Motif ID: NKX6-1,2.p2

Z-value: 0.303


Transcription factors associated with NKX6-1,2.p2:

Gene SymbolEntrez IDGene Name
NKX6-1 4825 NK6 homeobox 1
NKX6-2 84504 NK6 homeobox 2

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
NKX6-1chr4_-_85419386-0.472.4e-01Click!


Activity profile for motif NKX6-1,2.p2.

activity profile for motif NKX6-1,2.p2


Sorted Z-values histogram for motif NKX6-1,2.p2

Sorted Z-values for motif NKX6-1,2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NKX6-1,2.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr2_-_238322815 0.298 COL6A3
collagen, type VI, alpha 3
chr2_-_238322840 0.296 NM_004369
NM_057164
NM_057165
NM_057166
NM_057167
 COL6A3




collagen, type VI, alpha 3




chrX_+_85517970 0.277 NM_001139515
 DACH2
dachshund homolog 2 (Drosophila)
chr1_+_79086087 0.264 NM_006820
 IFI44L
interferon-induced protein 44-like
chr5_+_95066628 0.218 NM_014899
 RHOBTB3
Rho-related BTB domain containing 3
chr6_+_72922513 0.199 NM_001168407
NM_001168408
 RIMS1

regulating synaptic membrane exocytosis 1

chr14_-_60097531 0.182 NM_206852
 RTN1
reticulon 1
chr14_-_60097314 0.176 RTN1
reticulon 1
chr13_-_33760215 0.162 NM_001243466
NM_178007
 STARD13

StAR-related lipid transfer (START) domain containing 13

chr13_-_38172862 0.157 NM_001135934
NM_001135935
NM_001135936
NM_006475
 POSTN



periostin, osteoblast specific factor



chr1_+_155853546 0.152 SYT11
synaptotagmin XI
chr20_-_18477811 0.150 NM_006606
 RBBP9
retinoblastoma binding protein 9
chr14_-_61115906 0.147 NM_005982
 SIX1
SIX homeobox 1
chr4_-_138453628 0.146 NM_019035
 PCDH18
protocadherin 18
chr2_-_188419049 0.145 TFPI
tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
chr2_-_188419185 0.141 NM_001032281
NM_006287
 TFPI

tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)

chr2_+_210444364 0.137 NM_002374
NM_031845
NM_031847
 MAP2


microtubule-associated protein 2


chr10_+_31610063 0.137 NM_001128128
NM_001174094
 ZEB1

zinc finger E-box binding homeobox 1

chr6_-_46293628 0.137 NM_005822
 RCAN2
regulator of calcineurin 2
chr3_+_12392993 0.132 NM_015869
 PPARG
peroxisome proliferator-activated receptor gamma

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 7 of 7 entries
enrichment   p-value GO term description
2.89 3.72e-03 GO:0007517 muscle organ development
2.38 2.90e-02 GO:0061061 muscle structure development
1.53 2.08e-03 GO:0048513 organ development
1.43 1.00e-03 GO:0048731 system development
1.40 8.36e-04 GO:0048856 anatomical structure development
1.39 5.57e-04 GO:0007275 multicellular organismal development
1.34 2.19e-03 GO:0032502 developmental process

Nothing significant found in compartment category.

Gene overrepresentation in function category:

Showing 1 to 2 of 2 entries
enrichment   p-value GO term description
21.24 4.96e-02 GO:0004556 alpha-amylase activity
21.24 4.96e-02 GO:0016160 amylase activity