Motif ID: POU1F1.p2

Z-value: 0.660


Transcription factors associated with POU1F1.p2:

Gene SymbolEntrez IDGene Name
POU1F1 5449 POU class 1 homeobox 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
POU1F1chr3_-_87325611-0.196.5e-01Click!


Activity profile for motif POU1F1.p2.

activity profile for motif POU1F1.p2


Sorted Z-values histogram for motif POU1F1.p2

Sorted Z-values for motif POU1F1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of POU1F1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr12_-_91573264 0.917 NM_133503
DCN
decorin
chr5_-_75919051 0.870 NM_004101
F2RL2
coagulation factor II (thrombin) receptor-like 2
chr6_+_72922513 0.794 NM_001168407
NM_001168408
RIMS1

regulating synaptic membrane exocytosis 1

chr3_+_12392993 0.691 NM_015869
PPARG
peroxisome proliferator-activated receptor gamma
chrX_+_66788682 0.620 NM_001011645
AR
androgen receptor
chr6_+_72926462 0.605 NM_001168410
RIMS1
regulating synaptic membrane exocytosis 1
chr1_-_57045214 0.588 PPAP2B
phosphatidic acid phosphatase type 2B
chr3_+_148447966 0.587 NM_032049
AGTR1
angiotensin II receptor, type 1
chr11_-_102401430 0.528 NM_002423
MMP7
matrix metallopeptidase 7 (matrilysin, uterine)
chr2_+_210444364 0.455 NM_002374
NM_031845
NM_031847
MAP2


microtubule-associated protein 2


chr5_+_156696351 0.343 NM_014376
CYFIP2
cytoplasmic FMR1 interacting protein 2
chr12_-_10573041 0.336 NM_002261
NM_007333
KLRC3

killer cell lectin-like receptor subfamily C, member 3

chr1_+_114522029 0.335 NM_020190
OLFML3
olfactomedin-like 3
chr12_+_55248298 0.331 NM_058173
MUCL1
mucin-like 1
chr12_+_21679190 0.325 NM_030572
C12orf39
chromosome 12 open reading frame 39
chr12_-_91576579 0.314 DCN
decorin
chr8_-_19460005 0.313 NM_001130518
CSGALNACT1
chondroitin sulfate N-acetylgalactosaminyltransferase 1
chr2_+_109204777 0.303 LIMS1
LIM and senescent cell antigen-like domains 1
chr20_-_45061554 0.301 ELMO2
engulfment and cell motility 2
chr4_+_70894129 0.299 NM_000200
HTN3
histatin 3
chr13_-_38172862 0.293 NM_001135934
NM_001135935
NM_001135936
NM_006475
POSTN



periostin, osteoblast specific factor



chr2_+_102770401 0.289 NM_000877
IL1R1
interleukin 1 receptor, type I
chr1_-_57045235 0.286 NM_003713
PPAP2B
phosphatidic acid phosphatase type 2B
chr3_-_121379757 0.284 NM_005335
HCLS1
hematopoietic cell-specific Lyn substrate 1
chr4_-_100242487 0.276 NM_000668
ADH1A
ADH1B
alcohol dehydrogenase 1A (class I), alpha polypeptide
alcohol dehydrogenase 1B (class I), beta polypeptide
chr4_+_74347461 0.254 NM_001133
AFM
afamin
chr3_-_121379701 0.253 HCLS1
hematopoietic cell-specific Lyn substrate 1
chr10_-_21186530 0.250 NM_006393
NEBL
nebulette
chr1_-_163172863 0.237 NM_003617
RGS5
regulator of G-protein signaling 5
chr5_+_92918924 0.227 NM_005654
NR2F1
nuclear receptor subfamily 2, group F, member 1
chr8_-_82395401 0.223 NM_001442
FABP4
fatty acid binding protein 4, adipocyte
chr2_+_24807345 0.216 NM_003743
NM_147223
NM_147233
NCOA1


nuclear receptor coactivator 1


chr14_-_73453651 0.214 NM_178441
ZFYVE1
zinc finger, FYVE domain containing 1
chr14_-_101036130 0.213 NM_020836
BEGAIN
brain-enriched guanylate kinase-associated homolog (rat)
chr18_+_6834431 0.210 NM_001010000
ARHGAP28
Rho GTPase activating protein 28
chr19_-_44384240 0.209 NM_001033719
ZNF404
zinc finger protein 404
chr18_-_3011944 0.208 NM_014646
LPIN2
lipin 2
chr15_-_99789585 0.208 NM_001040655
NM_001040656
NM_001040657
NM_001040658
NM_001040659
NM_001040660
NM_022905
TTC23






tetratricopeptide repeat domain 23






chr2_-_88427535 0.206 NM_001443
FABP1
fatty acid binding protein 1, liver
chr9_-_16727887 0.204 BNC2
basonuclin 2
chr4_+_71108304 0.202 NM_005212
CSN3
casein kappa
chr9_-_123812535 0.202 NM_001735
C5
complement component 5
chr20_+_123230 0.193 NM_030931
DEFB126
defensin, beta 126
chr3_+_51895644 0.188 NM_203424
IQCF2
IQ motif containing F2
chr2_-_224467142 0.182 NM_003469
SCG2
secretogranin II
chr1_+_145096391 0.180 NM_004892
SEC22B
SEC22 vesicle trafficking protein homolog B (S. cerevisiae) (gene/pseudogene)
chr12_-_10588543 0.180 NM_002260
KLRC2
KLRC3
killer cell lectin-like receptor subfamily C, member 2
killer cell lectin-like receptor subfamily C, member 3
chr10_+_104613966 0.177 NM_001136200
NM_144591
C10orf32-AS3MT
C10orf32

C10orf32-AS3MT readthrough
chromosome 10 open reading frame 32

chr14_-_20774089 0.176 TTC5
tetratricopeptide repeat domain 5
chr15_-_31947541 0.175 NM_130901
OTUD7A
OTU domain containing 7A
chr15_-_89089792 0.174 NM_001144074
NM_017996
DET1

de-etiolated homolog 1 (Arabidopsis)

chr6_+_73076431 0.171 NM_001168411
RIMS1
regulating synaptic membrane exocytosis 1
chr3_-_49851217 0.170 UBA7
ubiquitin-like modifier activating enzyme 7
chr14_-_20774129 0.169 NM_138376
TTC5
tetratricopeptide repeat domain 5
chr3_-_100712248 0.166 NM_015429
ABI3BP
ABI family, member 3 (NESH) binding protein
chr5_-_39394423 0.165 DAB2
disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)
chr2_+_210444154 0.165 MAP2
microtubule-associated protein 2
chr19_-_48752921 0.164 NM_001184901
NM_001184903
NM_014959
CARD8


caspase recruitment domain family, member 8


chr6_-_117747017 0.164 NM_002944
ROS1
c-ros oncogene 1 , receptor tyrosine kinase
chr1_+_171060017 0.163 NM_001002294
NM_006894
FMO3

flavin containing monooxygenase 3

chr1_-_89591685 0.160 NM_004120
GBP2
guanylate binding protein 2, interferon-inducible
chr4_+_141264596 0.160 NM_001153446
NM_001153635
NM_001153585
NM_001153690
SCOC



short coiled-coil protein



chr10_+_69869249 0.158 NM_032578
MYPN
myopalladin
chr8_-_108510094 0.158 NM_001146
NM_001199859
ANGPT1

angiopoietin 1

chr1_+_196946666 0.156 NM_030787
CFHR5
complement factor H-related 5
chr2_+_109204745 0.156 NM_004987
LIMS1
LIM and senescent cell antigen-like domains 1
chr13_+_46276445 0.155 NM_152719
SPERT
spermatid associated
chr6_-_33041266 0.155 NM_033554
HLA-DPA1
major histocompatibility complex, class II, DP alpha 1
chr2_+_152214105 0.155 NM_007115
TNFAIP6
tumor necrosis factor, alpha-induced protein 6
chr5_+_54320083 0.154 NM_002104
GZMK
granzyme K (granzyme 3; tryptase II)
chr3_+_113616317 0.153 NM_001172105
GRAMD1C
GRAM domain containing 1C
chr10_+_111765725 0.153 NM_019903
ADD3
adducin 3 (gamma)
chr1_+_196788860 0.151 NM_002113
CFHR1
complement factor H-related 1
chr2_+_109204904 0.147 NM_001193488
LIMS1
LIM and senescent cell antigen-like domains 1
chr3_-_138478184 0.146 NM_006219
PIK3CB
phosphoinositide-3-kinase, catalytic, beta polypeptide
chr3_-_164796275 0.145 NM_001041
SI
sucrase-isomaltase (alpha-glucosidase)
chr17_-_67138013 0.144 NM_080284
ABCA6
ATP-binding cassette, sub-family A (ABC1), member 6
chr2_-_171923482 0.144 NM_001136555
TLK1
tousled-like kinase 1
chr5_+_140602914 0.143 NM_018934
PCDHB14
protocadherin beta 14
chr16_+_55515468 0.140 NM_001127891
MMP2
matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
chrX_-_57164057 0.139 NM_019003
SPIN2A
spindlin family, member 2A
chrX_-_19988381 0.139 NM_198279
CXorf23
chromosome X open reading frame 23
chr6_+_46761093 0.136 NM_005588
MEP1A
meprin A, alpha (PABA peptide hydrolase)
chr13_-_49110117 0.134 RCBTB2
regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
chr15_-_93632161 0.132 NM_020211
RGMA
RGM domain family, member A
chr1_+_160336856 0.132 NM_005598
NHLH1
nescient helix loop helix 1
chr10_+_89117424 0.132 NM_001009610
FAM22A
FAM22D
family with sequence similarity 22, member A
family with sequence similarity 22, member D
chr5_-_147286064 0.130 NM_206966
C5orf46
chromosome 5 open reading frame 46
chr8_+_27182995 0.129 NM_173176
PTK2B
PTK2B protein tyrosine kinase 2 beta
chr3_-_195310985 0.129 NM_001647
APOD
apolipoprotein D
chr2_-_224467095 0.128 SCG2
secretogranin II
chr17_-_38978824 0.126 NM_000421
KRT10
keratin 10
chr1_-_1711453 0.125 NM_001198994
NADK
NAD kinase
chr17_+_3377346 0.125 NM_001128085
ASPA
aspartoacylase
chr4_-_186697065 0.125 NM_001145673
SORBS2
sorbin and SH3 domain containing 2
chrX_+_135278912 0.124 NM_001159701
NM_001159699
FHL1

four and a half LIM domains 1

chr2_+_79347487 0.124 NM_002909
REG1A
regenerating islet-derived 1 alpha
chr15_+_25101697 0.124 NM_022805
SNRPN
small nuclear ribonucleoprotein polypeptide N
chr9_-_95244634 0.121 ASPN
asporin
chr9_+_79074067 0.119 NM_001097633
NM_001490
GCNT1

glucosaminyl (N-acetyl) transferase 1, core 2

chrX_+_22050920 0.119 NM_000444
PHEX
phosphate regulating endopeptidase homolog, X-linked
chr12_+_72332625 0.118 NM_173353
TPH2
tryptophan hydroxylase 2
chrX_-_8139307 0.118 NM_016378
VCX2
variable charge, X-linked 2
chr17_-_39222126 0.116 NM_033184
KRTAP2-4
keratin associated protein 2-4
chr6_+_16143281 0.115 MYLIP
myosin regulatory light chain interacting protein
chr2_+_79347610 0.115 REG1A
regenerating islet-derived 1 alpha
chr5_+_137203559 0.114 MYOT
myotilin
chr17_+_33448597 0.113 NM_017559
FNDC8
fibronectin type III domain containing 8
chr3_+_46395224 0.112 NM_001123041
NM_001123396
CCR2

chemokine (C-C motif) receptor 2

chr3_-_151102536 0.112 NM_022788
P2RY12
purinergic receptor P2Y, G-protein coupled, 12
chr3_-_169587598 0.111 NM_024727
LRRC31
leucine rich repeat containing 31
chr10_+_124670216 0.111 NM_001029888
FAM24A
family with sequence similarity 24, member A
chr4_-_156787377 0.110 NM_017419
ACCN5
amiloride-sensitive cation channel 5, intestinal
chrX_-_99987072 0.109 NM_001129896
SYTL4
synaptotagmin-like 4
chr1_+_101185195 0.108 NM_001078
NM_001199834
NM_080682
VCAM1


vascular cell adhesion molecule 1


chr2_-_79315118 0.106 NM_006507
REG1B
regenerating islet-derived 1 beta
chr7_-_14880954 0.105 NM_004080
NM_145695
DGKB

diacylglycerol kinase, beta 90kDa

chr1_-_201465700 0.104 NM_001193572
CSRP1
cysteine and glycine-rich protein 1
chr6_+_20534686 0.103 NM_017774
CDKAL1
CDK5 regulatory subunit associated protein 1-like 1
chr11_-_18956545 0.101 NM_147199
MRGPRX1
MAS-related GPR, member X1
chr3_-_114790221 0.101 NM_001164343
ZBTB20
zinc finger and BTB domain containing 20
chr1_-_93399531 0.101


chr17_+_78356710 0.100 RNF213
ring finger protein 213
chr2_-_175712276 0.100 NM_001206602
CHN1
chimerin (chimaerin) 1
chr8_-_42623928 0.099 NM_001199279
NM_004198
CHRNA6

cholinergic receptor, nicotinic, alpha 6

chr3_+_112051914 0.099 NM_001004196
NM_005944
CD200

CD200 molecule

chr12_-_50790391 0.097 NM_001145475
FAM186A
family with sequence similarity 186, member A
chr10_+_88985204 0.097 NM_001099338
FAM22A
FAM22D
family with sequence similarity 22, member A
family with sequence similarity 22, member D
chr4_-_170679027 0.096 NM_017867
C4orf27
chromosome 4 open reading frame 27
chr20_+_31870940 0.096 NM_033197
BPIFB1
BPI fold containing family B, member 1
chr13_+_49684388 0.095 NM_014923
FNDC3A
fibronectin type III domain containing 3A
chr2_+_36923832 0.094 NM_001177969
NM_001177970
NM_001177971
NM_001177972
NM_053276
VIT




vitrin




chr9_+_96846710 0.093 NM_001253829
NM_152422
PTPDC1

protein tyrosine phosphatase domain containing 1

chr8_+_27183047 0.092 PTK2B
PTK2B protein tyrosine kinase 2 beta
chr17_+_18647325 0.092 NM_031456
FBXW10
F-box and WD repeat domain containing 10
chr17_+_3379295 0.092 NM_000049
ASPA
aspartoacylase
chr6_+_72926144 0.089 NM_001168409
RIMS1
regulating synaptic membrane exocytosis 1
chrX_+_154255063 0.089 NM_023934
FUNDC2
FUN14 domain containing 2
chr9_-_21077804 0.089 NM_002176
IFNB1
interferon, beta 1, fibroblast
chr1_+_196912910 0.089 NM_005666
CFHR2
complement factor H-related 2
chrX_+_108779009 0.088 NM_018698
NXT2
nuclear transport factor 2-like export factor 2
chr11_+_59807747 0.088 NM_173801
PLAC1L
placenta-specific 1-like
chr3_-_160101443 0.087 NM_001190242
IFT80
intraflagellar transport 80 homolog (Chlamydomonas)
chr4_-_140060601 0.086 NM_201999
ELF2
E74-like factor 2 (ets domain transcription factor)
chr18_-_40695483 0.085 NM_002930
RIT2
Ras-like without CAAX 2
chrX_+_107683015 0.085 NM_000495
NM_033380
COL4A5

collagen, type IV, alpha 5

chr1_+_162602308 0.085 DDR2
discoidin domain receptor tyrosine kinase 2
chr5_+_141346401 0.085 NM_001201365
NM_183399
RNF14

ring finger protein 14

chr18_+_54424444 0.084 WDR7
WD repeat domain 7
chr5_-_58295758 0.084 NM_001197223
PDE4D
phosphodiesterase 4D, cAMP-specific
chr4_-_159092509 0.084 FAM198B
family with sequence similarity 198, member B
chr4_+_71263598 0.084 NM_021225
PROL1
proline rich, lacrimal 1
chr14_+_60712469 0.083 NM_177952
PPM1A
protein phosphatase, Mg2+/Mn2+ dependent, 1A
chr20_+_2276612 0.082 NM_003245
TGM3
transglutaminase 3 (E polypeptide, protein-glutamine-gamma-glutamyltransferase)
chr17_-_29641068 0.082 EVI2B
ecotropic viral integration site 2B
chr12_+_60083125 0.082 NM_004731
SLC16A7
solute carrier family 16, member 7 (monocarboxylic acid transporter 2)
chr3_+_180320955 0.081 TTC14
tetratricopeptide repeat domain 14
chr9_-_21187529 0.081 NM_021068
IFNA4
interferon, alpha 4
chr12_+_8325149 0.080 NM_001004328
ZNF705A
zinc finger protein 705A
chr7_+_149570004 0.079 NM_001100592
NM_145230
ATP6V0E2

ATPase, H+ transporting V0 subunit e2

chr8_-_7220489 0.077 NM_001164457
ZNF705G
zinc finger protein 705G
chr6_+_28109611 0.076 NM_006298
ZNF192
zinc finger protein 192
chr1_+_162466963 0.076 NM_001184763
UHMK1
U2AF homology motif (UHM) kinase 1
chr2_-_122159140 0.075 CLASP1
cytoplasmic linker associated protein 1
chr5_-_59783885 0.075 NM_001165899
PDE4D
phosphodiesterase 4D, cAMP-specific
chr18_-_52625278 0.075 NM_001143829
CCDC68
coiled-coil domain containing 68
chr17_-_39165343 0.075 NM_031958
KRTAP3-1
keratin associated protein 3-1
chrX_-_49460568 0.073 NM_003785
PAGE1
P antigen family, member 1 (prostate associated)
chr4_-_118006731 0.073 NM_152402
TRAM1L1
translocation associated membrane protein 1-like 1
chr7_+_29519485 0.072 NM_001039936
CHN2
chimerin (chimaerin) 2
chr18_-_29340698 0.072 NM_001034172
MCART2
mitochondrial carrier triple repeat 2
chr10_-_50342052 0.070 NM_001164484
FAM170B
family with sequence similarity 170, member B
chr11_-_40315663 0.069 NM_020929
LRRC4C
leucine rich repeat containing 4C
chr4_-_70080448 0.068 NM_001073
UGT2B11
UGT2B10
UDP glucuronosyltransferase 2 family, polypeptide B11
UDP glucuronosyltransferase 2 family, polypeptide B10
chr6_+_47749774 0.068 NM_181744
OPN5
opsin 5
chr5_+_140743755 0.068 NM_018918
NM_032054
PCDHGA5

protocadherin gamma subfamily A, 5

chr5_+_71502700 0.068 MAP1B
microtubule-associated protein 1B
chr5_+_140729723 0.068 NM_018922
NM_032095
PCDHGB1

protocadherin gamma subfamily B, 1

chr1_-_101360405 0.067 NM_001033025
NM_001439
EXTL2

exostoses (multiple)-like 2

chr11_+_67376926 0.067 NDUFV1
NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa
chr5_+_137673223 0.067 NM_001135647
FAM53C
family with sequence similarity 53, member C
chr4_-_104020964 0.067 NM_020139
BDH2
3-hydroxybutyrate dehydrogenase, type 2
chr6_-_52628272 0.066 NM_000846
GSTA2
glutathione S-transferase alpha 2
chr2_+_54342409 0.065 NM_138448
ACYP2
acylphosphatase 2, muscle type
chr2_-_128439359 0.065 NM_001161404
LIMS2
LIM and senescent cell antigen-like domains 2
chr10_+_15085894 0.065 NM_001039702
NM_018324
OLAH

oleoyl-ACP hydrolase

chr4_+_100495972 0.065 MTTP
microsomal triglyceride transfer protein
chr1_-_153283166 0.065 NM_052891
PGLYRP3
peptidoglycan recognition protein 3
chr20_+_56964162 0.064 NM_001195677
NM_004738
VAPB

VAMP (vesicle-associated membrane protein)-associated protein B and C

chr20_+_57470200 0.064 GNAS
GNAS complex locus
chr6_-_41168923 0.063 NM_024807
TREML2
triggering receptor expressed on myeloid cells-like 2
chr9_-_19378815 0.063 RPS6
ribosomal protein S6
chr4_+_88742549 0.063 NM_001184694
MEPE
matrix extracellular phosphoglycoprotein
chr5_+_57787260 0.062 NM_152687
GAPT
GRB2-binding adaptor protein, transmembrane
chr5_+_59784004 0.062 PART1
prostate androgen-regulated transcript 1 (non-protein coding)
chrX_-_102774416 0.062 NM_080879
RAB40A
RAB40A, member RAS oncogene family
chr20_+_138121 0.062 NM_139074
DEFB127
defensin, beta 127
chr9_-_91793681 0.061 NM_016848
SHC3
SHC (Src homology 2 domain containing) transforming protein 3
chr2_+_233498206 0.061 NM_025202
EFHD1
EF-hand domain family, member D1
chr12_+_7167979 0.060 NM_001734
NM_201442
C1S

complement component 1, s subcomponent


Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
2.69 1.49e-05 GO:0050776 regulation of immune response
2.16 3.59e-05 GO:0006952 defense response
1.89 5.70e-05 GO:0002376 immune system process
2.18 7.54e-05 GO:0006955 immune response
2.68 3.09e-04 GO:0045087 innate immune response
2.69 5.14e-03 GO:0050778 positive regulation of immune response
2.32 6.04e-03 GO:0002684 positive regulation of immune system process
2.01 7.09e-03 GO:0002682 regulation of immune system process
1.56 1.02e-02 GO:0048583 regulation of response to stimulus
2.79 2.36e-02 GO:0002253 activation of immune response
1.85 3.35e-02 GO:0048584 positive regulation of response to stimulus

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.47 7.63e-03 GO:0005576 extracellular region
9.64 2.66e-02 GO:0042613 MHC class II protein complex

Nothing significant found in function category.