Motif ID: POU5F1.p2

Z-value: 0.989


Transcription factors associated with POU5F1.p2:

Gene SymbolEntrez IDGene Name
POU5F1 5460 POU class 5 homeobox 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
POU5F1chr6_-_311346140.762.7e-02Click!


Activity profile for motif POU5F1.p2.

activity profile for motif POU5F1.p2


Sorted Z-values histogram for motif POU5F1.p2

Sorted Z-values for motif POU5F1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of POU5F1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chrX_-_33357725 0.989 NM_000109
 DMD
dystrophin
chr1_-_23885916 0.876 ID3
inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
chr10_-_98031154 0.876 NM_001114094
NM_013314
 BLNK

B-cell linker

chr17_+_67410825 0.869 NM_002758
 MAP2K6
mitogen-activated protein kinase kinase 6
chr6_+_26124372 0.818 NM_003512
 HIST1H2AC
histone cluster 1, H2ac
chr2_+_233734993 0.744 NM_206895
 C2orf82
chromosome 2 open reading frame 82
chr1_+_27668462 0.733 NM_001193308
NM_032872
 SYTL1

synaptotagmin-like 1

chr1_+_27668499 0.730 SYTL1
synaptotagmin-like 1
chr16_-_48269087 0.711 NM_032583
NM_145186
 ABCC11

ATP-binding cassette, sub-family C (CFTR/MRP), member 11

chr1_-_108231122 0.694 NM_001079874
 VAV3
vav 3 guanine nucleotide exchange factor
chr18_-_53089722 0.657 NM_001243233
 TCF4
transcription factor 4
chr19_-_44124013 0.653 NM_182498
 ZNF428
zinc finger protein 428
chr10_-_116286661 0.626 NM_006720
 ABLIM1
actin binding LIM protein 1
chr1_+_15272414 0.618 NM_001017999
 KAZN
kazrin, periplakin interacting protein
chr7_+_129008044 0.559 AHCYL2
adenosylhomocysteinase-like 2
chrX_+_80457559 0.553 SH3BGRL
SH3 domain binding glutamic acid-rich protein like
chr19_+_6135650 0.547 NM_030924
 ACSBG2
acyl-CoA synthetase bubblegum family member 2
chrX_-_31526414 0.546 NM_004014
 DMD
dystrophin
chr13_+_97874704 0.494 MBNL2
muscleblind-like 2 (Drosophila)
chr19_-_44123732 0.482 ZNF428
zinc finger protein 428

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 97 entries
enrichment   p-value GO term description
3.90 7.53e-03 GO:0048663 neuron fate commitment
3.23 1.45e-04 GO:0006334 nucleosome assembly
3.18 2.03e-03 GO:0048706 embryonic skeletal system development
3.07 4.67e-04 GO:0031497 chromatin assembly
3.03 3.59e-04 GO:0034728 nucleosome organization
2.81 3.05e-03 GO:0065004 protein-DNA complex assembly
2.80 1.23e-04 GO:0006333 chromatin assembly or disassembly
2.76 2.75e-03 GO:0071824 protein-DNA complex subunit organization
2.67 1.05e-04 GO:0009952 anterior/posterior pattern formation
2.59 9.64e-03 GO:0033673 negative regulation of kinase activity
2.53 3.52e-02 GO:0006469 negative regulation of protein kinase activity
2.52 1.16e-02 GO:0006323 DNA packaging
2.45 3.00e-02 GO:0051348 negative regulation of transferase activity
2.40 1.13e-02 GO:0071103 DNA conformation change
2.30 3.66e-02 GO:0048562 embryonic organ morphogenesis
2.27 6.07e-04 GO:0003002 regionalization
2.22 1.17e-03 GO:0030097 hemopoiesis
2.14 7.28e-03 GO:0048568 embryonic organ development
2.11 2.40e-02 GO:0045786 negative regulation of cell cycle
2.07 4.75e-03 GO:0048534 hemopoietic or lymphoid organ development

Gene overrepresentation in compartment category:

Showing 1 to 7 of 7 entries
enrichment   p-value GO term description
11.43 2.35e-02 GO:0070382 exocytic vesicle
4.00 6.05e-06 GO:0000786 nucleosome
2.77 2.16e-03 GO:0032993 protein-DNA complex
2.24 8.84e-05 GO:0000785 chromatin
1.25 3.48e-08 GO:0005634 nucleus
1.09 2.00e-04 GO:0005622 intracellular
1.09 4.58e-04 GO:0044424 intracellular part

Gene overrepresentation in function category:

Showing 1 to 10 of 10 entries
enrichment   p-value GO term description
2.21 9.10e-15 GO:0043565 sequence-specific DNA binding
2.03 1.45e-16 GO:0001071 nucleic acid binding transcription factor activity
2.03 1.45e-16 GO:0003700 sequence-specific DNA binding transcription factor activity
1.92 1.13e-13 GO:0030528 transcription regulator activity
1.91 4.43e-03 GO:0016564 transcription repressor activity
1.86 9.29e-03 GO:0016563 transcription activator activity
1.43 1.12e-07 GO:0003677 DNA binding
1.27 2.26e-04 GO:0003676 nucleic acid binding
1.21 9.01e-10 GO:0005515 protein binding
1.12 6.49e-10 GO:0005488 binding