Motif ID: SNAI1..3.p2

Z-value: 6.890


Transcription factors associated with SNAI1..3.p2:

Gene SymbolEntrez IDGene Name
SNAI1 6615 snail homolog 1 (Drosophila)
SNAI2 6591 snail homolog 2 (Drosophila)
SNAI3 333929 snail homolog 3 (Drosophila)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
SNAI3chr16_-_887528790.611.1e-01Click!
SNAI2chr8_-_498338230.502.1e-01Click!
SNAI1chr20_+_485995110.413.1e-01Click!


Activity profile for motif SNAI1..3.p2.

activity profile for motif SNAI1..3.p2


Sorted Z-values histogram for motif SNAI1..3.p2

Sorted Z-values for motif SNAI1..3.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of SNAI1..3.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr1_+_60280462 25.035 NM_015888
 HOOK1
hook homolog 1 (Drosophila)
chr19_+_38755238 20.448 SPINT2
serine peptidase inhibitor, Kunitz type, 2
chr19_+_38755422 20.269 SPINT2
serine peptidase inhibitor, Kunitz type, 2
chr16_+_68679229 19.466 CDH3
cadherin 3, type 1, P-cadherin (placental)
chr16_+_68771214 18.669 CDH1
cadherin 1, type 1, E-cadherin (epithelial)
chr6_-_136871542 17.824 MAP7
microtubule-associated protein 7
chr19_+_38755097 17.672 NM_001166103
NM_021102
 SPINT2

serine peptidase inhibitor, Kunitz type, 2

chr14_-_61747956 17.664 TMEM30B
transmembrane protein 30B
chr19_+_35739282 16.981 LSR
lipolysis stimulated lipoprotein receptor
chr16_+_68771192 16.758 NM_004360
 CDH1
cadherin 1, type 1, E-cadherin (epithelial)
chr1_+_183155393 16.749 LAMC2
laminin, gamma 2
chr1_+_183155361 16.433 LAMC2
laminin, gamma 2
chr1_+_183155173 15.903 NM_005562
NM_018891
 LAMC2

laminin, gamma 2

chr17_-_7165788 15.653 CLDN7
claudin 7
chr1_+_1981902 15.379 NM_002744
 PRKCZ
protein kinase C, zeta
chr16_+_68679198 15.293 CDH3
cadherin 3, type 1, P-cadherin (placental)
chr19_-_10697907 14.846 NM_005498
 AP1M2
adaptor-related protein complex 1, mu 2 subunit
chr17_-_7166263 14.693 NM_001185023
NM_001307
 CLDN7

claudin 7

chr14_-_61748510 14.529 NM_001017970
 TMEM30B
transmembrane protein 30B
chr8_+_95653272 14.231 ESRP1
epithelial splicing regulatory protein 1

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 15 of 15 entries
enrichment   p-value GO term description
1.70 1.10e-02 GO:0034330 cell junction organization
1.27 1.72e-02 GO:0006811 ion transport
1.27 4.15e-02 GO:0055085 transmembrane transport
1.27 4.62e-02 GO:0044093 positive regulation of molecular function
1.24 1.06e-02 GO:0002376 immune system process
1.20 4.76e-03 GO:0007166 cell surface receptor linked signaling pathway
1.17 7.57e-07 GO:0023052 signaling
1.17 1.08e-05 GO:0007165 signal transduction
1.14 1.91e-02 GO:0048856 anatomical structure development
1.14 4.11e-02 GO:0048731 system development
1.13 3.74e-04 GO:0051716 cellular response to stimulus
1.13 2.55e-02 GO:0007275 multicellular organismal development
1.12 3.81e-02 GO:0051179 localization
1.08 5.95e-11 GO:0009987 cellular process
1.07 9.79e-03 GO:0065007 biological regulation

Gene overrepresentation in compartment category:

Showing 1 to 19 of 19 entries
enrichment   p-value GO term description
1.57 1.57e-02 GO:0070161 anchoring junction
1.54 1.79e-03 GO:0016323 basolateral plasma membrane
1.50 3.08e-02 GO:0005911 cell-cell junction
1.38 1.35e-02 GO:0009986 cell surface
1.37 2.00e-04 GO:0030054 cell junction
1.28 1.75e-03 GO:0005626 insoluble fraction
1.28 2.29e-03 GO:0005624 membrane fraction
1.25 1.10e-09 GO:0044459 plasma membrane part
1.25 2.39e-04 GO:0005887 integral to plasma membrane
1.24 5.19e-04 GO:0031226 intrinsic to plasma membrane
1.20 4.40e-02 GO:0000267 cell fraction
1.18 1.52e-02 GO:0012505 endomembrane system
1.11 7.26e-03 GO:0071944 cell periphery
1.11 7.26e-03 GO:0005886 plasma membrane
1.10 2.15e-05 GO:0044425 membrane part
1.09 1.16e-06 GO:0016020 membrane
1.09 7.95e-03 GO:0016021 integral to membrane
1.09 9.36e-03 GO:0031224 intrinsic to membrane
1.06 1.87e-02 GO:0005737 cytoplasm

Gene overrepresentation in function category:

Showing 1 to 11 of 11 entries
enrichment   p-value GO term description
1.94 1.82e-03 GO:0015294 solute:cation symporter activity
1.67 1.93e-02 GO:0015293 symporter activity
1.33 8.50e-03 GO:0008324 cation transmembrane transporter activity
1.28 1.32e-02 GO:0015075 ion transmembrane transporter activity
1.18 2.48e-03 GO:0032553 ribonucleotide binding
1.18 2.48e-03 GO:0032555 purine ribonucleotide binding
1.18 3.06e-03 GO:0017076 purine nucleotide binding
1.18 2.88e-02 GO:0032559 adenyl ribonucleotide binding
1.18 3.06e-02 GO:0030554 adenyl nucleotide binding
1.17 9.03e-03 GO:0035639 purine ribonucleoside triphosphate binding
1.09 7.19e-05 GO:0005515 protein binding