Motif ID: SPI1.p2

Z-value: 1.578


Transcription factors associated with SPI1.p2:

Gene SymbolEntrez IDGene Name
SPI1 6688 spleen focus forming virus (SFFV) proviral integration oncogene spi1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
SPI1chr11_-_474000960.265.4e-01Click!


Activity profile for motif SPI1.p2.

activity profile for motif SPI1.p2


Sorted Z-values histogram for motif SPI1.p2

Sorted Z-values for motif SPI1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of SPI1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr9_-_107690526 1.025 NM_005502
ABCA1
ATP-binding cassette, sub-family A (ABC1), member 1
chr15_+_41136622 1.012 NM_001032367
SPINT1
serine peptidase inhibitor, Kunitz type 1
chr18_+_21452981 1.008 NM_000227
NM_001127718
LAMA3

laminin, alpha 3

chr14_-_61747956 0.919 TMEM30B
transmembrane protein 30B
chr3_-_10547221 0.848 ATP2B2
ATPase, Ca++ transporting, plasma membrane 2
chr4_-_84256012 0.788 NM_001098540
HPSE
heparanase
chr7_+_69064316 0.745 AUTS2
autism susceptibility candidate 2
chr4_-_15939949 0.733 FGFBP1
fibroblast growth factor binding protein 1
chr1_-_242687997 0.717 NM_152666
PLD5
phospholipase D family, member 5
chr19_-_51504799 0.670 NM_007196
NM_144505
NM_144506
NM_144507
KLK8



kallikrein-related peptidase 8



chr2_-_70780621 0.669 TGFA
transforming growth factor, alpha
chr7_-_98030165 0.661 BAIAP2L1
BAI1-associated protein 2-like 1
chr19_-_291335 0.652 NM_003712
NM_177526
PPAP2C

phosphatidic acid phosphatase type 2C

chr19_-_36004553 0.651 NM_001126056
NM_001126057
NM_001126058
NM_001190347
NM_001190348
NM_001190349
NM_033317
DMKN






dermokine






chr14_-_99737821 0.641 NM_022898
NM_138576
BCL11B

B-cell CLL/lymphoma 11B (zinc finger protein)

chr10_-_99161013 0.639 NM_001145114
NM_015179
RRP12

ribosomal RNA processing 12 homolog (S. cerevisiae)

chr10_-_135090325 0.637 NM_001109
NM_001164489
NM_001164490
ADAM8


ADAM metallopeptidase domain 8


chr1_-_153363544 0.635 NM_002964
S100A8
S100 calcium binding protein A8
chr8_-_15095791 0.633 NM_139167
SGCZ
sarcoglycan, zeta
chr1_-_159915382 0.625 NM_001135050
NM_020789
IGSF9

immunoglobulin superfamily, member 9

chr11_+_1861431 0.620 NM_001145841
TNNI2
troponin I type 2 (skeletal, fast)
chr1_+_186798031 0.614 NM_024420
PLA2G4A
phospholipase A2, group IVA (cytosolic, calcium-dependent)
chr6_+_43738757 0.614 VEGFA
vascular endothelial growth factor A
chr12_+_107712151 0.610 NM_001018072
BTBD11
BTB (POZ) domain containing 11
chr12_+_13044352 0.599 GPRC5A
G protein-coupled receptor, family C, group 5, member A
chr14_-_38064440 0.596 NM_004496
FOXA1
forkhead box A1
chr8_+_95653272 0.589 ESRP1
epithelial splicing regulatory protein 1
chr12_-_28122884 0.585 NM_198964
NM_198966
PTHLH

parathyroid hormone-like hormone

chr4_+_79472851 0.584 ANXA3
annexin A3
chr3_+_130612806 0.582 NM_001199179
NM_001001485
NM_001199183
NM_001199184
NM_001199185
NM_014382
NM_001001486
NM_001001487
ATP2C1







ATPase, Ca++ transporting, type 2C, member 1







chr12_+_41086189 0.575 NM_001843
NM_175038
CNTN1

contactin 1

chr7_-_100860991 0.562 NM_001084
PLOD3
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3
chr11_-_18270167 0.556 NM_001199744
NM_001127380
NM_030754
SAA2-SAA4
SAA2

SAA2-SAA4 readthrough
serum amyloid A2

chr4_-_84255999 0.538 HPSE
heparanase
chr4_-_84255895 0.536 NM_001199830
HPSE
heparanase
chr11_+_18287807 0.534 NM_000331
NM_001178006
NM_199161
SAA1


serum amyloid A1


chr4_+_84457256 0.531 AGPAT9
1-acylglycerol-3-phosphate O-acyltransferase 9
chr15_+_90744506 0.527 NM_198925
SEMA4B
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B
chr17_-_29641087 0.524 EVI2B
ecotropic viral integration site 2B
chr4_+_79472741 0.522 NM_005139
ANXA3
annexin A3
chr2_+_206547352 0.508 NRP2
neuropilin 2
chr17_-_7166505 0.507 NM_001185022
CLDN7
claudin 7
chr7_-_100860865 0.504 PLOD3
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3
chr6_-_136847078 0.503 NM_001198608
NM_001198609
NM_001198611
MAP7


microtubule-associated protein 7


chr11_+_34642587 0.503 NM_001206615
NM_012153
EHF

ets homologous factor

chr1_-_153588789 0.501 NM_020672
S100A14
S100 calcium binding protein A14
chr5_+_149737296 0.499 TCOF1
Treacher Collins-Franceschetti syndrome 1
chrX_-_135056132 0.499 NM_173470
MMGT1
membrane magnesium transporter 1
chr17_-_29641094 0.497 NM_006495
EVI2B
ecotropic viral integration site 2B
chr16_+_68771214 0.497 CDH1
cadherin 1, type 1, E-cadherin (epithelial)
chr17_+_54671059 0.496 NM_005450
NOG
noggin
chr7_-_100860841 0.495 PLOD3
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3
chr12_-_123466195 0.484 ABCB9
ATP-binding cassette, sub-family B (MDR/TAP), member 9
chr19_+_35739838 0.482 LSR
lipolysis stimulated lipoprotein receptor
chr10_-_105845556 0.480 COL17A1
collagen, type XVII, alpha 1
chr20_-_22565050 0.477 NM_021784
FOXA2
forkhead box A2
chr1_+_116916029 0.476 ATP1A1
ATPase, Na+/K+ transporting, alpha 1 polypeptide
chr11_-_118135197 0.469 NM_005797
NM_144765
MPZL2

myelin protein zero-like 2

chr19_+_50094911 0.468 NM_020719
PRR12
proline rich 12
chr10_-_99160987 0.461 RRP12
ribosomal RNA processing 12 homolog (S. cerevisiae)
chr17_-_39675078 0.458 NM_002275
KRT15
keratin 15
chr1_-_147245483 0.458 NM_005266
GJA5
gap junction protein, alpha 5, 40kDa
chr17_+_48610077 0.458 EPN3
epsin 3
chr11_-_118134986 0.455 MPZL2
myelin protein zero-like 2
chr10_-_105845619 0.442 NM_000494
COL17A1
collagen, type XVII, alpha 1
chr5_+_149737201 0.434 NM_000356
NM_001008657
NM_001135243
NM_001135244
NM_001135245
NM_001195141
TCOF1





Treacher Collins-Franceschetti syndrome 1





chr14_-_35344450 0.428 BAZ1A
bromodomain adjacent to zinc finger domain, 1A
chr12_+_56732658 0.427 NM_016584
IL23A
interleukin 23, alpha subunit p19
chr19_-_51456159 0.426 NM_001077491
NM_001077492
NM_012427
KLK5


kallikrein-related peptidase 5


chr19_+_35739778 0.423 LSR
lipolysis stimulated lipoprotein receptor
chr17_-_41322211 0.422 BRCA1
breast cancer 1, early onset
chr20_-_22564893 0.421 FOXA2
forkhead box A2
chr14_-_35344080 0.418 BAZ1A
bromodomain adjacent to zinc finger domain, 1A
chr8_+_75896707 0.417 NM_031461
CRISPLD1
cysteine-rich secretory protein LCCL domain containing 1
chr19_+_35739282 0.417 LSR
lipolysis stimulated lipoprotein receptor
chr20_-_3218834 0.417 NM_001174090
SLC4A11
solute carrier family 4, sodium borate transporter, member 11
chr12_+_110719143 0.416 ATP2A2
ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
chr2_-_31361284 0.415 GALNT14
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 14 (GalNAc-T14)
chr6_+_33589045 0.412 NM_002224
ITPR3
inositol 1,4,5-trisphosphate receptor, type 3
chr3_+_140770412 0.409 SPSB4
splA/ryanodine receptor domain and SOCS box containing 4
chr19_-_51472003 0.408 NM_001012964
NM_001012965
KLK6

kallikrein-related peptidase 6

chr2_-_113542970 0.407 NM_000575
IL1A
interleukin 1, alpha
chr3_-_116164321 0.404 LSAMP
limbic system-associated membrane protein
chr9_-_107690336 0.401 ABCA1
ATP-binding cassette, sub-family A (ABC1), member 1
chr7_+_69063768 0.398 NM_001127231
NM_001127232
NM_015570
AUTS2


autism susceptibility candidate 2


chr7_-_100860719 0.398 PLOD3
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3
chr3_+_31574431 0.398 STT3B
STT3, subunit of the oligosaccharyltransferase complex, homolog B (S. cerevisiae)
chr11_-_112034671 0.397 NM_001243211
NM_001562
IL18

interleukin 18 (interferon-gamma-inducing factor)

chrX_+_100075347 0.397 NM_001325
CSTF2
cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa
chr20_+_58179601 0.395 NM_080672
PHACTR3
phosphatase and actin regulator 3
chr12_+_101188373 0.390 NM_178826
ANO4
anoctamin 4
chr14_+_96671015 0.389 NM_000623
BDKRB2
bradykinin receptor B2
chr14_-_61748510 0.388 NM_001017970
TMEM30B
transmembrane protein 30B
chr5_-_140013285 0.386 NM_001040021
NM_001174104
NM_001174105
CD14


CD14 molecule


chr20_-_23030141 0.386 NM_000361
THBD
thrombomodulin
chr11_+_130029773 0.386 ST14
suppression of tumorigenicity 14 (colon carcinoma)
chr5_-_140013034 0.372 NM_000591
CD14
CD14 molecule
chr6_-_136847609 0.372 MAP7
microtubule-associated protein 7
chr7_+_18126543 0.371 NM_001204144
HDAC9
histone deacetylase 9
chr14_-_23288912 0.361 NM_001126106
SLC7A7
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr14_-_35344526 0.357 BAZ1A
bromodomain adjacent to zinc finger domain, 1A
chrX_+_128872924 0.356 NM_003399
XPNPEP2
X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound
chr7_-_100860615 0.356 PLOD3
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3
chrX_+_48367346 0.354 NM_022825
NM_203473
PORCN

porcupine homolog (Drosophila)

chr5_-_140998480 0.352 DIAPH1
diaphanous homolog 1 (Drosophila)
chrX_-_153236621 0.350 NM_005334
HCFC1
host cell factor C1 (VP16-accessory protein)
chr6_-_79787939 0.350 NM_017934
PHIP
pleckstrin homology domain interacting protein
chr1_-_12677347 0.348 NM_004753
DHRS3
dehydrogenase/reductase (SDR family) member 3
chr11_+_33563772 0.348 NM_012194
C11orf41
chromosome 11 open reading frame 41
chr17_+_45727274 0.346 NM_002265
KPNB1
karyopherin (importin) beta 1
chr2_+_206547131 0.346 NM_003872
NM_018534
NM_201264
NM_201266
NM_201267
NM_201279
NRP2





neuropilin 2





chr13_+_113623496 0.343 NM_001112732
MCF2L
MCF.2 cell line derived transforming sequence-like
chr19_+_35739519 0.341 NM_015925
NM_205834
NM_205835
LSR


lipolysis stimulated lipoprotein receptor


chr1_+_116916488 0.341 NM_001160233
ATP1A1
ATPase, Na+/K+ transporting, alpha 1 polypeptide
chr19_+_11071719 0.341 SMARCA4
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
chr19_+_15726028 0.340 NM_007253
CYP4F8
cytochrome P450, family 4, subfamily F, polypeptide 8
chr19_+_11071713 0.334 SMARCA4
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
chr1_-_184943673 0.333 NM_052966
FAM129A
family with sequence similarity 129, member A
chr14_-_35344490 0.331 BAZ1A
bromodomain adjacent to zinc finger domain, 1A
chr1_-_197115566 0.331 NM_001206846
NM_018136
ASPM

asp (abnormal spindle) homolog, microcephaly associated (Drosophila)

chr17_-_74497406 0.331 NM_024599
RHBDF2
rhomboid 5 homolog 2 (Drosophila)
chr20_-_6103860 0.331 FERMT1
fermitin family member 1
chr12_+_66218879 0.330 HMGA2
high mobility group AT-hook 2
chr22_+_26825220 0.326 NM_020437
ASPHD2
aspartate beta-hydroxylase domain containing 2
chr1_+_234040547 0.324 NM_173508
SLC35F3
solute carrier family 35, member F3
chr8_+_56792392 0.324 LYN
v-yes-1 Yamaguchi sarcoma viral related oncogene homolog
chr8_+_56792345 0.322 NM_001111097
NM_002350
LYN

v-yes-1 Yamaguchi sarcoma viral related oncogene homolog

chr1_+_11796211 0.321 AGTRAP
angiotensin II receptor-associated protein
chr8_-_144810691 0.320 FAM83H
family with sequence similarity 83, member H
chr14_-_38064176 0.319 FOXA1
forkhead box A1
chr18_+_8609670 0.316


chr1_+_11796177 0.315 AGTRAP
angiotensin II receptor-associated protein
chr10_+_105156430 0.315 PDCD11
programmed cell death 11
chr2_+_182321933 0.314 ITGA4
integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
chrX_-_40594663 0.314 MED14
mediator complex subunit 14
chr15_+_75074714 0.314 CSK
c-src tyrosine kinase
chr1_+_156252725 0.312 TMEM79
transmembrane protein 79
chr12_+_104850762 0.312 CHST11
carbohydrate (chondroitin 4) sulfotransferase 11
chr1_+_32050510 0.312 TINAGL1
tubulointerstitial nephritis antigen-like 1
chr12_+_104850784 0.311 CHST11
carbohydrate (chondroitin 4) sulfotransferase 11
chr5_+_140186658 0.310 NM_018907
NM_031500
PCDHA4

protocadherin alpha 4

chr12_-_6740814 0.310 NM_001142961
LPAR5
lysophosphatidic acid receptor 5
chr15_+_69606741 0.308 NM_001104554
PAQR5
progestin and adipoQ receptor family member V
chrX_-_14891156 0.308 NM_001018113
NM_152633
FANCB

Fanconi anemia, complementation group B

chr10_+_105156382 0.307 NM_014976
PDCD11
programmed cell death 11
chr12_-_72666305 0.307 LOC283392
uncharacterized LOC283392
chr17_-_56160564 0.306


chr5_+_131409484 0.306 NM_000758
CSF2
colony stimulating factor 2 (granulocyte-macrophage)
chr10_+_37414784 0.305 NM_052997
ANKRD30A
ankyrin repeat domain 30A
chr5_+_34915781 0.304 NM_018321
BRIX1
BRX1, biogenesis of ribosomes, homolog (S. cerevisiae)
chrX_+_73641084 0.303 NM_006517
SLC16A2
solute carrier family 16, member 2 (monocarboxylic acid transporter 8)
chr1_+_43766565 0.299 NM_001253357
NM_005424
TIE1

tyrosine kinase with immunoglobulin-like and EGF-like domains 1

chr19_+_11071792 0.298 NM_001128849
SMARCA4
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
chr17_-_7166263 0.298 NM_001185023
NM_001307
CLDN7

claudin 7

chr14_-_23285011 0.298 NM_001126105
SLC7A7
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr7_+_150148078 0.297 GIMAP8
GTPase, IMAP family member 8
chr8_-_10587942 0.296 NM_031439
SOX7
SRY (sex determining region Y)-box 7
chr17_-_7165788 0.296 CLDN7
claudin 7
chr4_-_37687932 0.295 NM_001085399
NM_001085400
RELL1

RELT-like 1

chr1_-_183560010 0.294 NM_001127651
NCF2
neutrophil cytosolic factor 2
chr17_-_27467395 0.293 MYO18A
myosin XVIIIA
chr20_+_58296264 0.292 NM_183244
NM_183246
PHACTR3

phosphatase and actin regulator 3

chr14_-_54421269 0.292 NM_130851
BMP4
bone morphogenetic protein 4
chr17_+_34431219 0.291 NM_002984
CCL4
chemokine (C-C motif) ligand 4
chr17_+_45727303 0.291 KPNB1
karyopherin (importin) beta 1
chr20_-_3218345 0.291 NM_032034
SLC4A11
solute carrier family 4, sodium borate transporter, member 11
chr6_-_47009992 0.291 NM_025048
NM_153840
GPR110

G protein-coupled receptor 110

chr1_-_161015688 0.289 USF1
upstream transcription factor 1
chr15_+_75074417 0.289 NM_001127190
NM_004383
CSK

c-src tyrosine kinase

chr19_+_4402658 0.288 NM_005483
CHAF1A
chromatin assembly factor 1, subunit A (p150)
chr17_+_65373574 0.287 PITPNC1
phosphatidylinositol transfer protein, cytoplasmic 1
chr1_-_246729546 0.287 NM_022366
TFB2M
transcription factor B2, mitochondrial
chr19_+_35645614 0.287 NM_014164
FXYD5
FXYD domain containing ion transport regulator 5
chr1_-_27481400 0.287 NM_003047
SLC9A1
solute carrier family 9 (sodium/hydrogen exchanger), member 1
chr9_+_2622134 0.286 VLDLR
very low density lipoprotein receptor
chr2_+_73612821 0.285 NM_015120
ALMS1
Alstrom syndrome 1
chr2_-_26101329 0.284 ASXL2
additional sex combs like 2 (Drosophila)
chr11_+_130029663 0.284 NM_021978
ST14
suppression of tumorigenicity 14 (colon carcinoma)
chr8_+_56792399 0.283 LYN
v-yes-1 Yamaguchi sarcoma viral related oncogene homolog
chrX_+_48542193 0.282 WAS
Wiskott-Aldrich syndrome (eczema-thrombocytopenia)
chr6_-_136847743 0.281 NM_001198614
NM_001198618
NM_001198619
MAP7


microtubule-associated protein 7


chr8_-_67579377 0.278 VCPIP1
valosin containing protein (p97)/p47 complex interacting protein 1
chr1_-_183559669 0.278 NM_000433
NM_001190789
NM_001190794
NCF2


neutrophil cytosolic factor 2


chrX_+_135067634 0.276 SLC9A6
solute carrier family 9 (sodium/hydrogen exchanger), member 6
chr12_+_72666462 0.276 NM_013381
TRHDE
thyrotropin-releasing hormone degrading enzyme
chr22_+_38453478 0.276 PICK1
protein interacting with PRKCA 1
chr15_+_90544608 0.275 NM_198526
ZNF710
zinc finger protein 710
chr6_-_108279307 0.274 SEC63
SEC63 homolog (S. cerevisiae)
chr6_+_7107986 0.273 NM_001003698
NM_001003699
NM_001003700
RREB1


ras responsive element binding protein 1


chrX_+_100075383 0.273 CSTF2
cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa
chr11_+_34642651 0.271 EHF
ets homologous factor
chr1_-_161015752 0.270 NM_007122
NM_207005
USF1

upstream transcription factor 1

chr1_-_57888785 0.270 DAB1
disabled homolog 1 (Drosophila)
chr19_-_51472816 0.269 NM_002774
KLK6
kallikrein-related peptidase 6
chr4_-_84256304 0.268 NM_001166498
NM_006665
HPSE

heparanase

chr19_-_15090349 0.268 SLC1A6
solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6
chr6_+_160148485 0.268 WTAP
Wilms tumor 1 associated protein
chr6_+_12290528 0.267 NM_001168319
NM_001955
EDN1

endothelin 1

chr9_-_74383301 0.267 NM_001135820
NM_013390
TMEM2

transmembrane protein 2

chr19_+_3185965 0.266 NCLN
nicalin

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.10 2.06e-20 GO:0009987 cellular process
1.17 4.62e-11 GO:0044260 cellular macromolecule metabolic process
1.11 7.05e-11 GO:0065007 biological regulation
1.15 2.22e-09 GO:0043170 macromolecule metabolic process
1.10 2.61e-08 GO:0050789 regulation of biological process
1.17 8.90e-08 GO:0071840 cellular component organization or biogenesis
1.11 5.16e-07 GO:0044238 primary metabolic process
1.17 5.83e-07 GO:0016043 cellular component organization
1.10 1.04e-06 GO:0050794 regulation of cellular process
1.18 3.88e-06 GO:0048518 positive regulation of biological process
1.14 1.07e-05 GO:0051716 cellular response to stimulus
1.10 1.23e-05 GO:0044237 cellular metabolic process
1.17 1.42e-05 GO:0071841 cellular component organization or biogenesis at cellular level
1.37 2.26e-05 GO:0045595 regulation of cell differentiation
1.31 2.51e-05 GO:0009611 response to wounding
1.21 3.65e-05 GO:0048583 regulation of response to stimulus
1.26 5.49e-05 GO:0002376 immune system process
1.18 5.94e-05 GO:0048519 negative regulation of biological process
1.17 6.68e-05 GO:0071842 cellular component organization at cellular level
1.22 7.85e-05 GO:0023051 regulation of signaling
1.20 8.00e-05 GO:0043412 macromolecule modification
1.28 1.15e-04 GO:0010646 regulation of cell communication
1.19 1.26e-04 GO:0065008 regulation of biological quality
1.16 1.32e-04 GO:0048731 system development
1.17 1.38e-04 GO:0048522 positive regulation of cellular process
1.24 1.40e-04 GO:0009966 regulation of signal transduction
1.37 1.55e-04 GO:0042060 wound healing
1.20 1.57e-04 GO:0006464 protein modification process
1.19 1.82e-04 GO:0048869 cellular developmental process
1.13 2.15e-04 GO:0023052 signaling
1.19 2.17e-04 GO:0030154 cell differentiation
1.29 3.78e-04 GO:0050793 regulation of developmental process
1.23 6.57e-04 GO:0051239 regulation of multicellular organismal process
1.13 6.66e-04 GO:0032502 developmental process
1.14 9.04e-04 GO:0048856 anatomical structure development
1.08 9.93e-04 GO:0008152 metabolic process
1.13 9.93e-04 GO:0007275 multicellular organismal development
1.38 1.04e-03 GO:0009967 positive regulation of signal transduction
1.20 1.13e-03 GO:0006996 organelle organization
1.29 1.27e-03 GO:0048584 positive regulation of response to stimulus
1.17 1.43e-03 GO:0048523 negative regulation of cellular process
1.21 1.52e-03 GO:0009653 anatomical structure morphogenesis
1.37 2.03e-03 GO:0001775 cell activation
1.32 2.16e-03 GO:0010628 positive regulation of gene expression
1.66 2.31e-03 GO:0050900 leukocyte migration
1.35 3.95e-03 GO:0010647 positive regulation of cell communication
1.29 3.97e-03 GO:2000026 regulation of multicellular organismal development
1.27 4.38e-03 GO:0031328 positive regulation of cellular biosynthetic process
1.16 4.39e-03 GO:0090304 nucleic acid metabolic process
1.13 4.74e-03 GO:0007165 signal transduction
1.20 4.85e-03 GO:0007399 nervous system development
1.27 5.03e-03 GO:0009891 positive regulation of biosynthetic process
1.79 6.27e-03 GO:0040029 regulation of gene expression, epigenetic
1.34 6.47e-03 GO:0023056 positive regulation of signaling
1.26 6.52e-03 GO:0048468 cell development
1.35 8.57e-03 GO:0007596 blood coagulation
1.35 8.57e-03 GO:0050817 coagulation
1.35 8.73e-03 GO:0007599 hemostasis
1.37 8.97e-03 GO:0051094 positive regulation of developmental process
1.28 1.31e-02 GO:0010557 positive regulation of macromolecule biosynthetic process
1.15 1.40e-02 GO:0006950 response to stress
1.22 1.76e-02 GO:0010604 positive regulation of macromolecule metabolic process
1.58 1.90e-02 GO:0030155 regulation of cell adhesion
1.41 1.94e-02 GO:0045597 positive regulation of cell differentiation
1.20 2.65e-02 GO:0009893 positive regulation of metabolic process
1.23 2.83e-02 GO:0009605 response to external stimulus
1.28 3.13e-02 GO:0009790 embryo development
1.20 3.18e-02 GO:0051641 cellular localization
1.24 3.59e-02 GO:0040011 locomotion
1.43 3.63e-02 GO:0051270 regulation of cellular component movement
1.29 3.69e-02 GO:0051276 chromosome organization
1.36 3.79e-02 GO:0016477 cell migration
1.23 4.01e-02 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.14 4.12e-02 GO:0044267 cellular protein metabolic process
1.16 4.27e-02 GO:0007166 cell surface receptor linked signaling pathway
1.16 4.81e-02 GO:0010467 gene expression
1.23 4.85e-02 GO:0022008 neurogenesis

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.29 5.28e-13 GO:0031981 nuclear lumen
1.27 5.89e-13 GO:0044428 nuclear part
1.24 2.75e-11 GO:0043233 organelle lumen
1.24 6.34e-11 GO:0070013 intracellular organelle lumen
1.23 9.83e-11 GO:0031974 membrane-enclosed lumen
1.13 2.99e-10 GO:0044422 organelle part
1.13 6.34e-10 GO:0044446 intracellular organelle part
1.30 6.10e-09 GO:0005654 nucleoplasm
1.26 1.35e-08 GO:0012505 endomembrane system
1.36 3.96e-07 GO:0044432 endoplasmic reticulum part
1.20 4.66e-07 GO:0044459 plasma membrane part
1.03 3.29e-06 GO:0005623 cell
1.36 3.84e-06 GO:0005789 endoplasmic reticulum membrane
1.03 4.09e-06 GO:0044464 cell part
1.28 4.09e-06 GO:0005783 endoplasmic reticulum
1.35 6.90e-06 GO:0042175 nuclear membrane-endoplasmic reticulum network
1.05 1.25e-05 GO:0044424 intracellular part
1.08 2.88e-05 GO:0016020 membrane
1.26 1.14e-04 GO:0005794 Golgi apparatus
1.23 1.20e-04 GO:0005887 integral to plasma membrane
1.05 1.29e-04 GO:0005622 intracellular
1.38 1.48e-04 GO:0000139 Golgi membrane
1.22 2.52e-04 GO:0031226 intrinsic to plasma membrane
1.07 4.80e-04 GO:0005737 cytoplasm
1.14 4.85e-04 GO:0043234 protein complex
1.27 5.04e-04 GO:0005626 insoluble fraction
1.32 5.33e-04 GO:0044431 Golgi apparatus part
1.29 8.67e-04 GO:0044451 nucleoplasm part
1.08 9.52e-04 GO:0044425 membrane part
1.06 1.50e-03 GO:0043227 membrane-bounded organelle
1.26 2.00e-03 GO:0005624 membrane fraction
1.06 2.17e-03 GO:0043231 intracellular membrane-bounded organelle
1.32 3.16e-03 GO:0005730 nucleolus
1.05 5.59e-03 GO:0043226 organelle
1.15 7.45e-03 GO:0031090 organelle membrane
1.05 1.07e-02 GO:0043229 intracellular organelle
1.10 1.41e-02 GO:0032991 macromolecular complex
1.34 1.46e-02 GO:0043005 neuron projection
1.08 2.07e-02 GO:0005634 nucleus
1.08 3.52e-02 GO:0031224 intrinsic to membrane
1.08 4.20e-02 GO:0016021 integral to membrane
1.27 4.82e-02 GO:0005694 chromosome

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.15 6.03e-22 GO:0005515 protein binding
1.07 1.93e-14 GO:0005488 binding
1.58 2.36e-04 GO:0000975 regulatory region DNA binding
1.58 2.36e-04 GO:0001067 regulatory region nucleic acid binding
1.58 2.36e-04 GO:0044212 transcription regulatory region DNA binding
1.58 4.92e-04 GO:0010843 promoter binding
1.46 5.55e-04 GO:0016564 transcription repressor activity
1.19 1.14e-03 GO:0032559 adenyl ribonucleotide binding
1.19 2.39e-03 GO:0030554 adenyl nucleotide binding
1.19 2.63e-03 GO:0005524 ATP binding
1.29 2.66e-03 GO:0043565 sequence-specific DNA binding
1.42 3.05e-03 GO:0016563 transcription activator activity
1.65 3.29e-03 GO:0003690 double-stranded DNA binding
2.19 6.13e-03 GO:0003823 antigen binding
1.29 9.26e-03 GO:0004672 protein kinase activity
1.22 9.80e-03 GO:0030528 transcription regulator activity
1.51 1.38e-02 GO:0043566 structure-specific DNA binding
1.14 1.49e-02 GO:0000166 nucleotide binding