Motif ID: TBP.p2

Z-value: 1.912


Transcription factors associated with TBP.p2:

Gene SymbolEntrez IDGene Name
TBP 6908 TATA box binding protein

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
TBPchr6_+_1708634200.314.6e-01Click!


Activity profile for motif TBP.p2.

activity profile for motif TBP.p2


Sorted Z-values histogram for motif TBP.p2

Sorted Z-values for motif TBP.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of TBP.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr1_+_153003677 3.980 NM_003125
 SPRR1B
small proline-rich protein 1B
chr12_-_52886971 3.525 NM_005554
 KRT6A
keratin 6A
chr12_-_52845862 3.286 NM_005555
 KRT6B
keratin 6B
chr12_-_52867521 2.737 NM_173086
 KRT6C
keratin 6C
chr11_+_18287807 2.450 NM_000331
NM_001178006
NM_199161
 SAA1


serum amyloid A1


chr1_-_153363544 2.417 NM_002964
 S100A8
S100 calcium binding protein A8
chr11_-_18270167 2.290 NM_001199744
NM_001127380
NM_030754
 SAA2-SAA4
SAA2

SAA2-SAA4 readthrough
serum amyloid A2

chr9_-_33447527 2.278 NM_004925
 AQP3
aquaporin 3 (Gill blood group)
chr19_-_6720585 2.208 NM_000064
 C3
complement component 3
chr1_+_153330329 2.162 NM_002965
 S100A9
S100 calcium binding protein A9
chr1_-_153029987 2.058 NM_005988
 SPRR2A
small proline-rich protein 2A
chr17_-_39507055 1.858 NM_004138
 KRT33A
keratin 33A
chr11_-_102651321 1.823 NM_002425
 MMP10
matrix metallopeptidase 10 (stromelysin 2)
chr14_+_75745480 1.775 NM_005252
 FOS
FBJ murine osteosarcoma viral oncogene homolog
chr3_+_193853930 1.726 NM_005524
 HES1
hairy and enhancer of split 1, (Drosophila)
chr17_-_39780762 1.646 NM_000422
 KRT17
keratin 17
chr15_-_63674074 1.561 NM_001218
NM_206925
 CA12

carbonic anhydrase XII

chr1_+_152881022 1.555 NM_005547
 IVL
involucrin
chr1_-_59042827 1.548 TACSTD2
tumor-associated calcium signal transducer 2
chr15_-_63673918 1.516 CA12
carbonic anhydrase XII

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 52 entries
enrichment   p-value GO term description
19.03 3.49e-03 GO:0045109 intermediate filament organization
17.13 6.81e-03 GO:0045672 positive regulation of osteoclast differentiation
12.09 8.07e-03 GO:0045104 intermediate filament cytoskeleton organization
11.42 1.18e-02 GO:0042744 hydrogen peroxide catabolic process
10.28 2.35e-02 GO:0045103 intermediate filament-based process
9.99 5.41e-03 GO:0042743 hydrogen peroxide metabolic process
8.94 8.93e-14 GO:0006334 nucleosome assembly
8.57 1.68e-02 GO:0070301 cellular response to hydrogen peroxide
8.48 3.36e-13 GO:0031497 chromatin assembly
8.16 3.33e-04 GO:0031424 keratinization
8.06 1.16e-12 GO:0034728 nucleosome organization
7.76 2.98e-12 GO:0065004 protein-DNA complex assembly
7.34 1.12e-11 GO:0071824 protein-DNA complex subunit organization
6.85 2.29e-02 GO:0072593 reactive oxygen species metabolic process
6.53 3.35e-02 GO:0034614 cellular response to reactive oxygen species
6.53 3.35e-02 GO:0045639 positive regulation of myeloid cell differentiation
6.48 2.17e-10 GO:0006323 DNA packaging
6.09 8.82e-10 GO:0006333 chromatin assembly or disassembly
5.56 6.98e-09 GO:0071103 DNA conformation change
5.35 1.96e-02 GO:0030216 keratinocyte differentiation

Gene overrepresentation in compartment category:

Showing 1 to 17 of 17 entries
enrichment   p-value GO term description
13.70 1.23e-19 GO:0000786 nucleosome
13.32 7.70e-05 GO:0032982 myosin filament
11.42 2.61e-04 GO:0001533 cornified envelope
8.66 2.67e-14 GO:0032993 protein-DNA complex
7.94 2.29e-10 GO:0045095 keratin filament
7.91 2.18e-22 GO:0005882 intermediate filament
6.85 5.85e-20 GO:0045111 intermediate filament cytoskeleton
4.02 9.18e-08 GO:0000785 chromatin
3.31 5.77e-18 GO:0005615 extracellular space
2.83 5.01e-16 GO:0044421 extracellular region part
2.26 5.01e-03 GO:0044427 chromosomal part
2.21 7.63e-17 GO:0005576 extracellular region
2.03 1.31e-05 GO:0044430 cytoskeletal part
1.81 1.52e-05 GO:0005856 cytoskeleton
1.67 4.85e-08 GO:0043228 non-membrane-bounded organelle
1.67 4.85e-08 GO:0043232 intracellular non-membrane-bounded organelle
1.47 1.12e-05 GO:0032991 macromolecular complex

Gene overrepresentation in function category:

Showing 1 to 14 of 14 entries
enrichment   p-value GO term description
10.08 2.88e-02 GO:0005212 structural constituent of eye lens
9.68 9.47e-08 GO:0008009 chemokine activity
8.73 3.89e-07 GO:0042379 chemokine receptor binding
6.09 1.15e-02 GO:0019825 oxygen binding
5.54 5.89e-06 GO:0005179 hormone activity
5.12 6.81e-11 GO:0005125 cytokine activity
4.83 1.02e-02 GO:0005200 structural constituent of cytoskeleton
4.46 1.32e-04 GO:0020037 heme binding
4.45 5.93e-05 GO:0046906 tetrapyrrole binding
4.19 2.82e-06 GO:0005126 cytokine receptor binding
3.59 6.56e-04 GO:0001664 G-protein-coupled receptor binding
3.51 2.16e-15 GO:0005198 structural molecule activity
3.15 2.40e-03 GO:0005506 iron ion binding
2.16 1.58e-06 GO:0005102 receptor binding