Motif ID: TCF4_dimer.p2

Z-value: 2.149


Transcription factors associated with TCF4_dimer.p2:

Gene SymbolEntrez IDGene Name
TCF4 6925 transcription factor 4

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
TCF4chr18_-_532570330.393.4e-01Click!


Activity profile for motif TCF4_dimer.p2.

activity profile for motif TCF4_dimer.p2


Sorted Z-values histogram for motif TCF4_dimer.p2

Sorted Z-values for motif TCF4_dimer.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of TCF4_dimer.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr17_+_39382878 2.726 NM_031961
 KRTAP9-2
keratin associated protein 9-2
chr9_-_97401588 2.019 FBP1
fructose-1,6-bisphosphatase 1
chr15_+_74218962 1.997 LOXL1
lysyl oxidase-like 1
chr11_-_694842 1.766 DEAF1
deformed epidermal autoregulatory factor 1 (Drosophila)
chr6_+_124125068 1.609 NM_001040214
NM_153355
 NKAIN2

Na+/K+ transporting ATPase interacting 2

chr11_-_63933493 1.475 NM_014067
 MACROD1
MACRO domain containing 1
chrX_-_107018889 1.328 TSC22D3
TSC22 domain family, member 3
chr1_+_89990396 1.297 NM_001134476
 LRRC8B
leucine rich repeat containing 8 family, member B
chr9_-_97401746 1.294 FBP1
fructose-1,6-bisphosphatase 1
chr15_+_74218786 1.282 NM_005576
 LOXL1
lysyl oxidase-like 1
chr15_+_74218794 1.259 LOXL1
lysyl oxidase-like 1
chr9_-_97401833 1.160 NM_000507
 FBP1
fructose-1,6-bisphosphatase 1
chr10_-_21462987 1.137 NEBL
nebulette
chr9_-_131940538 1.127 NM_203434
 IER5L
immediate early response 5-like
chr11_-_63933204 1.115 MACROD1
MACRO domain containing 1
chr3_-_87040246 1.107 NM_016206
 VGLL3
vestigial like 3 (Drosophila)
chr3_-_178789535 1.100 ZMAT3
zinc finger, matrin-type 3
chr16_-_28550324 1.087 NM_001042483
NM_012385
 NUPR1

nuclear protein, transcriptional regulator, 1

chr3_-_178789597 1.078 NM_022470
NM_152240
 ZMAT3

zinc finger, matrin-type 3

chr21_+_27011588 1.072 NM_021219
 JAM2
junctional adhesion molecule 2

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 20 entries
enrichment   p-value GO term description
2.31 1.83e-03 GO:0032313 regulation of Rab GTPase activity
2.31 1.83e-03 GO:0032483 regulation of Rab protein signal transduction
1.51 3.91e-03 GO:0031329 regulation of cellular catabolic process
1.47 7.84e-03 GO:0009894 regulation of catabolic process
1.25 5.31e-04 GO:0035556 intracellular signal transduction
1.24 1.04e-03 GO:0009966 regulation of signal transduction
1.22 6.12e-04 GO:0023051 regulation of signaling
1.19 6.04e-04 GO:0048523 negative regulation of cellular process
1.18 1.07e-03 GO:0048519 negative regulation of biological process
1.18 2.02e-02 GO:0048583 regulation of response to stimulus
1.15 2.79e-02 GO:0048522 positive regulation of cellular process
1.14 1.27e-02 GO:0048731 system development
1.14 2.14e-02 GO:0048518 positive regulation of biological process
1.12 4.06e-03 GO:0051716 cellular response to stimulus
1.12 2.53e-02 GO:0080090 regulation of primary metabolic process
1.12 3.55e-02 GO:0007165 signal transduction
1.09 6.33e-05 GO:0050794 regulation of cellular process
1.08 3.51e-04 GO:0065007 biological regulation
1.08 5.64e-04 GO:0050789 regulation of biological process
1.05 4.64e-04 GO:0009987 cellular process

Gene overrepresentation in compartment category:

Showing 1 to 11 of 11 entries
enrichment   p-value GO term description
1.41 2.12e-02 GO:0005743 mitochondrial inner membrane
1.40 1.50e-02 GO:0019866 organelle inner membrane
1.39 1.54e-03 GO:0031966 mitochondrial membrane
1.36 6.00e-03 GO:0005740 mitochondrial envelope
1.20 3.53e-05 GO:0005829 cytosol
1.12 1.08e-13 GO:0005737 cytoplasm
1.10 1.58e-05 GO:0044444 cytoplasmic part
1.08 1.98e-13 GO:0005622 intracellular
1.07 6.51e-12 GO:0044424 intracellular part
1.05 2.11e-02 GO:0043229 intracellular organelle
1.05 2.49e-02 GO:0043226 organelle

Gene overrepresentation in function category:

Showing 1 to 4 of 4 entries
enrichment   p-value GO term description
2.27 8.73e-04 GO:0005097 Rab GTPase activator activity
1.24 9.15e-03 GO:0030528 transcription regulator activity
1.13 2.33e-12 GO:0005515 protein binding
1.05 2.65e-06 GO:0005488 binding