Motif ID: PRDM1.p3

Z-value: 1.801


Transcription factors associated with PRDM1.p3:

Gene SymbolEntrez IDGene Name
PRDM1 639 PR domain containing 1, with ZNF domain

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
PRDM1chr6_+_106534188-0.831.1e-02Click!


Activity profile for motif PRDM1.p3.

activity profile for motif PRDM1.p3


Sorted Z-values histogram for motif PRDM1.p3

Sorted Z-values for motif PRDM1.p3



Network of associatons between targets according to the STRING database.



First level regulatory network of PRDM1.p3

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr8_+_97506020 3.405 SDC2
syndecan 2
chr20_-_48099178 2.832 NM_004975
 KCNB1
potassium voltage-gated channel, Shab-related subfamily, member 1
chr8_+_97506071 2.492 SDC2
syndecan 2
chr2_-_190044330 2.392 NM_000393
 COL5A2
collagen, type V, alpha 2
chr11_+_113931228 2.350 NM_001018011
 ZBTB16
zinc finger and BTB domain containing 16
chr8_+_97505876 2.173 NM_002998
 SDC2
syndecan 2
chrX_-_118827322 1.882 NM_015129
NM_145799
NM_145800
NM_145802
 SEPT6



septin 6



chr9_-_16727887 1.874 BNC2
basonuclin 2
chr3_+_8543508 1.799 NM_014583
 LMCD1
LIM and cysteine-rich domains 1
chr8_+_97505895 1.766 SDC2
syndecan 2
chr4_-_100242487 1.720 NM_000668
 ADH1A
ADH1B
alcohol dehydrogenase 1A (class I), alpha polypeptide
alcohol dehydrogenase 1B (class I), beta polypeptide
chrX_-_118827060 1.683 SEPT6
septin 6
chr11_+_63304272 1.648 NM_004585
 RARRES3
retinoic acid receptor responder (tazarotene induced) 3
chr4_+_186990308 1.648 NM_003265
 TLR3
toll-like receptor 3
chr3_-_49851356 1.642 NM_003335
 UBA7
ubiquitin-like modifier activating enzyme 7
chrX_+_102883647 1.625 NM_001006640
 TCEAL1
transcription elongation factor A (SII)-like 1
chr3_-_49851217 1.618 UBA7
ubiquitin-like modifier activating enzyme 7
chr3_-_114343052 1.574 NM_001164347
 ZBTB20
zinc finger and BTB domain containing 20
chr3_+_51977286 1.519 PARP3
poly (ADP-ribose) polymerase family, member 3
chr3_+_8543539 1.464 LMCD1
LIM and cysteine-rich domains 1

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 47 entries
enrichment   p-value GO term description
11.15 1.01e-04 GO:0060337 type I interferon-mediated signaling pathway
11.15 1.01e-04 GO:0071357 cellular response to type I interferon
10.97 1.17e-04 GO:0034340 response to type I interferon
10.14 5.32e-03 GO:0006521 regulation of cellular amino acid metabolic process
8.81 1.38e-02 GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
8.81 1.38e-02 GO:0072395 signal transduction involved in cell cycle checkpoint
8.81 1.38e-02 GO:0072401 signal transduction involved in DNA integrity checkpoint
8.81 1.38e-02 GO:0072404 signal transduction involved in G1/S transition checkpoint
8.81 1.38e-02 GO:0072413 signal transduction involved in mitotic cell cycle checkpoint
8.81 1.38e-02 GO:0072422 signal transduction involved in DNA damage checkpoint
8.81 1.38e-02 GO:0072431 signal transduction involved in mitotic cell cycle G1/S transition DNA damage checkpoint
8.81 1.38e-02 GO:0072474 signal transduction involved in mitotic cell cycle G1/S checkpoint
8.40 1.90e-02 GO:0033238 regulation of cellular amine metabolic process
8.40 1.90e-02 GO:0071158 positive regulation of cell cycle arrest
8.04 1.75e-03 GO:0030330 DNA damage response, signal transduction by p53 class mediator
8.02 2.57e-02 GO:0051436 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
7.91 2.84e-02 GO:0031571 mitotic cell cycle G1/S transition DNA damage checkpoint
7.88 7.75e-03 GO:0031575 mitotic cell cycle G1/S transition checkpoint
7.88 7.75e-03 GO:0071779 G1/S transition checkpoint
7.68 3.43e-02 GO:0051352 negative regulation of ligase activity

Gene overrepresentation in compartment category:

Showing 1 to 3 of 3 entries
enrichment   p-value GO term description
76.76 2.96e-02 GO:0071797 LUBAC complex
19.19 8.25e-04 GO:0005839 proteasome core complex
9.75 2.64e-04 GO:0000502 proteasome complex

Gene overrepresentation in function category:

Showing 1 to 7 of 7 entries
enrichment   p-value GO term description
18.28 1.21e-03 GO:0004298 threonine-type endopeptidase activity
18.28 1.21e-03 GO:0070003 threonine-type peptidase activity
3.96 4.59e-02 GO:0005125 cytokine activity
2.40 2.13e-03 GO:0001071 nucleic acid binding transcription factor activity
2.40 2.13e-03 GO:0003700 sequence-specific DNA binding transcription factor activity
1.73 4.77e-02 GO:0008270 zinc ion binding
1.17 2.82e-02 GO:0005488 binding