Motif ID: NR5A1,2.p2

Z-value: 0.899


Transcription factors associated with NR5A1,2.p2:

Gene SymbolEntrez IDGene Name
NR5A1 2516 nuclear receptor subfamily 5, group A, member 1
NR5A2 2494 nuclear receptor subfamily 5, group A, member 2

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
NR5A2chr1_+_199996729-0.848.9e-03Click!
NR5A1chr9_-_127269689-0.294.9e-01Click!


Activity profile for motif NR5A1,2.p2.

activity profile for motif NR5A1,2.p2


Sorted Z-values histogram for motif NR5A1,2.p2

Sorted Z-values for motif NR5A1,2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NR5A1,2.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr6_+_89790412 0.457 NM_006813
 PNRC1
proline-rich nuclear receptor coactivator 1
chr6_+_89790464 0.435 PNRC1
proline-rich nuclear receptor coactivator 1
chrX_+_103031433 0.407 NM_001128834
 PLP1
proteolipid protein 1
chr13_+_97928414 0.393 MBNL2
muscleblind-like 2 (Drosophila)
chr15_-_81616439 0.392 NM_181900
 STARD5
StAR-related lipid transfer (START) domain containing 5
chr1_-_149814264 0.391 NM_001040874
NM_003516
 HIST2H2AA4
HIST2H2AA3
histone cluster 2, H2aa4
histone cluster 2, H2aa3
chrX_+_103031797 0.387 PLP1
proteolipid protein 1
chr6_-_34360408 0.376 NUDT3
nudix (nucleoside diphosphate linked moiety X)-type motif 3
chr6_+_27775898 0.376 NM_003509
 HIST1H2AI
HIST1H2AM
HIST1H3F
histone cluster 1, H2ai
histone cluster 1, H2am
histone cluster 1, H3f
chr13_+_97928196 0.373 MBNL2
muscleblind-like 2 (Drosophila)
chr1_+_149822627 0.371 NM_001040874
NM_003516
 HIST2H2AA4
HIST2H2AA3
histone cluster 2, H2aa4
histone cluster 2, H2aa3
chr6_+_37252166 0.368 TBC1D22B
TBC1 domain family, member 22B
chr16_-_66952729 0.362 NM_001204744
NM_001204745
NM_001204746
NM_004062
 CDH16



cadherin 16, KSP-cadherin



chrX_+_103031753 0.360 NM_000533
NM_199478
 PLP1

proteolipid protein 1

chr18_+_616671 0.338 NM_199167
 CLUL1
clusterin-like 1 (retinal)
chr15_+_74218794 0.329 LOXL1
lysyl oxidase-like 1
chr15_+_74218786 0.323 NM_005576
 LOXL1
lysyl oxidase-like 1
chr14_-_103989112 0.316 CKB
creatine kinase, brain
chr6_-_43027114 0.315 NM_015950
 MRPL2
mitochondrial ribosomal protein L2
chr1_-_116383323 0.311 NM_001111061
 NHLH2
nescient helix loop helix 2

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 29 entries
enrichment   p-value GO term description
5.12 2.97e-03 GO:0015985 energy coupled proton transport, down electrochemical gradient
5.12 2.97e-03 GO:0015986 ATP synthesis coupled proton transport
4.37 1.41e-17 GO:0022904 respiratory electron transport chain
4.00 1.42e-05 GO:0042773 ATP synthesis coupled electron transport
4.00 1.42e-05 GO:0042775 mitochondrial ATP synthesis coupled electron transport
3.96 5.19e-04 GO:0006120 mitochondrial electron transport, NADH to ubiquinone
3.76 2.56e-05 GO:0006119 oxidative phosphorylation
3.71 8.69e-16 GO:0045333 cellular respiration
3.47 6.77e-14 GO:0022900 electron transport chain
3.43 3.20e-03 GO:0006096 glycolysis
2.94 1.40e-02 GO:0006007 glucose catabolic process
2.82 1.07e-04 GO:0006334 nucleosome assembly
2.68 4.23e-04 GO:0031497 chromatin assembly
2.55 1.49e-03 GO:0034728 nucleosome organization
2.53 1.16e-03 GO:0065004 protein-DNA complex assembly
2.39 4.50e-03 GO:0071824 protein-DNA complex subunit organization
2.36 3.56e-09 GO:0015980 energy derivation by oxidation of organic compounds
2.26 6.38e-12 GO:0006091 generation of precursor metabolites and energy
1.54 2.19e-04 GO:0016310 phosphorylation
1.53 1.45e-04 GO:0055114 oxidation-reduction process

Gene overrepresentation in compartment category:

Showing 1 to 20 of 28 entries
enrichment   p-value GO term description
5.59 6.09e-03 GO:0045263 proton-transporting ATP synthase complex, coupling factor F(o)
4.93 2.36e-03 GO:0005753 mitochondrial proton-transporting ATP synthase complex
4.41 8.96e-03 GO:0045259 proton-transporting ATP synthase complex
4.30 1.02e-06 GO:0005747 mitochondrial respiratory chain complex I
4.30 1.02e-06 GO:0030964 NADH dehydrogenase complex
4.30 1.02e-06 GO:0045271 respiratory chain complex I
4.19 2.29e-10 GO:0000786 nucleosome
3.94 7.94e-10 GO:0070469 respiratory chain
3.85 1.89e-08 GO:0005746 mitochondrial respiratory chain
3.49 6.11e-14 GO:0044455 mitochondrial membrane part
3.00 5.97e-07 GO:0032993 protein-DNA complex
2.53 5.89e-15 GO:0005743 mitochondrial inner membrane
2.35 7.47e-13 GO:0019866 organelle inner membrane
2.19 1.82e-13 GO:0031966 mitochondrial membrane
2.17 1.01e-13 GO:0005740 mitochondrial envelope
1.88 6.14e-12 GO:0044429 mitochondrial part
1.71 5.51e-08 GO:0031967 organelle envelope
1.70 5.04e-08 GO:0031975 envelope
1.68 2.84e-15 GO:0005739 mitochondrion
1.26 3.52e-03 GO:0005829 cytosol

Gene overrepresentation in function category:

Showing 1 to 12 of 12 entries
enrichment   p-value GO term description
4.30 4.18e-06 GO:0003954 NADH dehydrogenase activity
4.30 4.18e-06 GO:0008137 NADH dehydrogenase (ubiquinone) activity
4.30 4.18e-06 GO:0050136 NADH dehydrogenase (quinone) activity
3.70 9.34e-05 GO:0016655 oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor
2.59 3.50e-03 GO:0016651 oxidoreductase activity, acting on NADH or NADPH
2.33 1.26e-02 GO:0015078 hydrogen ion transmembrane transporter activity
1.55 1.84e-04 GO:0016491 oxidoreductase activity
1.52 6.33e-04 GO:0016773 phosphotransferase activity, alcohol group as acceptor
1.49 7.93e-04 GO:0016301 kinase activity
1.44 1.18e-03 GO:0016772 transferase activity, transferring phosphorus-containing groups
1.11 2.70e-03 GO:0005515 protein binding
1.06 2.39e-03 GO:0005488 binding