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Motif ID: SPIB.p2

Z-value: 0.962

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr1_-_207205996	0.871	NM_001083924 NM_023938	C1orf116	chromosome 1 open reading frame 116
chr12_+_4382882	0.641	NM_001759	CCND2	cyclin D2
chr2_+_113885137	0.626	NM_173842	IL1RN	interleukin 1 receptor antagonist
chr1_+_186798031	0.550	NM_024420	PLA2G4A	phospholipase A2, group IVA (cytosolic, calcium-dependent)
chr3_-_189840225	0.510	NM_001134418	LEPREL1	leprecan-like 1
chr2_+_113885145	0.508		IL1RN	interleukin 1 receptor antagonist
chr4_+_40198526	0.502	NM_004310	RHOH	ras homolog gene family, member H
chr6_-_47009992	0.484	NM_025048 NM_153840	GPR110	G protein-coupled receptor 110
chr18_-_53068755	0.452		TCF4	transcription factor 4
chr2_+_47596286	0.420	NM_002354	EPCAM	epithelial cell adhesion molecule
chr12_-_6745087	0.381	NM_020400	LPAR5	lysophosphatidic acid receptor 5
chr8_-_144810691	0.376		FAM83H	family with sequence similarity 83, member H
chr3_-_12800739	0.362	NM_018306	TMEM40	transmembrane protein 40
chr1_-_183560010	0.356	NM_001127651	NCF2	neutrophil cytosolic factor 2
chr1_-_161008710	0.350		TSTD1	thiosulfate sulfurtransferase (rhodanese)-like domain containing 1
chr1_-_161008733	0.336	NM_001113205 NM_001113206 NM_001113207	TSTD1 F11R	thiosulfate sulfurtransferase (rhodanese)-like domain containing 1 F11 receptor
chr19_-_49243836	0.322	NM_017805	RASIP1	Ras interacting protein 1
chr17_-_56492938	0.321		RNF43	ring finger protein 43
chr1_+_160370363	0.320	NM_020335	VANGL2	vang-like 2 (van gogh, Drosophila)
chr1_-_183559669	0.319	NM_000433 NM_001190789 NM_001190794	NCF2	neutrophil cytosolic factor 2
chr8_+_82644663	0.319	NM_152284	CHMP4C	charged multivesicular body protein 4C
chr18_-_47376156	0.317		MYO5B	myosin VB
chr12_-_8815370	0.315	NM_003480	MFAP5	microfibrillar associated protein 5
chr18_+_21452981	0.313	NM_000227 NM_001127718	LAMA3	laminin, alpha 3
chr1_-_201368716	0.313		LAD1	ladinin 1
chr6_+_28048481	0.306	NM_003447	ZNF165	zinc finger protein 165
chr6_+_116782555	0.303	NM_001010919	FAM26F	family with sequence similarity 26, member F
chr1_-_183559463	0.298		NCF2	neutrophil cytosolic factor 2
chr3_-_46718898	0.298	NM_182775	ALS2CL	ALS2 C-terminal like
chr19_+_54371170	0.297		MYADM	myeloid-associated differentiation marker
chr8_+_104512975	0.294	NM_001100117	RIMS2	regulating synaptic membrane exocytosis 2
chr14_-_22005035	0.287	NM_005407	SALL2	sal-like 2 (Drosophila)
chr6_-_136847078	0.279	NM_001198608 NM_001198609 NM_001198611	MAP7	microtubule-associated protein 7
chr6_-_41130820	0.278		TREM2	triggering receptor expressed on myeloid cells 2
chr8_-_22550708	0.275	NM_004430	EGR3	early growth response 3
chr19_-_51523272	0.271	NM_002776 NM_001077500	KLK10	kallikrein-related peptidase 10
chr2_-_31352489	0.268	NM_001253827	GALNT14	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 14 (GalNAc-T14)
chr6_-_41130864	0.268		TREM2	triggering receptor expressed on myeloid cells 2
chr1_+_24645811	0.268	NM_198173 NM_198174	GRHL3	grainyhead-like 3 (Drosophila)
chr1_+_200860619	0.267	NM_018265	C1orf106	chromosome 1 open reading frame 106
chr8_+_75736771	0.265	NM_015886	PI15	peptidase inhibitor 15
chr17_-_56494889	0.262		RNF43	ring finger protein 43
chr5_+_52776479	0.262		FST	follistatin
chr12_+_41831484	0.261	NM_013377	PDZRN4	PDZ domain containing ring finger 4
chr6_-_41130921	0.260	NM_018965	TREM2	triggering receptor expressed on myeloid cells 2
chr15_-_59665069	0.256	NM_004998	MYO1E	myosin IE
chr8_+_124194751	0.251	NM_032899 NM_207006	FAM83A	family with sequence similarity 83, member A
chr22_-_39639967	0.249		PDGFB	platelet-derived growth factor beta polypeptide
chr12_+_47610244	0.248		FAM113B	family with sequence similarity 113, member B
chr11_-_112034671	0.248	NM_001243211 NM_001562	IL18	interleukin 18 (interferon-gamma-inducing factor)
chr1_+_24645914	0.240	NM_001195010	GRHL3	grainyhead-like 3 (Drosophila)
chr16_+_57662301	0.239	NM_001145771 NM_001145772 NM_001145773 NM_201524 NM_201525	GPR56	G protein-coupled receptor 56
chr9_+_93589704	0.237	NM_001174167	SYK	spleen tyrosine kinase
chr2_-_69098502	0.233	NM_014482	BMP10	bone morphogenetic protein 10
chr4_+_77356252	0.232	NM_020859	SHROOM3	shroom family member 3
chr17_-_56494930	0.231	NM_017763	RNF43	ring finger protein 43
chr17_+_7942351	0.230	NM_001039130 NM_001039131 NM_001141	ALOX15B	arachidonate 15-lipoxygenase, type B
chr7_-_19184984	0.228	NM_152898	FERD3L	Fer3-like (Drosophila)
chr12_-_52886971	0.227	NM_005554	KRT6A	keratin 6A
chr19_+_35739282	0.226		LSR	lipolysis stimulated lipoprotein receptor
chr19_-_51522953	0.226	NM_145888	KLK10	kallikrein-related peptidase 10
chr9_-_23821477	0.225	NM_001171197	ELAVL2	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)
chr4_-_84255999	0.220		HPSE	heparanase
chr8_-_22550057	0.218	NM_001199881	EGR3	early growth response 3
chr2_-_113542970	0.216	NM_000575	IL1A	interleukin 1, alpha
chr15_+_41136178	0.216	NM_003710 NM_181642	SPINT1	serine peptidase inhibitor, Kunitz type 1
chr13_-_20805371	0.211	NM_006783	GJB6	gap junction protein, beta 6, 30kDa
chr4_-_36245893	0.209	NM_015230	ARAP2	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr2_-_161056762	0.204		ITGB6	integrin, beta 6
chr14_+_21510384	0.201	NM_032572	RNASE7	ribonuclease, RNase A family, 7
chr19_+_35739519	0.200	NM_015925 NM_205834 NM_205835	LSR	lipolysis stimulated lipoprotein receptor
chr4_-_84255895	0.199	NM_001199830	HPSE	heparanase
chr3_+_136537860	0.199	NM_001097599 NM_001097600 NM_025246	TMEM22	transmembrane protein 22
chr15_+_74833517	0.198	NM_006465	ARID3B	AT rich interactive domain 3B (BRIGHT-like)
chr4_-_25864430	0.195	NM_015187	SEL1L3	sel-1 suppressor of lin-12-like 3 (C. elegans)
chr17_+_67410825	0.195	NM_002758	MAP2K6	mitogen-activated protein kinase kinase 6
chr1_-_209825673	0.195	NM_001127641	LAMB3	laminin, beta 3
chr1_-_242612757	0.192	NM_001195811 NM_001195812	PLD5	phospholipase D family, member 5
chrX_-_51239426	0.191	NM_018159	NUDT11	nudix (nucleoside diphosphate linked moiety X)-type motif 11
chr6_+_47624222	0.190	NM_153839	GPR111	G protein-coupled receptor 111
chr20_+_58296264	0.189	NM_183244 NM_183246	PHACTR3	phosphatase and actin regulator 3
chr7_+_145813828	0.186		CNTNAP2	contactin associated protein-like 2
chr2_+_206547352	0.184		NRP2	neuropilin 2
chr4_-_84256012	0.184	NM_001098540	HPSE	heparanase
chr16_+_30194925	0.183		CORO1A	coronin, actin binding protein, 1A
chr12_-_54779482	0.183		ZNF385A	zinc finger protein 385A
chr1_+_13911966	0.182	NM_001006624 NM_001006625	PDPN	podoplanin
chrX_-_51239295	0.182		NUDT11	nudix (nucleoside diphosphate linked moiety X)-type motif 11
chr1_+_156030965	0.179	NM_020387	RAB25	RAB25, member RAS oncogene family
chr1_-_209825797	0.177	NM_000228	LAMB3	laminin, beta 3
chr11_+_57365026	0.177	NM_000062	SERPING1	serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
chr2_-_161056573	0.177	NM_000888	ITGB6	integrin, beta 6
chr19_+_54371125	0.175	NM_001020819 NM_138373	MYADM	myeloid-associated differentiation marker
chr1_+_156254069	0.175	NM_032323	TMEM79	transmembrane protein 79
chr2_-_46384	0.174	NM_001077710	FAM110C	family with sequence similarity 110, member C
chr18_+_32621299	0.173	NM_014268	MAPRE2	microtubule-associated protein, RP/EB family, member 2
chr17_-_27467395	0.173		MYO18A	myosin XVIIIA
chr2_+_96991934	0.173	NM_178495 NM_001163524	ITPRIPL1	inositol 1,4,5-trisphosphate receptor interacting protein-like 1
chr13_+_93879011	0.172	NM_005708	GPC6	glypican 6
chr11_-_118123001	0.172	NM_198275	MPZL3	myelin protein zero-like 3
chr4_+_103422730	0.171		NFKB1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
chr15_-_59665053	0.170		MYO1E	myosin IE
chr1_-_155948317	0.168	NM_001162383 NM_001162384	ARHGEF2	Rho/Rac guanine nucleotide exchange factor (GEF) 2
chr17_+_30814708	0.167
chr2_-_96811138	0.166	NM_004418	DUSP2	dual specificity phosphatase 2
chr15_-_72598655	0.166	NM_001172685	CELF6	CUGBP, Elav-like family member 6
chr1_-_25256364	0.164		RUNX3	runt-related transcription factor 3
chr11_-_118135197	0.163	NM_005797 NM_144765	MPZL2	myelin protein zero-like 2
chr4_+_103422822	0.160		NFKB1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
chr1_+_205473683	0.159	NM_002596 NM_212502 NM_212503	CDK18	cyclin-dependent kinase 18
chr19_-_36004553	0.159	NM_001126056 NM_001126057 NM_001126058 NM_001190347 NM_001190348 NM_001190349 NM_033317	DMKN	dermokine
chr2_-_74667553	0.159	NM_001015056 NM_033046	RTKN	rhotekin
chr7_+_145813452	0.158	NM_014141	CNTNAP2	contactin associated protein-like 2
chr12_+_47610051	0.158	NM_138371	FAM113B	family with sequence similarity 113, member B
chr18_-_28681885	0.158	NM_004949 NM_024422	DSC2	desmocollin 2
chr6_-_47253962	0.157		TNFRSF21	tumor necrosis factor receptor superfamily, member 21
chr11_+_66824285	0.157	NM_014578	RHOD	ras homolog gene family, member D
chr20_+_1874779	0.156	NM_001040022	SIRPA	signal-regulatory protein alpha
chr1_+_82266081	0.155	NM_012302	LPHN2	latrophilin 2
chr12_+_56732658	0.155	NM_016584	IL23A	interleukin 23, alpha subunit p19
chr11_+_65554504	0.155	NM_004561	OVOL1	ovo-like 1(Drosophila)
chr18_-_53177999	0.155	NM_001243231	TCF4	transcription factor 4
chr6_+_106534188	0.154	NM_001198	PRDM1	PR domain containing 1, with ZNF domain
chr1_-_201368617	0.154	NM_005558	LAD1	ladinin 1
chr3_-_151034514	0.154	NM_023915	GPR87	G protein-coupled receptor 87
chr11_-_118134986	0.152		MPZL2	myelin protein zero-like 2
chr12_-_52845862	0.152	NM_005555	KRT6B	keratin 6B
chr1_-_155948206	0.152		ARHGEF2	Rho/Rac guanine nucleotide exchange factor (GEF) 2
chr11_-_119999516	0.152		TRIM29	tripartite motif containing 29
chr1_+_183155393	0.152		LAMC2	laminin, gamma 2
chr6_-_136847743	0.151	NM_001198614 NM_001198618 NM_001198619	MAP7	microtubule-associated protein 7
chr19_-_51472003	0.151	NM_001012964 NM_001012965	KLK6	kallikrein-related peptidase 6
chr11_+_65554566	0.150		OVOL1	ovo-like 1(Drosophila)
chr7_-_36429695	0.150	NM_001100425	KIAA0895	KIAA0895
chr11_-_72385411	0.148	NM_002599	PDE2A	phosphodiesterase 2A, cGMP-stimulated
chr8_-_101734290	0.148		PABPC1	poly(A) binding protein, cytoplasmic 1
chr17_+_40439564	0.148	NM_003152	STAT5A	signal transducer and activator of transcription 5A
chr11_+_66824308	0.148		RHOD	ras homolog gene family, member D
chr12_-_31479120	0.147	NM_001135811 NM_021238 NM_001135812	FAM60A	family with sequence similarity 60, member A
chr9_-_131940481	0.147		IER5L	immediate early response 5-like
chr19_+_10381516	0.147	NM_000201	ICAM1	intercellular adhesion molecule 1
chr2_+_182321618	0.146	NM_000885	ITGA4	integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
chr2_+_233925104	0.146		INPP5D	inositol polyphosphate-5-phosphatase, 145kDa
chr12_-_31479084	0.145		FAM60A	family with sequence similarity 60, member A
chr6_+_84562984	0.145	NM_001009994	RIPPLY2	ripply2 homolog (zebrafish)
chr17_-_76124791	0.144	NM_001127198	TMC6	transmembrane channel-like 6
chr19_+_49838646	0.144		CD37	CD37 molecule
chr12_-_106533810	0.144	NM_014840	NUAK1	NUAK family, SNF1-like kinase, 1
chr2_-_85108238	0.143	NM_001080824	C2orf89	chromosome 2 open reading frame 89
chrX_-_117119282	0.143	NM_001168299	KLHL13	kelch-like 13 (Drosophila)
chr12_+_7060517	0.142		PTPN6	protein tyrosine phosphatase, non-receptor type 6
chr1_-_120935893	0.142		FCGR1B	Fc fragment of IgG, high affinity Ib, receptor (CD64)
chr21_+_30517897	0.141		C21orf7	chromosome 21 open reading frame 7
chr6_-_29012951	0.141	NM_030903	OR2W1	olfactory receptor, family 2, subfamily W, member 1
chr6_-_47254143	0.140		TNFRSF21	tumor necrosis factor receptor superfamily, member 21
chr19_+_49838673	0.140	NM_001040031 NM_001774	CD37	CD37 molecule
chr12_+_7060543	0.140		PTPN6	protein tyrosine phosphatase, non-receptor type 6
chr1_-_23886284	0.140	NM_002167	ID3	inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
chr1_-_24469571	0.139	NM_021258	IL22RA1	interleukin 22 receptor, alpha 1
chr2_+_233925035	0.139	NM_001017915 NM_005541	INPP5D	inositol polyphosphate-5-phosphatase, 145kDa
chr8_+_22437983	0.138	NM_176871 NM_198042	PDLIM2	PDZ and LIM domain 2 (mystique)
chrX_-_80065182	0.138	NM_153252	BRWD3	bromodomain and WD repeat domain containing 3
chr12_+_7060531	0.138		PTPN6	protein tyrosine phosphatase, non-receptor type 6
chr13_+_37005966	0.138	NM_001111046 NM_001111047	CCNA1	cyclin A1
chr12_-_8815266	0.137		MFAP5	microfibrillar associated protein 5
chr12_-_24103842	0.136		SOX5	SRY (sex determining region Y)-box 5
chr12_-_31479038	0.136		FAM60A	family with sequence similarity 60, member A
chr18_-_53303129	0.136	NM_001243226	TCF4	transcription factor 4
chr6_+_54711568	0.135	NM_001010872	FAM83B	family with sequence similarity 83, member B
chr18_-_53089722	0.135	NM_001243233	TCF4	transcription factor 4
chr3_-_58563490	0.135	NM_001076778 NM_007177	FAM107A	family with sequence similarity 107, member A
chr6_+_130758261	0.135	NM_052913	TMEM200A	transmembrane protein 200A
chr7_+_150147936	0.135	NM_175571	GIMAP8	GTPase, IMAP family member 8
chr5_-_158635080	0.134	NM_001199381	RNF145	ring finger protein 145
chr2_+_155555092	0.134	NM_002239	KCNJ3	potassium inwardly-rectifying channel, subfamily J, member 3
chr12_+_7060433	0.134	NM_002831 NM_080549	PTPN6	protein tyrosine phosphatase, non-receptor type 6
chr1_-_201368434	0.134		LAD1	ladinin 1
chr17_+_48610045	0.133	NM_017957	EPN3	epsin 3
chr7_+_37960418	0.133		EPDR1	ependymin related protein 1 (zebrafish)
chr17_-_7166263	0.133	NM_001185023 NM_001307	CLDN7	claudin 7
chr6_-_136847609	0.133		MAP7	microtubule-associated protein 7
chr17_+_7348362	0.132	NM_000747	CHRNB1	cholinergic receptor, nicotinic, beta 1 (muscle)
chr4_-_10023094	0.132	NM_020041	SLC2A9	solute carrier family 2 (facilitated glucose transporter), member 9
chr18_+_29598444	0.132	NM_017831	RNF125	ring finger protein 125
chr15_+_77287428	0.132	NM_003978	PSTPIP1	proline-serine-threonine phosphatase interacting protein 1
chr2_-_70780621	0.132		TGFA	transforming growth factor, alpha
chr8_-_57233240	0.132	NM_138969	SDR16C5	short chain dehydrogenase/reductase family 16C, member 5
chr7_+_150148078	0.131		GIMAP8	GTPase, IMAP family member 8
chr1_-_226926875	0.131	NM_002221	ITPKB	inositol-trisphosphate 3-kinase B
chrX_-_33357725	0.130	NM_000109	DMD	dystrophin
chr12_-_52867521	0.130	NM_173086	KRT6C	keratin 6C
chr21_+_43919741	0.130	NM_018964	SLC37A1	solute carrier family 37 (glycerol-3-phosphate transporter), member 1
chr5_+_35856990	0.129	NM_002185	IL7R	interleukin 7 receptor
chr18_-_52625278	0.129	NM_001143829	CCDC68	coiled-coil domain containing 68
chr7_-_107880492	0.128	NM_001037132	NRCAM	neuronal cell adhesion molecule
chr15_+_77287688	0.128		PSTPIP1	proline-serine-threonine phosphatase interacting protein 1
chr11_+_1861431	0.128	NM_001145841	TNNI2	troponin I type 2 (skeletal, fast)
chr19_+_41281081	0.128	NM_001202553	MIA	melanoma inhibitory activity
chr11_-_79151694	0.128	NM_001098816	ODZ4	odz, odd Oz/ten-m homolog 4 (Drosophila)
chr8_-_127570465	0.128		FAM84B	family with sequence similarity 84, member B

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.09	4.47e-12	GO:0009987	cellular process
1.45	2.06e-11	GO:0002376	immune system process
1.55	4.04e-10	GO:0006955	immune response
1.20	1.26e-07	GO:0023052	signaling
1.20	5.77e-07	GO:0007165	signal transduction
1.26	3.78e-05	GO:0010467	gene expression
1.10	3.87e-05	GO:0065007	biological regulation
1.25	8.28e-05	GO:0048583	regulation of response to stimulus
1.10	3.65e-04	GO:0050789	regulation of biological process
1.10	3.92e-04	GO:0050794	regulation of cellular process
1.15	4.21e-04	GO:0051716	cellular response to stimulus
1.24	4.31e-04	GO:0007166	cell surface receptor linked signaling pathway
1.46	1.19e-03	GO:0001775	cell activation
1.35	1.75e-03	GO:0006952	defense response
1.48	2.66e-03	GO:0002684	positive regulation of immune system process
1.37	3.22e-03	GO:0002682	regulation of immune system process
1.18	3.28e-03	GO:0048518	positive regulation of biological process
1.52	3.49e-03	GO:0045087	innate immune response
1.31	5.01e-03	GO:0032774	RNA biosynthetic process
2.09	5.15e-03	GO:0019080	viral genome expression
2.09	5.15e-03	GO:0019083	viral transcription
1.56	5.28e-03	GO:0006412	translation
1.15	7.26e-03	GO:0007275	multicellular organismal development
1.72	1.20e-02	GO:0051251	positive regulation of lymphocyte activation
1.95	1.24e-02	GO:0006414	translational elongation
1.80	1.32e-02	GO:0050870	positive regulation of T cell activation
2.02	1.50e-02	GO:0006415	translational termination
1.15	2.25e-02	GO:0048856	anatomical structure development
1.43	2.35e-02	GO:0050776	regulation of immune response
1.29	2.83e-02	GO:0009611	response to wounding
1.21	3.12e-02	GO:0016070	RNA metabolic process
1.75	3.63e-02	GO:0031016	pancreas development
1.17	4.88e-02	GO:0048522	positive regulation of cellular process

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.22	1.64e-05	GO:0044459	plasma membrane part
1.68	2.15e-03	GO:0005840	ribosome
2.10	2.51e-03	GO:0022626	cytosolic ribosome
1.25	2.68e-03	GO:0005887	integral to plasma membrane
1.23	7.78e-03	GO:0031226	intrinsic to plasma membrane
1.37	9.32e-03	GO:0030529	ribonucleoprotein complex
1.65	2.72e-02	GO:0044445	cytosolic part
1.06	4.04e-02	GO:0005737	cytoplasm

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.11	2.23e-06	GO:0005515	protein binding
1.05	6.81e-03	GO:0005488	binding
3.51	4.47e-02	GO:0050664	oxidoreductase activity, acting on NADH or NADPH, oxygen as acceptor