Motif ID: RXR{A,B,G}.p2

Z-value: 0.750


Transcription factors associated with RXR{A,B,G}.p2:

Gene SymbolEntrez IDGene Name
RXRA 6256 retinoid X receptor, alpha
RXRB 6257 retinoid X receptor, beta
RXRG 6258 retinoid X receptor, gamma

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
RXRBchr6_-_331681630.772.5e-02Click!
RXRAchr9_+_1372183130.383.6e-01Click!
RXRGchr1_-_1654144990.137.6e-01Click!


Activity profile for motif RXR{A,B,G}.p2.

activity profile for motif RXR{A,B,G}.p2


Sorted Z-values histogram for motif RXR{A,B,G}.p2

Sorted Z-values for motif RXR{A,B,G}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of RXR{A,B,G}.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr5_+_92920592 0.958 NR2F1
NR2F2
nuclear receptor subfamily 2, group F, member 1
nuclear receptor subfamily 2, group F, member 2
chr17_+_47074749 0.842 NM_001160423
NM_006546
 IGF2BP1

insulin-like growth factor 2 mRNA binding protein 1

chr5_-_172755418 0.762 STC2
stanniocalcin 2
chr1_-_236228382 0.703 NID1
nidogen 1
chr5_-_172755195 0.683 STC2
stanniocalcin 2
chr17_-_76921453 0.592 NM_003255
 TIMP2
TIMP metallopeptidase inhibitor 2
chr1_+_183774214 0.581 RGL1
ral guanine nucleotide dissociation stimulator-like 1
chrX_-_106960028 0.557 TSC22D3
TSC22 domain family, member 3
chr10_-_81205091 0.494 NM_153367
 ZCCHC24
zinc finger, CCHC domain containing 24
chr11_+_113931228 0.480 NM_001018011
 ZBTB16
zinc finger and BTB domain containing 16
chr6_-_46459010 0.470 NM_001251974
 RCAN2
regulator of calcineurin 2
chr15_+_33010174 0.468 NM_001191322
NM_001191323
NM_013372
 GREM1


gremlin 1


chr1_-_212873306 0.464 NM_018664
 BATF3
basic leucine zipper transcription factor, ATF-like 3
chr2_-_127864505 0.463 NM_004305
NM_139343
NM_139344
NM_139345
NM_139346
NM_139347
NM_139348
NM_139349
NM_139350
NM_139351
 BIN1









bridging integrator 1









chr1_-_72748147 0.460 NM_173808
 NEGR1
neuronal growth regulator 1
chr11_-_74022609 0.455 NM_182904
 P4HA3
prolyl 4-hydroxylase, alpha polypeptide III
chr7_+_94023872 0.438 NM_000089
 COL1A2
collagen, type I, alpha 2
chr2_+_241938254 0.433 NM_001080437
 SNED1
sushi, nidogen and EGF-like domains 1
chr1_-_72748491 0.432


chr7_+_94024201 0.428 COL1A2
collagen, type I, alpha 2

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 30 entries
enrichment   p-value GO term description
3.54 8.83e-05 GO:0006119 oxidative phosphorylation
3.41 1.65e-03 GO:0042773 ATP synthesis coupled electron transport
3.41 1.65e-03 GO:0042775 mitochondrial ATP synthesis coupled electron transport
3.00 2.01e-06 GO:0022904 respiratory electron transport chain
2.59 2.03e-05 GO:0045333 cellular respiration
2.22 7.66e-03 GO:0022900 electron transport chain
1.70 6.00e-03 GO:0007264 small GTPase mediated signal transduction
1.55 2.26e-02 GO:0051253 negative regulation of RNA metabolic process
1.53 1.22e-02 GO:0010629 negative regulation of gene expression
1.53 4.93e-02 GO:0045892 negative regulation of transcription, DNA-dependent
1.50 4.03e-02 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.40 3.65e-02 GO:0010605 negative regulation of macromolecule metabolic process
1.36 1.22e-02 GO:0051641 cellular localization
1.32 2.26e-02 GO:0009653 anatomical structure morphogenesis
1.32 4.17e-02 GO:0035556 intracellular signal transduction
1.25 1.79e-02 GO:0051252 regulation of RNA metabolic process
1.25 3.19e-02 GO:0048523 negative regulation of cellular process
1.24 2.62e-02 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.23 2.90e-02 GO:0010468 regulation of gene expression
1.23 3.17e-02 GO:0048522 positive regulation of cellular process

Gene overrepresentation in compartment category:

Showing 1 to 20 of 32 entries
enrichment   p-value GO term description
4.18 4.00e-02 GO:0005753 mitochondrial proton-transporting ATP synthase complex
3.03 2.20e-02 GO:0005747 mitochondrial respiratory chain complex I
3.03 2.20e-02 GO:0030964 NADH dehydrogenase complex
3.03 2.20e-02 GO:0045271 respiratory chain complex I
2.63 5.94e-03 GO:0070469 respiratory chain
2.48 1.69e-02 GO:0005604 basement membrane
2.24 1.92e-03 GO:0044455 mitochondrial membrane part
1.94 4.98e-03 GO:0031252 cell leading edge
1.52 3.86e-02 GO:0031966 mitochondrial membrane
1.44 8.17e-03 GO:0031975 envelope
1.44 8.88e-03 GO:0031967 organelle envelope
1.43 2.40e-02 GO:0044429 mitochondrial part
1.33 7.91e-06 GO:0005829 cytosol
1.33 3.73e-03 GO:0005654 nucleoplasm
1.28 1.33e-04 GO:0031974 membrane-enclosed lumen
1.27 2.66e-04 GO:0043233 organelle lumen
1.27 5.32e-04 GO:0070013 intracellular organelle lumen
1.27 3.76e-03 GO:0031981 nuclear lumen
1.25 2.57e-03 GO:0044428 nuclear part
1.22 9.83e-10 GO:0005634 nucleus

Gene overrepresentation in function category:

Showing 1 to 3 of 3 entries
enrichment   p-value GO term description
1.24 7.14e-03 GO:0003677 DNA binding
1.18 7.16e-11 GO:0005515 protein binding
1.09 4.75e-07 GO:0005488 binding