Motif ID: SOX5.p2

Z-value: 0.644


Transcription factors associated with SOX5.p2:

Gene SymbolEntrez IDGene Name
SOX5 6660 SRY (sex determining region Y)-box 5

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
SOX5chr12_-_24103953-0.502.0e-01Click!


Activity profile for motif SOX5.p2.

activity profile for motif SOX5.p2


Sorted Z-values histogram for motif SOX5.p2

Sorted Z-values for motif SOX5.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of SOX5.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr14_-_92413738 1.770 FBLN5
fibulin 5
chr14_-_92414004 1.392 NM_006329
 FBLN5
fibulin 5
chr1_+_163038564 1.140 NM_005613
 RGS4
regulator of G-protein signaling 4
chr2_+_189839132 0.799 COL3A1
collagen, type III, alpha 1
chr8_-_108510094 0.760 NM_001146
NM_001199859
 ANGPT1

angiopoietin 1

chr3_-_114790221 0.674 NM_001164343
 ZBTB20
zinc finger and BTB domain containing 20
chr6_-_46293404 0.600 RCAN2
regulator of calcineurin 2
chr5_-_111312522 0.541 NM_001142474
NM_001142475
 C5orf13

chromosome 5 open reading frame 13

chr1_+_163038934 0.527 NM_001113381
 RGS4
regulator of G-protein signaling 4
chr5_-_147286064 0.523 NM_206966
 C5orf46
chromosome 5 open reading frame 46
chr9_-_95166827 0.515 NM_014057
NM_033014
 OGN

osteoglycin

chr5_+_110407389 0.466 NM_033035
 TSLP
thymic stromal lymphopoietin
chr8_-_93075190 0.431 NM_004349
 RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr5_+_67588395 0.407 NM_001242466
 PIK3R1
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr5_-_111092918 0.395 NM_004772
 C5orf13
chromosome 5 open reading frame 13
chr5_-_158526698 0.383 NM_024007
 EBF1
early B-cell factor 1
chr5_-_111093251 0.351 NM_001142479
NM_001142480
NM_001142478
 C5orf13


chromosome 5 open reading frame 13


chr4_+_124317884 0.349 NM_199327
 SPRY1
sprouty homolog 1, antagonist of FGF signaling (Drosophila)
chr12_-_29937691 0.341 NM_175861
 TMTC1
transmembrane and tetratricopeptide repeat containing 1
chr5_-_111093030 0.334 NM_001142482
NM_001142481
 C5orf13

chromosome 5 open reading frame 13


Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 19 of 19 entries
enrichment   p-value GO term description
1.91 5.01e-03 GO:0000122 negative regulation of transcription from RNA polymerase II promoter
1.73 4.11e-03 GO:0010629 negative regulation of gene expression
1.72 4.14e-03 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
1.71 2.34e-02 GO:0045892 negative regulation of transcription, DNA-dependent
1.68 4.59e-02 GO:0051253 negative regulation of RNA metabolic process
1.66 9.64e-03 GO:0031327 negative regulation of cellular biosynthetic process
1.66 1.24e-02 GO:0010558 negative regulation of macromolecule biosynthetic process
1.62 2.15e-02 GO:0009890 negative regulation of biosynthetic process
1.38 9.45e-04 GO:0048523 negative regulation of cellular process
1.37 4.43e-04 GO:0048519 negative regulation of biological process
1.32 6.69e-03 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.31 3.63e-02 GO:0006355 regulation of transcription, DNA-dependent
1.30 2.18e-02 GO:0010556 regulation of macromolecule biosynthetic process
1.27 4.55e-02 GO:0031326 regulation of cellular biosynthetic process
1.24 1.10e-02 GO:0032502 developmental process
1.24 3.16e-02 GO:0007275 multicellular organismal development
1.15 4.76e-03 GO:0050789 regulation of biological process
1.15 1.02e-02 GO:0050794 regulation of cellular process
1.14 2.67e-03 GO:0065007 biological regulation

Gene overrepresentation in compartment category:

Showing 1 to 4 of 4 entries
enrichment   p-value GO term description
2.63 1.33e-02 GO:0005925 focal adhesion
2.53 1.69e-02 GO:0030055 cell-substrate junction
2.51 2.87e-02 GO:0005924 cell-substrate adherens junction
1.16 9.22e-03 GO:0005634 nucleus

Gene overrepresentation in function category:

Showing 1 to 2 of 2 entries
enrichment   p-value GO term description
1.13 1.21e-02 GO:0005515 protein binding
1.07 3.54e-02 GO:0005488 binding