Motif ID: NHLH1,2.p2

Z-value: 1.624


Transcription factors associated with NHLH1,2.p2:

Gene SymbolEntrez IDGene Name
NHLH1 4807 nescient helix loop helix 1
NHLH2 4808 nescient helix loop helix 2

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
NHLH2chr1_-_116383323-0.902.3e-03Click!
NHLH1chr1_+_1603368560.639.7e-02Click!


Activity profile for motif NHLH1,2.p2.

activity profile for motif NHLH1,2.p2


Sorted Z-values histogram for motif NHLH1,2.p2

Sorted Z-values for motif NHLH1,2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NHLH1,2.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr7_-_137531585 2.597 NM_004717
 DGKI
diacylglycerol kinase, iota
chrX_+_16964730 2.586 NM_001080975
NM_004726
 REPS2

RALBP1 associated Eps domain containing 2

chr8_+_97506141 2.246 SDC2
syndecan 2
chr1_-_57045129 2.213 PPAP2B
phosphatidic acid phosphatase type 2B
chr8_+_97506071 2.206 SDC2
syndecan 2
chr8_+_97506020 2.117 SDC2
syndecan 2
chr8_+_97506478 2.088 SDC2
syndecan 2
chr11_+_113930430 1.992 NM_006006
 ZBTB16
zinc finger and BTB domain containing 16
chr1_+_89990396 1.922 NM_001134476
 LRRC8B
leucine rich repeat containing 8 family, member B
chr19_+_18111923 1.774 NM_001025604
 ARRDC2
arrestin domain containing 2
chr2_+_109745996 1.772 NM_001099289
 SH3RF3
SH3 domain containing ring finger 3
chr11_-_35547144 1.766 NM_001001991
NM_015430
 PAMR1

peptidase domain containing associated with muscle regeneration 1

chr2_-_230579198 1.756 NM_139072
 DNER
delta/notch-like EGF repeat containing
chr2_-_230135954 1.683 NM_001100818
NM_017933
 PID1

phosphotyrosine interaction domain containing 1

chr8_+_104383785 1.682 NM_138455
 CTHRC1
collagen triple helix repeat containing 1
chr8_+_104383701 1.638 CTHRC1
collagen triple helix repeat containing 1
chr9_-_97401588 1.614 FBP1
fructose-1,6-bisphosphatase 1
chr15_-_48937795 1.592 NM_000138
 FBN1
fibrillin 1
chr1_-_57044980 1.564 PPAP2B
phosphatidic acid phosphatase type 2B
chr1_-_57045214 1.560 PPAP2B
phosphatidic acid phosphatase type 2B

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 35 entries
enrichment   p-value GO term description
1.82 3.18e-02 GO:0010975 regulation of neuron projection development
1.58 2.66e-03 GO:0022603 regulation of anatomical structure morphogenesis
1.56 1.16e-02 GO:0040012 regulation of locomotion
1.56 3.25e-02 GO:2000145 regulation of cell motility
1.56 3.61e-02 GO:0030334 regulation of cell migration
1.53 1.30e-02 GO:0060284 regulation of cell development
1.53 1.36e-02 GO:0032870 cellular response to hormone stimulus
1.52 1.18e-02 GO:0071495 cellular response to endogenous stimulus
1.50 3.45e-02 GO:0051093 negative regulation of developmental process
1.48 2.59e-05 GO:0009725 response to hormone stimulus
1.45 6.40e-07 GO:0051128 regulation of cellular component organization
1.44 5.65e-05 GO:0009719 response to endogenous stimulus
1.43 9.50e-03 GO:0031175 neuron projection development
1.41 1.85e-02 GO:0000904 cell morphogenesis involved in differentiation
1.40 9.48e-04 GO:0045595 regulation of cell differentiation
1.38 5.67e-05 GO:0050793 regulation of developmental process
1.38 6.96e-03 GO:0007167 enzyme linked receptor protein signaling pathway
1.37 1.43e-03 GO:2000026 regulation of multicellular organismal development
1.37 3.28e-02 GO:0048666 neuron development
1.36 2.02e-04 GO:0048468 cell development

Gene overrepresentation in compartment category:

Showing 1 to 12 of 12 entries
enrichment   p-value GO term description
1.71 7.95e-03 GO:0005912 adherens junction
1.39 4.24e-02 GO:0043005 neuron projection
1.28 9.90e-03 GO:0042995 cell projection
1.27 4.56e-02 GO:0031982 vesicle
1.13 3.14e-13 GO:0005737 cytoplasm
1.12 1.65e-05 GO:0044444 cytoplasmic part
1.08 2.06e-11 GO:0044424 intracellular part
1.08 9.57e-10 GO:0005622 intracellular
1.07 2.35e-04 GO:0043226 organelle
1.07 3.12e-04 GO:0043229 intracellular organelle
1.06 1.35e-02 GO:0043227 membrane-bounded organelle
1.06 1.36e-02 GO:0043231 intracellular membrane-bounded organelle

Gene overrepresentation in function category:

Showing 1 to 2 of 2 entries
enrichment   p-value GO term description
1.12 6.00e-08 GO:0005515 protein binding
1.06 9.33e-05 GO:0005488 binding