Motif ID: POU6F1.p2

Z-value: 0.576


Transcription factors associated with POU6F1.p2:

Gene SymbolEntrez IDGene Name
POU6F1 5463 POU class 6 homeobox 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
POU6F1chr12_-_516114760.373.7e-01Click!


Activity profile for motif POU6F1.p2.

activity profile for motif POU6F1.p2


Sorted Z-values histogram for motif POU6F1.p2

Sorted Z-values for motif POU6F1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of POU6F1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_+_153003677 0.811 NM_003125
SPRR1B
small proline-rich protein 1B
chr20_+_62795773 0.681 MYT1
myelin transcription factor 1
chr18_+_47088400 0.539 NM_006033
LIPG
lipase, endothelial
chr7_-_83824216 0.459 NM_006080
SEMA3A
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chrX_+_65382432 0.399 NM_138737
HEPH
hephaestin
chr5_+_140220811 0.366 NM_018911
NM_031856
PCDHA8

protocadherin alpha 8

chr12_-_28124915 0.356 NM_002820
NM_198965
PTHLH

parathyroid hormone-like hormone

chr1_-_116311330 0.320 CASQ2
calsequestrin 2 (cardiac muscle)
chr6_-_136847078 0.314 NM_001198608
NM_001198609
NM_001198611
MAP7


microtubule-associated protein 7


chr1_-_116311161 0.310 CASQ2
calsequestrin 2 (cardiac muscle)
chr1_-_116311398 0.304 NM_001232
CASQ2
calsequestrin 2 (cardiac muscle)
chr3_-_111314181 0.288 NM_024508
ZBED2
zinc finger, BED-type containing 2
chr10_+_99498233 0.273 NM_001002261
ZFYVE27
zinc finger, FYVE domain containing 27
chr3_-_112564789 0.267 NM_001008784
NM_001199215
CD200R1L

CD200 receptor 1-like

chr19_-_33360641 0.264 NM_001126335
NM_001243036
NM_014270
SLC7A9


solute carrier family 7 (glycoprotein-associated amino acid transporter light chain, bo,+ system), member 9


chr9_-_95166827 0.263 NM_014057
NM_033014
OGN

osteoglycin

chr17_-_56492938 0.237 RNF43
ring finger protein 43
chr1_+_15272414 0.234 NM_001017999
KAZN
kazrin, periplakin interacting protein
chr3_+_127641901 0.225 NM_207335
KBTBD12
kelch repeat and BTB (POZ) domain containing 12
chr1_+_186798031 0.225 NM_024420
PLA2G4A
phospholipase A2, group IVA (cytosolic, calcium-dependent)
chr4_+_40198526 0.216 NM_004310
RHOH
ras homolog gene family, member H
chr10_+_5005685 0.204 AKR1C1
aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase)
chr7_-_107880492 0.203 NM_001037132
NRCAM
neuronal cell adhesion molecule
chr11_-_16497917 0.203 NM_033326
SOX6
SRY (sex determining region Y)-box 6
chr6_-_138189313 0.192


chrX_-_117119282 0.186 NM_001168299
KLHL13
kelch-like 13 (Drosophila)
chr12_+_105153258 0.181 CHST11
carbohydrate (chondroitin 4) sulfotransferase 11
chrX_-_33229428 0.167 NM_004006
DMD
dystrophin
chr12_-_51611476 0.165 POU6F1
POU class 6 homeobox 1
chr6_-_47254143 0.161 TNFRSF21
tumor necrosis factor receptor superfamily, member 21
chr1_-_93342706 0.154 NM_001252271
FAM69A
family with sequence similarity 69, member A
chr3_+_142375738 0.148 NM_001172312
PLS1
plastin 1
chr18_+_29027731 0.147 NM_001944
DSG3
desmoglein 3
chr6_+_14117486 0.142 NM_001251901
CD83
CD83 molecule
chr10_+_5005601 0.135 AKR1C1
AKR1C3
aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase)
aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)
chr3_-_196911001 0.135 NM_001204387
NM_001204388
DLG1

discs, large homolog 1 (Drosophila)

chr19_-_56249739 0.133 NM_176820
NLRP9
NLR family, pyrin domain containing 9
chr3_+_130569368 0.133 NM_001199180
NM_001199181
NM_001199182
ATP2C1


ATPase, Ca++ transporting, type 2C, member 1


chrX_-_77914824 0.133 NM_152694
ZCCHC5
zinc finger, CCHC domain containing 5
chr12_+_20963637 0.132 NM_019844
SLCO1B3
solute carrier organic anion transporter family, member 1B3
chr2_+_128403438 0.131 NM_001161415
NM_001161416
NM_001161417
NM_005291
GPR17



G protein-coupled receptor 17



chr7_+_39017608 0.126 NM_001166018
NM_007252
POU6F2

POU class 6 homeobox 2

chrX_+_65382627 0.124 HEPH
hephaestin
chr8_-_15095791 0.123 NM_139167
SGCZ
sarcoglycan, zeta
chr6_-_155777036 0.122 NM_015718
NOX3
NADPH oxidase 3
chr10_+_5005453 0.119 NM_001353
AKR1C1
aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase)
chr8_+_61591358 0.118 CHD7
chromodomain helicase DNA binding protein 7
chr1_+_26503973 0.110 NM_006314
CNKSR1
connector enhancer of kinase suppressor of Ras 1
chr13_+_78109808 0.110 NM_001160706
NM_003843
NM_144777
SCEL


sciellin


chr5_+_68710938 0.110 NM_001038603
NM_001244734
MARVELD2

MARVEL domain containing 2

chrX_-_33357725 0.109 NM_000109
DMD
dystrophin
chr8_-_49833823 0.106 NM_003068
SNAI2
snail homolog 2 (Drosophila)
chr6_-_47253962 0.106 TNFRSF21
tumor necrosis factor receptor superfamily, member 21
chr3_-_57326709 0.106 NM_001142733
ASB14
ankyrin repeat and SOCS box containing 14
chr5_+_140254930 0.105 NM_018903
NM_031864
PCDHA12

protocadherin alpha 12

chr4_-_72649734 0.104 NM_000583
GC
group-specific component (vitamin D binding protein)
chr13_+_43355685 0.104 NM_182508
C13orf30
chromosome 13 open reading frame 30
chr2_+_113816214 0.097 NM_173170
IL36RN
interleukin 36 receptor antagonist
chr4_+_78432905 0.097 NM_006419
CXCL13
chemokine (C-X-C motif) ligand 13
chr15_+_40509628 0.097 NM_001128628
NM_001128629
PAK6

p21 protein (Cdc42/Rac)-activated kinase 6

chr22_-_22863504 0.096 NM_080764
ZNF280B
zinc finger protein 280B
chr6_-_26108320 0.095 NM_005323
HIST1H1T
histone cluster 1, H1t
chr7_-_41742666 0.095 NM_002192
INHBA
inhibin, beta A
chrX_+_91090459 0.094 NM_001168360
NM_001168361
NM_001168362
NM_001168363
PCDH11X



protocadherin 11 X-linked



chr4_-_46125929 0.091 NM_173536
GABRG1
gamma-aminobutyric acid (GABA) A receptor, gamma 1
chr6_-_2840683 0.090 SERPINB1
serpin peptidase inhibitor, clade B (ovalbumin), member 1
chr19_-_49658645 0.089 NM_002152
HRC
histidine rich calcium binding protein
chrX_-_32173585 0.088 NM_004013
NM_004020
NM_004021
NM_004022
NM_004023
DMD




dystrophin




chr12_+_25205488 0.086 LRMP
lymphoid-restricted membrane protein
chr10_-_5045967 0.084 NM_001135241
AKR1C2
aldo-keto reductase family 1, member C2 (dihydrodiol dehydrogenase 2; bile acid binding protein; 3-alpha hydroxysteroid dehydrogenase, type III)
chrX_-_55057408 0.084 NM_000032
NM_001037967
NM_001037968
ALAS2


aminolevulinate, delta-, synthase 2


chr1_+_156254069 0.083 NM_032323
TMEM79
transmembrane protein 79
chr20_-_6104056 0.082 NM_017671
FERMT1
fermitin family member 1
chr6_-_47277646 0.082 NM_014452
TNFRSF21
tumor necrosis factor receptor superfamily, member 21
chr14_-_95599794 0.082 NM_001195573
DICER1
dicer 1, ribonuclease type III
chr12_-_8219001 0.081 C3AR1
complement component 3a receptor 1
chr2_-_142889269 0.079 NM_018557
LRP1B
low density lipoprotein receptor-related protein 1B
chr20_+_62795826 0.077 NM_004535
MYT1
myelin transcription factor 1
chr11_-_83393436 0.076 NM_001142702
DLG2
discs, large homolog 2 (Drosophila)
chr12_-_46633551 0.075 SLC38A1
solute carrier family 38, member 1
chr1_-_247054277 0.074 AHCTF1
AT hook containing transcription factor 1
chr5_+_55149149 0.074 NM_001242636
NM_001242639
IL31RA

interleukin 31 receptor A

chr2_-_158731622 0.073 NM_001105
ACVR1
activin A receptor, type I
chr21_-_42219038 0.073 NM_001389
DSCAM
Down syndrome cell adhesion molecule
chr12_+_56324945 0.073 NM_001345
DGKA
diacylglycerol kinase, alpha 80kDa
chr13_-_52980628 0.073 NM_018676
NM_199263
THSD1

thrombospondin, type I, domain containing 1

chr4_-_87028805 0.073 NM_138981
MAPK10
mitogen-activated protein kinase 10
chr20_+_9198036 0.072 NM_182797
PLCB4
phospholipase C, beta 4
chr3_+_97868169 0.070 NM_001005514
OR5H14
olfactory receptor, family 5, subfamily H, member 14
chr11_+_5509914 0.068 NM_001005163
OR52D1
olfactory receptor, family 52, subfamily D, member 1
chr17_-_39023461 0.068 NM_000223
KRT12
keratin 12
chr3_+_189349215 0.067 NM_001114978
NM_001114979
NM_003722
TP63


tumor protein p63


chr1_+_196743929 0.067 NM_001166624
NM_021023
CFHR3

complement factor H-related 3

chr7_+_93535819 0.066 NM_021955
GNGT1
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1
chr22_+_22735134 0.066 CYAT1
immunoglobulin lambda light chain-like
chr4_-_151770611 0.065 LRBA
LPS-responsive vesicle trafficking, beach and anchor containing
chr16_+_82068958 0.064 HSD17B2
hydroxysteroid (17-beta) dehydrogenase 2
chr17_-_48945338 0.064 NM_001243877
TOB1
transducer of ERBB2, 1
chr1_+_18081807 0.064 NM_030812
ACTL8
actin-like 8
chr19_+_39899749 0.064


chr15_+_74422920 0.062 ISLR2
immunoglobulin superfamily containing leucine-rich repeat 2
chr4_+_90033967 0.062 NM_145715
TIGD2
tigger transposable element derived 2
chr4_+_41614933 0.061 LIMCH1
LIM and calponin homology domains 1
chr5_-_137475076 0.061 NM_003551
NME5
non-metastatic cells 5, protein expressed in (nucleoside-diphosphate kinase)
chr7_-_38313232 0.060 NM_001003799
NM_001003806
TARP

TRGV9
TCR gamma alternate reading frame protein

T cell receptor gamma variable 9
chr16_+_82068910 0.059 HSD17B2
hydroxysteroid (17-beta) dehydrogenase 2
chr15_+_74422742 0.057 NM_020851
ISLR2
immunoglobulin superfamily containing leucine-rich repeat 2
chr1_+_67773046 0.057 NM_001559
IL12RB2
interleukin 12 receptor, beta 2
chr7_-_112430408 0.055 NM_022484
TMEM168
transmembrane protein 168
chr8_-_59412695 0.054 NM_000780
CYP7A1
cytochrome P450, family 7, subfamily A, polypeptide 1
chr1_+_167298382 0.054 POU2F1
POU class 2 homeobox 1
chr7_-_50628744 0.053 NM_000790
NM_001242886
NM_001242887
NM_001242888
NM_001242889
NM_001242890
DDC





dopa decarboxylase (aromatic L-amino acid decarboxylase)





chr17_-_49124128 0.053 NM_001251971
SPAG9
sperm associated antigen 9
chr11_+_58710721 0.053 NM_001220496
NM_080661
GLYATL1

glycine-N-acyltransferase-like 1

chr8_+_80523376 0.053 STMN2
stathmin-like 2
chr1_-_116383323 0.053 NM_001111061
NHLH2
nescient helix loop helix 2
chr2_-_241080072 0.053 NM_148961
OTOS
otospiralin
chr1_+_196621007 0.053 NM_000186
NM_001014975
CFH

complement factor H

chr10_-_17171789 0.052 NM_001081
CUBN
cubilin (intrinsic factor-cobalamin receptor)
chr8_+_32579350 0.052 NM_001159996
NRG1
neuregulin 1
chr3_-_123339178 0.050 MYLK
myosin light chain kinase
chr17_-_38956146 0.050 NM_181535
KRT28
keratin 28
chr6_+_100054649 0.050 NM_021620
PRDM13
PR domain containing 13
chr17_-_10741398 0.049 NM_001101387
PIRT
phosphoinositide-interacting regulator of transient receptor potential channels
chr14_+_39703119 0.049 NM_054024
MIA2
melanoma inhibitory activity 2
chr12_-_11214892 0.049 NM_176887
TAS2R46
taste receptor, type 2, member 46
chrX_+_150884506 0.049 NM_033085
FATE1
fetal and adult testis expressed 1
chr17_-_38938785 0.048 NM_181537
KRT27
keratin 27
chr4_+_41614911 0.047 NM_001112719
NM_001112720
LIMCH1

LIM and calponin homology domains 1

chr4_-_153273683 0.046 NM_018315
FBXW7
F-box and WD repeat domain containing 7
chr10_+_77542518 0.045 NM_032024
C10orf11
chromosome 10 open reading frame 11
chr12_-_71148063 0.045 PTPRR
protein tyrosine phosphatase, receptor type, R
chr1_+_31882411 0.044 NM_001199038
SERINC2
serine incorporator 2
chr10_-_128209996 0.044 NM_001004298
C10orf90
chromosome 10 open reading frame 90
chr8_+_1993157 0.043 NM_003970
MYOM2
myomesin (M-protein) 2, 165kDa
chr3_-_190167597 0.043 NM_207316
TMEM207
transmembrane protein 207
chr9_-_125941304 0.043 STRBP
spermatid perinuclear RNA binding protein
chr3_-_13057130 0.043


chr10_+_29577989 0.043 NM_032517
LYZL1
lysozyme-like 1
chr1_+_81771844 0.043 LPHN2
latrophilin 2
chr5_+_55147206 0.043 NM_001242637
NM_001242638
NM_139017
IL31RA


interleukin 31 receptor A


chr6_+_127898318 0.042 NM_001010905
C6orf58
chromosome 6 open reading frame 58
chr8_-_101315457 0.042 NM_015435
RNF19A
ring finger protein 19A
chr6_+_88182624 0.041 NM_001168398
NM_006416
SLC35A1

solute carrier family 35 (CMP-sialic acid transporter), member A1

chrX_-_15288588 0.041 NM_001168531
ASB9
ankyrin repeat and SOCS box containing 9
chr7_+_94297448 0.041 PEG10
paternally expressed 10
chr12_-_4488707 0.041 NM_020638
FGF23
fibroblast growth factor 23
chr11_+_22696318 0.041 NM_005256
GAS2
growth arrest-specific 2
chr22_-_40289793 0.041 NM_152512
ENTHD1
ENTH domain containing 1
chr18_+_61144143 0.040 NM_002639
SERPINB5
serpin peptidase inhibitor, clade B (ovalbumin), member 5
chr5_+_147443534 0.039 NM_001127698
NM_001127699
NM_006846
SPINK5


serine peptidase inhibitor, Kazal type 5


chr13_+_109248499 0.039 NM_015011
MYO16
myosin XVI
chr9_+_35041101 0.039 NM_001040411
NM_001040412
C9orf131

chromosome 9 open reading frame 131

chr7_-_25268057 0.039 NM_022150
NPVF
neuropeptide VF precursor
chr1_-_193155723 0.038 NM_003783
B3GALT2
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2
chr8_-_93075190 0.038 NM_004349
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr9_+_19290748 0.038 NM_017925
DENND4C
DENN/MADD domain containing 4C
chr1_+_167189948 0.038 NM_001198786
NM_002697
POU2F1

POU class 2 homeobox 1

chr1_-_39407449 0.038 NM_017821
RHBDL2
rhomboid, veinlet-like 2 (Drosophila)
chr4_+_166794409 0.037 NM_001204760
NM_012464
TLL1

tolloid-like 1

chr14_-_57960432 0.037 NM_018168
C14orf105
chromosome 14 open reading frame 105
chr3_-_78666943 0.037 ROBO1
roundabout, axon guidance receptor, homolog 1 (Drosophila)
chr10_-_11574273 0.036 NM_001080491
USP6NL
USP6 N-terminal like
chr13_-_103719195 0.036 NM_000452
SLC10A2
solute carrier family 10 (sodium/bile acid cotransporter family), member 2
chr5_-_156390206 0.036 NM_001146726
NM_138379
TIMD4

T-cell immunoglobulin and mucin domain containing 4

chr9_+_21409132 0.036 NM_002170
IFNA8
interferon, alpha 8
chr2_+_131278666 0.036 NM_032545
NM_001079530
CFC1
CFC1B
cripto, FRL-1, cryptic family 1
cripto, FRL-1, cryptic family 1B
chr7_-_83278478 0.035 NM_012431
SEMA3E
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E
chr13_+_109281569 0.035 NM_001198950
MYO16
myosin XVI
chr8_-_67090690 0.034 NM_000756
CRH
corticotropin releasing hormone
chr17_-_29641087 0.034 EVI2B
ecotropic viral integration site 2B
chr17_-_64225496 0.034 NM_000042
APOH
apolipoprotein H (beta-2-glycoprotein I)
chr1_-_160617042 0.033 NM_003037
SLAMF1
signaling lymphocytic activation molecule family member 1
chr11_-_58980321 0.033 NM_001039396
MPEG1
macrophage expressed 1
chrX_-_15288172 0.033 NM_001031739
NM_001168530
NM_024087
ASB9


ankyrin repeat and SOCS box containing 9


chr1_+_84768333 0.033 NM_001134664
SAMD13
sterile alpha motif domain containing 13
chr3_+_111451326 0.033 NM_001134437
PHLDB2
pleckstrin homology-like domain, family B, member 2
chr11_+_22689653 0.032 NM_177553
GAS2
growth arrest-specific 2
chr4_-_139163222 0.032 NM_014331
SLC7A11
solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
chr1_+_160709038 0.031 NM_021181
SLAMF7
SLAM family member 7
chr19_+_58180302 0.031 NM_152677
ZSCAN4
zinc finger and SCAN domain containing 4
chr2_-_131356859 0.031 NM_032545
NM_001079530
CFC1
CFC1B
cripto, FRL-1, cryptic family 1
cripto, FRL-1, cryptic family 1B
chr12_-_10562744 0.031 NM_001199805
KLRC4-KLRK1
KLRC4-KLRK1 readthrough
chr1_-_76397975 0.030 NM_080868
ASB17
ankyrin repeat and SOCS box containing 17
chr12_-_48963802 0.030 NM_002289
LALBA
lactalbumin, alpha-
chr22_+_22758538 0.030


chr7_+_143412938 0.030 NM_001130026
FAM115C
family with sequence similarity 115, member C
chr1_+_178694273 0.030 NM_152663
RALGPS2
Ral GEF with PH domain and SH3 binding motif 2
chr4_-_76944585 0.030 NM_001565
CXCL10
chemokine (C-X-C motif) ligand 10
chr4_+_41614725 0.030 LIMCH1
LIM and calponin homology domains 1
chrX_+_123234462 0.030 STAG2
stromal antigen 2
chr2_+_128293312 0.029 NM_001080527
MYO7B
myosin VIIB
chr8_-_124749573 0.029 NM_001003954
NM_004306
ANXA13

annexin A13

chr4_+_95376396 0.029 PDLIM5
PDZ and LIM domain 5
chr2_+_27799388 0.029 NM_032266
C2orf16
chromosome 2 open reading frame 16
chr16_+_81272293 0.029 NM_017429
BCMO1
beta-carotene 15,15'-monooxygenase 1
chr2_+_183582667 0.029 DNAJC10
DnaJ (Hsp40) homolog, subfamily C, member 10
chr12_-_71148331 0.028 PTPRR
protein tyrosine phosphatase, receptor type, R
chr21_-_39956823 0.028 NM_001243429
ERG
v-ets erythroblastosis virus E26 oncogene homolog (avian)
chr7_-_92855780 0.028 NM_001039372
HEPACAM2
HEPACAM family member 2

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.58 1.99e-03 GO:0048856 anatomical structure development
1.40 3.87e-03 GO:0032501 multicellular organismal process
1.52 5.66e-03 GO:0007275 multicellular organismal development
12.59 7.34e-03 GO:0008038 neuron recognition
1.48 8.35e-03 GO:0032502 developmental process
1.56 1.64e-02 GO:0048731 system development
2.08 2.86e-02 GO:0050793 regulation of developmental process
1.67 3.02e-02 GO:0030154 cell differentiation
1.69 3.50e-02 GO:0048513 organ development
1.65 3.84e-02 GO:0048869 cellular developmental process
6.48 3.92e-02 GO:0008037 cell recognition
2.18 4.37e-02 GO:2000026 regulation of multicellular organismal development
7.51 4.63e-02 GO:0050909 sensory perception of taste

Nothing significant found in compartment category.

Gene overrepresentation in function category:

enrichment   p-value GO term description
34.61 1.23e-02 GO:0047115 trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity