Motif ID: SPI1.p2

Z-value: 1.578


Transcription factors associated with SPI1.p2:

Gene SymbolEntrez IDGene Name
SPI1 6688 spleen focus forming virus (SFFV) proviral integration oncogene spi1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
SPI1chr11_-_474000960.265.4e-01Click!


Activity profile for motif SPI1.p2.

activity profile for motif SPI1.p2


Sorted Z-values histogram for motif SPI1.p2

Sorted Z-values for motif SPI1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of SPI1.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr9_-_107690526 1.025 NM_005502
 ABCA1
ATP-binding cassette, sub-family A (ABC1), member 1
chr15_+_41136622 1.012 NM_001032367
 SPINT1
serine peptidase inhibitor, Kunitz type 1
chr18_+_21452981 1.008 NM_000227
NM_001127718
 LAMA3

laminin, alpha 3

chr14_-_61747956 0.919 TMEM30B
transmembrane protein 30B
chr3_-_10547221 0.848 ATP2B2
ATPase, Ca++ transporting, plasma membrane 2
chr4_-_84256012 0.788 NM_001098540
 HPSE
heparanase
chr7_+_69064316 0.745 AUTS2
autism susceptibility candidate 2
chr4_-_15939949 0.733 FGFBP1
fibroblast growth factor binding protein 1
chr1_-_242687997 0.717 NM_152666
 PLD5
phospholipase D family, member 5
chr19_-_51504799 0.670 NM_007196
NM_144505
NM_144506
NM_144507
 KLK8



kallikrein-related peptidase 8



chr2_-_70780621 0.669 TGFA
transforming growth factor, alpha
chr7_-_98030165 0.661 BAIAP2L1
BAI1-associated protein 2-like 1
chr19_-_291335 0.652 NM_003712
NM_177526
 PPAP2C

phosphatidic acid phosphatase type 2C

chr19_-_36004553 0.651 NM_001126056
NM_001126057
NM_001126058
NM_001190347
NM_001190348
NM_001190349
NM_033317
 DMKN






dermokine






chr14_-_99737821 0.641 NM_022898
NM_138576
 BCL11B

B-cell CLL/lymphoma 11B (zinc finger protein)

chr10_-_99161013 0.639 NM_001145114
NM_015179
 RRP12

ribosomal RNA processing 12 homolog (S. cerevisiae)

chr10_-_135090325 0.637 NM_001109
NM_001164489
NM_001164490
 ADAM8


ADAM metallopeptidase domain 8


chr1_-_153363544 0.635 NM_002964
 S100A8
S100 calcium binding protein A8
chr8_-_15095791 0.633 NM_139167
 SGCZ
sarcoglycan, zeta
chr1_-_159915382 0.625 NM_001135050
NM_020789
 IGSF9

immunoglobulin superfamily, member 9


Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 77 entries
enrichment   p-value GO term description
1.79 6.27e-03 GO:0040029 regulation of gene expression, epigenetic
1.66 2.31e-03 GO:0050900 leukocyte migration
1.58 1.90e-02 GO:0030155 regulation of cell adhesion
1.43 3.63e-02 GO:0051270 regulation of cellular component movement
1.41 1.94e-02 GO:0045597 positive regulation of cell differentiation
1.38 1.04e-03 GO:0009967 positive regulation of signal transduction
1.37 2.26e-05 GO:0045595 regulation of cell differentiation
1.37 1.55e-04 GO:0042060 wound healing
1.37 2.03e-03 GO:0001775 cell activation
1.37 8.97e-03 GO:0051094 positive regulation of developmental process
1.36 3.79e-02 GO:0016477 cell migration
1.35 3.95e-03 GO:0010647 positive regulation of cell communication
1.35 8.57e-03 GO:0007596 blood coagulation
1.35 8.57e-03 GO:0050817 coagulation
1.35 8.73e-03 GO:0007599 hemostasis
1.34 6.47e-03 GO:0023056 positive regulation of signaling
1.32 2.16e-03 GO:0010628 positive regulation of gene expression
1.31 2.51e-05 GO:0009611 response to wounding
1.29 3.78e-04 GO:0050793 regulation of developmental process
1.29 1.27e-03 GO:0048584 positive regulation of response to stimulus

Gene overrepresentation in compartment category:

Showing 1 to 20 of 42 entries
enrichment   p-value GO term description
1.38 1.48e-04 GO:0000139 Golgi membrane
1.36 3.96e-07 GO:0044432 endoplasmic reticulum part
1.36 3.84e-06 GO:0005789 endoplasmic reticulum membrane
1.35 6.90e-06 GO:0042175 nuclear membrane-endoplasmic reticulum network
1.34 1.46e-02 GO:0043005 neuron projection
1.32 5.33e-04 GO:0044431 Golgi apparatus part
1.32 3.16e-03 GO:0005730 nucleolus
1.30 6.10e-09 GO:0005654 nucleoplasm
1.29 5.28e-13 GO:0031981 nuclear lumen
1.29 8.67e-04 GO:0044451 nucleoplasm part
1.28 4.09e-06 GO:0005783 endoplasmic reticulum
1.27 5.89e-13 GO:0044428 nuclear part
1.27 5.04e-04 GO:0005626 insoluble fraction
1.27 4.82e-02 GO:0005694 chromosome
1.26 1.35e-08 GO:0012505 endomembrane system
1.26 1.14e-04 GO:0005794 Golgi apparatus
1.26 2.00e-03 GO:0005624 membrane fraction
1.24 2.75e-11 GO:0043233 organelle lumen
1.24 6.34e-11 GO:0070013 intracellular organelle lumen
1.23 9.83e-11 GO:0031974 membrane-enclosed lumen

Gene overrepresentation in function category:

Showing 1 to 18 of 18 entries
enrichment   p-value GO term description
2.19 6.13e-03 GO:0003823 antigen binding
1.65 3.29e-03 GO:0003690 double-stranded DNA binding
1.58 2.36e-04 GO:0000975 regulatory region DNA binding
1.58 2.36e-04 GO:0001067 regulatory region nucleic acid binding
1.58 2.36e-04 GO:0044212 transcription regulatory region DNA binding
1.58 4.92e-04 GO:0010843 promoter binding
1.51 1.38e-02 GO:0043566 structure-specific DNA binding
1.46 5.55e-04 GO:0016564 transcription repressor activity
1.42 3.05e-03 GO:0016563 transcription activator activity
1.29 2.66e-03 GO:0043565 sequence-specific DNA binding
1.29 9.26e-03 GO:0004672 protein kinase activity
1.22 9.80e-03 GO:0030528 transcription regulator activity
1.19 1.14e-03 GO:0032559 adenyl ribonucleotide binding
1.19 2.39e-03 GO:0030554 adenyl nucleotide binding
1.19 2.63e-03 GO:0005524 ATP binding
1.15 6.03e-22 GO:0005515 protein binding
1.14 1.49e-02 GO:0000166 nucleotide binding
1.07 1.93e-14 GO:0005488 binding