Motif ID: PAX3,7.p2

Z-value: 0.091


Transcription factors associated with PAX3,7.p2:

Gene SymbolEntrez IDGene Name
PAX3 5077 paired box 3
PAX7 5081 paired box 7

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
PAX3chr2_-_2231633330.108.2e-01Click!
PAX7chr1_+_189574990.059.1e-01Click!


Activity profile for motif PAX3,7.p2.

activity profile for motif PAX3,7.p2


Sorted Z-values histogram for motif PAX3,7.p2

Sorted Z-values for motif PAX3,7.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of PAX3,7.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr15_-_83621350 0.046 NM_004839
NM_199330
HOMER2

homer homolog 2 (Drosophila)

chr19_+_52693328 0.040 PPP2R1A
protein phosphatase 2, regulatory subunit A, alpha
chr19_+_52693260 0.025 PPP2R1A
protein phosphatase 2, regulatory subunit A, alpha
chr12_+_7060433 0.023 NM_002831
NM_080549
PTPN6

protein tyrosine phosphatase, non-receptor type 6

chr19_+_52693334 0.015 PPP2R1A
protein phosphatase 2, regulatory subunit A, alpha
chr3_+_46411632 0.013 NM_000579
NM_001100168
CCR5

chemokine (C-C motif) receptor 5

chr19_+_52693054 0.008 NM_014225
PPP2R1A
protein phosphatase 2, regulatory subunit A, alpha
chrX_+_38420690 0.007 NM_004615
TSPAN7
tetraspanin 7
chr10_-_126432784 0.005 FAM53B
family with sequence similarity 53, member B
chr17_-_50236950 0.004 CA10
carbonic anhydrase X
chr15_-_52861177 0.004 NM_006628
ARPP19
cAMP-regulated phosphoprotein, 19kDa
chr21_+_34775189 0.003 NM_005534
IFNGR2
interferon gamma receptor 2 (interferon gamma transducer 1)
chr14_+_24584321 0.002 DCAF11
DDB1 and CUL4 associated factor 11
chr10_+_92631241 0.002 RPP30
ribonuclease P/MRP 30kDa subunit
chr3_+_14716605 0.002 NM_001184957
NM_001184958
NM_032137
C3orf20


chromosome 3 open reading frame 20


chr16_+_56598960 0.001 NM_032935
MT4
metallothionein 4

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
219.38 3.56e-03 GO:0050732 negative regulation of peptidyl-tyrosine phosphorylation
127.04 1.10e-02 GO:0060330 regulation of response to interferon-gamma
127.04 1.10e-02 GO:0060334 regulation of interferon-gamma-mediated signaling pathway

Nothing significant found in compartment category.

Gene overrepresentation in function category:

enrichment   p-value GO term description
134.10 1.52e-03 GO:0008601 protein phosphatase type 2A regulator activity
57.51 8.45e-03 GO:0019888 protein phosphatase regulator activity
49.30 1.15e-02 GO:0019208 phosphatase regulator activity