Motif ID: PATZ1.p2

Z-value: 2.205


Transcription factors associated with PATZ1.p2:

Gene SymbolEntrez IDGene Name
PATZ1 23598 POZ (BTB) and AT hook containing zinc finger 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
PATZ1chr22_-_317415650.502.1e-01Click!


Activity profile for motif PATZ1.p2.

activity profile for motif PATZ1.p2


Sorted Z-values histogram for motif PATZ1.p2

Sorted Z-values for motif PATZ1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of PATZ1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr19_-_2015628 3.277 NM_017797
 BTBD2
BTB (POZ) domain containing 2
chr10_+_111985628 2.933 NM_005962
 MXI1
MAX interactor 1
chr13_-_114018201 2.881 GRTP1
growth hormone regulated TBC protein 1
chr1_-_11714738 2.708 NM_012168
 FBXO2
F-box protein 2
chr1_-_11714471 2.481 FBXO2
F-box protein 2
chr1_-_11714396 2.376 FBXO2
F-box protein 2
chr19_-_55658310 2.285 TNNT1
troponin T type 1 (skeletal, slow)
chr14_-_21566497 1.989 ZNF219
zinc finger protein 219
chr9_+_133971862 1.844 NM_001185095
NM_001185096
NM_031426
 AIF1L


allograft inflammatory factor 1-like


chr9_+_133971902 1.805 AIF1L
allograft inflammatory factor 1-like
chr10_+_111969988 1.707 NM_001008541
 MXI1
MAX interactor 1
chr14_-_21566728 1.681 NM_016423
 ZNF219
zinc finger protein 219
chr19_-_291335 1.649 NM_003712
NM_177526
 PPAP2C

phosphatidic acid phosphatase type 2C

chr19_-_54984341 1.622 NM_145057
 CDC42EP5
CDC42 effector protein (Rho GTPase binding) 5
chr1_-_32801606 1.499 NM_023009
 MARCKSL1
MARCKS-like 1
chr18_+_11981421 1.438 NM_014214
 IMPA2
inositol(myo)-1(or 4)-monophosphatase 2
chr13_-_114018365 1.417 NM_024719
 GRTP1
growth hormone regulated TBC protein 1
chr8_-_144650998 1.394 C8orf73
chromosome 8 open reading frame 73
chr22_+_45064323 1.376 NM_001017528
NM_001017529
 PRR5

proline rich 5 (renal)

chr19_-_47734215 1.372 NM_014417
 BBC3
BCL2 binding component 3

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 125 entries
enrichment   p-value GO term description
1.93 1.34e-03 GO:0051403 stress-activated MAPK cascade
1.75 5.62e-06 GO:0031098 stress-activated protein kinase signaling cascade
1.72 1.06e-02 GO:0071901 negative regulation of protein serine/threonine kinase activity
1.71 4.88e-02 GO:0034138 toll-like receptor 3 signaling pathway
1.54 9.99e-05 GO:0016569 covalent chromatin modification
1.54 1.57e-04 GO:0016570 histone modification
1.53 5.84e-06 GO:0048011 nerve growth factor receptor signaling pathway
1.53 4.01e-02 GO:0007265 Ras protein signal transduction
1.49 3.09e-02 GO:0006184 GTP catabolic process
1.47 1.03e-05 GO:0071900 regulation of protein serine/threonine kinase activity
1.43 4.54e-07 GO:0007264 small GTPase mediated signal transduction
1.41 1.10e-05 GO:0016568 chromatin modification
1.41 1.82e-02 GO:0045786 negative regulation of cell cycle
1.40 5.37e-03 GO:0000165 MAPKKK cascade
1.40 4.75e-02 GO:0043405 regulation of MAP kinase activity
1.36 4.53e-06 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
1.36 1.02e-05 GO:0043549 regulation of kinase activity
1.35 5.05e-05 GO:0045859 regulation of protein kinase activity
1.34 2.15e-05 GO:0051338 regulation of transferase activity
1.32 1.88e-02 GO:0044419 interspecies interaction between organisms

Gene overrepresentation in compartment category:

Showing 1 to 20 of 38 entries
enrichment   p-value GO term description
1.68 6.92e-05 GO:0005925 focal adhesion
1.68 7.70e-04 GO:0030027 lamellipodium
1.63 3.70e-04 GO:0005924 cell-substrate adherens junction
1.59 1.02e-03 GO:0030055 cell-substrate junction
1.52 8.89e-05 GO:0070161 anchoring junction
1.51 5.48e-04 GO:0005912 adherens junction
1.46 8.06e-04 GO:0031252 cell leading edge
1.39 1.03e-05 GO:0048471 perinuclear region of cytoplasm
1.33 4.40e-02 GO:0016323 basolateral plasma membrane
1.24 6.37e-16 GO:0005829 cytosol
1.23 2.37e-03 GO:0015630 microtubule cytoskeleton
1.23 6.10e-03 GO:0044431 Golgi apparatus part
1.22 6.57e-11 GO:0031981 nuclear lumen
1.22 1.44e-07 GO:0005654 nucleoplasm
1.22 3.48e-05 GO:0005794 Golgi apparatus
1.21 9.36e-13 GO:0044428 nuclear part
1.21 4.95e-02 GO:0030054 cell junction
1.20 3.13e-11 GO:0043233 organelle lumen
1.20 4.82e-11 GO:0070013 intracellular organelle lumen
1.19 5.93e-11 GO:0031974 membrane-enclosed lumen

Gene overrepresentation in function category:

Showing 1 to 20 of 40 entries
enrichment   p-value GO term description
2.56 7.96e-03 GO:0070412 R-SMAD binding
1.69 2.45e-02 GO:0019902 phosphatase binding
1.54 1.20e-02 GO:0017124 SH3 domain binding
1.43 3.19e-09 GO:0019904 protein domain specific binding
1.36 1.98e-02 GO:0019787 small conjugating protein ligase activity
1.35 3.36e-02 GO:0019900 kinase binding
1.34 4.48e-03 GO:0016879 ligase activity, forming carbon-nitrogen bonds
1.34 2.15e-02 GO:0016881 acid-amino acid ligase activity
1.32 1.04e-02 GO:0016564 transcription repressor activity
1.31 5.03e-08 GO:0019899 enzyme binding
1.31 4.24e-02 GO:0008134 transcription factor binding
1.30 6.91e-03 GO:0000988 protein binding transcription factor activity
1.30 6.91e-03 GO:0000989 transcription factor binding transcription factor activity
1.30 9.07e-03 GO:0003712 transcription cofactor activity
1.28 8.15e-06 GO:0016773 phosphotransferase activity, alcohol group as acceptor
1.28 1.85e-05 GO:0043565 sequence-specific DNA binding
1.26 3.04e-07 GO:0001071 nucleic acid binding transcription factor activity
1.26 3.04e-07 GO:0003700 sequence-specific DNA binding transcription factor activity
1.26 1.01e-05 GO:0016301 kinase activity
1.26 1.73e-02 GO:0030695 GTPase regulator activity