Motif ID: TBP.p2

Z-value: 1.912


Transcription factors associated with TBP.p2:

Gene SymbolEntrez IDGene Name
TBP 6908 TATA box binding protein

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
TBPchr6_+_1708634200.314.6e-01Click!


Activity profile for motif TBP.p2.

activity profile for motif TBP.p2


Sorted Z-values histogram for motif TBP.p2

Sorted Z-values for motif TBP.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of TBP.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_+_153003677 3.980 NM_003125
SPRR1B
small proline-rich protein 1B
chr12_-_52886971 3.525 NM_005554
KRT6A
keratin 6A
chr12_-_52845862 3.286 NM_005555
KRT6B
keratin 6B
chr12_-_52867521 2.737 NM_173086
KRT6C
keratin 6C
chr11_+_18287807 2.450 NM_000331
NM_001178006
NM_199161
SAA1


serum amyloid A1


chr1_-_153363544 2.417 NM_002964
S100A8
S100 calcium binding protein A8
chr11_-_18270167 2.290 NM_001199744
NM_001127380
NM_030754
SAA2-SAA4
SAA2

SAA2-SAA4 readthrough
serum amyloid A2

chr9_-_33447527 2.278 NM_004925
AQP3
aquaporin 3 (Gill blood group)
chr19_-_6720585 2.208 NM_000064
C3
complement component 3
chr1_+_153330329 2.162 NM_002965
S100A9
S100 calcium binding protein A9
chr1_-_153029987 2.058 NM_005988
SPRR2A
small proline-rich protein 2A
chr17_-_39507055 1.858 NM_004138
KRT33A
keratin 33A
chr11_-_102651321 1.823 NM_002425
MMP10
matrix metallopeptidase 10 (stromelysin 2)
chr14_+_75745480 1.775 NM_005252
FOS
FBJ murine osteosarcoma viral oncogene homolog
chr3_+_193853930 1.726 NM_005524
HES1
hairy and enhancer of split 1, (Drosophila)
chr17_-_39780762 1.646 NM_000422
KRT17
keratin 17
chr15_-_63674074 1.561 NM_001218
NM_206925
CA12

carbonic anhydrase XII

chr1_+_152881022 1.555 NM_005547
IVL
involucrin
chr1_-_59042827 1.548 TACSTD2
tumor-associated calcium signal transducer 2
chr15_-_63673918 1.516 CA12
carbonic anhydrase XII
chr3_+_193853937 1.452 HES1
hairy and enhancer of split 1, (Drosophila)
chr8_+_24771276 1.427 NEFM
neurofilament, medium polypeptide
chr12_-_52685249 1.388 NM_002281
KRT81
keratin 81
chr8_+_24771268 1.385 NM_005382
NEFM
neurofilament, medium polypeptide
chr6_-_2842069 1.384 NM_030666
SERPINB1
serpin peptidase inhibitor, clade B (ovalbumin), member 1
chr12_+_13044352 1.381 GPRC5A
G protein-coupled receptor, family C, group 5, member A
chr8_+_86376130 1.353 NM_000067
CA2
carbonic anhydrase II
chr22_+_29876180 1.316 NM_021076
NEFH
neurofilament, heavy polypeptide
chr2_-_122042767 1.310 NM_014553
TFCP2L1
transcription factor CP2-like 1
chr1_-_156675237 1.202 NM_001878
NM_001199723
CRABP2

cellular retinoic acid binding protein 2

chr6_+_26124372 1.176 NM_003512
HIST1H2AC
histone cluster 1, H2ac
chr12_-_53298765 1.174 NM_002273
KRT8
keratin 8
chr1_-_153013593 1.158 NM_006945
SPRR2D
small proline-rich protein 2D
chr17_-_38938785 1.140 NM_181537
KRT27
keratin 27
chr4_+_75310852 1.134 NM_001657
AREG
amphiregulin
chr10_-_45474210 1.112 NM_007021
C10orf10
chromosome 10 open reading frame 10
chr17_-_39675078 1.112 NM_002275
KRT15
keratin 15
chr17_+_39382878 1.109 NM_031961
KRTAP9-2
keratin associated protein 9-2
chr10_-_116418056 1.094 NM_002313
ABLIM1
actin binding LIM protein 1
chr8_-_24814028 1.071 NM_006158
NEFL
neurofilament, light polypeptide
chr1_-_11714471 1.038 FBXO2
F-box protein 2
chr1_-_23885916 1.006 ID3
inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
chrX_-_133792497 1.003 NM_021796
PLAC1
placenta-specific 1
chr7_-_41742666 1.001 NM_002192
INHBA
inhibin, beta A
chr17_-_39768939 0.992 NM_005557
KRT16
keratin 16
chr20_-_44540685 0.988 PLTP
phospholipid transfer protein
chr1_-_153067000 0.978 NM_001024209
SPRR2E
small proline-rich protein 2E
chr12_+_8975149 0.904 NM_144670
A2ML1
alpha-2-macroglobulin-like 1
chr19_+_10381763 0.882 ICAM1
intercellular adhesion molecule 1
chr1_+_40420802 0.876 MFSD2A
major facilitator superfamily domain containing 2A
chr6_-_26216871 0.869 NM_003518
HIST1H2BG
NCALD
histone cluster 1, H2bg
neurocalcin delta
chr10_+_120789227 0.769 NM_199461
NANOS1
nanos homolog 1 (Drosophila)
chr3_+_186739643 0.763 NM_003032
ST6GAL1
ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
chrX_+_17393537 0.735 NM_198270
NHS
Nance-Horan syndrome (congenital cataracts and dental anomalies)
chr9_-_124989755 0.728 NM_001242334
LHX6
LIM homeobox 6
chr1_-_11714396 0.727 FBXO2
F-box protein 2
chr6_-_53409897 0.726 NM_001197115
NM_001498
GCLC

glutamate-cysteine ligase, catalytic subunit

chr19_+_8117645 0.724 NM_001201359
NM_005624
CCL25

chemokine (C-C motif) ligand 25

chr17_-_39661803 0.714 NM_002274
NM_153490
KRT13

keratin 13

chr6_-_27114577 0.714 NM_080593
HIST1H2BK
histone cluster 1, H2bk
chr1_-_153044083 0.711 NM_001017418
SPRR2B
small proline-rich protein 2B
chr9_+_130911731 0.690 NM_005564
LCN2
lipocalin 2
chr15_+_45722762 0.675 NM_032413
NM_197955
C15orf48

chromosome 15 open reading frame 48

chr16_+_57406398 0.672 NM_002996
CX3CL1
chemokine (C-X3-C motif) ligand 1
chr12_+_104850784 0.671 CHST11
carbohydrate (chondroitin 4) sulfotransferase 11
chr5_-_53606387 0.638 NM_019087
ARL15
ADP-ribosylation factor-like 15
chr2_-_241080072 0.627 NM_148961
OTOS
otospiralin
chr4_+_74735107 0.626 NM_001511
CXCL1
chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
chr7_-_559479 0.623 NM_002607
NM_033023
PDGFA

platelet-derived growth factor alpha polypeptide

chr11_+_1151578 0.620 MUC5AC
mucin 5AC, oligomeric mucus/gel-forming
chr19_-_2051222 0.602 NM_017572
NM_199054
MKNK2

MAP kinase interacting serine/threonine kinase 2

chr8_-_131028674 0.593 FAM49B
family with sequence similarity 49, member B
chr20_-_39317875 0.569 NM_005461
MAFB
v-maf musculoaponeurotic fibrosarcoma oncogene homolog B (avian)
chr1_+_152658598 0.559 NM_014357
LCE2B
late cornified envelope 2B
chr17_+_27573874 0.549 NM_005208
CRYBA1
crystallin, beta A1
chr1_+_16085245 0.532 NM_017556
FBLIM1
filamin binding LIM protein 1
chr7_-_16844606 0.531 NM_006408
AGR2
anterior gradient 2 homolog (Xenopus laevis)
chr6_+_14118002 0.529 CD83
CD83 molecule
chr11_+_68452007 0.527 GAL
galanin prepropeptide
chr17_-_39023461 0.519 NM_000223
KRT12
keratin 12
chr16_+_78056411 0.513 NM_005752
CLEC3A
C-type lectin domain family 3, member A
chr14_-_55369163 0.510 NM_000161
NM_001024024
NM_001024070
NM_001024071
GCH1



GTP cyclohydrolase 1



chr8_-_131028646 0.499 FAM49B
family with sequence similarity 49, member B
chr10_+_24497719 0.494 NM_001098501
NM_019590
KIAA1217

KIAA1217

chr15_-_75017710 0.494 NM_000499
CYP1A1
cytochrome P450, family 1, subfamily A, polypeptide 1
chr19_+_12902295 0.490 NM_002229
JUNB
jun B proto-oncogene
chr19_-_51487070 0.487 NM_139277
NM_001207053
NM_001243126
NM_005046
KLK7



kallikrein-related peptidase 7



chr3_+_70048882 0.486


chr12_+_101988746 0.481 NM_002465
NM_206819
NM_206820
NM_206821
MYBPC1



myosin binding protein C, slow type



chr17_-_48546174 0.481 NM_001267
CHAD
chondroadherin
chr12_+_13044493 0.480 GPRC5A
G protein-coupled receptor, family C, group 5, member A
chr6_-_26124130 0.472 NM_003526
HIST1H2BG
HIST1H2BC
histone cluster 1, H2bg
histone cluster 1, H2bc
chr7_-_25268057 0.470 NM_022150
NPVF
neuropeptide VF precursor
chr9_-_37034358 0.464 NM_016734
PAX5
paired box 5
chr17_+_56315786 0.464 NM_001160102
NM_006151
LPO

lactoperoxidase

chr19_+_13049428 0.460 CALR
calreticulin
chr19_-_33793441 0.442 CEBPA
CCAAT/enhancer binding protein (C/EBP), alpha
chr1_+_42619091 0.438 NM_007102
GUCA2B
guanylate cyclase activator 2B (uroguanylin)
chr11_-_5248180 0.436 NM_000518
HBB
hemoglobin, beta
chr1_-_23886284 0.433 NM_002167
ID3
inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
chr1_+_37940180 0.426 ZC3H12A
zinc finger CCCH-type containing 12A
chr4_-_46391393 0.425 NM_001114175
GABRA2
gamma-aminobutyric acid (GABA) A receptor, alpha 2
chr6_-_133035180 0.422 NM_004666
VNN1
vanin 1
chr19_+_13049413 0.417 NM_004343
CALR
calreticulin
chr17_+_32612686 0.416 NM_002986
CCL11
chemokine (C-C motif) ligand 11
chr8_-_48650703 0.415 NM_005195
CEBPD
CCAAT/enhancer binding protein (C/EBP), delta
chr1_-_228135587 0.415 NM_003395
WNT9A
wingless-type MMTV integration site family, member 9A
chr1_-_27481400 0.413 NM_003047
SLC9A1
solute carrier family 9 (sodium/hydrogen exchanger), member 1
chrX_+_84498993 0.409 NM_021998
ZNF711
zinc finger protein 711
chr19_+_8117887 0.408 CCL25
chemokine (C-C motif) ligand 25
chr22_-_27013959 0.396 NM_001887
CRYBB1
crystallin, beta B1
chr14_-_103989195 0.393 NM_001823
CKB
creatine kinase, brain
chr19_+_13049440 0.383 CALR
calreticulin
chr19_-_35981345 0.383 NM_001244847
NM_207392
KRTDAP

keratinocyte differentiation-associated protein

chr6_-_27100528 0.381 NM_021058
HIST1H2BJ
histone cluster 1, H2bj
chr3_-_27764197 0.367 EOMES
eomesodermin
chr12_+_41086189 0.363 NM_001843
NM_175038
CNTN1

contactin 1

chr1_-_43424536 0.357 SLC2A1
solute carrier family 2 (facilitated glucose transporter), member 1
chr6_+_127898318 0.355 NM_001010905
C6orf58
chromosome 6 open reading frame 58
chr21_-_32185560 0.353 NM_175857
KRTAP8-1
keratin associated protein 8-1
chr17_+_7387688 0.347 NM_000937
POLR2A
polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
chr19_+_859658 0.346 NM_001928
CFD
complement factor D (adipsin)
chr17_-_39684499 0.344 KRT19
keratin 19
chr19_+_41222915 0.344 NM_025194
ITPKC
inositol-trisphosphate 3-kinase C
chr6_-_2903461 0.342 NM_004155
SERPINB9
serpin peptidase inhibitor, clade B (ovalbumin), member 9
chr11_+_1860232 0.342 NM_003282
TNNI2
troponin I type 2 (skeletal, fast)
chr4_+_119199906 0.332 SNHG8
small nucleolar RNA host gene 8 (non-protein coding)
chr19_-_11591439 0.332 NM_001420
NM_032281
ELAVL3

ELAV (embryonic lethal, abnormal vision, Drosophila)-like 3 (Hu antigen C)

chr14_+_94492747 0.330 OTUB2
OTU domain, ubiquitin aldehyde binding 2
chr15_-_62457481 0.330 NM_001007595
C2CD4B
C2 calcium-dependent domain containing 4B
chr10_+_118380451 0.330 NM_005396
PNLIPRP2
pancreatic lipase-related protein 2
chr19_-_33793429 0.330 NM_004364
CEBPA
CCAAT/enhancer binding protein (C/EBP), alpha
chr10_-_69455926 0.328 NM_013266
CTNNA3
catenin (cadherin-associated protein), alpha 3
chr15_-_85201417 0.319 NMB
neuromedin B
chr6_+_33172418 0.317 NM_014234
HSD17B8
hydroxysteroid (17-beta) dehydrogenase 8
chr11_+_68451978 0.313 NM_015973
GAL
galanin prepropeptide
chr1_+_149822627 0.312 NM_001040874
NM_003516
HIST2H2AA4
HIST2H2AA3
histone cluster 2, H2aa4
histone cluster 2, H2aa3
chr7_+_116593354 0.311 NM_018412
NM_021908
ST7

suppression of tumorigenicity 7

chr4_+_74301932 0.310 NM_001134
AFP
alpha-fetoprotein
chr5_+_132209354 0.309 NM_052971
LEAP2
liver expressed antimicrobial peptide 2
chr8_-_48650683 0.307 CEBPD
CCAAT/enhancer binding protein (C/EBP), delta
chr1_+_17575592 0.306 NM_016233
PADI3
peptidyl arginine deiminase, type III
chr16_-_3030473 0.298 NM_004203
NM_182687
PKMYT1

protein kinase, membrane associated tyrosine/threonine 1

chr21_+_34398210 0.295 NM_005806
OLIG2
oligodendrocyte lineage transcription factor 2
chr8_-_23261626 0.294 LOXL2
lysyl oxidase-like 2
chr1_-_32801606 0.292 NM_023009
MARCKSL1
MARCKS-like 1
chr12_+_104850750 0.287 CHST11
carbohydrate (chondroitin 4) sulfotransferase 11
chr16_+_71392615 0.284 NM_001740
NM_007088
CALB2

calbindin 2

chr1_-_149858114 0.282 NM_003528
HIST2H2BE
histone cluster 2, H2be
chr3_+_148583042 0.280 NM_001870
CPA3
carboxypeptidase A3 (mast cell)
chr17_+_34431219 0.280 NM_002984
CCL4
chemokine (C-C motif) ligand 4
chr6_-_26197477 0.279 HIST1H3D
histone cluster 1, H3d
chr7_+_115863004 0.277 NM_152829
TES
testis derived transcript (3 LIM domains)
chr8_+_133879202 0.276 NM_003235
TG
thyroglobulin
chr1_+_6105980 0.275 NM_001199862
KCNAB2
potassium voltage-gated channel, shaker-related subfamily, beta member 2
chr14_-_103989112 0.273 CKB
creatine kinase, brain
chr2_+_113885137 0.272 NM_173842
IL1RN
interleukin 1 receptor antagonist
chr8_-_23261591 0.267 LOXL2
lysyl oxidase-like 2
chr20_+_2276612 0.266 NM_003245
TGM3
transglutaminase 3 (E polypeptide, protein-glutamine-gamma-glutamyltransferase)
chr16_+_71392637 0.263 CALB2
calbindin 2
chr17_+_79008945 0.263 NM_001144888
NM_006340
NM_017450
NM_017451
BAIAP2



BAI1-associated protein 2



chr17_+_7554239 0.261 NM_001678
ATP1B2
ATPase, Na+/K+ transporting, beta 2 polypeptide
chr6_-_27775683 0.260 NM_003519
HIST1H2BL
histone cluster 1, H2bl
chr17_-_39580657 0.259 NM_003770
KRT37
keratin 37
chr17_+_39394269 0.259 NM_031963
KRTAP9-8
keratin associated protein 9-8
chr6_+_111195986 0.257 NM_001634
NM_001033059
AMD1

adenosylmethionine decarboxylase 1

chr11_-_57148602 0.257 NM_006093
PRG3
proteoglycan 3
chr11_-_5255712 0.256 NM_000519
HBD
hemoglobin, delta
chr11_+_65190272 0.255


chr11_+_66188474 0.252 NM_178864
NPAS4
neuronal PAS domain protein 4
chr2_-_75426613 0.251 NM_001058
NM_015727
TACR1

tachykinin receptor 1

chr1_-_149783910 0.250 NM_001024599
NM_001161334
HIST2H2BF

histone cluster 2, H2bf

chr1_-_149814264 0.247 NM_001040874
NM_003516
HIST2H2AA4
HIST2H2AA3
histone cluster 2, H2aa4
histone cluster 2, H2aa3
chr1_+_233749749 0.246 NM_002245
KCNK1
potassium channel, subfamily K, member 1
chr5_-_57755787 0.245 NM_001252226
NM_006622
PLK2

polo-like kinase 2

chrX_+_153046422 0.244 NM_001170760
NM_001170761
NM_014370
SRPK3


SRSF protein kinase 3


chr7_-_16505292 0.242 NM_015464
SOSTDC1
sclerostin domain containing 1
chrX_-_30327479 0.241 NM_000475
NR0B1
nuclear receptor subfamily 0, group B, member 1
chr3_+_4535030 0.240 NM_001099952
NM_001168272
NM_002222
ITPR1


inositol 1,4,5-trisphosphate receptor, type 1


chr1_-_8086347 0.237 ERRFI1
ERBB receptor feedback inhibitor 1
chr8_+_1993157 0.234 NM_003970
MYOM2
myomesin (M-protein) 2, 165kDa
chr1_-_203155813 0.232 CHI3L1
chitinase 3-like 1 (cartilage glycoprotein-39)
chr15_+_45406518 0.226 NM_207581
DUOXA2
dual oxidase maturation factor 2
chr2_-_142889269 0.225 NM_018557
LRP1B
low density lipoprotein receptor-related protein 1B
chr8_-_23261632 0.222 LOXL2
lysyl oxidase-like 2
chr10_-_95170 0.222 NM_177987
TUBB8
tubulin, beta 8 class VIII
chr18_-_44556448 0.222 NM_145653
TCEB3C
transcription elongation factor B polypeptide 3C (elongin A3)
chr9_-_117568292 0.221 NM_005118
TNFSF15
tumor necrosis factor (ligand) superfamily, member 15
chr9_+_139557378 0.217 NM_016215
EGFL7
EGF-like-domain, multiple 7
chr7_+_100612903 0.215 NM_001164462
MUC12
mucin 12, cell surface associated
chr1_+_37940129 0.213 ZC3H12A
zinc finger CCCH-type containing 12A
chr12_+_52400725 0.212 NM_181711
GRASP
GRP1 (general receptor for phosphoinositides 1)-associated scaffold protein
chr1_+_247581350 0.212 NM_001127462
NM_001243133
NM_004895
NM_183395
NLRP3



NLR family, pyrin domain containing 3



chr17_+_79008958 0.208 BAIAP2
BAI1-associated protein 2
chr1_-_26393984 0.207 NM_032588
TRIM63
tripartite motif containing 63
chr7_+_116593554 0.206 ST7
suppression of tumorigenicity 7
chr16_+_56966025 0.203 HERPUD1
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
chr6_-_137815520 0.203 NM_175747
OLIG3
oligodendrocyte transcription factor 3
chr1_-_203155827 0.203 CHI3L1
chitinase 3-like 1 (cartilage glycoprotein-39)
chr7_+_94285676 0.202 NM_001172437
NM_001172438
PEG10

paternally expressed 10


Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
8.94 8.93e-14 GO:0006334 nucleosome assembly
8.48 3.36e-13 GO:0031497 chromatin assembly
8.06 1.16e-12 GO:0034728 nucleosome organization
7.76 2.98e-12 GO:0065004 protein-DNA complex assembly
7.34 1.12e-11 GO:0071824 protein-DNA complex subunit organization
2.07 1.27e-10 GO:0048513 organ development
6.48 2.17e-10 GO:0006323 DNA packaging
2.74 8.17e-10 GO:0006952 defense response
6.09 8.82e-10 GO:0006333 chromatin assembly or disassembly
5.56 6.98e-09 GO:0071103 DNA conformation change
1.63 2.25e-07 GO:0048856 anatomical structure development
3.05 2.40e-07 GO:0034621 cellular macromolecular complex subunit organization
1.67 4.33e-07 GO:0048731 system development
1.73 7.56e-07 GO:0006950 response to stress
3.36 9.51e-07 GO:0034622 cellular macromolecular complex assembly
1.40 3.91e-06 GO:0032501 multicellular organismal process
3.61 3.98e-06 GO:0006954 inflammatory response
2.34 4.37e-06 GO:0009888 tissue development
2.83 6.28e-06 GO:0009607 response to biotic stimulus
1.54 6.50e-06 GO:0007275 multicellular organismal development
1.50 7.32e-06 GO:0032502 developmental process
4.15 7.66e-06 GO:0008544 epidermis development
2.25 1.74e-05 GO:0051704 multi-organism process
2.89 6.40e-05 GO:0051707 response to other organism
2.22 9.55e-05 GO:0043933 macromolecular complex subunit organization
2.28 1.55e-04 GO:0071844 cellular component assembly at cellular level
2.27 1.92e-04 GO:0006955 immune response
1.63 2.14e-04 GO:0042221 response to chemical stimulus
8.16 3.33e-04 GO:0031424 keratinization
1.88 8.30e-04 GO:0002376 immune system process
2.06 8.51e-04 GO:0009611 response to wounding
2.16 3.22e-03 GO:0065003 macromolecular complex assembly
19.03 3.49e-03 GO:0045109 intermediate filament organization
9.99 5.41e-03 GO:0042743 hydrogen peroxide metabolic process
1.95 5.88e-03 GO:0070887 cellular response to chemical stimulus
1.88 6.36e-03 GO:0022607 cellular component assembly
17.13 6.81e-03 GO:0045672 positive regulation of osteoclast differentiation
3.01 7.82e-03 GO:0009617 response to bacterium
12.09 8.07e-03 GO:0045104 intermediate filament cytoskeleton organization
11.42 1.18e-02 GO:0042744 hydrogen peroxide catabolic process
1.74 1.60e-02 GO:0010033 response to organic substance
8.57 1.68e-02 GO:0070301 cellular response to hydrogen peroxide
5.35 1.96e-02 GO:0030216 keratinocyte differentiation
5.27 2.26e-02 GO:0019748 secondary metabolic process
6.85 2.29e-02 GO:0072593 reactive oxygen species metabolic process
10.28 2.35e-02 GO:0045103 intermediate filament-based process
2.78 2.70e-02 GO:0010035 response to inorganic substance
4.60 3.23e-02 GO:0045637 regulation of myeloid cell differentiation
6.53 3.35e-02 GO:0034614 cellular response to reactive oxygen species
6.53 3.35e-02 GO:0045639 positive regulation of myeloid cell differentiation
1.74 3.57e-02 GO:0044085 cellular component biogenesis
1.69 4.73e-02 GO:0051239 regulation of multicellular organismal process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
7.91 2.18e-22 GO:0005882 intermediate filament
6.85 5.85e-20 GO:0045111 intermediate filament cytoskeleton
13.70 1.23e-19 GO:0000786 nucleosome
3.31 5.77e-18 GO:0005615 extracellular space
2.21 7.63e-17 GO:0005576 extracellular region
2.83 5.01e-16 GO:0044421 extracellular region part
8.66 2.67e-14 GO:0032993 protein-DNA complex
7.94 2.29e-10 GO:0045095 keratin filament
1.67 4.85e-08 GO:0043228 non-membrane-bounded organelle
1.67 4.85e-08 GO:0043232 intracellular non-membrane-bounded organelle
4.02 9.18e-08 GO:0000785 chromatin
1.47 1.12e-05 GO:0032991 macromolecular complex
2.03 1.31e-05 GO:0044430 cytoskeletal part
1.81 1.52e-05 GO:0005856 cytoskeleton
13.32 7.70e-05 GO:0032982 myosin filament
11.42 2.61e-04 GO:0001533 cornified envelope
2.26 5.01e-03 GO:0044427 chromosomal part

Gene overrepresentation in function category:

enrichment   p-value GO term description
3.51 2.16e-15 GO:0005198 structural molecule activity
5.12 6.81e-11 GO:0005125 cytokine activity
9.68 9.47e-08 GO:0008009 chemokine activity
8.73 3.89e-07 GO:0042379 chemokine receptor binding
2.16 1.58e-06 GO:0005102 receptor binding
4.19 2.82e-06 GO:0005126 cytokine receptor binding
5.54 5.89e-06 GO:0005179 hormone activity
4.45 5.93e-05 GO:0046906 tetrapyrrole binding
4.46 1.32e-04 GO:0020037 heme binding
3.59 6.56e-04 GO:0001664 G-protein-coupled receptor binding
3.15 2.40e-03 GO:0005506 iron ion binding
4.83 1.02e-02 GO:0005200 structural constituent of cytoskeleton
6.09 1.15e-02 GO:0019825 oxygen binding
10.08 2.88e-02 GO:0005212 structural constituent of eye lens