Motif ID: SOX2.p2

Z-value: 0.575


Transcription factors associated with SOX2.p2:

Gene SymbolEntrez IDGene Name
SOX2 6657 SRY (sex determining region Y)-box 2

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
SOX2chr3_+_181429711-0.452.7e-01Click!


Activity profile for motif SOX2.p2.

activity profile for motif SOX2.p2


Sorted Z-values histogram for motif SOX2.p2

Sorted Z-values for motif SOX2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of SOX2.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr7_+_26400503 1.516 NM_001199837
 SNX10
sorting nexin 10
chr2_-_161056762 1.319 ITGB6
integrin, beta 6
chr12_-_52886971 1.014 NM_005554
 KRT6A
keratin 6A
chr11_-_16424391 0.823 NM_001145819
NM_017508
 SOX6

SRY (sex determining region Y)-box 6

chr18_+_29027731 0.766 NM_001944
 DSG3
desmoglein 3
chr18_-_74728677 0.751 MBP
myelin basic protein
chr12_-_67072881 0.736 NM_001178074
NM_021150
 GRIP1

glutamate receptor interacting protein 1

chr7_-_83824216 0.733 NM_006080
 SEMA3A
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr8_+_32504250 0.610 NM_013959
 NRG1
neuregulin 1
chr3_+_189349215 0.597 NM_001114978
NM_001114979
NM_003722
 TP63


tumor protein p63


chr3_+_189507448 0.568 NM_001114980
NM_001114981
NM_001114982
 TP63


tumor protein p63


chr8_+_124194751 0.552 NM_032899
NM_207006
 FAM83A

family with sequence similarity 83, member A

chr10_-_105845619 0.546 NM_000494
 COL17A1
collagen, type XVII, alpha 1
chr8_-_80993009 0.545 NM_001025252
 TPD52
tumor protein D52
chr3_-_151034514 0.530 NM_023915
 GPR87
G protein-coupled receptor 87
chr5_+_140213968 0.514 NM_018910
NM_031852
 PCDHA7

protocadherin alpha 7

chr2_-_165424993 0.512 GRB14
growth factor receptor-bound protein 14
chr10_-_105845556 0.511 COL17A1
collagen, type XVII, alpha 1
chr7_-_41742666 0.509 NM_002192
 INHBA
inhibin, beta A
chr10_-_123356158 0.509 NM_001144915
 FGFR2
fibroblast growth factor receptor 2

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 23 entries
enrichment   p-value GO term description
2.56 2.57e-02 GO:0050671 positive regulation of lymphocyte proliferation
2.52 3.34e-02 GO:0032946 positive regulation of mononuclear cell proliferation
2.49 4.32e-02 GO:0070665 positive regulation of leukocyte proliferation
1.49 4.09e-03 GO:2000026 regulation of multicellular organismal development
1.44 1.30e-06 GO:0007399 nervous system development
1.38 2.17e-02 GO:0022607 cellular component assembly
1.34 4.75e-02 GO:0044085 cellular component biogenesis
1.33 3.40e-08 GO:0048731 system development
1.31 1.33e-09 GO:0007275 multicellular organismal development
1.30 8.77e-08 GO:0048856 anatomical structure development
1.30 7.39e-04 GO:0030154 cell differentiation
1.28 2.41e-03 GO:0048869 cellular developmental process
1.27 3.28e-08 GO:0032502 developmental process
1.27 2.51e-02 GO:0048513 organ development
1.22 2.02e-04 GO:0023052 signaling
1.20 3.77e-03 GO:0071840 cellular component organization or biogenesis
1.20 9.56e-03 GO:0016043 cellular component organization
1.19 3.02e-02 GO:0007165 signal transduction
1.18 2.96e-05 GO:0032501 multicellular organismal process
1.13 8.25e-05 GO:0065007 biological regulation

Gene overrepresentation in compartment category:

Showing 1 to 5 of 5 entries
enrichment   p-value GO term description
1.86 2.04e-02 GO:0030424 axon
1.54 2.66e-02 GO:0045202 synapse
1.12 9.89e-03 GO:0005634 nucleus
1.03 1.77e-02 GO:0044464 cell part
1.03 1.84e-02 GO:0005623 cell

Gene overrepresentation in function category:

Showing 1 to 2 of 2 entries
enrichment   p-value GO term description
2.86 1.61e-02 GO:0005070 SH3/SH2 adaptor activity
1.11 1.13e-03 GO:0005515 protein binding