Motif ID: SPZ1.p2

Z-value: 0.852


Transcription factors associated with SPZ1.p2:

Gene SymbolEntrez IDGene Name
SPZ1 84654 spermatogenic leucine zipper 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
SPZ1chr5_+_79615789-0.147.5e-01Click!


Activity profile for motif SPZ1.p2.

activity profile for motif SPZ1.p2


Sorted Z-values histogram for motif SPZ1.p2

Sorted Z-values for motif SPZ1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of SPZ1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr6_+_72596699 0.399 RIMS1
regulating synaptic membrane exocytosis 1
chr9_+_12775713 0.377 C9orf150
chromosome 9 open reading frame 150
chr19_+_17581276 0.328 NM_198580
 SLC27A1
solute carrier family 27 (fatty acid transporter), member 1
chr1_-_935352 0.300 HES4
hairy and enhancer of split 4 (Drosophila)
chr1_+_27668499 0.291 SYTL1
synaptotagmin-like 1
chr19_+_35739838 0.289 LSR
lipolysis stimulated lipoprotein receptor
chr19_-_6720585 0.284 NM_000064
 C3
complement component 3
chr1_-_32801606 0.254 NM_023009
 MARCKSL1
MARCKS-like 1
chr1_-_184006491 0.234 GLT25D2
glycosyltransferase 25 domain containing 2
chr3_-_18466759 0.230 NM_001195470
NM_002971
 SATB1

SATB homeobox 1

chr10_+_111969988 0.224 NM_001008541
 MXI1
MAX interactor 1
chr2_+_46524448 0.223 NM_001430
 EPAS1
endothelial PAS domain protein 1
chr6_+_72596648 0.213 NM_014989
 RIMS1
regulating synaptic membrane exocytosis 1
chr11_-_120008219 0.209 TRIM29
tripartite motif containing 29
chr19_+_35739519 0.207 NM_015925
NM_205834
NM_205835
 LSR


lipolysis stimulated lipoprotein receptor


chr17_-_42200957 0.205 HDAC5
histone deacetylase 5
chr16_+_29912146 0.204 NM_181718
 ASPHD1
aspartate beta-hydroxylase domain containing 1
chr6_+_72596405 0.198 RIMS1
regulating synaptic membrane exocytosis 1
chr7_+_94285620 0.196 NM_001040152
NM_001184961
NM_001184962
NM_015068
 PEG10



paternally expressed 10



chr8_+_104512975 0.194 NM_001100117
 RIMS2
regulating synaptic membrane exocytosis 2

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 88 entries
enrichment   p-value GO term description
2.51 3.15e-02 GO:0045995 regulation of embryonic development
1.88 3.84e-03 GO:0006184 GTP catabolic process
1.87 2.60e-03 GO:0046039 GTP metabolic process
1.82 2.98e-02 GO:0016055 Wnt receptor signaling pathway
1.70 8.82e-07 GO:0007264 small GTPase mediated signal transduction
1.69 2.18e-05 GO:0007411 axon guidance
1.67 9.77e-03 GO:0048011 nerve growth factor receptor signaling pathway
1.65 1.76e-06 GO:0048667 cell morphogenesis involved in neuron differentiation
1.64 4.39e-06 GO:0007409 axonogenesis
1.63 3.18e-06 GO:0048812 neuron projection morphogenesis
1.60 1.53e-07 GO:0048666 neuron development
1.60 3.14e-06 GO:0031175 neuron projection development
1.59 3.82e-06 GO:0000904 cell morphogenesis involved in differentiation
1.58 4.36e-03 GO:0060284 regulation of cell development
1.57 2.91e-02 GO:0051960 regulation of nervous system development
1.55 4.45e-07 GO:0030030 cell projection organization
1.55 2.31e-05 GO:0032990 cell part morphogenesis
1.55 4.23e-05 GO:0048858 cell projection morphogenesis
1.54 1.50e-07 GO:0030182 neuron differentiation
1.53 1.14e-09 GO:0048699 generation of neurons

Gene overrepresentation in compartment category:

Showing 1 to 12 of 12 entries
enrichment   p-value GO term description
1.37 6.49e-03 GO:0030054 cell junction
1.20 2.74e-02 GO:0005856 cytoskeleton
1.19 3.38e-03 GO:0005829 cytosol
1.17 1.90e-02 GO:0044459 plasma membrane part
1.12 6.94e-11 GO:0005737 cytoplasm
1.11 7.71e-04 GO:0005634 nucleus
1.08 1.54e-10 GO:0005622 intracellular
1.08 5.87e-10 GO:0044424 intracellular part
1.07 1.75e-04 GO:0043229 intracellular organelle
1.07 1.84e-04 GO:0043226 organelle
1.07 1.00e-02 GO:0043231 intracellular membrane-bounded organelle
1.07 1.36e-02 GO:0043227 membrane-bounded organelle

Gene overrepresentation in function category:

Showing 1 to 16 of 16 entries
enrichment   p-value GO term description
1.51 2.33e-02 GO:0008134 transcription factor binding
1.50 1.88e-05 GO:0008092 cytoskeletal protein binding
1.47 4.10e-02 GO:0003779 actin binding
1.45 7.04e-09 GO:0001071 nucleic acid binding transcription factor activity
1.45 7.04e-09 GO:0003700 sequence-specific DNA binding transcription factor activity
1.45 2.26e-02 GO:0019001 guanyl nucleotide binding
1.45 2.26e-02 GO:0032561 guanyl ribonucleotide binding
1.45 2.62e-02 GO:0005525 GTP binding
1.44 2.84e-05 GO:0043565 sequence-specific DNA binding
1.34 2.69e-03 GO:0016301 kinase activity
1.33 1.80e-04 GO:0030528 transcription regulator activity
1.33 9.16e-03 GO:0016773 phosphotransferase activity, alcohol group as acceptor
1.33 4.84e-02 GO:0004672 protein kinase activity
1.29 9.98e-03 GO:0016772 transferase activity, transferring phosphorus-containing groups
1.16 1.50e-14 GO:0005515 protein binding
1.08 1.39e-10 GO:0005488 binding