Motif ID: RUNX1..3.p2

Z-value: 1.186


Transcription factors associated with RUNX1..3.p2:

Gene SymbolEntrez IDGene Name
RUNX1 861 runt-related transcription factor 1
RUNX2 860 runt-related transcription factor 2
RUNX3 864 runt-related transcription factor 3

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
RUNX1chr21_-_36259408-0.763.0e-02Click!
RUNX3chr1_-_25256767,
chr1_-_25256364		-0.621.0e-01Click!
RUNX2chr6_+_453898180.591.3e-01Click!


Activity profile for motif RUNX1..3.p2.

activity profile for motif RUNX1..3.p2


Sorted Z-values histogram for motif RUNX1..3.p2

Sorted Z-values for motif RUNX1..3.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of RUNX1..3.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr3_+_45067750 1.537 NM_003278
 CLEC3B
C-type lectin domain family 3, member B
chr8_-_12973752 1.379 NM_001164271
 DLC1
deleted in liver cancer 1
chr6_+_72926462 1.245 NM_001168410
 RIMS1
regulating synaptic membrane exocytosis 1
chrX_+_9431314 1.126 NM_001139466
NM_001139467
NM_001139468
 TBL1X


transducin (beta)-like 1X-linked


chr2_+_128175989 1.039 NM_000312
 PROC
protein C (inactivator of coagulation factors Va and VIIIa)
chr2_+_33359607 0.925 NM_000627
NM_001166264
NM_001166265
NM_001166266
 LTBP1



latent transforming growth factor beta binding protein 1



chr2_+_189839078 0.915 NM_000090
 COL3A1
collagen, type III, alpha 1
chr9_-_95186559 0.904 NM_005014
 OMD
osteomodulin
chr16_+_53133063 0.899 CHD9
chromodomain helicase DNA binding protein 9
chr8_-_60031545 0.853 NM_014729
 TOX
thymocyte selection-associated high mobility group box
chr5_+_156696351 0.849 NM_014376
 CYFIP2
cytoplasmic FMR1 interacting protein 2
chr19_+_51226638 0.847 CLEC11A
C-type lectin domain family 11, member A
chr11_-_119293848 0.827 THY1
Thy-1 cell surface antigen
chr14_-_61115906 0.818 NM_005982
 SIX1
SIX homeobox 1
chr9_+_120466607 0.772 TLR4
toll-like receptor 4
chr1_-_184006491 0.751 GLT25D2
glycosyltransferase 25 domain containing 2
chr5_+_139505519 0.749 NM_001007189
 IGIP
IgA-inducing protein homolog (Bos taurus)
chr6_-_132272311 0.745 NM_001901
 CTGF
connective tissue growth factor
chr2_+_128176019 0.736 PROC
protein C (inactivator of coagulation factors Va and VIIIa)
chr19_+_51226593 0.718 NM_002975
 CLEC11A
C-type lectin domain family 11, member A

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 5 of 5 entries
enrichment   p-value GO term description
1.79 5.48e-03 GO:0001775 cell activation
1.51 4.73e-02 GO:0009611 response to wounding
1.47 1.00e-02 GO:0002376 immune system process
1.24 4.56e-02 GO:0007165 signal transduction
1.23 2.45e-02 GO:0023052 signaling

Gene overrepresentation in compartment category:

Showing 1 to 9 of 9 entries
enrichment   p-value GO term description
2.58 1.80e-02 GO:0005925 focal adhesion
2.48 2.30e-02 GO:0030055 cell-substrate junction
2.46 3.84e-02 GO:0005924 cell-substrate adherens junction
1.57 2.40e-03 GO:0005615 extracellular space
1.52 6.83e-04 GO:0044421 extracellular region part
1.42 4.54e-03 GO:0031226 intrinsic to plasma membrane
1.42 6.65e-03 GO:0005887 integral to plasma membrane
1.31 9.33e-03 GO:0005576 extracellular region
1.30 6.78e-03 GO:0044459 plasma membrane part

Gene overrepresentation in function category:

Showing 1 to 2 of 2 entries
enrichment   p-value GO term description
2.17 1.64e-02 GO:0005126 cytokine receptor binding
1.46 1.73e-02 GO:0005102 receptor binding