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• Activity deltas table
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Motif ID: PRDM1.p3

Z-value: 1.801

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr8_+_97506020	3.405		SDC2	syndecan 2
chr20_-_48099178	2.832	NM_004975	KCNB1	potassium voltage-gated channel, Shab-related subfamily, member 1
chr8_+_97506071	2.492		SDC2	syndecan 2
chr2_-_190044330	2.392	NM_000393	COL5A2	collagen, type V, alpha 2
chr11_+_113931228	2.350	NM_001018011	ZBTB16	zinc finger and BTB domain containing 16
chr8_+_97505876	2.173	NM_002998	SDC2	syndecan 2
chrX_-_118827322	1.882	NM_015129 NM_145799 NM_145800 NM_145802	SEPT6	septin 6
chr9_-_16727887	1.874		BNC2	basonuclin 2
chr3_+_8543508	1.799	NM_014583	LMCD1	LIM and cysteine-rich domains 1
chr8_+_97505895	1.766		SDC2	syndecan 2
chr4_-_100242487	1.720	NM_000668	ADH1A ADH1B	alcohol dehydrogenase 1A (class I), alpha polypeptide alcohol dehydrogenase 1B (class I), beta polypeptide
chrX_-_118827060	1.683		SEPT6	septin 6
chr11_+_63304272	1.648	NM_004585	RARRES3	retinoic acid receptor responder (tazarotene induced) 3
chr4_+_186990308	1.648	NM_003265	TLR3	toll-like receptor 3
chr3_-_49851356	1.642	NM_003335	UBA7	ubiquitin-like modifier activating enzyme 7
chrX_+_102883647	1.625	NM_001006640	TCEAL1	transcription elongation factor A (SII)-like 1
chr3_-_49851217	1.618		UBA7	ubiquitin-like modifier activating enzyme 7
chr3_-_114343052	1.574	NM_001164347	ZBTB20	zinc finger and BTB domain containing 20
chr3_+_51977286	1.519		PARP3	poly (ADP-ribose) polymerase family, member 3
chr3_+_8543539	1.464		LMCD1	LIM and cysteine-rich domains 1
chr16_-_67970734	1.464	NM_002801	PSMB10	proteasome (prosome, macropain) subunit, beta type, 10
chr1_+_162602308	1.463		DDR2	discoidin domain receptor tyrosine kinase 2
chr19_+_49977465	1.403	NM_001204502 NM_001459	FLT3LG	fms-related tyrosine kinase 3 ligand
chrX_-_63005212	1.370	NM_001173479	ARHGEF9	Cdc42 guanine nucleotide exchange factor (GEF) 9
chr5_+_131746579	1.365		C5orf56	chromosome 5 open reading frame 56
chr8_+_97657581	1.245		PGCP	plasma glutamate carboxypeptidase
chr3_+_51976274	1.180	NM_001003931 NM_005485	PARP3	poly (ADP-ribose) polymerase family, member 3
chr6_+_32821924	1.178	NM_002800	PSMB9	proteasome (prosome, macropain) subunit, beta type, 9 (large multifunctional peptidase 2)
chrX_+_102883891	1.163	NM_001006639 NM_004780	TCEAL1	transcription elongation factor A (SII)-like 1
chrX_-_118827155	1.130		SEPT6	septin 6
chr16_-_67970651	1.130		PSMB10	proteasome (prosome, macropain) subunit, beta type, 10
chr14_+_24605393	1.095		PSME1	proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)
chr4_-_186578122	1.084	NM_001145674 NM_001145675	SORBS2	sorbin and SH3 domain containing 2
chr4_+_142557722	1.080	NM_000585 NM_172175	IL15	interleukin 15
chr14_+_24605366	1.029	NM_006263 NM_176783	PSME1	proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)
chr2_-_19558371	1.018	NM_145260	OSR1	odd-skipped related 1 (Drosophila)
chr17_+_6659356	1.016		XAF1	XIAP associated factor 1
chr17_+_3379295	1.010	NM_000049	ASPA	aspartoacylase
chr2_-_127864505	1.003	NM_004305 NM_139343 NM_139344 NM_139345 NM_139346 NM_139347 NM_139348 NM_139349 NM_139350 NM_139351	BIN1	bridging integrator 1
chr19_+_49977817	0.947	NM_001204503	FLT3LG	fms-related tyrosine kinase 3 ligand
chrX_-_118827116	0.932		SEPT6	septin 6
chr10_+_69869249	0.901	NM_032578	MYPN	myopalladin
chr17_+_6659155	0.901	NM_017523 NM_199139	XAF1	XIAP associated factor 1
chr8_+_97657592	0.890		PGCP	plasma glutamate carboxypeptidase
chr2_-_99552677	0.884	NM_207362	C2orf55	chromosome 2 open reading frame 55
chr22_-_36556781	0.881	NM_145640	APOL3	apolipoprotein L, 3
chr20_+_388693	0.845	NM_006462 NM_031229	RBCK1	RanBP-type and C3HC4-type zinc finger containing 1
chr20_+_388963	0.793		RBCK1	RanBP-type and C3HC4-type zinc finger containing 1
chr1_-_57045235	0.789	NM_003713	PPAP2B	phosphatidic acid phosphatase type 2B
chr9_+_120466607	0.779		TLR4	toll-like receptor 4
chr10_+_92980507	0.762		PCGF5	polycomb group ring finger 5
chr3_+_69915374	0.759	NM_198177	MITF	microphthalmia-associated transcription factor
chr20_+_389346	0.737		RBCK1	RanBP-type and C3HC4-type zinc finger containing 1
chr17_+_78237389	0.710
chr1_+_162602198	0.695	NM_001014796 NM_006182	DDR2	discoidin domain receptor tyrosine kinase 2
chr2_+_231191877	0.685	NM_138402	SP140L	SP140 nuclear body protein-like
chr11_+_65190267	0.681		NEAT1	nuclear paraspeckle assembly transcript 1 (non-protein coding)
chr10_-_35103894	0.678	NM_001184785 NM_001184786 NM_001184787 NM_001184788 NM_001184789 NM_001184790 NM_001184791 NM_001184792 NM_001184793 NM_001184794 NM_019619	PARD3	par-3 partitioning defective 3 homolog (C. elegans)
chr17_+_41158741	0.642	NM_005533	IFI35	interferon-induced protein 35
chr3_-_160101443	0.633	NM_001190242	IFT80	intraflagellar transport 80 homolog (Chlamydomonas)
chrX_+_10124984	0.631	NM_001830	CLCN4	chloride channel 4
chr1_+_167905796	0.624	NM_001017977 NM_001198956 NM_001198957 NM_018442	DCAF6	DDB1 and CUL4 associated factor 6
chr1_+_167905921	0.604		DCAF6	DDB1 and CUL4 associated factor 6
chr6_-_112575345	0.603		LAMA4	laminin, alpha 4
chr19_+_36239445	0.599		LIN37	lin-37 homolog (C. elegans)
chr8_-_29120571	0.584	NM_015254	KIF13B	kinesin family member 13B
chr1_+_221052845	0.581		HLX	H2.0-like homeobox
chr8_+_134203281	0.571	NM_001204869 NM_001204870 NM_003882 NM_080838	WISP1	WNT1 inducible signaling pathway protein 1
chr1_-_167905078	0.561		BRP44	brain protein 44
chr15_-_37393364	0.558	NM_001220482 NM_002399	MEIS2	Meis homeobox 2
chr9_-_73736513	0.556	NM_001007471	TRPM3	transient receptor potential cation channel, subfamily M, member 3
chr11_-_40315663	0.550	NM_020929	LRRC4C	leucine rich repeat containing 4C
chr2_-_152146373	0.546	NM_004688	NMI	N-myc (and STAT) interactor
chr1_-_167905214	0.544		BRP44	brain protein 44
chr4_+_37892698	0.543	NM_015173	TBC1D1	TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1
chr10_+_92980322	0.540	NM_032373	PCGF5	polycomb group ring finger 5
chr1_-_148176392	0.512
chr14_-_24701561	0.509	NM_001199823 NM_006156	NEDD8-MDP1 NEDD8	NEDD8-MDP1 readthrough neural precursor cell expressed, developmentally down-regulated 8
chr12_+_6561176	0.488	NM_018009	TAPBPL	TAP binding protein-like
chr4_-_186577858	0.455		SORBS2	sorbin and SH3 domain containing 2
chr6_-_112575708	0.450		LAMA4	laminin, alpha 4
chr10_+_63808968	0.440	NM_001244638	ARID5B	AT rich interactive domain 5B (MRF1-like)
chr2_+_175260455	0.440	NM_001193528 NM_024583	SCRN3	secernin 3
chr7_-_105319608	0.438	NM_138495	ATXN7L1	ataxin 7-like 1
chr3_+_185046682	0.411		MAP3K13	mitogen-activated protein kinase kinase kinase 13
chr19_+_36239261	0.402	NM_019104	LIN37	lin-37 homolog (C. elegans)
chr2_+_205410556	0.401		PARD3B	par-3 partitioning defective 3 homolog B (C. elegans)
chr10_+_91092238	0.401	NM_001031683	IFIT3	interferon-induced protein with tetratricopeptide repeats 3
chr13_+_108921976	0.401	NM_001145645 NM_006573	TNFSF13B	tumor necrosis factor (ligand) superfamily, member 13b
chr2_-_200329810	0.399	NM_001172517	SATB2	SATB homeobox 2
chr20_+_13976014	0.398	NM_080676	MACROD2	MACRO domain containing 2
chr15_+_96876568	0.377	NM_001145157	NR2F2	nuclear receptor subfamily 2, group F, member 2
chrX_-_13835187	0.373		GPM6B	glycoprotein M6B
chr22_-_36635552	0.373		APOL2	apolipoprotein L, 2
chr19_-_39735606	0.372	NM_172139	IL28B	interleukin 28B (interferon, lambda 3)
chr6_+_126240369	0.369	NM_001199622	NCOA7	nuclear receptor coactivator 7
chr2_+_239756672	0.364	NM_057179	TWIST2	twist homolog 2 (Drosophila)
chr5_+_139889635	0.364
chr2_+_37311593	0.362	NM_174931	CCDC75	coiled-coil domain containing 75
chr1_-_144997110	0.355	NM_001195260	PDE4DIP	phosphodiesterase 4D interacting protein
chr3_-_187871816	0.354		LPP-AS2	LPP antisense RNA 2 (non-protein coding)
chr1_+_32666201	0.354	NM_024296	CCDC28B	coiled-coil domain containing 28B
chr14_-_24701472	0.354		NEDD8	neural precursor cell expressed, developmentally down-regulated 8
chr13_+_31309690	0.349		ALOX5AP	arachidonate 5-lipoxygenase-activating protein
chr19_+_13105970	0.345	NM_002501	NFIX	nuclear factor I/X (CCAAT-binding transcription factor)
chr12_+_121570630	0.344	NM_002562	P2RX7	purinergic receptor P2X, ligand-gated ion channel, 7
chr15_+_85144219	0.343	NM_001007072 NM_017894 NM_181877	ZSCAN2	zinc finger and SCAN domain containing 2
chr21_+_26934440	0.340		MIR155HG	MIR155 host gene (non-protein coding)
chr19_+_30863318	0.339	NM_014717	ZNF536	zinc finger protein 536
chr1_-_182361311	0.338	NM_001033044 NM_002065	GLUL	glutamate-ammonia ligase
chr6_+_25962978	0.338	NM_006355	TRIM38	tripartite motif containing 38
chr5_-_142815076	0.336	NM_001018074 NM_001018075 NM_001018077	NR3C1	nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr20_+_57470200	0.332		GNAS	GNAS complex locus
chr1_+_104159953	0.331	NM_000699	AMY2A	amylase, alpha 2A (pancreatic)
chr16_+_50775960	0.330	NM_001042355 NM_015247	CYLD	cylindromatosis (turban tumor syndrome)
chr8_+_96145968	0.328		PLEKHF2	pleckstrin homology domain containing, family F (with FYVE domain) member 2
chr9_+_120466625	0.318		TLR4	toll-like receptor 4
chr14_+_24701624	0.316	NM_001002000 NM_001002001	GMPR2	guanosine monophosphate reductase 2
chr2_+_205410465	0.314	NM_057177 NM_152526 NM_205863	PARD3B	par-3 partitioning defective 3 homolog B (C. elegans)
chr5_+_32710742	0.304	NM_001204376	NPR3	natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C)
chr13_+_108922474	0.303		TNFSF13B	tumor necrosis factor (ligand) superfamily, member 13b
chr13_+_108922205	0.301		TNFSF13B	tumor necrosis factor (ligand) superfamily, member 13b
chr16_+_50776012	0.297	NM_001042412	CYLD	cylindromatosis (turban tumor syndrome)
chr13_+_31309644	0.296	NM_001629	ALOX5AP	arachidonate 5-lipoxygenase-activating protein
chr5_+_161277702	0.296	NM_001127648	GABRA1	gamma-aminobutyric acid (GABA) A receptor, alpha 1
chr6_-_32811773	0.295	NM_148919	PSMB8	proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional peptidase 7)
chr7_+_55980330	0.292	NM_182633	ZNF713	zinc finger protein 713
chr2_+_202122753	0.288	NM_001080125	CASP8	caspase 8, apoptosis-related cysteine peptidase
chr2_-_231084600	0.287	NM_004509 NM_004510 NM_080424	SP110	SP110 nuclear body protein
chr19_+_39759153	0.284	NM_172138	IL28A	interleukin 28A (interferon, lambda 2)
chr8_-_145060563	0.281		PARP10	poly (ADP-ribose) polymerase family, member 10
chr8_-_93075190	0.275	NM_004349	RUNX1T1	runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr11_+_77532159	0.273	NM_024684	C11orf67	chromosome 11 open reading frame 67
chr14_-_24701559	0.271		NEDD8	neural precursor cell expressed, developmentally down-regulated 8
chr8_+_96145942	0.266	NM_024613	PLEKHF2	pleckstrin homology domain containing, family F (with FYVE domain) member 2
chr3_+_187871473	0.261	NM_001167672	LPP	LIM domain containing preferred translocation partner in lipoma
chr6_-_130031278	0.253	NM_033515	ARHGAP18	Rho GTPase activating protein 18
chr5_-_37184945	0.249		C5orf42	chromosome 5 open reading frame 42
chr16_-_73092533	0.247	NM_001164766	ZFHX3	zinc finger homeobox 3
chr7_+_5253816	0.245	NM_001033520	WIPI2	WD repeat domain, phosphoinositide interacting 2
chr11_+_64008412	0.244	NM_004470	FKBP2	FK506 binding protein 2, 13kDa
chr1_+_226012974	0.240	NM_000120	EPHX1	epoxide hydrolase 1, microsomal (xenobiotic)
chr6_-_112575766	0.238	NM_001105206 NM_001105207 NM_001105208 NM_001105209 NM_002290	LAMA4	laminin, alpha 4
chr22_+_39436608	0.238	NM_001006666 NM_145298	APOBEC3F	apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3F
chr10_+_91061705	0.236	NM_001547	IFIT2	interferon-induced protein with tetratricopeptide repeats 2
chr14_-_24615794	0.234	NM_002818	PSME2	proteasome (prosome, macropain) activator subunit 2 (PA28 beta)
chr19_-_23578226	0.234	NM_003430	ZNF91	zinc finger protein 91
chr12_-_57824787	0.229		R3HDM2	R3H domain containing 2
chr2_+_132480063	0.225	NM_013310	C2orf27A	chromosome 2 open reading frame 27A
chr2_+_175260505	0.224		SCRN3	secernin 3
chr1_-_244006885	0.222	NM_001206729	AKT3	v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)
chr2_-_145275086	0.221		ZEB2	zinc finger E-box binding homeobox 2
chr9_+_18474078	0.220	NM_001040272 NM_052866	ADAMTSL1	ADAMTS-like 1
chrX_-_13835012	0.209		GPM6B	glycoprotein M6B
chr9_+_18474138	0.199		ADAMTSL1	ADAMTS-like 1
chr1_+_110453232	0.197	NM_000757 NM_172210 NM_172212	CSF1	colony stimulating factor 1 (macrophage)
chr3_+_119013216	0.195	NM_020754	ARHGAP31	Rho GTPase activating protein 31
chr6_-_112575880	0.192		LAMA4	laminin, alpha 4
chr6_+_36973409	0.192	NM_173558	FGD2	FYVE, RhoGEF and PH domain containing 2
chr6_+_32811895	0.186
chr2_-_144994905	0.183	NM_024659	GTDC1	glycosyltransferase-like domain containing 1
chr2_+_231280933	0.181		SP100	SP100 nuclear antigen
chr6_-_24936177	0.181		FAM65B	family with sequence similarity 65, member B
chr9_-_14868974	0.180		FREM1	FRAS1 related extracellular matrix 1
chr2_+_231280870	0.180	NM_001080391 NM_001206701 NM_001206702 NM_001206703 NM_003113	SP100	SP100 nuclear antigen
chr20_+_13976263	0.177		MACROD2	MACRO domain containing 2
chr20_+_388717	0.174		RBCK1	RanBP-type and C3HC4-type zinc finger containing 1
chr10_+_91087601	0.171	NM_001549	IFIT3	interferon-induced protein with tetratricopeptide repeats 3
chr20_+_56964162	0.170	NM_001195677 NM_004738	VAPB	VAMP (vesicle-associated membrane protein)-associated protein B and C
chr14_-_69262959	0.167	NM_001244701	ZFP36L1	zinc finger protein 36, C3H type-like 1
chr2_+_205410716	0.167		PARD3B	par-3 partitioning defective 3 homolog B (C. elegans)
chr2_-_175260349	0.167	NM_004882	CIR1	corepressor interacting with RBPJ, 1
chr20_-_47894591	0.158	NM_021035	ZNFX1	zinc finger, NFX1-type containing 1
chr1_-_150780705	0.157	NM_000396	CTSK	cathepsin K
chr6_+_26440699	0.153	NM_001242803 NM_006994 NM_197974	BTN3A3	butyrophilin, subfamily 3, member A3
chr20_+_33464404	0.153		ACSS2	acyl-CoA synthetase short-chain family member 2
chr7_+_99621083	0.152		ZKSCAN1	zinc finger with KRAB and SCAN domains 1
chr5_+_161277391	0.150	NM_001127647	GABRA1	gamma-aminobutyric acid (GABA) A receptor, alpha 1
chr11_+_71710971	0.148	NM_001145055	IL18BP	interleukin 18 binding protein
chr11_+_46402333	0.148	NM_001012334	MDK	midkine (neurite growth-promoting factor 2)
chr2_+_166150340	0.143	NM_021007	SCN2A	sodium channel, voltage-gated, type II, alpha subunit
chr10_-_27529263	0.141	NM_145698	ACBD5	acyl-CoA binding domain containing 5
chr12_+_51318515	0.140	NM_014033	METTL7A	methyltransferase like 7A
chr7_+_134464161	0.136	NM_004342 NM_033138 NM_033157	CALD1	caldesmon 1
chr2_+_237993954	0.136	NM_006710 NM_198189	COPS8	COP9 constitutive photomorphogenic homolog subunit 8 (Arabidopsis)
chr10_-_82049178	0.132	NM_000429	MAT1A	methionine adenosyltransferase I, alpha
chr2_+_121554866	0.132	NM_005270	GLI2	GLI family zinc finger 2
chr10_-_94003002	0.131	NM_001178137	CPEB3	cytoplasmic polyadenylation element binding protein 3
chr9_-_21077804	0.130	NM_002176	IFNB1	interferon, beta 1, fibroblast
chr14_-_24615772	0.129		PSME2	proteasome (prosome, macropain) activator subunit 2 (PA28 beta)
chrX_-_13835213	0.128		GPM6B	glycoprotein M6B
chr10_-_13749622	0.128		FRMD4A	FERM domain containing 4A
chr9_+_137533643	0.128	NM_000093	COL5A1	collagen, type V, alpha 1
chr9_+_33624214	0.125		ANXA2P2	annexin A2 pseudogene 2
chrX_-_13835313	0.125	NM_001001995 NM_001001996 NM_005278	GPM6B	glycoprotein M6B
chr2_-_191878883	0.122		STAT1	signal transducer and activator of transcription 1, 91kDa
chr4_+_87856152	0.120	NM_001166693	AFF1	AF4/FMR2 family, member 1
chr7_+_120702818	0.120		C7orf58	chromosome 7 open reading frame 58
chr1_+_151372009	0.120	NM_002796	PSMB4	proteasome (prosome, macropain) subunit, beta type, 4
chr1_+_110453456	0.119		CSF1	colony stimulating factor 1 (macrophage)

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
2.90	8.99e-05	GO:0010605	negative regulation of macromolecule metabolic process
11.15	1.01e-04	GO:0060337	type I interferon-mediated signaling pathway
11.15	1.01e-04	GO:0071357	cellular response to type I interferon
10.97	1.17e-04	GO:0034340	response to type I interferon
2.84	2.37e-04	GO:0031324	negative regulation of cellular metabolic process
1.90	2.81e-04	GO:0051171	regulation of nitrogen compound metabolic process
2.69	4.90e-04	GO:0009892	negative regulation of metabolic process
1.93	7.80e-04	GO:0048522	positive regulation of cellular process
8.04	1.75e-03	GO:0030330	DNA damage response, signal transduction by p53 class mediator
3.26	2.09e-03	GO:0051253	negative regulation of RNA metabolic process
1.81	4.08e-03	GO:0048518	positive regulation of biological process
10.14	5.32e-03	GO:0006521	regulation of cellular amino acid metabolic process
3.17	5.65e-03	GO:0045892	negative regulation of transcription, DNA-dependent
2.28	7.51e-03	GO:0002376	immune system process
7.88	7.75e-03	GO:0031575	mitotic cell cycle G1/S transition checkpoint
7.88	7.75e-03	GO:0071779	G1/S transition checkpoint
2.96	9.26e-03	GO:0010629	negative regulation of gene expression
6.46	1.08e-02	GO:0042770	signal transduction in response to DNA damage
7.49	1.13e-02	GO:2000045	regulation of G1/S transition of mitotic cell cycle
2.92	1.15e-02	GO:0045934	negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.86	1.17e-02	GO:0051252	regulation of RNA metabolic process
8.81	1.38e-02	GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
8.81	1.38e-02	GO:0072395	signal transduction involved in cell cycle checkpoint
8.81	1.38e-02	GO:0072401	signal transduction involved in DNA integrity checkpoint
8.81	1.38e-02	GO:0072404	signal transduction involved in G1/S transition checkpoint
8.81	1.38e-02	GO:0072413	signal transduction involved in mitotic cell cycle checkpoint
8.81	1.38e-02	GO:0072422	signal transduction involved in DNA damage checkpoint
8.81	1.38e-02	GO:0072431	signal transduction involved in mitotic cell cycle G1/S transition DNA damage checkpoint
8.81	1.38e-02	GO:0072474	signal transduction involved in mitotic cell cycle G1/S checkpoint
2.88	1.39e-02	GO:0051172	negative regulation of nitrogen compound metabolic process
8.40	1.90e-02	GO:0033238	regulation of cellular amine metabolic process
8.40	1.90e-02	GO:0071158	positive regulation of cell cycle arrest
2.47	1.96e-02	GO:0051704	multi-organism process
1.85	2.03e-02	GO:0006355	regulation of transcription, DNA-dependent
8.02	2.57e-02	GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
1.60	2.69e-02	GO:0031323	regulation of cellular metabolic process
2.60	2.84e-02	GO:0006955	immune response
7.91	2.84e-02	GO:0031571	mitotic cell cycle G1/S transition DNA damage checkpoint
1.74	3.33e-02	GO:0010468	regulation of gene expression
7.68	3.43e-02	GO:0051352	negative regulation of ligase activity
7.68	3.43e-02	GO:0051444	negative regulation of ubiquitin-protein ligase activity
2.49	3.61e-02	GO:0044093	positive regulation of molecular function
7.57	3.77e-02	GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
1.35	4.21e-02	GO:0050794	regulation of cellular process
3.36	4.47e-02	GO:0045087	innate immune response
1.61	4.56e-02	GO:0060255	regulation of macromolecule metabolic process
2.73	4.95e-02	GO:2000113	negative regulation of cellular macromolecule biosynthetic process

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
9.75	2.64e-04	GO:0000502	proteasome complex
19.19	8.25e-04	GO:0005839	proteasome core complex
76.76	2.96e-02	GO:0071797	LUBAC complex

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
18.28	1.21e-03	GO:0004298	threonine-type endopeptidase activity
18.28	1.21e-03	GO:0070003	threonine-type peptidase activity
2.40	2.13e-03	GO:0001071	nucleic acid binding transcription factor activity
2.40	2.13e-03	GO:0003700	sequence-specific DNA binding transcription factor activity
1.17	2.82e-02	GO:0005488	binding
3.96	4.59e-02	GO:0005125	cytokine activity
1.73	4.77e-02	GO:0008270	zinc ion binding