Motif ID: SRF.p3

Z-value: 1.074


Transcription factors associated with SRF.p3:

Gene SymbolEntrez IDGene Name
SRF 6722 serum response factor (c-fos serum response element-binding transcription factor)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
SRFchr6_+_43138919-0.147.4e-01Click!


Activity profile for motif SRF.p3.

activity profile for motif SRF.p3


Sorted Z-values histogram for motif SRF.p3

Sorted Z-values for motif SRF.p3



Network of associatons between targets according to the STRING database.



First level regulatory network of SRF.p3

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr20_+_35169876 3.843 NM_006097
NM_181526
 MYL9

myosin, light chain 9, regulatory

chr20_+_35169897 3.229 MYL9
myosin, light chain 9, regulatory
chr10_-_64576123 2.311 NM_000399
NM_001136177
NM_001136179
 EGR2


early growth response 2


chr10_-_64576074 2.250 EGR2
early growth response 2
chr3_-_151987332 1.968 LOC401093
uncharacterized LOC401093
chr5_+_137801166 1.766 EGR1
early growth response 1
chr9_+_36136710 1.386 NM_022343
 GLIPR2
GLI pathogenesis-related 2
chr11_+_117070039 1.379 NM_001001522
NM_003186
 TAGLN

transgelin

chr19_+_2476122 1.306 NM_015675
 GADD45B
growth arrest and DNA-damage-inducible, beta
chr5_+_137801178 1.256 NM_001964
 EGR1
early growth response 1
chr9_-_79520878 1.240 NM_015225
 PRUNE2
prune homolog 2 (Drosophila)
chr10_+_31610063 1.095 NM_001128128
NM_001174094
 ZEB1

zinc finger E-box binding homeobox 1

chr14_-_53417808 1.012 NM_001134999
NM_001135000
NM_006832
 FERMT2


fermitin family member 2


chr5_+_92918924 0.978 NM_005654
 NR2F1
nuclear receptor subfamily 2, group F, member 1
chr9_+_92219926 0.885 NM_006705
 GADD45G
growth arrest and DNA-damage-inducible, gamma
chr10_-_90712510 0.634 NM_001613
 ACTA2
actin, alpha 2, smooth muscle, aorta
chr11_-_119294242 0.629 NM_006288
 THY1
Thy-1 cell surface antigen
chr20_+_33146500 0.610 NM_032514
 MAP1LC3A
microtubule-associated protein 1 light chain 3 alpha
chr7_-_27183225 0.564 NM_019102
 HOXA5
homeobox A5
chr3_-_46904879 0.550 NM_000258
 MYL3
myosin, light chain 3, alkali; ventricular, skeletal, slow

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 14 of 14 entries
enrichment   p-value GO term description
12.91 1.06e-03 GO:0070252 actin-mediated cell contraction
11.37 1.41e-02 GO:0030049 muscle filament sliding
11.37 1.41e-02 GO:0033275 actin-myosin filament sliding
9.62 8.29e-03 GO:0030048 actin filament-based movement
7.10 1.11e-06 GO:0006936 muscle contraction
6.93 4.78e-07 GO:0003012 muscle system process
4.57 1.52e-02 GO:0007517 muscle organ development
3.90 9.10e-03 GO:0030029 actin filament-based process
2.09 4.00e-02 GO:0010033 response to organic substance
1.84 2.54e-02 GO:0030154 cell differentiation
1.59 1.28e-02 GO:0023052 signaling
1.51 1.49e-03 GO:0032501 multicellular organismal process
1.39 1.57e-03 GO:0050789 regulation of biological process
1.38 6.40e-04 GO:0065007 biological regulation

Gene overrepresentation in compartment category:

Showing 1 to 20 of 21 entries
enrichment   p-value GO term description
15.58 2.18e-02 GO:0005859 muscle myosin complex
14.02 7.33e-04 GO:0032432 actin filament bundle
14.02 3.38e-02 GO:0016460 myosin II complex
12.74 1.32e-03 GO:0042641 actomyosin
12.52 8.82e-03 GO:0001725 stress fiber
11.68 7.36e-05 GO:0031674 I band
10.01 2.37e-08 GO:0030017 sarcomere
9.31 1.49e-08 GO:0044449 contractile fiber part
9.22 4.01e-02 GO:0030018 Z disc
9.12 4.66e-09 GO:0043292 contractile fiber
9.06 2.18e-08 GO:0030016 myofibril
5.67 1.78e-02 GO:0005925 focal adhesion
5.39 2.52e-02 GO:0005924 cell-substrate adherens junction
5.19 3.29e-02 GO:0030055 cell-substrate junction
5.15 1.95e-07 GO:0015629 actin cytoskeleton
2.05 1.33e-03 GO:0005856 cytoskeleton
1.31 1.27e-03 GO:0005737 cytoplasm
1.22 2.68e-02 GO:0043229 intracellular organelle
1.22 3.01e-02 GO:0043226 organelle
1.20 4.16e-03 GO:0044424 intracellular part

Gene overrepresentation in function category:

Showing 1 to 5 of 5 entries
enrichment   p-value GO term description
9.78 7.04e-03 GO:0008307 structural constituent of muscle
3.35 1.09e-02 GO:0003779 actin binding
2.59 3.61e-02 GO:0008092 cytoskeletal protein binding
1.32 9.84e-03 GO:0005515 protein binding
1.17 1.97e-02 GO:0005488 binding