Motif ID: POU2F1..3.p2

Z-value: 1.120


Transcription factors associated with POU2F1..3.p2:

Gene SymbolEntrez IDGene Name
POU2F1 5451 POU class 2 homeobox 1
POU2F2 5452 POU class 2 homeobox 2
POU2F3 25833 POU class 2 homeobox 3

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
POU2F1chr1_+_1672983820.902.2e-03Click!
POU2F2chr19_-_426365590.782.2e-02Click!
POU2F3chr11_+_120107348,
chr11_+_120110902		-0.413.2e-01Click!


Activity profile for motif POU2F1..3.p2.

activity profile for motif POU2F1..3.p2


Sorted Z-values histogram for motif POU2F1..3.p2

Sorted Z-values for motif POU2F1..3.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of POU2F1..3.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr6_-_11779279 2.139 NM_001143948
NM_032744
 C6orf105

chromosome 6 open reading frame 105

chrX_-_24665454 1.499 NM_001163265
NM_004845
 PCYT1B

phosphate cytidylyltransferase 1, choline, beta

chr5_+_36608430 1.445 NM_001166695
 SLC1A3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr18_-_53089722 1.252 NM_001243233
 TCF4
transcription factor 4
chrX_-_24665225 1.152 PCYT1B
phosphate cytidylyltransferase 1, choline, beta
chr10_-_98031154 1.132 NM_001114094
NM_013314
 BLNK

B-cell linker

chr6_+_26124372 1.099 NM_003512
 HIST1H2AC
histone cluster 1, H2ac
chr10_-_123356158 1.081 NM_001144915
 FGFR2
fibroblast growth factor receptor 2
chr17_-_56494889 1.059 RNF43
ring finger protein 43
chr9_-_140196702 1.042 NM_001004354
 NRARP
NOTCH-regulated ankyrin repeat protein
chr1_+_206730456 1.015 NM_182665
 RASSF5
Ras association (RalGDS/AF-6) domain family member 5
chr12_-_31479120 1.014 NM_001135811
NM_021238
NM_001135812
 FAM60A


family with sequence similarity 60, member A


chr12_-_31479084 0.994 FAM60A
family with sequence similarity 60, member A
chr12_+_107712151 0.976 NM_001018072
 BTBD11
BTB (POZ) domain containing 11
chrX_-_117119282 0.961 NM_001168299
 KLHL13
kelch-like 13 (Drosophila)
chr12_-_31479038 0.950 FAM60A
family with sequence similarity 60, member A
chr9_-_117160748 0.944 AKNA
AT-hook transcription factor
chr20_+_62795773 0.943 MYT1
myelin transcription factor 1
chr6_+_27215479 0.927 NM_005865
 PRSS16
protease, serine, 16 (thymus)
chr17_-_56494930 0.911 NM_017763
 RNF43
ring finger protein 43

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 22 entries
enrichment   p-value GO term description
12.46 8.11e-03 GO:0050853 B cell receptor signaling pathway
8.58 1.69e-10 GO:0006334 nucleosome assembly
8.14 4.90e-10 GO:0031497 chromatin assembly
8.13 1.28e-10 GO:0034728 nucleosome organization
7.45 2.84e-09 GO:0065004 protein-DNA complex assembly
7.40 8.94e-10 GO:0071824 protein-DNA complex subunit organization
7.34 1.62e-02 GO:0050909 sensory perception of taste
6.43 4.83e-09 GO:0006333 chromatin assembly or disassembly
6.22 9.09e-08 GO:0006323 DNA packaging
5.87 3.19e-08 GO:0071103 DNA conformation change
4.67 3.46e-02 GO:0050851 antigen receptor-mediated signaling pathway
3.16 2.01e-04 GO:0034622 cellular macromolecular complex assembly
2.85 2.41e-04 GO:0006325 chromatin organization
2.81 2.07e-04 GO:0034621 cellular macromolecular complex subunit organization
2.49 4.63e-05 GO:0006955 immune response
2.34 8.38e-03 GO:0051276 chromosome organization
2.16 1.31e-02 GO:0071844 cellular component assembly at cellular level
2.13 2.76e-05 GO:0002376 immune system process
2.08 1.73e-02 GO:0006952 defense response
1.68 9.32e-03 GO:0048513 organ development

Gene overrepresentation in compartment category:

Showing 1 to 7 of 7 entries
enrichment   p-value GO term description
12.50 5.03e-14 GO:0000786 nucleosome
7.89 4.93e-10 GO:0032993 protein-DNA complex
4.29 1.91e-07 GO:0000785 chromatin
2.43 4.41e-03 GO:0044427 chromosomal part
2.34 2.31e-03 GO:0005694 chromosome
1.45 2.01e-02 GO:0043228 non-membrane-bounded organelle
1.45 2.01e-02 GO:0043232 intracellular non-membrane-bounded organelle

Gene overrepresentation in function category:

Showing 1 to 3 of 3 entries
enrichment   p-value GO term description
8.88 1.57e-04 GO:0003823 antigen binding
2.64 1.52e-02 GO:0003779 actin binding
2.15 3.62e-02 GO:0008092 cytoskeletal protein binding