Motif ID: PRRX1,2.p2

Z-value: 1.263


Transcription factors associated with PRRX1,2.p2:

Gene SymbolEntrez IDGene Name
PRRX1 5396 paired related homeobox 1
PRRX2 51450 paired related homeobox 2

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
PRRX1chr1_+_1706333120.801.8e-02Click!
PRRX2chr9_+_132427919-0.531.7e-01Click!


Activity profile for motif PRRX1,2.p2.

activity profile for motif PRRX1,2.p2


Sorted Z-values histogram for motif PRRX1,2.p2

Sorted Z-values for motif PRRX1,2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of PRRX1,2.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr13_-_38172862 4.095 NM_001135934
NM_001135935
NM_001135936
NM_006475
 POSTN



periostin, osteoblast specific factor



chr9_-_95186559 3.996 NM_005014
 OMD
osteomodulin
chr5_+_71502700 3.822 MAP1B
microtubule-associated protein 1B
chr2_+_189839132 3.447 COL3A1
collagen, type III, alpha 1
chr12_-_91576805 3.387 NM_001920
 DCN
decorin
chr10_+_69869249 3.086 NM_032578
 MYPN
myopalladin
chr5_-_75919051 3.045 NM_004101
 F2RL2
coagulation factor II (thrombin) receptor-like 2
chr14_-_92413738 2.807 FBLN5
fibulin 5
chr12_-_91576579 2.684 DCN
decorin
chr2_+_189839078 2.564 NM_000090
 COL3A1
collagen, type III, alpha 1
chr6_-_46293628 2.524 NM_005822
 RCAN2
regulator of calcineurin 2
chr6_+_72926144 2.414 NM_001168409
 RIMS1
regulating synaptic membrane exocytosis 1
chr2_+_210444364 2.227 NM_002374
NM_031845
NM_031847
 MAP2


microtubule-associated protein 2


chr13_+_102104941 2.204 NM_004791
 ITGBL1
integrin, beta-like 1 (with EGF-like repeat domains)
chr2_-_207082626 2.142 NM_001098199
NM_005279
 GPR1

G protein-coupled receptor 1

chr2_+_189839113 2.113 COL3A1
collagen, type III, alpha 1
chr8_-_120651019 2.047 NM_001040092
NM_001130863
NM_006209
 ENPP2


ectonucleotide pyrophosphatase/phosphodiesterase 2


chr5_-_111312522 2.043 NM_001142474
NM_001142475
 C5orf13

chromosome 5 open reading frame 13

chr5_+_67586466 2.019 NM_181504
 PIK3R1
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr16_+_53133063 1.979 CHD9
chromodomain helicase DNA binding protein 9

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 5 of 5 entries
enrichment   p-value GO term description
1.41 4.79e-02 GO:0010629 negative regulation of gene expression
1.20 2.33e-02 GO:0048519 negative regulation of biological process
1.10 2.40e-02 GO:0050794 regulation of cellular process
1.09 4.55e-02 GO:0050789 regulation of biological process
1.08 4.99e-02 GO:0065007 biological regulation

Gene overrepresentation in compartment category:

Showing 1 to 1 of 1 entries
enrichment   p-value GO term description
1.11 4.08e-03 GO:0005634 nucleus

Gene overrepresentation in function category:

Showing 1 to 6 of 6 entries
enrichment   p-value GO term description
1.54 5.81e-03 GO:0003712 transcription cofactor activity
1.53 6.56e-03 GO:0000988 protein binding transcription factor activity
1.53 6.56e-03 GO:0000989 transcription factor binding transcription factor activity
1.37 2.40e-02 GO:0005509 calcium ion binding
1.09 4.44e-03 GO:0005515 protein binding
1.06 8.39e-04 GO:0005488 binding