Motif ID: NR4A2.p2

Z-value: 2.320


Transcription factors associated with NR4A2.p2:

monomer

Gene SymbolEntrez IDGene Name
NR4A2 4929 nuclear receptor subfamily 4, group A, member 2

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
NR4A2chr2_-_157189040-0.611.1e-01Click!


Activity profile for motif NR4A2.p2.

activity profile for motif NR4A2.p2


Sorted Z-values histogram for motif NR4A2.p2

Sorted Z-values for motif NR4A2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NR4A2.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr15_+_43885251 6.019 NM_020990
CKMT1B
CKMT1A
creatine kinase, mitochondrial 1B
creatine kinase, mitochondrial 1A
chr12_-_52886971 4.577 NM_005554
KRT6A
keratin 6A
chr19_-_35992798 4.097 NM_001035516
DMKN
dermokine
chr1_+_46640748 4.039 NM_005727
TSPAN1
tetraspanin 1
chr20_+_58179601 3.491 NM_080672
PHACTR3
phosphatase and actin regulator 3
chr17_+_48610045 3.358 NM_017957
EPN3
epsin 3
chr16_-_68269948 3.188 NM_024939
ESRP2
epithelial splicing regulatory protein 2
chr12_-_52867521 3.066 NM_173086
KRT6C
keratin 6C
chr3_-_151034514 2.912 NM_023915
GPR87
G protein-coupled receptor 87
chr10_-_123353771 2.505 NM_001144916
FGFR2
fibroblast growth factor receptor 2
chr12_-_28124915 2.446 NM_002820
NM_198965
PTHLH

parathyroid hormone-like hormone

chr1_-_242612757 2.372 NM_001195811
NM_001195812
PLD5

phospholipase D family, member 5

chr17_+_48610077 2.312 EPN3
epsin 3
chr3_-_46718898 2.308 NM_182775
ALS2CL
ALS2 C-terminal like
chr6_-_13408368 2.250 NM_001242630
GFOD1
glucose-fructose oxidoreductase domain containing 1
chr17_-_56494889 2.162 RNF43
ring finger protein 43
chr4_-_15940362 2.040 NM_005130
FGFBP1
fibroblast growth factor binding protein 1
chr10_-_123353330 2.032 NM_001144913
NM_001144914
FGFR2

fibroblast growth factor receptor 2

chr12_-_52914080 1.972 NM_000424
KRT5
keratin 5
chr17_-_39675078 1.960 NM_002275
KRT15
keratin 15

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 9 of 9 entries
enrichment   p-value GO term description
1.60 1.18e-06 GO:0055085 transmembrane transport
1.41 1.45e-02 GO:0006811 ion transport
1.27 1.38e-02 GO:0044281 small molecule metabolic process
1.25 8.24e-03 GO:0065008 regulation of biological quality
1.21 8.97e-03 GO:0006810 transport
1.20 2.25e-03 GO:0051179 localization
1.20 2.64e-02 GO:0051234 establishment of localization
1.17 2.79e-02 GO:0023052 signaling
1.09 1.23e-05 GO:0009987 cellular process

Gene overrepresentation in compartment category:

Showing 1 to 15 of 15 entries
enrichment   p-value GO term description
2.02 6.34e-08 GO:0005743 mitochondrial inner membrane
1.92 4.89e-07 GO:0019866 organelle inner membrane
1.81 3.91e-02 GO:0016324 apical plasma membrane
1.74 5.43e-06 GO:0031966 mitochondrial membrane
1.71 7.58e-06 GO:0005740 mitochondrial envelope
1.68 4.59e-02 GO:0016323 basolateral plasma membrane
1.58 6.71e-06 GO:0044429 mitochondrial part
1.52 5.17e-05 GO:0031975 envelope
1.52 8.72e-05 GO:0031967 organelle envelope
1.45 1.71e-07 GO:0005739 mitochondrion
1.37 1.74e-02 GO:0005626 insoluble fraction
1.30 3.92e-02 GO:0000267 cell fraction
1.25 8.84e-04 GO:0044459 plasma membrane part
1.12 9.67e-03 GO:0044444 cytoplasmic part
1.08 1.79e-02 GO:0005737 cytoplasm

Gene overrepresentation in function category:

Showing 1 to 12 of 12 entries
enrichment   p-value GO term description
2.13 3.07e-02 GO:0046943 carboxylic acid transmembrane transporter activity
2.09 4.61e-02 GO:0005342 organic acid transmembrane transporter activity
2.02 5.28e-03 GO:0008509 anion transmembrane transporter activity
1.87 1.11e-02 GO:0015077 monovalent inorganic cation transmembrane transporter activity
1.76 4.59e-02 GO:0015291 secondary active transmembrane transporter activity
1.66 2.94e-03 GO:0022804 active transmembrane transporter activity
1.46 1.77e-04 GO:0022891 substrate-specific transmembrane transporter activity
1.44 1.58e-04 GO:0022857 transmembrane transporter activity
1.43 6.41e-03 GO:0015075 ion transmembrane transporter activity
1.42 2.01e-04 GO:0022892 substrate-specific transporter activity
1.34 3.18e-03 GO:0005215 transporter activity
1.10 7.83e-03 GO:0005515 protein binding