase, isozyme 2


chr7_+_152161119 1.426 LOC100128822
uncharacterized LOC100128822
chr17_-_48278987 1.418 NM_000088
COL1A1
collagen, type I, alpha 1
chr20_-_45985411 1.414 NM_012408
NM_183047
NM_183048
ZMYND8


zinc finger, MYND-type containing 8


chrX_-_62974987 1.414 ARHGEF9
Cdc42 guanine nucleotide exchange factor (GEF) 9
chr19_+_1104068 1.369 GPX4
glutathione peroxidase 4 (phospholipid hydroperoxidase)
chr13_-_67804432 1.367 NM_020403
NM_203487
PCDH9

protocadherin 9

chr9_-_35815040 1.357 NM_032593
HINT2
histidine triad nucleotide binding protein 2
chr17_-_56595192 1.347 NM_004687
MTMR4
myotubularin related protein 4
chr1_+_159750756 1.343 NM_017823
DUSP23
dual specificity phosphatase 23
chr11_+_64879294 1.341 NM_003273
TM7SF2
transmembrane 7 superfamily member 2
chrX_-_15872921 1.340 AP1S2
adaptor-related protein complex 1, sigma 2 subunit
chr19_+_1104007 1.338 GPX4
glutathione peroxidase 4 (phospholipid hydroperoxidase)
chr9_-_35814997 1.336 HINT2
histidine triad nucleotide binding protein 2
chr1_-_27816667 1.336 WASF2
WAS protein family, member 2
chr5_-_137090049 1.326


chrX_-_15872905 1.325


chr11_-_67275549 1.320 CDK2AP2
cyclin-dependent kinase 2 associated protein 2
chr12_+_51818592 1.318 NM_001039960
NM_004858
SLC4A8

solute carrier family 4, sodium bicarbonate cotransporter, member 8

chr7_-_137686778 1.303 CREB3L2
cAMP responsive element binding protein 3-like 2
chr2_+_27274520 1.297 AGBL5
ATP/GTP binding protein-like 5
chr11_-_63381940 1.291 NM_001128203
PLA2G16
phospholipase A2, group XVI
chr19_+_1269244 1.289 NM_001280
CIRBP
cold inducible RNA binding protein
chr7_+_74306895 1.289 PMS2P5
postmeiotic segregation increased 2 pseudogene 5
chr17_+_72744775 1.288 SLC9A3R1
solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1
chr5_-_179780314 1.282 NM_005110
GFPT2
glutamine-fructose-6-phosphate transaminase 2
chr5_-_150138081 1.275 NM_001135644
DCTN4
dynactin 4 (p62)
chr1_-_95392501 1.252 NM_001839
CNN3
calponin 3, acidic
chr20_+_33292117 1.250 NM_021202
TP53INP2
tumor protein p53 inducible nuclear protein 2
chr2_+_191745791 1.249 GLS
glutaminase
chr22_-_19435211 1.246 C22orf39
HIRA
chromosome 22 open reading frame 39
HIR histone cell cycle regulation defective homolog A (S. cerevisiae)
chr16_-_1832571 1.242 SPSB3
splA/ryanodine receptor domain and SOCS box containing 3
chr11_-_119293848 1.240 THY1
Thy-1 cell surface antigen
chr7_+_129710401 1.239 KLHDC10
kelch domain containing 10
chrX_-_101771641 1.238 NM_021992
TMSB15A
TMSB15B
thymosin beta 15a
thymosin beta 15B
chr12_-_110011286 1.237 NM_052845
MMAB
methylmalonic aciduria (cobalamin deficiency) cblB type
chr17_+_72744794 1.234 SLC9A3R1
solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1
chr7_-_137531585 1.232 NM_004717
DGKI
diacylglycerol kinase, iota
chr3_-_186288331 1.225 NM_001134415
TBCCD1
TBCC domain containing 1
chr19_-_14228362 1.212 NM_002730
PRKACA
protein kinase, cAMP-dependent, catalytic, alpha
chr4_-_7044664 1.209 NM_153376
CCDC96
coiled-coil domain containing 96
chr5_+_148737569 1.203 NM_024028
PCYOX1L
prenylcysteine oxidase 1 like
chr16_-_1876792 1.200 HAGH
hydroxyacylglutathione hydrolase
chr1_-_31345361 1.193 SDC3
syndecan 3
chr5_+_148737613 1.191 PCYOX1L
prenylcysteine oxidase 1 like
chr2_-_45236521 1.184 NM_016932
SIX2
SIX homeobox 2
chr17_+_4613931 1.175 ARRB2
arrestin, beta 2
chrX_+_30671602 1.174 GK
glycerol kinase
chr3_-_197686837 1.157 NM_032263
IQCG
IQ motif containing G
chrX_+_30671537 1.156 GK
glycerol kinase
chr2_+_27274490 1.154 NM_001035507
NM_021831
AGBL5

ATP/GTP binding protein-like 5

chr16_-_2264776 1.150 NM_001042371
PGP
phosphoglycolate phosphatase
chr17_+_72744746 1.147 NM_004252
SLC9A3R1
solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1
chr7_+_99102272 1.145 NM_145102
ZKSCAN5
zinc finger with KRAB and SCAN domains 5
chr7_+_99102572 1.140 NM_014569
ZKSCAN5
zinc finger with KRAB and SCAN domains 5
chr19_+_50031232 1.138 RCN3
reticulocalbin 3, EF-hand calcium binding domain
chr17_-_74236272 1.134 NM_052916
RNF157
ring finger protein 157
chrX_-_62974942 1.133 ARHGEF9
Cdc42 guanine nucleotide exchange factor (GEF) 9
chr14_+_24584467 1.131 NM_181357
DCAF11
DDB1 and CUL4 associated factor 11
chr17_+_58755158 1.124 NM_001099432
NM_017679
BCAS3

breast carcinoma amplified sequence 3

chr1_-_182360400 1.121 NM_001033056
GLUL
glutamate-ammonia ligase
chr14_-_53019036 1.119 NM_001160047
NM_020784
TXNDC16

thioredoxin domain containing 16

chr14_+_24583905 1.118 NM_001163484
DCAF11
DDB1 and CUL4 associated factor 11
chr17_+_46970128 1.115 NM_001002027
NM_005175
ATP5G1

ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9)

chr11_-_119294242 1.105 NM_006288
THY1
Thy-1 cell surface antigen
chr19_+_41770349 1.102 HNRNPUL1
heterogeneous nuclear ribonucleoprotein U-like 1
chr11_-_73694297 1.096 UCP2
uncoupling protein 2 (mitochondrial, proton carrier)
chr1_-_150602041 1.093 ENSA
endosulfine alpha
chr7_-_137686812 1.090 CREB3L2
cAMP responsive element binding protein 3-like 2
chr5_-_137090033 1.090 HNRNPA0
heterogeneous nuclear ribonucleoprotein A0
chr14_+_24583979 1.090 NM_025230
DCAF11
DDB1 and CUL4 associated factor 11
chr9_-_20622476 1.088 NM_004529
MLLT3
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
chrX_-_15872882 1.084 AP1S2
adaptor-related protein complex 1, sigma 2 subunit
chr11_-_46867788 1.078 CKAP5
cytoskeleton associated protein 5
chrX_+_30671456 1.067 NM_000167
NM_001128127
NM_001205019
NM_203391
GK



glycerol kinase



chr19_+_41770329 1.065 HNRNPUL1
heterogeneous nuclear ribonucleoprotein U-like 1
chr11_-_27721975 1.058 NM_001143813
NM_001143814
NM_001709
BDNF


brain-derived neurotrophic factor


chr17_+_72744802 1.058 SLC9A3R1
solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1
chr17_-_8059637 1.057 PER1
period homolog 1 (Drosophila)
chr17_+_4613780 1.052 NM_004313
NM_199004
ARRB2

arrestin, beta 2

chr17_+_26646120 1.040 NM_014573
TMEM97
transmembrane protein 97
chr2_-_131099621 1.039 NM_032357
CCDC115
coiled-coil domain containing 115
chr5_-_168727715 1.038 NM_003062
SLIT3
slit homolog 3 (Drosophila)
chr10_+_76586299 1.031 NM_012330
KAT6B
K(lysine) acetyltransferase 6B
chr19_+_41770336 1.031 HNRNPUL1
heterogeneous nuclear ribonucleoprotein U-like 1
chr19_+_1249882 1.029 MIDN
midnolin
chr1_-_145470353 1.024 NM_032305
POLR3GL
polymerase (RNA) III (DNA directed) polypeptide G (32kD)-like
chr11_-_27722446 1.023 NM_001143812
BDNF
brain-derived neurotrophic factor
chr12_+_7053180 1.020 NM_138425
C12orf57
chromosome 12 open reading frame 57
chr6_+_26045611 1.013 NM_003531
HIST1H3C
histone cluster 1, H3c
chr15_+_41625052 1.010 NUSAP1
nucleolar and spindle associated protein 1
chr20_+_42086533 1.006 SRSF6
serine/arginine-rich splicing factor 6
chr3_+_154797435 0.994 NM_000902
MME
membrane metallo-endopeptidase
chr5_+_151151516 0.992 G3BP1
GTPase activating protein (SH3 domain) binding protein 1
chr3_+_154797644 0.992 NM_007287
MME
membrane metallo-endopeptidase
chr19_+_49468656 0.984 FTL
ferritin, light polypeptide
chr2_+_23608297 0.983 NM_052920
KLHL29
kelch-like 29 (Drosophila)
chr3_+_154797910 0.980 NM_007288
MME
membrane metallo-endopeptidase
chr14_-_73360792 0.980 NM_012074
DPF3
D4, zinc and double PHD fingers, family 3
chr12_-_107380837 0.977 NM_001033050
NM_025198
MTERFD3

MTERF domain containing 3

chr14_+_24584009 0.974 DCAF11
DDB1 and CUL4 associated factor 11
chr5_+_130506656 0.971 LYRM7
Lyrm7 homolog (mouse)
chr22_-_42486766 0.966 NM_002490
NDUFA6
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 6, 14kDa
chrX_+_70503496 0.958 NONO
non-POU domain containing, octamer-binding
chr19_+_49468557 0.956 NM_000146
FTL
ferritin, light polypeptide
chr19_+_41770285 0.955 HNRNPUL1
heterogeneous nuclear ribonucleoprotein U-like 1
chr7_+_8008416 0.950 NM_138426
GLCCI1
glucocorticoid induced transcript 1
chr12_+_79258794 0.950 SYT1
synaptotagmin I
chr1_-_235491448 0.949 ARID4B
AT rich interactive domain 4B (RBP1-like)
chr11_-_63381485 0.944 PLA2G16
phospholipase A2, group XVI
chr1_-_19229016 0.944 NM_003748
NM_170726
ALDH4A1

aldehyde dehydrogenase 4 family, member A1

chr2_+_20646831 0.944 NM_004040
RHOB
ras homolog gene family, member B
chr1_+_3541550 0.944 NM_182752
TPRG1L
tumor protein p63 regulated 1-like
chr1_+_3541587 0.941 TPRG1L
tumor protein p63 regulated 1-like
chr3_+_154798078 0.941 NM_007289
MME
membrane metallo-endopeptidase
chr5_-_159546389 0.938 NM_001130864
NM_052927
PWWP2A

PWWP domain containing 2A

chr2_+_85822836 0.934 NM_016494
RNF181
ring finger protein 181
chr16_+_50775960 0.934 NM_001042355
NM_015247
CYLD

cylindromatosis (turban tumor syndrome)

chr4_+_100871625 0.931 LOC256880
uncharacterized LOC256880
chr11_-_57479510 0.927 NM_153450
MED19
mediator complex subunit 19
chr17_-_1619473 0.920 MIR22HG
MIR22 host gene (non-protein coding)
chr14_+_105941061 0.918 NM_001312
CRIP2
cysteine-rich protein 2
chr11_+_34460533 0.918 CAT
catalase
chr2_-_175712276 0.918 NM_001206602
CHN1
chimerin (chimaerin) 1
chr12_+_117176085 0.912 NM_001109903
NM_032814
RNFT2

ring finger protein, transmembrane 2

chr11_-_67120943 0.907 NM_021173
POLD4
polymerase (DNA-directed), delta 4
chr9_-_74525846 0.903 FAM108B1
family with sequence similarity 108, member B1
chr11_+_12132063 0.901 NM_014632
MICAL2
microtubule associated monoxygenase, calponin and LIM domain containing 2
chr5_+_151151511 0.901 G3BP1
GTPase activating protein (SH3 domain) binding protein 1

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
2.08 3.51e-19 GO:0007049 cell cycle
2.28 4.28e-17 GO:0022403 cell cycle phase
2.13 5.61e-16 GO:0022402 cell cycle process
2.24 4.87e-14 GO:0051276 chromosome organization
2.47 2.37e-13 GO:0000279 M phase
4.09 1.39e-12 GO:0065004 protein-DNA complex assembly
3.97 2.25e-12 GO:0071824 protein-DNA complex subunit organization
1.65 6.52e-12 GO:0006996 organelle organization
3.60 6.80e-12 GO:0006333 chromatin assembly or disassembly
2.17 1.02e-11 GO:0000278 mitotic cell cycle
4.14 5.49e-11 GO:0006334 nucleosome assembly
2.27 8.07e-11 GO:0006325 chromatin organization
1.40 2.65e-10 GO:0034641 cellular nitrogen compound metabolic process
3.93 3.71e-10 GO:0031497 chromatin assembly
3.84 3.91e-10 GO:0034728 nucleosome organization
1.43 1.01e-09 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.49 1.32e-09 GO:0090304 nucleic acid metabolic process
1.38 3.49e-09 GO:0006807 nitrogen compound metabolic process
1.23 1.55e-08 GO:0044237 cellular metabolic process
1.30 1.84e-08 GO:0044260 cellular macromolecule metabolic process
2.41 4.68e-08 GO:0000087 M phase of mitotic cell cycle
2.29 6.09e-08 GO:0010564 regulation of cell cycle process
3.00 1.03e-07 GO:0071103 DNA conformation change
2.05 1.33e-07 GO:0034621 cellular macromolecular complex subunit organization
3.16 1.55e-07 GO:0006323 DNA packaging
1.40 1.97e-07 GO:0071842 cellular component organization at cellular level
2.33 2.99e-07 GO:0051325 interphase
1.34 3.00e-07 GO:0060255 regulation of macromolecule metabolic process
2.20 4.56e-07 GO:0034622 cellular macromolecular complex assembly
1.88 5.75e-07 GO:0051726 regulation of cell cycle
2.32 9.12e-07 GO:0000280 nuclear division
2.32 9.12e-07 GO:0007067 mitosis
1.31 1.05e-06 GO:0080090 regulation of primary metabolic process
1.89 1.21e-06 GO:0006259 DNA metabolic process
2.49 2.12e-06 GO:0071156 regulation of cell cycle arrest
1.30 2.92e-06 GO:0031323 regulation of cellular metabolic process
2.26 3.01e-06 GO:0051329 interphase of mitotic cell cycle
1.31 3.24e-06 GO:0016043 cellular component organization
2.25 3.48e-06 GO:0048285 organelle fission
2.16 4.08e-06 GO:0006281 DNA repair
1.36 4.89e-06 GO:0071841 cellular component organization or biogenesis at cellular level
2.49 5.01e-06 GO:0000075 cell cycle checkpoint
2.13 5.26e-06 GO:0051301 cell division
1.69 9.92e-06 GO:0043933 macromolecular complex subunit organization
1.37 1.32e-05 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.74 3.28e-05 GO:0065003 macromolecular complex assembly
1.29 3.65e-05 GO:0071840 cellular component organization or biogenesis
1.55 3.65e-05 GO:0044248 cellular catabolic process
1.26 3.86e-05 GO:0019222 regulation of metabolic process
1.35 5.17e-05 GO:0010556 regulation of macromolecule biosynthetic process
2.74 5.65e-05 GO:0006310 DNA recombination
1.10 6.19e-05 GO:0009987 cellular process
1.22 9.27e-05 GO:0043170 macromolecule metabolic process
1.18 1.23e-04 GO:0044238 primary metabolic process
2.91 1.33e-04 GO:0007126 meiosis
2.91 1.33e-04 GO:0051327 M phase of meiotic cell cycle
1.63 1.58e-04 GO:0033554 cellular response to stress
2.88 1.66e-04 GO:0051321 meiotic cell cycle
1.82 1.80e-04 GO:0006974 response to DNA damage stimulus
1.16 1.86e-04 GO:0008152 metabolic process
1.31 2.29e-04 GO:0051171 regulation of nitrogen compound metabolic process
1.56 4.32e-04 GO:0032774 RNA biosynthetic process
1.30 7.77e-04 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.34 7.90e-04 GO:0006355 regulation of transcription, DNA-dependent
1.43 9.46e-04 GO:0009056 catabolic process
4.63 1.01e-03 GO:0006695 cholesterol biosynthetic process
1.31 1.12e-03 GO:0009058 biosynthetic process
1.33 1.23e-03 GO:0051252 regulation of RNA metabolic process
1.29 1.51e-03 GO:0009889 regulation of biosynthetic process
1.30 1.75e-03 GO:0010468 regulation of gene expression
1.38 1.94e-03 GO:0016070 RNA metabolic process
4.17 1.96e-03 GO:0016126 sterol biosynthetic process
1.55 2.16e-03 GO:0006351 transcription, DNA-dependent
2.05 2.25e-03 GO:0007346 regulation of mitotic cell cycle
1.38 2.52e-03 GO:0009059 macromolecule biosynthetic process
1.28 3.25e-03 GO:0031326 regulation of cellular biosynthetic process
1.37 3.87e-03 GO:0034645 cellular macromolecule biosynthetic process
1.30 4.52e-03 GO:0044249 cellular biosynthetic process
1.48 4.74e-03 GO:0022607 cellular component assembly
1.58 5.16e-03 GO:0071844 cellular component assembly at cellular level
8.23 5.23e-03 GO:0002566 somatic diversification of immune receptors via somatic mutation
8.23 5.23e-03 GO:0016446 somatic hypermutation of immunoglobulin genes
1.69 7.97e-03 GO:0044265 cellular macromolecule catabolic process
5.29 1.09e-02 GO:0006298 mismatch repair
1.83 1.15e-02 GO:0016568 chromatin modification
2.57 1.32e-02 GO:0000086 G2/M transition of mitotic cell cycle
2.27 1.47e-02 GO:0010498 proteasomal protein catabolic process
2.27 1.47e-02 GO:0043161 proteasomal ubiquitin-dependent protein catabolic process
4.65 1.71e-02 GO:0002200 somatic diversification of immune receptors
2.43 3.78e-02 GO:0051640 organelle localization
3.72 4.80e-02 GO:0051318 G1 phase

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.25 2.76e-47 GO:0044424 intracellular part
1.24 7.56e-47 GO:0005622 intracellular
1.50 3.87e-39 GO:0005634 nucleus
1.28 5.50e-38 GO:0043226 organelle
1.28 1.77e-37 GO:0043229 intracellular organelle
1.31 1.24e-36 GO:0043227 membrane-bounded organelle
1.31 5.72e-36 GO:0043231 intracellular membrane-bounded organelle
2.36 1.39e-16 GO:0005694 chromosome
2.43 4.89e-15 GO:0044427 chromosomal part
1.31 4.91e-15 GO:0044422 organelle part
1.21 9.98e-15 GO:0005737 cytoplasm
1.31 1.52e-14 GO:0044446 intracellular organelle part
2.90 1.52e-12 GO:0000785 chromatin
1.52 1.11e-11 GO:0044428 nuclear part
1.50 1.87e-11 GO:0070013 intracellular organelle lumen
1.49 2.69e-11 GO:0031974 membrane-enclosed lumen
1.48 1.39e-10 GO:0043233 organelle lumen
1.52 1.17e-09 GO:0031981 nuclear lumen
1.48 1.22e-09 GO:0005829 cytosol
1.34 1.46e-09 GO:0032991 macromolecular complex
1.39 7.25e-09 GO:0043228 non-membrane-bounded organelle
1.39 7.25e-09 GO:0043232 intracellular non-membrane-bounded organelle
1.57 9.89e-08 GO:0005654 nucleoplasm
1.21 1.09e-07 GO:0044444 cytoplasmic part
4.23 1.22e-07 GO:0000786 nucleosome
1.78 8.44e-07 GO:0044429 mitochondrial part
3.23 2.98e-06 GO:0032993 protein-DNA complex
2.55 6.13e-06 GO:0044454 nuclear chromosome part
1.73 6.77e-06 GO:0015630 microtubule cytoskeleton
2.32 2.00e-05 GO:0000228 nuclear chromosome
1.29 3.03e-05 GO:0043234 protein complex
1.46 7.70e-05 GO:0005739 mitochondrion
1.80 1.38e-04 GO:0005740 mitochondrial envelope
1.76 8.61e-04 GO:0031966 mitochondrial membrane
1.54 4.86e-03 GO:0031967 organelle envelope
1.04 5.01e-03 GO:0044464 cell part
1.04 5.16e-03 GO:0005623 cell
2.71 7.72e-03 GO:0000790 nuclear chromatin
2.23 9.00e-03 GO:0000775 chromosome, centromeric region
1.51 1.01e-02 GO:0031975 envelope
6.17 1.55e-02 GO:0032300 mismatch repair complex
2.21 1.57e-02 GO:0000793 condensed chromosome
2.01 2.68e-02 GO:0005819 spindle
1.47 4.00e-02 GO:0044451 nucleoplasm part

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.13 1.36e-13 GO:0005488 binding
1.52 1.06e-12 GO:0003677 DNA binding
1.41 1.30e-12 GO:0003676 nucleic acid binding
1.19 2.59e-08 GO:0005515 protein binding
1.60 3.74e-04 GO:0019899 enzyme binding
1.50 4.98e-04 GO:0030528 transcription regulator activity
1.48 1.63e-03 GO:0001071 nucleic acid binding transcription factor activity
1.48 1.63e-03 GO:0003700 sequence-specific DNA binding transcription factor activity
9.06 3.02e-03 GO:0032404 mismatch repair complex binding
6.04 7.41e-03 GO:0030983 mismatched DNA binding
1.26 1.47e-02 GO:0046914 transition metal ion binding
1.27 2.29e-02 GO:0008270 zinc ion binding
1.69 3.34e-02 GO:0003712 transcription cofactor activity
2.97 3.38e-02 GO:0003697 single-stranded DNA binding
1.68 3.62e-02 GO:0000988 protein binding transcription factor activity
1.68 3.62e-02 GO:0000989 transcription factor binding transcription factor activity