Motif ID: SP1.p2

Z-value: 1.092


Transcription factors associated with SP1.p2:

Gene SymbolEntrez IDGene Name
SP1 6667 Sp1 transcription factor

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
SP1chr12_+_537744220.831.1e-02Click!


Activity profile for motif SP1.p2.

activity profile for motif SP1.p2


Sorted Z-values histogram for motif SP1.p2

Sorted Z-values for motif SP1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of SP1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr17_-_66453561 1.302 NM_017983
 WIPI1
WD repeat domain, phosphoinositide interacting 1
chr1_+_211432732 1.253 RCOR3
REST corepressor 3
chr20_+_62371218 1.210 SLC2A4RG
SLC2A4 regulator
chrX_-_1572648 1.132 NM_001173473
 ASMTL
acetylserotonin O-methyltransferase-like
chr1_+_211432726 1.109 RCOR3
REST corepressor 3
chr10_+_135192694 1.087 NM_152911
NM_207127
NM_207128
 PAOX


polyamine oxidase (exo-N4-amino)


chr17_+_79989485 1.086 NM_005052
 RAC3
ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
chrY_-_1522648 1.075 NM_001173473
 ASMTL
acetylserotonin O-methyltransferase-like
chrX_-_134232663 1.068 LINC00087
long intergenic non-protein coding RNA 87
chr19_-_2015628 1.014 NM_017797
 BTBD2
BTB (POZ) domain containing 2
chr9_+_130922471 0.961 NM_024112
 C9orf16
chromosome 9 open reading frame 16
chr17_-_43045612 0.954 NM_006688
 C1QL1
complement component 1, q subcomponent-like 1
chr12_-_124457099 0.954 NM_025140
 CCDC92
coiled-coil domain containing 92
chr21_+_47401644 0.941 NM_001848
 COL6A1
collagen, type VI, alpha 1
chr17_+_55333843 0.878 NM_138962
 MSI2
musashi homolog 2 (Drosophila)
chr10_+_134351272 0.862 NM_005539
 INPP5A
inositol polyphosphate-5-phosphatase, 40kDa
chr10_-_15210610 0.842 NM_004808
 NMT2
N-myristoyltransferase 2
chr16_+_1203240 0.839 NM_001005407
NM_021098
 CACNA1H

calcium channel, voltage-dependent, T type, alpha 1H subunit

chr20_+_62371109 0.820 NM_020062
 SLC2A4RG
SLC2A4 regulator
chrX_+_134555867 0.814 LINC00086
long intergenic non-protein coding RNA 86

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 129 entries
enrichment   p-value GO term description
1.72 2.10e-02 GO:0051403 stress-activated MAPK cascade
1.63 4.90e-02 GO:0051494 negative regulation of cytoskeleton organization
1.62 3.72e-02 GO:0034138 toll-like receptor 3 signaling pathway
1.48 1.74e-02 GO:0043254 regulation of protein complex assembly
1.42 8.62e-03 GO:0051493 regulation of cytoskeleton organization
1.42 4.33e-02 GO:0006184 GTP catabolic process
1.41 2.96e-04 GO:0048011 nerve growth factor receptor signaling pathway
1.41 3.93e-02 GO:0046039 GTP metabolic process
1.38 1.56e-03 GO:0051129 negative regulation of cellular component organization
1.35 3.90e-03 GO:0009166 nucleotide catabolic process
1.35 7.66e-03 GO:0006195 purine nucleotide catabolic process
1.34 8.53e-03 GO:0072523 purine-containing compound catabolic process
1.34 2.90e-02 GO:0009143 nucleoside triphosphate catabolic process
1.34 2.90e-02 GO:0009154 purine ribonucleotide catabolic process
1.34 3.00e-02 GO:0009261 ribonucleotide catabolic process
1.34 3.80e-02 GO:0009146 purine nucleoside triphosphate catabolic process
1.33 1.98e-04 GO:0016568 chromatin modification
1.33 5.28e-04 GO:0006281 DNA repair
1.32 1.45e-04 GO:0007264 small GTPase mediated signal transduction
1.31 3.15e-02 GO:0034655 nucleobase, nucleoside, nucleotide and nucleic acid catabolic process

Gene overrepresentation in compartment category:

Showing 1 to 20 of 33 entries
enrichment   p-value GO term description
1.54 4.50e-02 GO:0034399 nuclear periphery
1.34 2.40e-02 GO:0005819 spindle
1.27 1.86e-23 GO:0031981 nuclear lumen
1.27 5.94e-16 GO:0005654 nucleoplasm
1.26 1.20e-24 GO:0044428 nuclear part
1.26 2.48e-04 GO:0005730 nucleolus
1.25 3.12e-02 GO:0005815 microtubule organizing center
1.24 2.30e-22 GO:0070013 intracellular organelle lumen
1.24 2.03e-05 GO:0015630 microtubule cytoskeleton
1.24 2.74e-04 GO:0005694 chromosome
1.23 3.80e-21 GO:0043233 organelle lumen
1.23 4.40e-21 GO:0031974 membrane-enclosed lumen
1.23 3.23e-18 GO:0005829 cytosol
1.21 3.96e-04 GO:0044451 nucleoplasm part
1.17 4.07e-38 GO:0005634 nucleus
1.15 1.53e-02 GO:0005794 Golgi apparatus
1.14 2.60e-09 GO:0043228 non-membrane-bounded organelle
1.14 2.60e-09 GO:0043232 intracellular non-membrane-bounded organelle
1.13 1.68e-48 GO:0043227 membrane-bounded organelle
1.13 1.06e-47 GO:0043231 intracellular membrane-bounded organelle

Gene overrepresentation in function category:

Showing 1 to 20 of 34 entries
enrichment   p-value GO term description
1.51 4.92e-02 GO:0008135 translation factor activity, nucleic acid binding
1.40 7.92e-03 GO:0005085 guanyl-nucleotide exchange factor activity
1.36 4.17e-03 GO:0003924 GTPase activity
1.30 3.14e-04 GO:0005525 GTP binding
1.28 2.31e-03 GO:0019001 guanyl nucleotide binding
1.28 2.31e-03 GO:0032561 guanyl ribonucleotide binding
1.28 8.34e-03 GO:0003779 actin binding
1.25 1.80e-06 GO:0019899 enzyme binding
1.25 4.40e-04 GO:0008092 cytoskeletal protein binding
1.25 3.13e-03 GO:0030695 GTPase regulator activity
1.24 9.49e-03 GO:0004674 protein serine/threonine kinase activity
1.22 1.87e-02 GO:0060589 nucleoside-triphosphatase regulator activity
1.21 2.19e-04 GO:0016301 kinase activity
1.20 9.33e-05 GO:0016772 transferase activity, transferring phosphorus-containing groups
1.20 5.34e-04 GO:0003723 RNA binding
1.20 2.10e-03 GO:0016773 phosphotransferase activity, alcohol group as acceptor
1.19 7.04e-14 GO:0000166 nucleotide binding
1.18 2.12e-09 GO:0035639 purine ribonucleoside triphosphate binding
1.18 3.14e-09 GO:0032553 ribonucleotide binding
1.18 3.14e-09 GO:0032555 purine ribonucleotide binding