Motif ID: PAX5.p2

Z-value: 0.921


Transcription factors associated with PAX5.p2:

Gene SymbolEntrez IDGene Name
PAX5 5079 paired box 5

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
PAX5chr9_-_370343580.334.3e-01Click!


Activity profile for motif PAX5.p2.

activity profile for motif PAX5.p2


Sorted Z-values histogram for motif PAX5.p2

Sorted Z-values for motif PAX5.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of PAX5.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr15_+_101420004 0.767 NM_000693
 ALDH1A3
aldehyde dehydrogenase 1 family, member A3
chr2_-_46384 0.753 NM_001077710
 FAM110C
family with sequence similarity 110, member C
chr19_-_291168 0.731 NM_177543
 PPAP2C
phosphatidic acid phosphatase type 2C
chr1_-_1051458 0.617 C1orf159
chromosome 1 open reading frame 159
chr19_-_291335 0.554 NM_003712
NM_177526
 PPAP2C

phosphatidic acid phosphatase type 2C

chr15_+_101420032 0.549 ALDH1A3
aldehyde dehydrogenase 1 family, member A3
chr3_-_132441216 0.529 NPHP3
nephronophthisis 3 (adolescent)
chr6_-_109804322 0.512 ZBTB24
zinc finger and BTB domain containing 24
chr14_-_105634708 0.503 JAG2
jagged 2
chr22_-_20255614 0.441 NM_023004
 RTN4R
reticulon 4 receptor
chr16_-_68269948 0.440 NM_024939
 ESRP2
epithelial splicing regulatory protein 2
chr22_-_43583132 0.437 NM_015140
 TTLL12
tubulin tyrosine ligase-like family, member 12
chr1_+_117452359 0.433 NM_020440
 PTGFRN
prostaglandin F2 receptor negative regulator
chr5_-_60140041 0.431 NM_001104558
NM_024930
 ELOVL7

ELOVL fatty acid elongase 7

chr2_+_47596286 0.426 NM_002354
 EPCAM
epithelial cell adhesion molecule
chr2_+_47596447 0.413 EPCAM
epithelial cell adhesion molecule
chr16_-_17564737 0.405 NM_022166
 XYLT1
xylosyltransferase I
chr17_+_30813928 0.403 NM_003885
 CDK5R1
cyclin-dependent kinase 5, regulatory subunit 1 (p35)
chr6_-_109804432 0.391 NM_001164313
NM_014797
 ZBTB24

zinc finger and BTB domain containing 24

chr4_-_819879 0.388 NM_006651
 CPLX1
complexin 1

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 90 entries
enrichment   p-value GO term description
1.81 1.79e-02 GO:0050769 positive regulation of neurogenesis
1.79 2.82e-02 GO:0006665 sphingolipid metabolic process
1.73 4.20e-02 GO:0006643 membrane lipid metabolic process
1.72 1.41e-02 GO:0010720 positive regulation of cell development
1.70 2.44e-02 GO:0032956 regulation of actin cytoskeleton organization
1.63 2.50e-02 GO:0010769 regulation of cell morphogenesis involved in differentiation
1.63 2.93e-02 GO:0010975 regulation of neuron projection development
1.62 3.51e-02 GO:0022604 regulation of cell morphogenesis
1.59 1.35e-02 GO:0001666 response to hypoxia
1.58 2.19e-02 GO:0031344 regulation of cell projection organization
1.57 1.34e-02 GO:0051272 positive regulation of cellular component movement
1.49 3.87e-03 GO:0050767 regulation of neurogenesis
1.47 3.91e-04 GO:0060284 regulation of cell development
1.45 5.35e-03 GO:0001944 vasculature development
1.44 1.08e-03 GO:0018193 peptidyl-amino acid modification
1.44 1.64e-02 GO:0001568 blood vessel development
1.43 2.60e-02 GO:0051960 regulation of nervous system development
1.43 4.69e-02 GO:0009100 glycoprotein metabolic process
1.37 3.44e-02 GO:0016568 chromatin modification
1.34 1.65e-04 GO:0007167 enzyme linked receptor protein signaling pathway

Gene overrepresentation in compartment category:

Showing 1 to 20 of 41 entries
enrichment   p-value GO term description
1.57 6.21e-03 GO:0031965 nuclear membrane
1.52 1.40e-04 GO:0005635 nuclear envelope
1.51 2.99e-02 GO:0005912 adherens junction
1.48 3.33e-02 GO:0070161 anchoring junction
1.46 4.79e-08 GO:0000139 Golgi membrane
1.43 2.14e-08 GO:0044431 Golgi apparatus part
1.37 2.62e-02 GO:0005874 microtubule
1.35 9.19e-10 GO:0005794 Golgi apparatus
1.35 1.96e-02 GO:0005815 microtubule organizing center
1.34 8.58e-16 GO:0012505 endomembrane system
1.31 8.44e-05 GO:0015630 microtubule cytoskeleton
1.28 1.25e-03 GO:0005789 endoplasmic reticulum membrane
1.27 7.75e-04 GO:0044432 endoplasmic reticulum part
1.27 2.09e-03 GO:0042175 nuclear membrane-endoplasmic reticulum network
1.26 7.61e-04 GO:0005626 insoluble fraction
1.26 3.97e-03 GO:0031967 organelle envelope
1.26 4.27e-03 GO:0031975 envelope
1.25 6.05e-12 GO:0031090 organelle membrane
1.25 2.56e-03 GO:0005624 membrane fraction
1.24 2.14e-04 GO:0005783 endoplasmic reticulum

Gene overrepresentation in function category:

Showing 1 to 20 of 26 entries
enrichment   p-value GO term description
2.94 3.34e-02 GO:0032129 histone deacetylase activity (H3-K9 specific)
2.94 3.34e-02 GO:0046969 NAD-dependent histone deacetylase activity (H3-K9 specific)
2.21 4.67e-02 GO:0008378 galactosyltransferase activity
1.64 2.42e-04 GO:0005085 guanyl-nucleotide exchange factor activity
1.37 2.53e-02 GO:0016564 transcription repressor activity
1.36 9.82e-06 GO:0004672 protein kinase activity
1.34 4.05e-03 GO:0004674 protein serine/threonine kinase activity
1.33 8.97e-06 GO:0016773 phosphotransferase activity, alcohol group as acceptor
1.31 1.18e-02 GO:0060589 nucleoside-triphosphatase regulator activity
1.31 1.62e-02 GO:0030695 GTPase regulator activity
1.30 6.02e-05 GO:0016301 kinase activity
1.27 6.90e-05 GO:0016772 transferase activity, transferring phosphorus-containing groups
1.27 1.62e-03 GO:0019899 enzyme binding
1.25 9.77e-03 GO:0042802 identical protein binding
1.21 1.00e-05 GO:0016740 transferase activity
1.19 1.42e-06 GO:0000166 nucleotide binding
1.19 1.01e-03 GO:0030554 adenyl nucleotide binding
1.18 1.60e-04 GO:0017076 purine nucleotide binding
1.18 1.91e-04 GO:0032553 ribonucleotide binding
1.18 1.91e-04 GO:0032555 purine ribonucleotide binding