Motif ID: STAT2,4,6.p2

Z-value: 0.586


Transcription factors associated with STAT2,4,6.p2:

Gene SymbolEntrez IDGene Name
STAT2 6773 signal transducer and activator of transcription 2, 113kDa
STAT4 6775 signal transducer and activator of transcription 4
STAT6 6778 signal transducer and activator of transcription 6, interleukin-4 induced

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
STAT4chr2_-_192015934,
chr2_-_192016293,
chr2_-_192015706		-0.601.2e-01Click!
STAT2chr12_-_56753916-0.285.0e-01Click!
STAT6chr12_-_575051760.206.3e-01Click!


Activity profile for motif STAT2,4,6.p2.

activity profile for motif STAT2,4,6.p2


Sorted Z-values histogram for motif STAT2,4,6.p2

Sorted Z-values for motif STAT2,4,6.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of STAT2,4,6.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr5_+_71502700 0.303 MAP1B
microtubule-associated protein 1B
chr11_-_133715368 0.251 NM_174927
 SPATA19
spermatogenesis associated 19
chr3_-_112564789 0.201 NM_001008784
NM_001199215
 CD200R1L

CD200 receptor 1-like

chr9_-_89562103 0.181 NM_002048
 GAS1
growth arrest-specific 1
chr4_+_41258895 0.170 NM_004181
 UCHL1
ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
chr4_+_41258909 0.166 UCHL1
ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
chr1_-_31845818 0.163 NM_004102
 FABP3
fatty acid binding protein 3, muscle and heart (mammary-derived growth inhibitor)
chr4_+_41258941 0.158 UCHL1
ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
chr14_+_24779356 0.151 NM_001164692
NM_019839
 LTB4R2

leukotriene B4 receptor 2

chr2_-_38303265 0.138 CYP1B1
cytochrome P450, family 1, subfamily B, polypeptide 1
chr12_-_42877785 0.137 NM_001144882
NM_001144883
 PRICKLE1

prickle homolog 1 (Drosophila)

chr1_+_186798031 0.135 NM_024420
 PLA2G4A
phospholipase A2, group IVA (cytosolic, calcium-dependent)
chr8_+_30601666 0.135 NM_005671
 UBXN8
UBX domain protein 8
chr2_+_33701320 0.131 NM_001139488
 RASGRP3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr12_-_42877743 0.130 PRICKLE1
prickle homolog 1 (Drosophila)
chr5_+_57878901 0.129 NM_138453
 RAB3C
RAB3C, member RAS oncogene family
chr5_-_138210992 0.124 CTNNA1
LRRTM2
catenin (cadherin-associated protein), alpha 1, 102kDa
leucine rich repeat transmembrane neuronal 2
chr4_+_55095263 0.123 NM_006206
 PDGFRA
platelet-derived growth factor receptor, alpha polypeptide
chr15_+_33010174 0.120 NM_001191322
NM_001191323
NM_013372
 GREM1


gremlin 1


chr3_+_14166552 0.118 TMEM43
transmembrane protein 43

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 8 of 8 entries
enrichment   p-value GO term description
1.64 1.32e-02 GO:0007409 axonogenesis
1.63 9.77e-03 GO:0048812 neuron projection morphogenesis
1.60 3.00e-02 GO:0048667 cell morphogenesis involved in neuron differentiation
1.57 1.70e-02 GO:0032990 cell part morphogenesis
1.57 2.07e-02 GO:0048858 cell projection morphogenesis
1.42 2.93e-02 GO:0040011 locomotion
1.33 8.78e-03 GO:0007399 nervous system development
1.08 1.87e-04 GO:0009987 cellular process

Gene overrepresentation in compartment category:

Showing 1 to 5 of 5 entries
enrichment   p-value GO term description
2.06 4.62e-02 GO:0030055 cell-substrate junction
1.80 4.52e-03 GO:0005635 nuclear envelope
1.78 9.11e-03 GO:0016323 basolateral plasma membrane
1.33 2.25e-04 GO:0012505 endomembrane system
1.22 3.06e-02 GO:0044428 nuclear part

Gene overrepresentation in function category:

Showing 1 to 4 of 4 entries
enrichment   p-value GO term description
2.75 1.20e-02 GO:0004896 cytokine receptor activity
2.35 1.35e-03 GO:0019955 cytokine binding
1.12 3.93e-04 GO:0005515 protein binding
1.07 6.90e-04 GO:0005488 binding