Motif ID: RBPJ.p2

Z-value: 0.725


Transcription factors associated with RBPJ.p2:

Gene SymbolEntrez IDGene Name
RBPJ 3516 recombination signal binding protein for immunoglobulin kappa J region

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
RBPJchr4_+_26321307-0.865.7e-03Click!


Activity profile for motif RBPJ.p2.

activity profile for motif RBPJ.p2


Sorted Z-values histogram for motif RBPJ.p2

Sorted Z-values for motif RBPJ.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of RBPJ.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr2_-_161056573 1.216 NM_000888
ITGB6
integrin, beta 6
chr2_-_161056762 1.082 ITGB6
integrin, beta 6
chr17_+_7942351 1.075 NM_001039130
NM_001039131
NM_001141
ALOX15B


arachidonate 15-lipoxygenase, type B


chr5_+_68788387 0.855 NM_001205254
OCLN
occludin
chr1_+_86889768 0.806 NM_006536
CLCA2
chloride channel accessory 2
chr16_+_69141442 0.803 NM_005329
HAS3
hyaluronan synthase 3
chrX_+_68048792 0.744 NM_004429
EFNB1
ephrin-B1
chr2_+_220492286 0.706 NM_005070
NM_201574
SLC4A3

solute carrier family 4, anion exchanger, member 3

chr20_+_6748744 0.698 NM_001200
BMP2
bone morphogenetic protein 2
chr18_-_28622624 0.670 NM_001941
NM_024423
DSC3

desmocollin 3

chr19_-_51504799 0.638 NM_007196
NM_144505
NM_144506
NM_144507
KLK8



kallikrein-related peptidase 8



chr8_+_102504836 0.582 GRHL2
grainyhead-like 2 (Drosophila)
chr8_+_82644663 0.568 NM_152284
CHMP4C
charged multivesicular body protein 4C
chr8_+_102504661 0.557 NM_024915
GRHL2
grainyhead-like 2 (Drosophila)
chr19_-_54676813 0.550 NM_001145303
NM_144686
TMC4

transmembrane channel-like 4

chr13_+_37006408 0.545 NM_001111045
NM_003914
CCNA1

cyclin A1

chr2_+_131674223 0.540 NM_015320
NM_032995
ARHGEF4

Rho guanine nucleotide exchange factor (GEF) 4

chr1_+_155100304 0.539 NM_004428
NM_182685
EFNA1

ephrin-A1

chr16_+_68771214 0.534 CDH1
cadherin 1, type 1, E-cadherin (epithelial)
chr6_+_30851860 0.532 NM_001954
DDR1
discoidin domain receptor tyrosine kinase 1
chr4_-_84256304 0.508 NM_001166498
NM_006665
HPSE

heparanase

chr4_-_84255999 0.508 HPSE
heparanase
chr4_-_84256012 0.483 NM_001098540
HPSE
heparanase
chr16_+_68771192 0.482 NM_004360
CDH1
cadherin 1, type 1, E-cadherin (epithelial)
chr13_+_37006628 0.474 CCNA1
cyclin A1
chr10_-_5446781 0.453 NM_001171864
NM_024803
TUBAL3

tubulin, alpha-like 3

chr4_-_84255895 0.430 NM_001199830
HPSE
heparanase
chr8_+_18248754 0.429 NM_000015
NAT2
N-acetyltransferase 2 (arylamine N-acetyltransferase)
chr6_+_126070895 0.412 HEY2
hairy/enhancer-of-split related with YRPW motif 2
chr14_-_54421269 0.406 NM_130851
BMP4
bone morphogenetic protein 4
chr20_+_44637539 0.406 NM_004994
MMP9
matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
chr5_+_36608430 0.388 NM_001166695
SLC1A3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr9_+_115913266 0.388 SLC31A2
solute carrier family 31 (copper transporters), member 2
chr16_+_57662301 0.386 NM_001145771
NM_001145772
NM_001145773
NM_201524
NM_201525
GPR56




G protein-coupled receptor 56




chr2_-_160761192 0.373 LY75-CD302
LY75
LY75-CD302 readthrough
lymphocyte antigen 75
chr18_-_47376156 0.373 MYO5B
myosin VB
chr6_-_13408368 0.365 NM_001242630
GFOD1
glucose-fructose oxidoreductase domain containing 1
chr10_+_47746919 0.356 NM_001630
ANXA8L2
ANXA8
annexin A8-like 2
annexin A8
chr8_+_123794043 0.347 ZHX2
zinc fingers and homeoboxes 2
chr10_-_38146978 0.344 ZNF248
zinc finger protein 248
chr1_+_955468 0.342 NM_198576
AGRN
agrin
chr17_-_7493389 0.328 NM_006942
SOX15
SRY (sex determining region Y)-box 15
chr8_+_123793988 0.325 ZHX2
zinc fingers and homeoboxes 2
chr19_+_46733008 0.320 NM_198541
IGFL1
IGF-like family member 1
chr8_+_28559143 0.315 NM_001440
EXTL3
exostoses (multiple)-like 3
chr3_+_193853937 0.313 HES1
hairy and enhancer of split 1, (Drosophila)
chr15_+_59730272 0.304 NM_152450
FAM81A
family with sequence similarity 81, member A
chr6_-_32805819 0.301 TAP2
transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
chr9_+_22446783 0.295 NM_022160
DMRTA1
DMRT-like family A1
chr1_-_93342706 0.288 NM_001252271
FAM69A
family with sequence similarity 69, member A
chr17_-_7991020 0.285 NM_001139
ALOX12B
arachidonate 12-lipoxygenase, 12R type
chrX_+_105969875 0.276 NM_194463
RNF128
ring finger protein 128
chr10_-_126138549 0.272 NM_001146340
NKX1-2
NK1 homeobox 2
chr10_-_118764727 0.268 KIAA1598
KIAA1598
chr6_-_107435635 0.267 NM_001080450
BEND3
BEN domain containing 3
chr22_-_46933066 0.267 NM_014246
CELSR1
cadherin, EGF LAG seven-pass G-type receptor 1 (flamingo homolog, Drosophila)
chr1_+_955609 0.265 AGRN
agrin
chr3_+_39371196 0.252 NM_005201
CCR8
chemokine (C-C motif) receptor 8
chr14_-_92302612 0.252 NM_001128595
NM_152332
TC2N

tandem C2 domains, nuclear

chrX_+_152907892 0.248 NM_001395
DUSP9
dual specificity phosphatase 9
chr10_+_75673346 0.245 PLAU
plasminogen activator, urokinase
chr8_+_123793894 0.239 NM_014943
ZHX2
zinc fingers and homeoboxes 2
chr8_-_125579395 0.238 MTSS1
metastasis suppressor 1
chr6_+_143382030 0.236 AIG1
androgen-induced 1
chr10_-_118764559 0.235 KIAA1598
KIAA1598
chr18_+_61554938 0.234 NM_001143818
NM_002575
SERPINB2

serpin peptidase inhibitor, clade B (ovalbumin), member 2

chr9_+_72435730 0.233 NM_001010940
C9orf135
chromosome 9 open reading frame 135
chr8_+_28559010 0.230 EXTL3
exostoses (multiple)-like 3
chr1_-_223537400 0.230 NM_001037175
NM_017982
SUSD4

sushi domain containing 4

chr1_+_155099935 0.229 EFNA1
ephrin-A1
chr2_+_111435801 0.228


chr17_-_56160564 0.227


chr17_+_73720775 0.223 NM_001005619
ITGB4
integrin, beta 4
chr6_+_73331570 0.223 NM_001160130
NM_001160132
NM_001160133
NM_001160134
NM_019842
KCNQ5




potassium voltage-gated channel, KQT-like subfamily, member 5




chr22_+_32753853 0.219 NM_001098535
RFPL3
ret finger protein-like 3
chr18_+_61442611 0.217 NM_003784
SERPINB7
serpin peptidase inhibitor, clade B (ovalbumin), member 7
chr6_+_49518358 0.216 C6orf141
chromosome 6 open reading frame 141
chr6_+_126070738 0.215 HEY2
hairy/enhancer-of-split related with YRPW motif 2
chr2_+_159825083 0.214 NM_001145909
NM_033394
TANC1

tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1

chr3_-_112564789 0.214 NM_001008784
NM_001199215
CD200R1L

CD200 receptor 1-like

chr5_+_140213968 0.214 NM_018910
NM_031852
PCDHA7

protocadherin alpha 7

chr5_-_176836535 0.210 NM_000505
F12
coagulation factor XII (Hageman factor)
chr7_-_16844606 0.209 NM_006408
AGR2
anterior gradient 2 homolog (Xenopus laevis)
chr2_-_163174816 0.206 NM_022168
IFIH1
interferon induced with helicase C domain 1
chr2_-_192015733 0.206 STAT4
signal transducer and activator of transcription 4
chr17_+_47572592 0.205 NM_002507
NGFR
nerve growth factor receptor
chr5_+_68788118 0.205 NM_002538
OCLN
occludin
chr1_-_228135587 0.202 NM_003395
WNT9A
wingless-type MMTV integration site family, member 9A
chr19_+_38810461 0.201 NM_004823
KCNK6
potassium channel, subfamily K, member 6
chrX_+_24483343 0.200 NM_001142386
NM_005391
PDK3

pyruvate dehydrogenase kinase, isozyme 3

chrX_-_31284946 0.198 NM_004015
NM_004016
NM_004017
NM_004018
NM_004019
DMD




dystrophin




chr10_-_118765087 0.197 NM_001127211
NM_018330
KIAA1598

KIAA1598

chrX_-_100662905 0.196 NM_000169
GLA
galactosidase, alpha
chr1_+_955536 0.196


chrX_-_100662788 0.195 GLA
galactosidase, alpha
chr5_+_178368193 0.194 NM_001178089
NM_001178090
NM_182594
ZNF454


zinc finger protein 454


chr20_+_43935490 0.193 NM_014276
RBPJL
recombination signal binding protein for immunoglobulin kappa J region-like
chrX_-_40594949 0.192 MED14
mediator complex subunit 14
chr18_-_66382218 0.192 TMX3
thioredoxin-related transmembrane protein 3
chr6_-_32806009 0.192 TAP2
transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
chr1_-_153363544 0.191 NM_002964
S100A8
S100 calcium binding protein A8
chr15_+_73976621 0.190 NM_001024736
NM_025240
CD276

CD276 molecule

chr10_-_43048029 0.189 ZNF37BP
zinc finger protein 37B, pseudogene
chr6_+_71123105 0.187 NM_001105531
NM_020819
FAM135A

family with sequence similarity 135, member A

chr2_+_218990735 0.184 NM_001557
CXCR2
chemokine (C-X-C motif) receptor 2
chr19_-_44143943 0.183 NM_145296
CADM4
cell adhesion molecule 4
chr11_-_87908551 0.183 NM_022337
RAB38
RAB38, member RAS oncogene family
chr1_+_152486977 0.182 NM_019060
CRCT1
cysteine-rich C-terminal 1
chr19_+_45843997 0.182 NM_177417
KLC3
kinesin light chain 3
chr14_-_23285011 0.182 NM_001126105
SLC7A7
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr3_-_51533996 0.181 NM_001171904
NM_014703
VPRBP

Vpr (HIV-1) binding protein

chr1_-_12677347 0.178 NM_004753
DHRS3
dehydrogenase/reductase (SDR family) member 3
chr7_-_45151272 0.177 TBRG4
transforming growth factor beta regulator 4
chr2_-_160761266 0.173 NM_001198759
NM_001198760
NM_002349
LY75-CD302

LY75
LY75-CD302 readthrough

lymphocyte antigen 75
chr2_+_102615456 0.172 NM_173343
IL1R2
interleukin 1 receptor, type II
chr15_+_90728118 0.171 NM_020210
SEMA4B
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B
chr16_+_577833 0.170 NM_005632
SOLH
small optic lobes homolog (Drosophila)
chr21_+_46875402 0.170 NM_030582
COL18A1
collagen, type XVIII, alpha 1
chr15_+_91260575 0.169 NM_000057
BLM
Bloom syndrome, RecQ helicase-like
chr2_+_85360373 0.168 NM_031283
TCF7L1
transcription factor 7-like 1 (T-cell specific, HMG-box)
chr7_-_75115536 0.165 NM_001099415
POM121C
POM121 membrane glycoprotein C
chr4_-_89080010 0.165 NM_004827
ABCG2
ATP-binding cassette, sub-family G (WHITE), member 2
chr14_+_94393687 0.164 NM_001207074
NM_001207073
NM_001207072
FAM181A


family with sequence similarity 181, member A


chr8_-_124408688 0.164 NM_014109
ATAD2
ATPase family, AAA domain containing 2
chr1_-_40098639 0.161 HEYL
hairy/enhancer-of-split related with YRPW motif-like
chrX_-_153236621 0.159 NM_005334
HCFC1
host cell factor C1 (VP16-accessory protein)
chr9_+_139780939 0.158 NM_021138
TRAF2
TNF receptor-associated factor 2
chr6_-_136847078 0.157 NM_001198608
NM_001198609
NM_001198611
MAP7


microtubule-associated protein 7


chr16_+_81528953 0.156 NM_030629
CMIP
c-Maf inducing protein
chr11_+_66512241 0.156 C11orf80
chromosome 11 open reading frame 80
chr9_-_140196702 0.155 NM_001004354
NRARP
NOTCH-regulated ankyrin repeat protein
chr14_-_93214873 0.154 NM_001008530
NM_005606
LGMN

legumain

chr8_-_144699695 0.154 TSTA3
tissue specific transplantation antigen P35B
chr7_-_128045995 0.154 NM_001142573
NM_001142574
NM_001142575
IMPDH1


IMP (inosine 5'-monophosphate) dehydrogenase 1


chr12_-_71031174 0.153 NM_001109754
PTPRB
protein tyrosine phosphatase, receptor type, B
chr16_+_68771236 0.151 CDH1
cadherin 1, type 1, E-cadherin (epithelial)
chr1_-_27226928 0.149 GPATCH3
G patch domain containing 3
chr4_-_130014405 0.149 NM_144643
SCLT1
sodium channel and clathrin linker 1
chr4_-_120548329 0.148 NM_033430
PDE5A
phosphodiesterase 5A, cGMP-specific
chr15_+_73976689 0.148 CD276
CD276 molecule
chr14_-_92333856 0.144 NM_001128596
TC2N
tandem C2 domains, nuclear
chr10_+_103892786 0.143 NM_015062
PPRC1
peroxisome proliferator-activated receptor gamma, coactivator-related 1
chr14_-_90798253 0.140 NM_017970
C14orf102
chromosome 14 open reading frame 102
chr10_+_118083939 0.139 NM_198515
C10orf96
chromosome 10 open reading frame 96
chr5_-_693413 0.139 NM_007030
TPPP
tubulin polymerization promoting protein
chr14_+_39736529 0.138 CTAGE5
CTAGE family, member 5
chr15_+_73976777 0.137 CD276
CD276 molecule
chr1_-_59042827 0.137 TACSTD2
tumor-associated calcium signal transducer 2
chr2_-_170219012 0.136 NM_004525
LRP2
low density lipoprotein receptor-related protein 2
chr4_+_89299874 0.135 NM_001165136
NM_017912
HERC6

hect domain and RLD 6

chr7_-_16505292 0.133 NM_015464
SOSTDC1
sclerostin domain containing 1
chr6_-_146285225 0.133 NM_001042683
NM_173082
SHPRH

SNF2 histone linker PHD RING helicase

chr6_+_71123147 0.133 FAM135A
family with sequence similarity 135, member A
chr19_+_56989482 0.132 LOC100128252
uncharacterized LOC100128252
chr1_+_151483861 0.131 NM_020770
CGN
cingulin
chr1_+_205473768 0.131 CDK18
cyclin-dependent kinase 18
chr11_+_66512164 0.131 NM_024650
C11orf80
chromosome 11 open reading frame 80
chr15_+_89164522 0.129 NM_022767
AEN
apoptosis enhancing nuclease
chr6_+_42531951 0.129 UBR2
ubiquitin protein ligase E3 component n-recognin 2
chr1_-_160681552 0.128 NM_001778
CD48
CD48 molecule
chr3_-_123339423 0.128 NM_053031
NM_053032
MYLK

myosin light chain kinase

chr16_+_30194730 0.127 NM_001193333
NM_007074
CORO1A

coronin, actin binding protein, 1A

chr15_+_73976720 0.127 CD276
CD276 molecule
chr2_+_183580960 0.126 NM_018981
DNAJC10
DnaJ (Hsp40) homolog, subfamily C, member 10
chr2_+_233562042 0.126 GIGYF2
GRB10 interacting GYF protein 2
chr1_-_2461683 0.126 NM_001010926
HES5
hairy and enhancer of split 5 (Drosophila)
chr6_+_126070813 0.125 HEY2
hairy/enhancer-of-split related with YRPW motif 2
chr14_-_23623493 0.124 NM_182728
SLC7A8
solute carrier family 7 (amino acid transporter light chain, L system), member 8
chr15_+_41136178 0.124 NM_003710
NM_181642
SPINT1

serine peptidase inhibitor, Kunitz type 1

chr8_-_144699621 0.123 TSTA3
tissue specific transplantation antigen P35B
chr1_-_27481400 0.123 NM_003047
SLC9A1
solute carrier family 9 (sodium/hydrogen exchanger), member 1
chr4_+_20255234 0.122 NM_004787
SLIT2
slit homolog 2 (Drosophila)
chr19_+_50145369 0.122 NM_021228
SCAF1
SR-related CTD-associated factor 1
chrX_-_70331297 0.121 NM_000206
IL2RG
interleukin 2 receptor, gamma
chr7_-_100254048 0.121 NM_016188
ACTL6B
actin-like 6B
chr11_-_102668892 0.120 NM_001145938
NM_002421
MMP1

matrix metallopeptidase 1 (interstitial collagenase)

chrX_-_54824672 0.120 NM_198510
ITIH6
inter-alpha-trypsin inhibitor heavy chain family, member 6
chr3_+_142442855 0.119


chr5_-_6633347 0.118 NM_001193455
NM_017755
NSUN2

NOP2/Sun domain family, member 2

chr4_+_1795004 0.118 NM_000142
NM_001163213
NM_022965
FGFR3


fibroblast growth factor receptor 3


chrX_-_153095996 0.118 NM_032512
PDZD4
PDZ domain containing 4
chr2_+_220325533 0.118 NM_001173476
SPEG
SPEG complex locus
chr14_+_97263681 0.117 NM_003384
VRK1
vaccinia related kinase 1
chr4_-_120549115 0.117 NM_033437
PDE5A
phosphodiesterase 5A, cGMP-specific
chr1_+_156254069 0.117 NM_032323
TMEM79
transmembrane protein 79
chr1_-_59043165 0.115 NM_002353
TACSTD2
tumor-associated calcium signal transducer 2
chr6_+_129204285 0.114 NM_000426
NM_001079823
LAMA2

laminin, alpha 2

chr10_+_44101854 0.114 NM_145312
ZNF485
zinc finger protein 485
chr20_+_32319765 0.114 NM_032819
ZNF341
zinc finger protein 341
chr14_-_24658010 0.112 NM_024658
IPO4
importin 4
chr10_+_44101883 0.112 ZNF485
zinc finger protein 485
chr14_-_24657986 0.110 IPO4
importin 4
chr1_-_11714738 0.110 NM_012168
FBXO2
F-box protein 2
chr2_-_192015751 0.109 STAT4
signal transducer and activator of transcription 4
chr10_-_52383611 0.109 NM_147156
SGMS1
sphingomyelin synthase 1
chr3_-_189838673 0.107 LEPREL1
leprecan-like 1
chr11_+_61129831 0.107 TMEM138
transmembrane protein 138
chr14_+_69658193 0.107 NM_001193360
NM_001193361
NM_018199
EXD2


exonuclease 3'-5' domain containing 2


chr16_-_68482373 0.107 NM_018667
SMPD3
sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II)
chr16_+_57653909 0.106 NM_001145770
NM_005682
GPR56

G protein-coupled receptor 56


Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Gene overrepresentation in function category:

enrichment   p-value GO term description
2.95 1.60e-02 GO:0008135 translation factor activity, nucleic acid binding