Motif ID: RFX1..5_RFXANK_RFXAP.p2

Z-value: 1.219


Transcription factors associated with RFX1..5_RFXANK_RFXAP.p2:

Gene SymbolEntrez IDGene Name
RFX1 5989 regulatory factor X, 1 (influences HLA class II expression)
RFX2 5990 regulatory factor X, 2 (influences HLA class II expression)
RFX3 5991 regulatory factor X, 3 (influences HLA class II expression)
RFX4 5992 regulatory factor X, 4 (influences HLA class II expression)
RFX5 5993 regulatory factor X, 5 (influences HLA class II expression)
RFXANK 8625 regulatory factor X-associated ankyrin-containing protein
RFXAP 5994 regulatory factor X-associated protein

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
RFXANKchr19_+_19303732,
chr19_+_19303007		0.791.9e-02Click!
RFXAPchr13_+_37393306-0.571.4e-01Click!
RFX5chr1_-_1513197170.512.0e-01Click!
RFX2chr19_-_6110561-0.432.9e-01Click!
RFX1chr19_-_14117096-0.413.1e-01Click!
RFX3chr9_-_3525973-0.344.1e-01Click!
RFX4chr12_+_1069949140.157.2e-01Click!


Activity profile for motif RFX1..5_RFXANK_RFXAP.p2.

activity profile for motif RFX1..5_RFXANK_RFXAP.p2


Sorted Z-values histogram for motif RFX1..5_RFXANK_RFXAP.p2

Sorted Z-values for motif RFX1..5_RFXANK_RFXAP.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of RFX1..5_RFXANK_RFXAP.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr5_-_179780314 1.589 NM_005110
 GFPT2
glutamine-fructose-6-phosphate transaminase 2
chr17_-_5404304 1.532 NM_001162371
 LOC728392
uncharacterized LOC728392
chr14_-_60337350 1.396 NM_021136
 RTN1
reticulon 1
chr14_+_105941061 1.349 NM_001312
 CRIP2
cysteine-rich protein 2
chr5_+_92918924 1.156 NM_005654
 NR2F1
nuclear receptor subfamily 2, group F, member 1
chr11_+_133938819 0.956 NM_001205329
NM_032801
 JAM3

junctional adhesion molecule 3

chr3_-_197676755 0.923 NM_001134435
 IQCG
IQ motif containing G
chr14_+_100259445 0.918 NM_001008707
NM_004434
 EML1

echinoderm microtubule associated protein like 1

chr1_+_42928873 0.901 CCDC30
coiled-coil domain containing 30
chr11_+_133938965 0.820 JAM3
junctional adhesion molecule 3
chr8_+_120428551 0.819 NM_002514
 NOV
nephroblastoma overexpressed gene
chr6_+_30524662 0.808 PRR3
proline rich 3
chr2_-_175869910 0.800 NM_001822
NM_001025201
 CHN1

chimerin (chimaerin) 1

chr16_+_29823557 0.795 PRRT2
proline-rich transmembrane protein 2
chr1_-_109656478 0.779 NM_001122961
 C1orf194
chromosome 1 open reading frame 194
chr22_-_31063786 0.777 NM_152511
 DUSP18
dual specificity phosphatase 18
chr22_-_43485333 0.767 NM_012263
 TTLL1
tubulin tyrosine ligase-like family, member 1
chr1_-_48937791 0.745 NM_019073
 SPATA6
spermatogenesis associated 6
chr3_-_196439067 0.737 NM_032898
 CEP19
centrosomal protein 19kDa
chr12_-_63328663 0.719 NM_020700
 PPM1H
protein phosphatase, Mg2+/Mn2+ dependent, 1H

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 4 of 4 entries
enrichment   p-value GO term description
8.37 1.06e-05 GO:0042384 cilium assembly
6.02 6.17e-04 GO:0060271 cilium morphogenesis
4.73 3.95e-03 GO:0010927 cellular component assembly involved in morphogenesis
4.67 3.45e-04 GO:0030031 cell projection assembly

Gene overrepresentation in compartment category:

Showing 1 to 12 of 12 entries
enrichment   p-value GO term description
7.36 1.94e-08 GO:0005930 axoneme
7.00 2.41e-05 GO:0005932 microtubule basal body
6.73 1.32e-04 GO:0035085 cilium axoneme
5.49 5.68e-05 GO:0044441 cilium part
4.29 2.33e-08 GO:0005929 cilium
2.25 4.81e-02 GO:0005874 microtubule
1.97 1.32e-03 GO:0015630 microtubule cytoskeleton
1.22 1.69e-05 GO:0005737 cytoplasm
1.15 5.89e-05 GO:0044424 intracellular part
1.14 1.64e-04 GO:0005622 intracellular
1.13 3.86e-02 GO:0043226 organelle
1.13 4.34e-02 GO:0043229 intracellular organelle

Nothing significant found in function category.